NCT03345329

Development of a Molecular Diagnosing Platform for Relieving Periodontal Symptoms

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: General Biologicals Corporation · Industry
• Sex: All
• Age: 25 Years
• Healthy volunteers: Accepted

Summary

More than ninety percent of adults in Taiwan are suspected to carry periodontal disease, which causes bad breath, swollen and bleeding gums, plaque and even tooth loss. Half of the patients, however, are ignorance these clinical syndromes because of no obvious pain. In this study, the investigators selected six periodontal disease-associated bacteria strains, including Porphyromonas gingivalis (Pg), Fusobacterium nucleatum (Fn), Actinobacillus actinomycetemcomitans (Aa), Tannerella forsythia (Tf), Treponema denticola (Td) and Prevotella intermedia (Pi) as diagnostic markers. Using real-time PCR and MALDI Biotyper, the investigators will establish the database of oral microorganisms in Taiwanese people, providing periodontal disease clinical markers of high-risk groups and the basis for personal medicine of therapy in the future.

Conditions

• Periodontal Diseases
• Peri-Implantitis

Timeline

• Start date: 2015-10-01
• Primary completion: 2016-03-30
• Completion: 2016-09-30
• First posted: 2017-11-17
• Last updated: 2017-11-17