| Completed | The Effect of Systemic Factors on Peri-implant Health Status and Clinical Indices NCT07530211 | Inonu University | — |
| Not Yet Recruiting | Clinical, Radiographic, and Digital Evaluation of the Effects of Autogenous Grafts on Peri-implant Mucosa NCT07330609 | Kutahya Health Sciences University | N/A |
| Not Yet Recruiting | Effectiveness of Interproximal Cleaning Devices for Biofilm Removal Around Posterior Single Implants With Peri NCT07393828 | Universitat Internacional de Catalunya | N/A |
| Not Yet Recruiting | Effect of Water Flossing on Gingival Inflammation Around Single Implants NCT07364916 | King Abdulaziz University | N/A |
| Not Yet Recruiting | Evaluation of 25(OH)D3 and LL-37 Levels in Periimplant Sulcus Fluid NCT07280754 | Recep Tayyip Erdogan University | — |
| Not Yet Recruiting | Effect of Probe Material on Peri-implant Probing NCT07304752 | University of Barcelona | N/A |
| Recruiting | AI-Assisted Colorimetric Diagnosis of Peri-Implant Mucosal Erythema NCT07349095 | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | N/A |
| Recruiting | Trehalose vs Glycine Air-Polishing in Peri-Implant Mucositis Treatment NCT07140146 | University of Pavia | N/A |
| Recruiting | Immediate Implant Placement With Different Materials of Customized Healing Abutment for Guiding Peri-implant S NCT06645444 | Cairo University | N/A |
| Recruiting | Efficacy of Adjunctive At-Home Photodynamic Therapy (aPDT) in the Treatment of Peri-Implant Mucositis NCT06859866 | Koite Health Oy | N/A |
| Completed | Comparison of Two Interdental Devices for Peri-Implant Plaque Control NCT06923748 | University of Siena | N/A |
| Completed | Peri-implant Disease Perception Before and After Non-Surgical Peri-implant Therapy NCT06901388 | University of Siena | N/A |
| Recruiting | Efficacy of a Xanthan-based Chlorhexidine Gel in the Treatment of Peri-implant Mucositis NCT07047261 | University of Turin, Italy | N/A |
| Enrolling By Invitation | Effects of Enamel Matrix Derivative in the Treatment of Peri-implant Mucositis NCT06725095 | University of Catania | N/A |
| Completed | Periodontal Effects of Orthodontic Mini-Screws NCT07052747 | Dr. Mehmet Selim Yildiz | — |
| Completed | Impact of Oral Hygiene Instructions in the Resolution of Peri-implant Mucositis NCT06535958 | Universitat Internacional de Catalunya | N/A |
| Completed | Effect of Emergence Angle on Peri-implant Status NCT07295743 | Abant Izzet Baysal University | — |
| Completed | Free Amino-acid Composition of Peri-implant and Periodontal Conditions NCT07187323 | Istanbul Medipol University Hospital | — |
| Completed | Impact of an AI-Based Chatbot on Implant Patient Management: RCT NCT07300657 | University of Catania | N/A |
| Completed | Patients' Illness Perception of Peri-implant Diseases. A Cross-sectional Study NCT06383351 | University of Siena | — |
| Recruiting | Distance Between Dental Implants as a Risk Indicator for Peri-implant Disease. NCT06364982 | Universitat Internacional de Catalunya | — |
| Unknown | Lingual Keratinized Tissue in Fully Edentulous Patients and Its Impact on Implant Health NCT06166017 | George Eastman Dental Hospital, Italy | — |
| Recruiting | Impact of Keratinized Mucosa Augmentation on Treatment Outcomes of Peri-implant Mucositis NCT06305000 | Biruni University | N/A |
| Recruiting | Erythritol Air Polishing in Mucositis Treatment NCT06455306 | University of Coimbra | N/A |
| Active Not Recruiting | Erythritol vs Ultrasonic Scaler Prophylaxis Systems on Dental Implants With Crowns Made by Different Materials NCT06288919 | University of Pavia | N/A |
| Unknown | Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical NCT06287957 | Istanbul University | N/A |
| Completed | Treatment of Peri-implant Mucositis and Supportive Peri-implant Therapy NCT06137846 | University of Michigan | N/A |
| Not Yet Recruiting | Salivary Minerals in Patients With Peri-implantitis NCT05897736 | University of Zagreb | — |
| Enrolling By Invitation | Experimental Peri-implant Mucositis on Implant Sites That Were Previously Treated With or Without Implantoplas NCT06063876 | University of Pittsburgh | N/A |
| Completed | Long-term Outcomes of Implants in Patients with Periodontitis NCT06852599 | Heidelberg University | — |
| Recruiting | Soft Tissue Response to Different Restorative Materials Used in Implant Dentistry NCT06554041 | Harvard Medical School (HMS and HSDM) | N/A |
| Unknown | Treatment of Peri-implant Mucositis by Application of a Spermidine-based Gel NCT05926557 | Federico II University | N/A |
| Completed | Treatment of Peri-implant Mucositis by Sodium Hypochlorite Gel and Cross-linked Hyaluronic Acid Gel NCT05926297 | Federico II University | N/A |
| Unknown | Efficacy of Air-polishing on Pain Perception and Compliance Rate NCT06109701 | Universitat Internacional de Catalunya | N/A |
| Completed | Gels to Treat and Prevent Gingival Inflammation Around Dental Implants NCT06915623 | Nancy Mouradian | EARLY_Phase 1 |
| Completed | Effect of Free Gingival Grafting on Peri-implant Health NCT06392256 | Gazi University | N/A |
| Completed | Ultrasonic Scaler VS Erythritol for Peri-implant Maintenance of Loaded Implants With Crowns Made by Different NCT06496594 | University of Pavia | N/A |
| Completed | Non-surgical Mechanical Debridement With or Without Full-mouth Disinfection in the Treatment of Peri-implant M NCT05711576 | University of Catania | N/A |
| Completed | Mechanical Treatment Peri-Implant Mucositis NCT05664425 | University of Oslo | N/A |
| Completed | Peri-Implant Sulcus Fluid Stress Markers in Health and Disease NCT07353515 | Inonu University | — |
| Recruiting | Immediate Versus Delayed Loading of Single Posterior Zirconia Implants NCT05838365 | University of Milan | Phase 4 |
| Unknown | Characterizing the Inflammation Around Dental Implants NCT05675241 | McGill University | — |
| Recruiting | Antiseptic Effects on the Dental Implant Internal Surface Microbiome NCT05024760 | Madigan Army Medical Center | EARLY_Phase 1 |
| Completed | Peri-implant Conditions Mimic Periodontal Conditions NCT06128850 | Abant Izzet Baysal University | — |
| Completed | Domiciliary Use of Hyaluronic Acid Gel Solutions vs Domiciliary Use of Chlorhexidine Mouthwash 0,20% for the M NCT05312593 | University of Pavia | N/A |
| Completed | Ozoral Pro and Ozoral Gel vs Chlorhexidine Gel 1% for the Management of Peri-implant Mucositis Sites. NCT05254275 | University of Pavia | N/A |
| Completed | Xenogenic Collagen Matrix vs. Connective Tissue Graft for Soft Tissue Augmentation Around Early Maxillary Impl NCT07024186 | Minia University | N/A |
| Completed | Ozonized In-office and Domiciliary Gels vs Chlorhexidine Gel 1% for the Management of Peri-implant Mucositis S NCT05256914 | University of Pavia | N/A |
| Recruiting | Incidence of Peri-implant Mucositis in Patients With Treated Periodontitis NCT05356806 | Universidad Complutense de Madrid | — |
| Completed | Limosilactobacillus Reuteri as an Adjuvant in the Treatment of Peri-implant Mucositis NCT05758103 | Malo Clinic | N/A |
| Completed | Monitoring of Non-Surgical Treatment of Peri-implantitis NCT06408467 | Lahanna oy | N/A |
| Completed | Treatment of Inflammation Around Implants With a Laser or an Ultrasonic Device NCT05772299 | Kristianstad University | N/A |
| Completed | Evaluation of Soft Tissue Response to Titanium Healing Abutments Treated by Erbium: YAG Laser or Plasma Spray NCT05800795 | Ain Shams University | N/A |
| Completed | Chlorhexidine Gel and Peribioma Periogel Use in Peri-implant Mucositis Sites: a Split-mouth Randomized Clinica NCT04899986 | University of Pavia | N/A |
| Completed | Management of Peri-implant Mucositis With Ozone Water Jet: a Randomized Clinical Trial. NCT04845087 | University of Pavia | N/A |
| Unknown | Biological Responses Affecting Early-stage Dental Implant Placement in Patients With History of Periodontitis NCT05834946 | University of Malaya | N/A |
| Completed | Evaluation of Peri-implant Conditions of Orthodontic Mini Implants NCT06491849 | Dr. Mehmet Selim Yildiz | — |
| Completed | Association Between Smoking Habit and Peri-implant Diseases: a Case Control Study NCT04952428 | Universitat Internacional de Catalunya | — |
| Completed | Non Surgical Peri-implant Mucositis Treatment in Patients With Tissue-level and Bone-level Implants NCT04751565 | University of Messina | N/A |
| Completed | Evaluation of the Patient's Risk Profile Using the Peri-implantitis Risk Diagram NCT05618171 | Berceste Guler | — |
| Recruiting | Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects Wit NCT05906810 | University of Catania | N/A |
| Completed | Comparison of the Accuracy of Different Periodontal Probes for Peri-implant Pocket Registration NCT05332327 | Malmö University | — |
| Completed | Influence of Keratinized Mucosa on Dental Implants With Mucositis NCT04874467 | Universitat Internacional de Catalunya | N/A |
| Completed | Peri-implant Phenotype, Calprotectin and Mmp-8 Levels in Cases Diagnosed With Peri-implant Disease NCT06173739 | Beliz Önder | N/A |
| Unknown | Effect of Repeated Removal and Re-placement of Abutments Around Dental Implants NCT04415801 | University of Roma La Sapienza | N/A |
| Completed | Soft and Hard Tissues Evaluation Around Immediately Placed New Implant Design NCT04905758 | Kafrelsheikh University | N/A |
| Completed | Non-surgical Treatment of Peri-implant Mucositis: FMUD vs FMUD and Air-Flow Master Piezon® NCT05801315 | University of Siena | N/A |
| Completed | Predictive Value of Reduced Keratinized Mucosa on the Secondary Prevention of Peri-implant Mucositis and Perii NCT05804760 | Hannover Medical School | — |
| Recruiting | Peri-implantitis Implantoplasty Treatment NCT04052373 | University of Oslo | N/A |
| Completed | Non Surgical Protocol for Treatment of Mucositis NCT03951636 | Università Vita-Salute San Raffaele | N/A |
| Completed | Bacterial Microbiota Characterization on Implant-supported PEEK and Titanium Provisional Abutments NCT03998865 | Michael Wendler Ernst | N/A |
| Unknown | Metabolomic and Proteomic Fingerprinting in Peri-implant Diseases NCT04283903 | Universidad Complutense de Madrid | — |
| Completed | Non-surgical Treatment of Peri-implant Mucositis NCT03915665 | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | N/A |
| Completed | Influence of Soft Tissue Thickness Upon Dental Implant Esthetics NCT04805138 | Universitat Internacional de Catalunya | — |
| Completed | Histological, Genetic and Epigenetic Analysis of Procedures Related with Dental Implants NCT04421066 | Simón Pardiñas López | — |
| Terminated | Efficacy of an Oral Hygiene Implant Protocol NCT04462341 | Water Pik, Inc. | N/A |
| Completed | Proteomic Analysis of Newly Restored Single Implants NCT06379022 | Aristotle University Of Thessaloniki | — |
| Completed | Peri-implant Disease and Prosthetic Cement: Cross-sectional Study NCT05945836 | University of Bologna | — |
| Completed | A Topical Desiccant Agent in Association With Manual Debridement in the Treatment of Peri-implant Mucositis NCT03858959 | Universita di Verona | N/A |
| Completed | Comparison of CTG and T-PRF on Peri-Implant Soft Tissue NCT04042194 | Abant Izzet Baysal University | N/A |
| Completed | Propolis Extract, Nanovitamin C and Nanovitamin E in Peri-implant Mucositis NCT04215432 | Universidad Complutense de Madrid | N/A |
| Completed | The Efficacy of Stabilized Chlorine Dioxide Rinse as a Chemical Adjuvant for Treatment of Per-implant Mucositi NCT04838054 | Rowpar Pharmaceuticals, Inc. | Phase 4 |
| Unknown | Microbiome Shift in Peri-mucositis by Anti-inflammatory Drugs NCT03090009 | Polak David | EARLY_Phase 1 |
| Completed | Dental Implant Care and Oral Hygiene Practices NCT03497065 | National University Health System, Singapore | — |
| Unknown | Treatment of Peri-implant Mucositis by Means of Implant Decontamination and Modification of the Implant Suppor NCT03540290 | Universitat Internacional de Catalunya | N/A |
| Completed | Comparison of Short and Standard Dental Implants NCT04475406 | Alanya Alaaddin Keykubat University | N/A |
| Completed | The Effect of Different Dental Implant Surface Characteristics on Immunological and Microbiological Parameters NCT03693196 | Necmettin Erbakan University | N/A |
| Completed | Sensitivity and Specificity of Peri-Implantitis-Related Parameters NCT03031392 | Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain | — |
| Completed | Impact of Glycine Therapy on Peri-implant Mucositis NCT05810558 | Ohio State University | N/A |
| Completed | Effects of a 0.03% CHX Mouth Rinse in Peri-implant Mucositis NCT03533166 | Universidad Complutense de Madrid | N/A |
| Completed | Use of Topical Subgingival Application of Simvastatin Gel in the Treatment of Peri-Implant Mucositis NCT03400475 | Ahmed Mohamed Mahrous | Phase 2 |
| Completed | Impacts of Oral Irrigation in Patients With Periimplant Mucositis NCT03844035 | Ondokuz Mayıs University | N/A |
| Completed | The Effect of Peri-implant Surgery and Chair-side Supportive Post Surgical Peri-implant Therapy NCT03421717 | University of Oslo | N/A |
| Completed | Experimental Peri-implant Mucositis in Humans NCT01941797 | UConn Health | N/A |