Clinical Trials Directory

Trials / Completed

CompletedNCT01993940

Efficacy and Safety of Naldemedine in Treating Opioid-induced Constipation

A Randomized, Double-blind, Placebo-controlled, Parallel-group Study of Naldemedine in the Treatment of Opioid-induced Constipation in Subjects With Non-malignant Chronic Pain Receiving Opioid Therapy

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
553 (actual)
Sponsor
Shionogi · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of naldemedine in the treatment of opioid-induced constipation (OIC) in adults with non-malignant chronic pain who are not using laxatives.

Conditions

Interventions

TypeNameDescription
DRUGNaldemedineNaldemedine 0.2 mg tablet taken orally once a day
DRUGPlaceboPlacebo tablet taken orally once a day

Timeline

Start date
2013-11-04
Primary completion
2015-06-09
Completion
2015-06-09
First posted
2013-11-25
Last updated
2017-05-30
Results posted
2017-05-30

Locations

49 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01993940. Inclusion in this directory is not an endorsement.