NCT03705247

The Role of Bleeding at Implant Placement

The Role of Bleeding at Implant Placement: a Prospective Observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 102 (actual)
• Sponsor: Universitaire Ziekenhuizen KU Leuven · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Angiogenesis is inherently associated to bone formation and healing. During implant osseointegration, a successive and successful angiogenic processes has to occur to promote bone formation. In 1969, Branemark et al. demonstrated that direct contact between bone and titanium implant surface was possible, defining osseointegration as "the direct, structural, and functional contact between live bone and the surface of a functionally loaded implant". Consequently, the need of an empirical measurement appeared. With the introduction of resonance frequency analysis (RFA), it is now possible to measure the degree of implant stability at any time during the course of implant treatment and loading. In this way, changes in implant stability can be monitored over the time and it is likely possible to find implants at risk of failure before they become loose. The rationale of this study is to analyse how important a good vascularization is for the future bone formation around dental implants.

Conditions

• Bleeding
• Angiogenesis
• Peri-Implantitis

Timeline

• Start date: 2018-10-01
• Primary completion: 2020-10-01
• Completion: 2021-01-04
• First posted: 2018-10-15
• Last updated: 2023-03-31

Locations

1 site across 1 country: Belgium