Clinical Trials Directory

Trials / Completed

CompletedNCT01965652

Long Term Safety of Naldemedine

A Randomized Double-blind, Placebo-controlled, Parallel-group, Multicenter, Phase 3 Study to Evaluate the Long-term Safety of Naldemedine for the Treatment of Opioid-induced Constipation in Subjects With Non-malignant Chronic Pain Receiving Opioid Therapy

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
1,246 (actual)
Sponsor
Shionogi · Industry
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the long-term safety of naldemedine for the treatment of constipation due to opioid therapy.

Conditions

Interventions

TypeNameDescription
DRUGNaldemedineNaldemedine 0.2 mg tablet taken orally once a day
DRUGPlaceboPlacebo tablet taken orally once a day

Timeline

Start date
2013-09-24
Primary completion
2016-01-12
Completion
2016-01-12
First posted
2013-10-18
Last updated
2018-04-18
Results posted
2017-05-30

Locations

186 sites across 16 countries: United States, Australia, Austria, Canada, Czechia, Denmark, France, Germany, Hungary, Israel, Italy, Poland, South Africa, Spain, Sweden, United Kingdom

Source: ClinicalTrials.gov record NCT01965652. Inclusion in this directory is not an endorsement.