| Not Yet Recruiting | Regenerative Outcomes for Peri-implant Bony Defects Using Amnion-chorion Barrier vs. Collagen Membrane NCT07032259 | Loma Linda University | N/A |
| Not Yet Recruiting | Long-term Stability of Peri-implantitis Treatments: a 3-year Clinical Evaluation NCT07208643 | Ramón Pons Calabuig | — |
| Not Yet Recruiting | Crown Removal in Non-Surgical Peri-Implantitis Therapy: A Randomized Trial NCT07391202 | G. d'Annunzio University | N/A |
| Completed | The Effect of Systemic Factors on Peri-implant Health Status and Clinical Indices NCT07530211 | Inonu University | — |
| Recruiting | Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis NCT07471386 | Gazi University | N/A |
| Not Yet Recruiting | Comparison of Two Non-surgical Procedure to Manage Gum Disease Around Implants. NCT07365722 | King's College London | N/A |
| Recruiting | Immediate Versus Delayed Surgical Reconstruction of Peri-implantitis Intra-bony Defects. NCT07325747 | University of Michigan | N/A |
| Recruiting | Minimally-Invasive Non-Surgical Therapy of Peri-Implantitis NCT07466966 | St. Anne's University Hospital Brno, Czech Republic | N/A |
| Not Yet Recruiting | Evaluation of 25(OH)D3 and LL-37 Levels in Periimplant Sulcus Fluid NCT07280754 | Recep Tayyip Erdogan University | — |
| Not Yet Recruiting | Polynucleotide and Hyaluronic Acid-based Gel as Adjunctive Therapy to Non- Surgical Treatment of Intraosseous NCT06914518 | Universitat Internacional de Catalunya | N/A |
| Enrolling By Invitation | 20-25 Year Follow-Up on Regenerative Bone Procedures for Peri-Implantitis NCT06648564 | Kristianstad University | — |
| Recruiting | Natural Bioactive Gel for Peri-Implantitis NCT07088679 | University of Pavia | N/A |
| Recruiting | Immunological-Clinical Evaluation of the Etiopathogenesis of Peri-Implantitis NCT07012915 | Wroclaw Medical University | N/A |
| Recruiting | Efficacy of Photodynamic Therapy in the Non-Surgical Treatment of Peri-Implantitis NCT07191522 | Egas Moniz - Cooperativa de Ensino Superior, CRL | N/A |
| Completed | Microbiome Modulation by PEMF on Plaque Induced Mucositis in Human Jaws NCT07045636 | Jamil awad shibli | N/A |
| Recruiting | Peri-implantitis Treatment With Chitosan Brush NCT06830200 | Hacettepe University | N/A |
| Completed | Comparison of Two Interdental Devices for Peri-Implant Plaque Control NCT06923748 | University of Siena | N/A |
| Recruiting | Reconstructive Treatment of Peri-implantitis With Combined Defects NCT06957652 | Gazi University | N/A |
| Completed | Peri-implant Disease Perception Before and After Non-Surgical Peri-implant Therapy NCT06901388 | University of Siena | N/A |
| Recruiting | Surgical Treatment of Peri-implantitis With Adjunctive Application of Platelet Rich Fibrin (PRF) NCT06679283 | University of Bern | N/A |
| Completed | Non-Surgical Laser Treatment for Peri-Implantitis: Er:YAG & Diode Laser NCT06890117 | Aristotle University Of Thessaloniki | N/A |
| Not Yet Recruiting | SPIC Frequency After Surgical Treatment of Peri-implantitis NCT06762353 | University of Turin, Italy | N/A |
| Not Yet Recruiting | Non-Surgical Treatment of Peri-implantitis with Systemic Azithromycin or Placebo NCT06715150 | University of Santiago de Compostela | Phase 4 |
| Completed | Fully Guided Dental Implant Placement and Primary Stability NCT07149987 | University of Mosul | N/A |
| Completed | Collagen Membrane and Allograft in Peri-Implantitis Surgery NCT07478978 | Ondokuz Mayıs University | N/A |
| Recruiting | Evaluation of Fractalkine and Its Receptor in Peri-implantitis NCT06685523 | Kubilay BARIŞ | N/A |
| Not Yet Recruiting | Effect of Enamel Matrix Derivative or Hyaluronic Acid on Non-Surgical Treatment of Peri-Implantitis NCT06618560 | Gazi University | N/A |
| Not Yet Recruiting | Surgical Treatment of Peri-implantitis Defects NCT06614426 | Abeer Hakam | N/A |
| Completed | Effect of Emergence Angle on Peri-implant Status NCT07295743 | Abant Izzet Baysal University | — |
| Completed | Free Amino-acid Composition of Peri-implant and Periodontal Conditions NCT07187323 | Istanbul Medipol University Hospital | — |
| Recruiting | Transcriptome, Proteome and Microbiome Profile in Periodontal and Peri-implant Diseases NCT06262035 | Karolinska Institutet | — |
| Recruiting | The Adjunctive Effect of a Titanium Brush in the Non-Surgical Treatment of Peri-Implantitis NCT06843928 | Universitat Internacional de Catalunya | N/A |
| Enrolling By Invitation | Intaglio Surface of Full-arch Implant Supported Prosthesis NCT06636097 | University of Pittsburgh | — |
| Completed | Impact of an AI-Based Chatbot on Implant Patient Management: RCT NCT07300657 | University of Catania | N/A |
| Enrolling By Invitation | Efficacy of Non-surgical and Surgical Surface Decontamination Methods on Peri-implantitis-affected Implants NCT06430268 | Andrea Ravida | N/A |
| Recruiting | Antibacterial Photodynamic Therapy in the Management of Peri-implantitis NCT06017817 | Nilminie Rathnayake | N/A |
| Completed | Effect of Smoking on Macrophage-related Chemokines Before and After Non-surgical Treatment of Initial Peri-imp NCT06810401 | Buse Naz BÜYÜKAKÇALI ALTAY | N/A |
| Completed | Patients' Illness Perception of Peri-implant Diseases. A Cross-sectional Study NCT06383351 | University of Siena | — |
| Recruiting | Distance Between Dental Implants as a Risk Indicator for Peri-implant Disease. NCT06364982 | Universitat Internacional de Catalunya | — |
| Unknown | Laterally Rotated Flap for Soft Tissue Augmentation Around Maxillary Loaded Osseointegrated Dental Implant NCT06206499 | Universidad de Murcia | N/A |
| Unknown | Lingual Keratinized Tissue in Fully Edentulous Patients and Its Impact on Implant Health NCT06166017 | George Eastman Dental Hospital, Italy | — |
| Completed | Treatment of Peri-implant Bone Dehiscence Using Autogenous Tooth Plate NCT06313216 | Kafrelsheikh University | N/A |
| Active Not Recruiting | Erythritol vs Ultrasonic Scaler Prophylaxis Systems on Dental Implants With Crowns Made by Different Materials NCT06288919 | University of Pavia | N/A |
| Unknown | Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical NCT06287957 | Istanbul University | N/A |
| Recruiting | Adjunctive Use of Dermal Matrix to Compensate Dimensional Changes in the Reconstructive Therapy of Peri-implan NCT06398288 | Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain | N/A |
| Unknown | Prevalence and Risk Indicators of Peri-implant Diseases in China NCT06208254 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | — |
| Recruiting | The Study on the Accuracy of Peri-implant Probing and Related Influencing Factors NCT07004517 | The Dental Hospital of Zhejiang University School of Medicine | — |
| Recruiting | Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip NCT06514677 | Kutahya Health Sciences University | N/A |
| Completed | Ridge Splitting With Implant Placement Using Autogenous Tooth Graft NCT06131541 | Kafrelsheikh University | N/A |
| Enrolling By Invitation | Regenerative Treatment of Peri-implantitis NCT06153212 | University of Michigan | N/A |
| Completed | Clinical Efficacy of Hybenix vs Chlosite Gels in Peri-implantitis NCT06083246 | University of Pavia | N/A |
| Completed | In Vivo Biofilm Accumulation on Implants With 3 Different Surfaces NCT06049121 | Malmö University | — |
| Enrolling By Invitation | Incidence of Bleeding on Probing as an Indicator of Peri-Implant Disease Progression NCT06033859 | University of Pittsburgh | — |
| Enrolling By Invitation | Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplas NCT06063876 | University of Pittsburgh | N/A |
| Completed | Long-term Outcomes of Implants in Patients with Periodontitis NCT06852599 | Heidelberg University | — |
| Recruiting | Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry NCT06554041 | Harvard Medical School (HMS and HSDM) | N/A |
| Completed | Efficacy of Er: YSGG Laser in Treatment of Peri-implantitis NCT05137821 | Ain Shams University | N/A |
| Recruiting | Management of Peri-implantitis: Non-surgical Treatment of Peri-implantitis. NCT05683405 | Tannhelsetjenestens Kompetansesenter for Nord-Norge | N/A |
| Recruiting | Comparison of the Effectiveness of Two Different Surgical Therapeutic Protocols of Peri-implantitis NCT05899933 | National and Kapodistrian University of Athens | N/A |
| Completed | Compliance and Cumulative Interceptive Rate After Therapy of Peri-implantitis NCT05772078 | Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain | — |
| Unknown | "Association of Peri-implantitis and Maxillary Sinusitis: a Case-control Study". NCT05924711 | Universitat Internacional de Catalunya | — |
| Completed | Elucidating the Role of STAT3 in Epithelial-microbiome Interaction During Periodontitis and Peri-implantitis NCT07055256 | University of Chile | — |
| Unknown | Efficacy of Air-polishing on Pain Perception and Compliance Rate NCT06109701 | Universitat Internacional de Catalunya | N/A |
| Enrolling By Invitation | Comparison of Dental Implants with Different Surface Properties NCT06508723 | Kutahya Health Sciences University | N/A |
| Completed | Investigation Of Marginal Bone Loss In Implants With Different Surface Properties And Geometric Designs: A Ret NCT06148012 | Recep Tayyip Erdogan University | N/A |
| Completed | Peri-implantitis and MMP-8 NCT05711407 | Aristotle University Of Thessaloniki | — |
| Completed | Peri-Implant Sulcus Fluid Stress Markers in Health and Disease NCT07353515 | Inonu University | — |
| Recruiting | Periodontitis and Inflammation NCT04831060 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | The Role of Obesity in Peri-Implant Health(ROPIPH) NCT07183163 | Mine Keskin | — |
| Completed | Decontamination Methods in the Treatment of Peri-implantitis NCT07500844 | Research Centre for Medical Genetics, Russian Federation | N/A |
| Enrolling By Invitation | Surgical Treatment of Peri-implantitis Using a Bone Substitute With or Without a Resorbable Collagen Membrane NCT05699343 | Andrea Ravida | N/A |
| Completed | Prevention of Dental Implant Diseases NCT05871229 | Hanna Lähteenmäki | N/A |
| Completed | Implant-supported Fixed Dental Prostheses (FDPs) With Cantilever Extension NCT05676268 | University of Bern | — |
| Unknown | SPiT-frequency; the Effect of Increased Frequency of Intervention on Post-surgical Peri-implant Inflammation NCT04705012 | University of Oslo | N/A |
| Recruiting | Immediate Versus Delayed Loading of Single Posterior Zirconia Implants NCT05838365 | University of Milan | Phase 4 |
| Unknown | Citric Acid Passivation on Implant Abutments for the Prevention of Peri-implant Disease NCT05592327 | Universitat Internacional de Catalunya | N/A |
| Recruiting | The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis NCT05415111 | Nadja Naenni | N/A |
| Unknown | Non-surgical Electrolytic Cleaning Peri-implantitis NCT05275894 | Universidad Complutense de Madrid | N/A |
| Unknown | Adjunctive Benefit of Electrolytic Cleaning on Non-surgical Treatment of Peri-implantitis. NCT05179746 | University of Lisbon | N/A |
| Unknown | Characterizing the Inflammation Around Dental Implants NCT05675241 | McGill University | — |
| Completed | Reconstructive Therapy of Peri-implantitis with PDGF-BB (Gem-21) NCT06390124 | Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain | Phase 4 |
| Recruiting | Expression of Epithelial-Mesenchymal Transition Associated Markers in Peri-implant Tissues NCT05832541 | University of Baghdad | — |
| Recruiting | Antiseptic Effects on the Dental Implant Internal Surface Microbiome NCT05024760 | Madigan Army Medical Center | EARLY_Phase 1 |
| Completed | Analysis of the Factors Influencing the Occurrence of Peri-implant Inflammation in Patients With Oral Implant NCT06998160 | Hui Xie | N/A |
| Completed | Peri-implant Conditions Mimic Periodontal Conditions NCT06128850 | Abant Izzet Baysal University | — |
| Completed | All on Six Versus Parallel Implant Distribution for Maxillary Denture Opposing Mandibular All on Four NCT05960500 | Mansoura University | N/A |
| Unknown | MicroRNAs and Cytokines in Peri-Implantitis Tissue NCT05765942 | University of Baghdad | — |
| Completed | (PEKK) Framework for Mandibular Implant-supported Complete Fixed Prostheses NCT06164990 | Fatma mahanna | N/A |
| Unknown | The Influence of Implant Position on the Occurrence of Biological Complications NCT05358782 | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | — |
| Completed | "Surgical Vs. Non-surgical Peri-implant Therapy" NCT05168891 | Universitat Internacional de Catalunya | N/A |
| Recruiting | Investigation of Biofilm Formation on Temporary push-on Rings of Implant Crowns NCT05122897 | University Hospital, Basel, Switzerland | N/A |
| Active Not Recruiting | Influence of Implant Surface Decontamination on the Reconstructive Outcomes of Peri-implantitis NCT05615051 | Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain | N/A |
| Completed | Monitoring of Non-Surgical Treatment of Peri-implantitis NCT06408467 | Lahanna oy | N/A |
| Completed | Vitamin-D Insufficiency and Implants NCT06452251 | Vesile Elif Toy | — |
| Completed | Non-surgical Treatment of Peri-implantitis With and Without Erythritol Air-polishing NCT04152668 | Knut N. Leknes | N/A |
| Unknown | Implantoplasty as Adjunct to Combined Surgical Therapy of Peri-Implantitis NCT06131567 | Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain | N/A |
| Enrolling By Invitation | Air-polishing in the Treatment of Peri-implantitis NCT04847648 | Göteborg University | N/A |
| Unknown | 20-year Implant Survival in Periodontally Healthy and Compromised Patients NCT04983758 | University of Turin, Italy | — |
| Completed | HIF-1 Alpha, VEGF and MMP-8 Levels in PICF of Smokers Versus Non Smokers NCT05325918 | Future University in Egypt | — |
| Completed | Health of Peri-implant Tissues Adjacent to Zirconia NCT05081076 | Pontificia Universidade Católica do Rio Grande do Sul | N/A |
| Unknown | Increased Peri-implant Keratinized Mucosal Thickness at Different Operative Times NCT04683991 | Second Affiliated Hospital, School of Medicine, Zhejiang University | N/A |
| Completed | Lasers in Peri-implantitis Treatment NCT05733234 | Aristotle University Of Thessaloniki | N/A |
| Unknown | Evaluation of the Novel Implant Disease Risk Assessment : a Retrospective Study (IDRA) NCT04888572 | Saint-Joseph University | — |
| Recruiting | Lnfluence of the Prosthetic Emergence Profile on the Prevalence of Peri-implant Diseases NCT05592314 | Ramón Pons Calabuig | — |
| Completed | Expression of Inflammasomes in Peri-implantitis and Periodontitis NCT05061511 | University of Parma | — |
| Completed | Surgical Access Combined With Systematically Administered Antibiotics in the Treatment of Peri-implantitis NCT05444218 | University of Guarulhos | N/A |
| Unknown | Use of Various Laser Systems in Peri-implatit NCT04826783 | Kırıkkale University | N/A |
| Unknown | Peri-implantitis Surgical Regenerative Therapy Using Bovine Bone Substitute With Hyaluronic Acid NCT05171582 | Botiss Medical AG | N/A |
| Unknown | Analysis of Genetic Variations in Patients With Peri-implantitis NCT04807725 | Egas Moniz - Cooperativa de Ensino Superior, CRL | — |
| Unknown | Biological Responses Affecting Early-stage Dental Implant Placement in Patients With History of Periodontitis NCT05834946 | University of Malaya | N/A |
| Completed | Macrophage Markers in Periodontal and Peri-implant Health and Disease NCT05242354 | Biruni University | — |
| Completed | Correlation Between Peri-implantitis and Assumptions of Medications NCT04783974 | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | — |
| Completed | Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study NCT04952428 | Universitat Internacional de Catalunya | — |
| Completed | Outcome Indicators of Non-surgical Therapy of Peri-implantitis NCT05539755 | Universitat Internacional de Catalunya | N/A |
| Completed | Evaluation of the Patient's Risk Profile Using the Peri-implantitis Risk Diagram NCT05618171 | Berceste Guler | — |
| Completed | Epstein-Barr Virus Implication in Peri-implantitis: Towards an Innovative Etiopathogenic Model. NCT03631849 | Centre Hospitalier Universitaire de Nice | N/A |
| Completed | Radiological Bone Loss on Different Levels of Dental Implants NCT05595746 | Kutahya Health Sciences University | N/A |
| Recruiting | Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects Wit NCT05906810 | University of Catania | N/A |
| Unknown | Soft Tissue Assessment in Screw-Retained Maxillary Complete Denture With Electric Welded Framework Versus Cast NCT04543864 | Cairo University | N/A |
| Completed | ICG-PDT, Periimplantitis, Diabetes Mellitus NCT04833569 | King Saud University | Phase 1 |
| Unknown | Resective Surgical Treatment of Peri-implantitis. NCT04337645 | University of Belgrade | N/A |
| Completed | Comparison of the Accuracy of Different Periodontal Probes for Peri-implant Pocket Registration NCT05332327 | Malmö University | — |
| Completed | Reconstructive Surgical Therapy of Peri-implantitis NCT04769609 | Gazi University | — |
| Completed | Influence of Keratinized Mucosa on Dental Implants With Mucositis NCT04874467 | Universitat Internacional de Catalunya | N/A |
| Unknown | Treatment of Peri-implantitis With or Without Simultaneous Soft Tissue Augmentation NCT04323540 | George Eastman Dental Hospital, Italy | N/A |
| Recruiting | Long-term Surgical Treatment Outcome of Peri-implantitis Lesions NCT05339789 | Malmö University | — |
| Completed | Peri-implant Phenotype, Calprotectin and Mmp-8 Levels in Cases Diagnosed With Peri-implant Disease NCT06173739 | Beliz Önder | N/A |
| Completed | Alveolar Ridge Sequelae Due to Peri-implantitis: a Retrospective Observational Study NCT04534361 | Universitat Internacional de Catalunya | — |
| Completed | Reconstructive Therapy for Peri-implantitis Using Tuberosity Bone with or Without Electrolytic Cleaning: a Ran NCT06708247 | Vilniaus Implantologijos Centro (VIC) Klinika | N/A |
| Completed | Peri-implantitis in HIV-positive Patients With Different Dental Prosthesis NCT04983212 | Università Vita-Salute San Raffaele | — |
| Completed | Evaluate the Influence of Electromagnetic Field as an Adjunctive Non Surgical Treatment in Implant With Peri-i NCT04213144 | Rambam Health Care Campus | N/A |
| Completed | Predictive Value of Reduced Keratinized Mucosa on the Secondary Prevention of Peri-implant Mucositis and Perii NCT05804760 | Hannover Medical School | — |
| Completed | Er,Cr:YSGG Laser Application in Peri-implantitis NCT06031467 | Yuzuncu Yil University | N/A |
| Completed | Maxillary Sinus Floor Augmentation With Different Grafting Materials NCT04749953 | Aalborg University Hospital | N/A |
| Unknown | Assessment of Efficacy of Calprotectin and Cross-linked N-telopeptides NCT04177732 | Mansour Assery | N/A |
| Terminated | Clinical Outcomes of Resective Surgical Treatment of Peri-Implantitis With or Without Implantoplasty NCT04259840 | University of Michigan | — |
| Completed | Non-surgical Mechanical Therapy of Peri-implantitis With or Without Adjunctive Diode Laser Application NCT04565886 | University of Bern | N/A |
| Recruiting | Peri-implantitis Implantoplasty Treatment NCT04052373 | University of Oslo | N/A |
| Completed | Peri-implantitis, Comparing Treatments 970 nm Laser and Mucosal Flap Surgery NCT04249024 | Karolinska Institutet | N/A |
| Completed | Non-invasive Solution for Periodontal and Peri-implant Diseases (INPERIO) NCT03977714 | Nanoker Research S.L. | N/A |
| Completed | Therapeutic Peri-implant Maintenance with Laser Therapy NCT04251793 | University of Michigan | — |
| Withdrawn | Surface Decontamination in Treatment of Peri-Implantitis NCT03114956 | University of Southern California | N/A |
| Withdrawn | Establishing a New Protocol for Early Mucositis and Peri-implantitis Treatment Using an Air-polishing Device NCT03348111 | University Hospital, Toulouse | N/A |
| Unknown | Metabolomic and Proteomic Fingerprinting in Peri-implant Diseases NCT04283903 | Universidad Complutense de Madrid | — |
| Unknown | Guided Bone Regeneration of Peri-implant Defects Comparing Submerged Versus Non-submerged Healing NCT03900741 | Ana Molina Villar | N/A |
| Completed | New Periodontal Classification NCT04271787 | Beni-Suef University | — |
| Completed | Histological, Genetic and Epigenetic Analysis of Procedures Related with Dental Implants NCT04421066 | Simón Pardiñas López | — |
| Completed | Er,Cr:YSGG and Diode Lasers in the Treatment of Peri-implantitis NCT04730687 | Yuzuncu Yil University | N/A |
| Completed | Peri-implantitis Treatment: Clinical Results of Conventional Treatment vs. the Addition of Biolase NCT03544515 | Columbia University | N/A |
| Completed | The Cortical Shield for Facial Bone Reconstruction NCT04827693 | Verdugo, Fernando, DDS | — |
| Unknown | Antimicrobial Photodynamic Therapy Mediated by Papain Gel on Peri-Implantitis Lesions NCT03753958 | University of Nove de Julho | Phase 2 |
| Completed | Ten Years Follow up of Peri-implant Surgery NCT04254406 | Public Dental Service, Specialist Clinics, Sweden | — |
| Completed | Prediction of Failure of Dental Implants NCT04129957 | Academic Centre for Dentistry in Amsterdam | — |
| Terminated | Long-term Surgical Therapeutic Outcomes of Peri-Implantitis NCT03772652 | University of Michigan | — |
| Completed | Proteomic Analysis of Newly Restored Single Implants NCT06379022 | Aristotle University Of Thessaloniki | — |
| Completed | Non Surgical Protocol for Treatment of Peri-implantitis NCT03451981 | Università Vita-Salute San Raffaele | N/A |
| Terminated | Efficacy of Synthetic Bone Graft for Treatment of Peri-implantitis NCT03213210 | Sunstar Americas | N/A |
| Unknown | Clinical and Biochemical Evaluation of the Efficacy of Non-Surgical Treatment Approaches in the Treatment of P NCT05201443 | Hacettepe University | N/A |
| Completed | Peri-implant Disease and Prosthetic Cement: Cross-sectional Study NCT05945836 | University of Bologna | — |
| Completed | The Role of Bleeding at Implant Placement NCT03705247 | Universitaire Ziekenhuizen KU Leuven | — |
| Withdrawn | Comparing Two Treatment Modalities of Peri-implantitis - Blue Laser (445 nm) and Conventional Flap Surgery NCT03624257 | Sirona Dental Systems GmbH | N/A |
| Completed | The Morphology of the Peri-Implantitis Defects: A Cone-Beam Computed Analysis NCT03777449 | Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain | — |
| Unknown | Surgical Protocol for Peri-Implantitis Treatment-3 NCT03977324 | Università Vita-Salute San Raffaele | N/A |
| Unknown | Surgical Protocol for Peri-implantitis Treatment-2 NCT03977285 | Università Vita-Salute San Raffaele | N/A |
| Unknown | Surgical Protocol for Peri-implantitis Treatment NCT03801187 | Università Vita-Salute San Raffaele | N/A |
| Unknown | Surgical Protocol for Peri-Implantitis Treatment-4 NCT03977298 | Università Vita-Salute San Raffaele | N/A |
| Completed | Surgical Treatment of Peri-implantitis With and Without an Initial Non-surgical Approach NCT03620331 | Universidad Complutense de Madrid | N/A |
| Completed | Comparison of CTG and T-PRF on Peri-Implant Soft Tissue NCT04042194 | Abant Izzet Baysal University | N/A |
| Unknown | Surgical Treatment of Periimplantitis in Patients With Risk Factors NCT03814434 | Luiz Antonio Pugliesi Alves de Lima | N/A |
| Unknown | Combined Er:YAG And Nd:YAG Laser Protocol For Treatment Of Peri-Implantitis NCT03819075 | Luis Monteiro | N/A |
| Completed | Metronidazole as an Adjunct of Non- Surgical Treatment of Peri-implantitis NCT03564301 | Juan Blanco Carrión | Phase 4 |
| Terminated | Assessment of the Accuracy of the Clinical Parameters & Radiographs in Determining the Topography of Implant B NCT03698851 | National Dental Centre, Singapore | N/A |
| Completed | Understanding, Modulation and Memorization of Indicators Associated to Peri-implantitis NCT04543604 | Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain | N/A |
| Completed | Microbiota Around Periodontal Teeth and Implants Affected by Peri-implant Disease. NCT03407911 | Azienda Ospedaliera, Universitaria Policlinico Vittorio Emanuele | — |
| Completed | Exploring the Relationship Among Dental Caries, Nutritional Habits and Peri-implantitis NCT04439877 | Universitat Internacional de Catalunya | — |
| Completed | Association of Keratinised Mucosa Around Implants and Teeth With Peri-implant/Periodontal Disease and Soft Tis NCT03501537 | Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain | N/A |
| Completed | Flapless Surgical Treatment of Peri-implantitis NCT06093360 | Universidad Complutense de Madrid | — |
| Completed | Dental Hygiene and Peri-Implant Tissues Homeostasis Ancillary Study NCT03917264 | University of Washington | N/A |
| Completed | Dental Hygiene and Peri-Implant Tissues Homeostasis NCT03384446 | University of Washington | N/A |
| Completed | Diode Laser for Treatment of Peri-implantitis NCT03383120 | University of Geneva, Switzerland | N/A |
| Completed | Regenerative Surgical Treatment of Peri-implantitis Using Nanobone With or Without Simvastatin NCT04559841 | Reham Lotfy Aggour | N/A |
| Completed | Early and Late Implant Failure NCT04270396 | Universitat Internacional de Catalunya | — |
| Completed | Treatment of Mild to Moderate Peri-implantitis Using an Oscillating Chitosan Device NCT03373448 | Labrida AS | N/A |
| Completed | Laser-Assisted Regenerative Surgical Therapy for Peri-implantitis NCT03127228 | University of Michigan | N/A |
| Completed | Surgical Treatment of Peri-implantitis NCT03163602 | The University of Western Australia | N/A |
| Completed | Anti-infective Effect of Non-surgical Treatment With and Without Photodynamic Therapy on Initial Peri-implanti NCT02848482 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | Phase 3 |
| Completed | Efficacy of Er:YAG Laser in Decontamination of Dental Implants: An In-Vitro Study NCT03100435 | Tufts University | N/A |
| Completed | Dental Implant Care and Oral Hygiene Practices NCT03497065 | National University Health System, Singapore | — |
| Active Not Recruiting | Peri-implantitis - Reconstructive Surgical Therapy NCT03077061 | Göteborg University | N/A |
| Unknown | Patient Perception and Clinical Efficacy of a Collagen Matrix for the Treatment of Peri-implantitis NCT03551145 | Universidad Complutense de Madrid | Phase 4 |
| Completed | Comparison of Short and Standard Dental Implants NCT04475406 | Alanya Alaaddin Keykubat University | N/A |
| Completed | Diagnostic and Prognostic Test for Periodontitis and Peri-implantitis (AHC-FRDgrant) NCT06784362 | University of Minnesota | — |
| Completed | The Effect of Different Dental Implant Surface Characteristics on Immunological and Microbiological Parameters NCT03693196 | Necmettin Erbakan University | N/A |
| Completed | An Evaluation of Salivary Oxidant and Antioxidant Levels in Peri-implant Health and Disease NCT05724706 | Biruni University | — |
| Completed | Sensitivity and Specificity of Peri-Implantitis-Related Parameters NCT03031392 | Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain | — |
| Completed | BonyPid-500TM Bone Graft Substitute Study NCT02531100 | PolyPid Ltd. | N/A |
| Withdrawn | Laser Therapy Treatment of Peri-implantitis. NCT01972399 | University of Michigan | Phase 3 |
| Completed | Long-term Follow-up Observation After Surgical Treatment of Peri-implantitis in Multicenter Post Market Clinic NCT03776097 | Geistlich Pharma AG | — |
| Completed | Development of a Molecular Diagnosing Platform for Relieving Periodontal Symptoms NCT03345329 | General Biologicals Corporation | — |
| Completed | The Use of a Probiotic Lozenge in the Treatment of Peri-implantitis NCT02520401 | Universitaire Ziekenhuizen KU Leuven | N/A |
| Completed | Locally Delivered 1% Metformin Gel in Peri-implantitis NCT03312582 | King Saud University | Phase 4 |
| Completed | Peri-implantitis in HIV-positive Patients NCT04829968 | Università Vita-Salute San Raffaele | — |
| Completed | Outcome After Dental Implant Treatment NCT02671812 | Folktandvården Stockholms län AB | — |
| Completed | Ozone Therapy as an Adjunct to the Surgical Treatment of Peri-implantitis NCT03018795 | Gazi University | N/A |
| Completed | Treatment of Peri-implantitis Lesions by Using Biomaterial NCT02375750 | Geistlich Pharma AG | N/A |
| Completed | Effect of Hyaluronic Acid on Perimplantitis NCT03157193 | Universidad de Granada | Phase 4 |
| Completed | The Efficacy and Safety of Chlorhexidine Gluconate Chip (PerioChip®) in Therapy of Peri-implantitis NCT02080403 | Dexcel Pharma Technologies Ltd. | Phase 3 |
| Completed | Surgical and Non-surgical Treatment of Peri-implantitis NCT02241577 | Federal University of Rio Grande do Sul | N/A |
| Unknown | a Randomized Clinical Trial Evaluating Plaque Removal Around Dental Implants NCT02091609 | University of Manitoba | N/A |
| Completed | COMPARISION OF DIFFERENT TREATMENT METHODS OF PERI-IMPLANTITIS NCT03241953 | Necmettin Erbakan University | N/A |
| Completed | Cellular and Molecular Inflammatory Mechanisms Leading to Bone Resorption in Peri-implantitis Vs Periodontitis NCT02664675 | University of Paris 5 - Rene Descartes | — |
| Completed | Effect of Probiotic Lactobacillus Reuteri in the Treatment of Mucositis and Periimplantitis NCT03047291 | Universitat Internacional de Catalunya | Phase 4 |
| Completed | Evaluation of Photodynamic Therapy in Treatment of Peri-implantitis NCT05187663 | University of Belgrade | N/A |
| Completed | Follow-Up After Surgical Treatment of Peri-implantitis NCT02860208 | Göteborg University | — |
| Completed | A NEW MECHANICAL DECONTAMINATION METHOD IN PERI-IMPLANTITIS, TI-BRUSH, A RANDOMIZED CONTROLLED CLINICAL TRIAL NCT03512730 | Universitat Internacional de Catalunya | Phase 2 |
| Completed | Assessment of the Effects of Different Implant Abutment Occluding Materials on Dental Implant Health Parameter NCT02625597 | Stony Brook University | N/A |
| Unknown | Peri-Implantitis Surgical Treatment an RCT Study NCT02575274 | Mr. Sergio Diniz Ferreira | Phase 2 / Phase 3 |
| Completed | Peri-implantitis Between Periodontitis and Nonperiodontitis Sites With ARP NCT05713682 | Kaohsiung Medical University Chung-Ho Memorial Hospital | — |
| Completed | Clinical and Radiographic Outcomes of Dental Implant Therapy NCT01825772 | Göteborg University | — |
| Completed | Effect of a Maintenance Protocol After Surgical Treatment of Peri-implantitis NCT05574218 | Universidad Complutense de Madrid | N/A |
| Completed | Surgical Treatment of Peri-implantitis NCT01857804 | Göteborg University | Phase 4 |
| Completed | Systemic Amoxicillin Plus Metronidazole in Peri-implantitis Treatment NCT04149327 | University Medical Center Groningen | Phase 4 |
| Unknown | The Use of Water Jet for Initial Treatment FOR Peri-Implant Disease NCT01509898 | Rambam Health Care Campus | N/A |
| Completed | The Effect of Obesity on Oral Peri-implant Health - A Cross-Sectional Study NCT01878071 | University of Iowa | — |
| Completed | Arestin - Use in Subjects With Peri-Implantitis (With Subgingival Microbiological Evaluation) NCT01517334 | OraPharma | Phase 3 |
| Completed | Arestin - Use in Subjects With Peri-Implantitis NCT01539564 | OraPharma | Phase 3 |
| Unknown | Therapy of Peri-implantitis: Scaling Versus Low Abrasive Powder NCT01256996 | Heidelberg University | Phase 2 |
| Completed | A Comparison of Inflammatory Mediators Surrounding Titanium or Zirconium Implant Abutments NCT01870349 | Christopher Barwacz | — |
| Completed | Triclosan Toothpaste in the Maintenance Phase of Peri-implantitis Treatment. NCT03191721 | University of Guarulhos | Phase 3 |
| Completed | Reconstruction of Peri-implant Osseous Defects: A Randomized Trial NCT02406001 | Tigran Technologies AB | N/A |
| Completed | Implant Surface Decontamination With 2 % Chlorhexidine in Peri-implantitis Treatment NCT01852253 | University Medical Center Groningen | N/A |
| Completed | The Efficacy and Safety of Chlorhexidine Gluconate Chip (Periochip®) in Therapy of Symptoms in Patients With P NCT01079663 | Dexcel Pharma Technologies Ltd. | Phase 2 |
| Completed | Efficacy of Diode Laser in Peri-implantitis NCT02362854 | Istanbul University | N/A |
| Completed | Implant Surface Decontamination in Peri-implantitis Treatment NCT01521260 | University Medical Center Groningen | N/A |
| Completed | Regenerative Surgical Treatment of Peri-implantitis NCT02500654 | Catrine Isehed | Phase 4 |