NCT03533166

Effects of a 0.03% CHX Mouth Rinse in Peri-implant Mucositis

Clinical and Microbiological Effects of a 0.03% Chlorhexidine Mouth Rinse in the Prevention of Peri-implant Diseases: a Randomized Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 54 (actual)
• Sponsor: Universidad Complutense de Madrid · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Aim: To evaluate the efficacy of a 0.03% chlorhexidine (CHX) and 0.05% cetyl pyridinium chloride (CPC) mouth rinse, as an adjunct to professionally and patient-administered mechanical plaque removal, in the treatment of peri-implant mucositis. Material and Methods: Patients displaying peri-implant mucositis in, at least, one implant were included in this randomized, double-blinded, clinical trial. Subjects received a conventional professional prophylaxis (at baseline and 6-month visits) and were instructed to regular oral hygiene practices and to rinse, twice daily, during one year, with a 0.03% CHX and 0.05% CPC mouth rinse, or a placebo. Clinical, radiographic and microbiological data were recorded at baseline, 6 and 12 months. Disease resolution was defined as the absence of bleeding on probing (BOP). Repeated measures ANOVA, Student-t and chi square tests were used.

Conditions

• Peri-implant Mucositis

Interventions

Type	Name	Description
OTHER	Chlorhexidine	0.03% Chlorhexidine + 0.05% CPC mouth rinse
OTHER	Placebo	Placebo mouth rinse

Timeline

• Start date: 2015-11-04
• Primary completion: 2017-03-25
• Completion: 2017-04-07
• First posted: 2018-05-23
• Last updated: 2018-05-23

Locations

1 site across 1 country: Spain