NCT07011992

A Study to Assess the Effects of BPN14770 on Rosuvastatin

A Phase 1, Open-label, 1-Sequence Crossover, Drug-drug Interaction Study to Assess the Effect of Repeated Doses of BPN14770 on the Pharmacokinetics of Rosuvastatin in Healthy Adult Participants

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Shionogi · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The primary objective of this study is to investigate the effects of BPN14770 on the pharmacokinetics of the breast cancer resistance protein and organic anion transporting polypeptide 1B1 substrate rosuvastatin in healthy adults.

Conditions

• Healthy Participants

Interventions

Type	Name	Description
DRUG	Rosuvastatin	Oral tablet
DRUG	BPN14770	Oral capsule

Timeline

• Start date: 2025-07-18
• Primary completion: 2025-07-31
• Completion: 2025-08-07
• First posted: 2025-06-10
• Last updated: 2025-08-14

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study