Trials / Not Yet Recruiting
Not Yet RecruitingNCT06740942
Imaging and Serological Biomarkers of Autonomic Dysfunction After Ischemic Stroke
- Status
- Not Yet Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The goal of this observational study is to * to investigate the prevalence and time course of autonomic dysfunction in acute ischemic stroke patients; * to evaluate the influence of lesion location on autonomic dysfunction; * to identify patterns of structural and functional brain connectivity within the central autonomic control circuits associated with autonomic dysfunction; and * to explore causal models of the link between brain lesions; cardiac, immunological and endocrine biomarkers; and dysautonomia. Researchers will compare patients with acute ischemic stroke to patients with transient ischemic attacks to study the effect of acute ischemic brain lesions. Participants will * undergo cardiovascular autonomic function testing; * receive structural and functional MR imaging; * provide blood samples for determinaton of serological biomarkers auf dysautonomia.
Conditions
Timeline
- Start date
- 2025-04-01
- Primary completion
- 2026-02-01
- Completion
- 2026-05-01
- First posted
- 2024-12-18
- Last updated
- 2025-03-13
Source: ClinicalTrials.gov record NCT06740942. Inclusion in this directory is not an endorsement.