NCT05838365

Immediate Versus Delayed Loading of Single Posterior Zirconia Implants

Immediate Versus Delayed Loading of Single Posterior Zirconia Implants: A Multicenter Randomized Controlled Clinical Trial

• Status: Recruiting
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 220 (estimated)
• Sponsor: University of Milan · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The main aim of the present study is to investigate implant success rate after 5 years of function of immediate (Test group; within 7 days of implant placement) versus delayed (Control group; 8 weeks after implant placement) loading of two-pieces zirconia implant, placed in pristine bone without bone regeneration. Implant success rate will be defined according to Buser's criteria. Secondary endpoints: Marginal bone level (MBL) evaluation by means of standardized radiographs; Clinical evaluation of biological (e.g. Plaque Index, PI; Probing Pocket Depth, PPD, Bleeding on Probing, BOP; suppuration upon probing/palpation) and prosthetic/technical complications; Clinical evaluation of soft tissue width, keratinized tissue, marginal and interproximal soft tissue recession; Patient reported outcome measures (PROMs) by questionnaire administration:

Conditions

• Dental Implant Failed
• Peri-implant Mucositis
• Peri-Implantitis

Interventions

Type	Name	Description
DEVICE	Zirconia implant	(Test group; within 7 days of implant placement) versus delayed (Control group; 8 weeks after implant placement)

Timeline

• Start date: 2022-12-01
• Primary completion: 2024-06-01
• Completion: 2029-06-01
• First posted: 2023-05-01
• Last updated: 2023-05-01

Locations

1 site across 1 country: Italy