| Not Yet Recruiting | The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Amo NCT06746727 | VA Office of Research and Development | N/A |
| Not Yet Recruiting | Walk With Me (WWM) for Perinatal Grief NCT07011940 | Oregon Research Behavioral Intervention Strategies, Inc. | N/A |
| Not Yet Recruiting | Mindfulness-based Psilocybin Therapy for PTSD NCT07104916 | Anthony P King | Phase 2 |
| Not Yet Recruiting | Sensory Motor Arousal Regulation Treatment (SMART) Study NCT06035809 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Not Yet Recruiting | MDMA-Assisted Therapy for Veterans With PTSD and Alcohol Use Disorder NCT07118839 | VA Office of Research and Development | Phase 2 / Phase 3 |
| Recruiting | MDMA-Assisted Massed Exposure Therapy for PTSD NCT07288151 | Emory University | Phase 2 |
| Not Yet Recruiting | Recovering Sleep After Trauma NCT07196332 | University of North Carolina, Chapel Hill | N/A |
| Not Yet Recruiting | MDMA-Assisted Therapy for Stress Disorders in Healthcare Workers NCT05455996 | Nautilus Sanctuary | Phase 2 |
| Recruiting | Stepped Care for Posttraumatic Stress Disorder Study NCT06947538 | Boston Medical Center | N/A |
| Recruiting | Non-Trauma Intervention to Treat PTSD for Veterans and Service Members Suffering From a TBI NCT07351305 | The University of Texas Health Science Center at San Antonio | N/A |
| Recruiting | Non-invasive Vagus Nerve Stimulation (nVNS) for Post-Traumatic Stress Disorder (PTSD) NCT07523685 | Acacia Clinics | N/A |
| Not Yet Recruiting | Wayne State Warriors Marijuana Clinical Research Program: Cannabinoid Adjunct to Prolonged Exposure & Recovery NCT06222268 | Wayne State University | Phase 1 |
| Recruiting | An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1) NCT07456696 | Transcend Therapeutics | Phase 3 |
| Not Yet Recruiting | Psilocybin-Assisted Cognitive Processing Therapy for Chronic PTSD NCT06386003 | Unity Health Toronto | Phase 2 |
| Recruiting | BXCL501 After Stress to Increase Recovery Success NCT06943404 | University of North Carolina, Chapel Hill | Phase 2 |
| Recruiting | Nitric Oxide (NO) and Endothelial Dysfunction in Women With PTSD NCT07485231 | University of Minnesota | N/A |
| Not Yet Recruiting | Effect of Aquatic Therapy and Subsequent Training on Veterans With PTSD NCT07377214 | AquaTerapi | N/A |
| Recruiting | Building Ukraine's Strength in PTSD Treatment and Research NCT07318181 | University of Luxembourg | N/A |
| Recruiting | Determining the Potential for Efficacy of OTX-601 in Reducing PTSD Symptoms NCT07316088 | Oui Therapeutics, Inc. | Phase 2 |
| Not Yet Recruiting | Psilocybin-Assisted Therapy for Sexual Assault-Related PTSD NCT06902974 | Sunstone Medical | Phase 2 |
| Recruiting | Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study NCT07227337 | Johns Hopkins University | N/A |
| Not Yet Recruiting | Department of Defense PTSD Adaptive Platform Trial - Intervention D - SLS-002 NCT06816433 | Global Coalition for Adaptive Research | Phase 2 |
| Not Yet Recruiting | Department of Defense PTSD Adaptive Platform Trial - Intervention B - Vilazodone NCT05948579 | Global Coalition for Adaptive Research | Phase 2 |
| Not Yet Recruiting | Warrior CARE: Cannabis Behavioral Health NCT06381180 | Wayne State University | Phase 1 / Phase 2 |
| Recruiting | Multifaceted Intervention to Restore Resilience and Overcome Risk NCT06988787 | Icahn School of Medicine at Mount Sinai | N/A |
| Recruiting | Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Sym NCT07071350 | Virginia Commonwealth University | Phase 2 / Phase 3 |
| Completed | Progressive Muscle Relaxation Training in Post-traumatic Stress Disorder in Disasters NCT07164261 | Bitlis Eren University | N/A |
| Recruiting | Advanced Wireless Augmented Reality-Enhanced Exposure Therapy for Posttraumatic Stress Disorder NCT06740487 | Wayne State University | N/A |
| Completed | Aerobic Exercise Intervention for PTSD Symptoms and Sleep Quality After Earthquake NCT07474259 | Malatya Turgut Ozal University | N/A |
| Recruiting | Facilitation of Extinction Retention and Reconsolidation Blockade by IV Allopregnanolone in PTSD. NCT07079761 | Massachusetts General Hospital | Phase 2 |
| Recruiting | Induction of Dreaming With EEG and Anesthesia for Post-traumatic Stress Disorder NCT06577636 | Stanford University | Phase 2 |
| Not Yet Recruiting | NightWare and Cardiovascular Health in Women With PTSD NCT07021014 | University of Colorado, Denver | N/A |
| Not Yet Recruiting | Feasibility of a Digital Therapeutic for Adults With Posttraumatic Stress Disorder (PTSD) NCT06868446 | Oui Therapeutics, Inc. | Phase 1 |
| Recruiting | Experience of Staying in Intensive Care and Impact on Quality of Life NCT07339891 | University Hospital, Strasbourg, France | — |
| Recruiting | A Hybrid 1 Effectiveness-Implementation Trial of Partner-Assisted Prolonged Exposure for PTSD NCT06990191 | United States Department of Defense | N/A |
| Enrolling By Invitation | A Brief Intervention for PTSD - BWRT NCT07460817 | University of Bergen | N/A |
| Recruiting | Improving Sleep in Veterans With the Polytrauma Clinical Triad NCT06477796 | VA Office of Research and Development | N/A |
| Recruiting | Improving Mental Health in Forcibly Displaced Populations NCT06635486 | Boston Medical Center | N/A |
| Recruiting | Randomized Trial of Tele Vs. Clinic TF-CBT in Puerto Rico NCT06332209 | Medical University of South Carolina | N/A |
| Recruiting | Reducing Dropout and Improving Outcomes From PTSD Therapy: When to Switch Therapies or Stay the Course NCT06957067 | United States Department of Defense | N/A |
| Recruiting | MDMA-Assisted Therapy for Veterans With Moderate to Severe Post Traumatic Stress Disorder NCT05790239 | Stephen Robert Marder | Phase 2 |
| Enrolling By Invitation | Evaluation of a Trauma-Informed Partner Violence Intervention Program NCT06803043 | Boston University | N/A |
| Enrolling By Invitation | Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models NCT06792175 | Psyrin Inc. | — |
| Not Yet Recruiting | Behavioral Health Technician Delivered Written Exposure Therapy NCT06789887 | Palo Alto Veterans Institute for Research | N/A |
| Recruiting | Short-Term Recall and Reprocess Therapy for Post Traumatic Stress Disorder (PTSD) NCT06826937 | Ben-Gurion University of the Negev | N/A |
| Withdrawn | Pranayama for Posttraumatic Stress Disorder NCT05645588 | Universität Duisburg-Essen | N/A |
| Withdrawn | Safety and Tolerability of Psilocybin in Post-Traumatic Stress Disorder NCT05562973 | Johns Hopkins University | Phase 1 |
| Completed | Pivotal Trial of SAT-014 for Trauma and Stressor-Related Disorder Symptoms NCT06734858 | S-Alpha Therapeutics, Inc. | N/A |
| Not Yet Recruiting | Exploring Clinical Study Experiences of People With Post Traumatic Stress Disorder NCT06146049 | Power Life Sciences Inc. | — |
| Recruiting | MDMA-Assisted CBCT for PTSD vs CBCT RCT NCT06044675 | Remedy | Phase 2 |
| Active Not Recruiting | Web-administered STAIR for Patients on Behavioral Health Waitlists NCT06431022 | Boston Medical Center | N/A |
| Recruiting | Rapid Treatment of PTSD With Accelerated Non-Invasive Brain Stimulation NCT06544408 | Florida State University | N/A |
| Recruiting | MDMA-assisted Massed Prolonged Exposure for PTSD NCT06117306 | Healing Breakthrough | Phase 3 |
| Recruiting | A Pilot Study of Trauma-Focused Cognitive-Behavioral Therapy for Treatment of Post-traumatic Stress in Adults. NCT06516874 | University of Talca | N/A |
| Recruiting | Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors NCT06538246 | Duke University | N/A |
| Active Not Recruiting | MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experienc NCT05106361 | Michigan State University | N/A |
| Recruiting | Cognitive Control Training for Extinction in PTSD NCT06629064 | VA Office of Research and Development | N/A |
| Withdrawn | Efficacy of Traumatic Memory Modification Using Memory Reconsolidation and Propranolol Among Adolescents With NCT04921982 | Rennes University Hospital | Phase 2 |
| Not Yet Recruiting | Internet-delivered Trauma-focused Cognitive-behavioral Therapy as an Early Intervention After Sexual Trauma NCT06502106 | Karolinska Institutet | N/A |
| Recruiting | Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33) NCT06273527 | University of California, San Diego | Phase 2 / Phase 3 |
| Completed | Written Exposure Therapy to Improve Recovery Among Sexual Assault Survivors NCT06571513 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | Early Support After Exposure to Trauma NCT06592677 | Norwegian Center for Violence and Traumatic Stress Studies | N/A |
| Recruiting | Evaluation of the Parenting in the Moment Online Program for Forcibly Displaced Families NCT06548126 | Arizona State University | N/A |
| Recruiting | Body-oriented Psychotherapy for Individuals With a History of Child Maltreatment and Trauma-related Symptoms NCT06549777 | Monique Pfaltz | N/A |
| Not Yet Recruiting | Condensed Digital Prolonged Exposure for Individuals Treated Within Somatic Trauma Care. NCT06318195 | Karolinska Institutet | N/A |
| Recruiting | Silexan in the Treatment Of Posttraumatic Stress Disorder Trial NCT06412757 | Deakin University | Phase 3 |
| Not Yet Recruiting | Characterization of Olfactory Perception in Post-Traumatic Stress Disorder NCT06494306 | Hospices Civils de Lyon | — |
| Completed | The Effects of a Psychoeducational Intervention on Health and Performance-based Outcomes of Veterans Diagnosed NCT06403514 | Nova Southeastern University | N/A |
| Completed | Trauma-Informed Goal Management Training for Individuals With Post-traumatic Stress Disorder (PTSD) NCT06354361 | McMaster University | N/A |
| Recruiting | Sleep and Emotion Processing in Adolescent Post-traumatic Stress Disorder NCT06341413 | University of Wisconsin, Madison | N/A |
| Recruiting | Clinician-Assisted Videofeedback Exposure-Approach Therapy (CAVEAT) Trial NCT05927324 | University of Lausanne Hospitals | N/A |
| Not Yet Recruiting | Biopsychosocial Effectiveness of Exercise Trainings in Earthquake Survivors With Post-Traumatic Stress Disorde NCT06390618 | Erkin Oğuz SARI | N/A |
| Recruiting | eTMS for Veterans and First Responders With PTSD NCT06294106 | Virginia Polytechnic Institute and State University | N/A |
| Active Not Recruiting | A Study of Psilocybin for PTSD NCT06407635 | Johns Hopkins University | Phase 1 |
| Recruiting | Imaging Traumatic Stress and Alcohol Use Disorder With [18F]Bavarostat NCT06371404 | Yale University | — |
| Recruiting | Stroke Rehabilitation Utilizing Therapeutical Methods Designed for Nature Environments NCT06633146 | Joint Authority for Päijät-Häme Social and Health Care | N/A |
| Recruiting | Psychotherapy Effects on Reward Processing in PTSD NCT06096740 | University of Texas at Austin | N/A |
| Recruiting | Brief Transdiagnostic Treatment for Anxiety Disorders and Post-traumatic Stress Disorder (PTSD) in South Afric NCT06289621 | Massachusetts General Hospital | N/A |
| Withdrawn | The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD. NCT03752918 | Yale University | Phase 1 |
| Recruiting | Open Trial of Trauma-focused Psychodynamic Psychotherapy for People Living With HIV and PTSD NCT05929911 | Montefiore Medical Center | N/A |
| Recruiting | Enhancing Purpose and Well-Being Through a Volunteering Experience Connecting Veterans With English Language L NCT06324383 | University of Michigan | N/A |
| Completed | An Evaluation of the Safety and Efficacy of Methylone for the Treatment of PTSD NCT06215261 | Transcend Therapeutics | Phase 2 |
| Unknown | Feasibility Study of the Self-Care Immediate Stabilization Procedure (ISP) ® After a Traumatic Experience NCT06277973 | Tel Aviv University | N/A |
| Recruiting | The Effects of Very Brief Exposure on PTSD in U.S. Combat Veterans NCT06218381 | Children's Hospital Los Angeles | N/A |
| Completed | A Single, Ascending Dose Evaluation of the Safety, Pharmacokinetics of Methylone in Healthy Subjects NCT06303648 | Transcend Therapeutics | Phase 1 |
| Recruiting | Repetitive Transcranial Magnetic Stimulation Plus Reactivation Therapy Efficacy on PTSD Symptom Severity in Re NCT06111976 | Assistance Publique - Hôpitaux de Paris | N/A |
| Recruiting | Personalized Brain Stimulation to Treat Chronic Concussive Symptoms NCT06073886 | University of California, Los Angeles | Phase 2 |
| Completed | An Evaluation of the Long-term Efficacy and Safety of Methylone for the Treatment of PTSD NCT06237426 | Transcend Therapeutics | Phase 2 |
| Active Not Recruiting | An Adjunctive Neurofeedback Training Program to Enhance Wellness Among Trauma-Exposed Postpartum Mothers NCT06054412 | Wayne State University | N/A |
| Completed | The Feasibility of Cognitive Process Therapy in Earthquake-affected Population With Mental Health Problems in NCT06136481 | Koç University | N/A |
| Recruiting | Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress NCT05701111 | Stanford University | N/A |
| Unknown | AI to Support Mental Health Case Management Providers NCT06280170 | Eleos Health | N/A |
| Active Not Recruiting | TMS for PTSD and Blood Pressure NCT05512143 | Lifespan | N/A |
| Recruiting | MDMA for AUD/PTSD Comorbidity NCT05943665 | Carolina L Haass-Koffler | Phase 2 |
| Completed | Rare Group Problem Management Plus NCT06548022 | Children's National Research Institute | N/A |
| Recruiting | Effect of Attentional Therapy on Post-traumatic Stress Disorder NCT05331534 | University Hospital, Lille | N/A |
| Completed | Pilot Testing of an Equity Focused and Trauma-informed Communication Intervention During Family-centered Round NCT05618652 | Duke University | N/A |
| Recruiting | TMS-fNIRS Personalized Dosing NCT05916417 | Florida State University | N/A |
| Not Yet Recruiting | Study of the Correlation Between Post-traumatic Stress Disorder and Paradoxical Sleep Behavior Disorder NCT06221865 | University Hospital, Clermont-Ferrand | — |
| Enrolling By Invitation | Financial Incentives for Veteran Therapy Completion NCT06234371 | Christopher Cronin | N/A |
| Recruiting | Pimavanserin for Insomnia in Veterans With PTSD NCT05441280 | VA Office of Research and Development | Phase 2 |
| Unknown | Evaluation of Psilocybin-Assisted Psychotherapy in Treating Severe Depression in Patients With PTSD NCT06141876 | Apex Labs Ltd. | Phase 2 |
| Recruiting | Qualitative Study on the Perception of Changes in the Psychotherapy of Traumatized Young People NCT06138522 | Assistance Publique - Hôpitaux de Paris | — |
| Not Yet Recruiting | TREATMENT OF POST-TRAUMATIC STRESS DISORDER USING AUGMENTED IMAGINATION EXPOSURE PSYCHOTHERAPY WITH VOCAL FEED NCT06129981 | University Hospital, Lille | N/A |
| Active Not Recruiting | CRISOL Mente: A Multilevel Community Intervention to Reduce Mental Health Disparities Among Latinos NCT06139159 | Drexel University | N/A |
| Recruiting | Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant NCT05948540 | Global Coalition for Adaptive Research | Phase 2 |
| Recruiting | Department of Defense PTSD Adaptive Platform Trial - Intervention A - Fluoxetine NCT05948553 | Global Coalition for Adaptive Research | Phase 2 |
| Recruiting | Department of Defense PTSD Adaptive Platform Trial - Master Protocol NCT05422612 | Global Coalition for Adaptive Research | Phase 2 |
| Unknown | Feasibility of an Intervention for Somatic Flashbacks in PTSD NCT05996913 | University College, London | N/A |
| Completed | tDCS and Inhibitory Control in PTSD NCT06100731 | Gopalkumar Rakesh | N/A |
| Recruiting | Approach-Avoidance and Alcohol Challenge Study in PTSD NCT06002633 | University of Texas at Austin | N/A |
| Completed | Testing the Effectiveness of a Therapist-Assisted Self-Management Program for Veterans Who Finished PTSD Thera NCT05797441 | VA Office of Research and Development | N/A |
| Terminated | Alexithymia Intervention for Suicide NCT05724953 | VA Office of Research and Development | Phase 1 |
| Unknown | Open-Label Dose-Ranging Study of Oral SM-001 in Healthy Adults NCT05894902 | Advanced Integrative Medical Science Institute | Phase 1 |
| Withdrawn | Network-based Neurofeedback in PTSD NCT04875221 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Recruiting | RIVER At Home Ketamine Protocols NCT06070766 | RIVER Foundation | — |
| Terminated | Project BrEAtHe: A Culturally Tailored MBSR Intervention for Young Adult Black Men NCT07009977 | UConn Health | N/A |
| Unknown | The Effect of Aquatic Physiotherapy on Veterans Suffering From PTSD - a 40-week Pilotproject NCT05992649 | vandfys | N/A |
| Recruiting | MDMA-assisted Prolonged Exposure Therapy for Comorbid Alcohol Use Disorder and Post-traumatic Stress Disorder NCT05709353 | University of Sydney | Phase 2 |
| Recruiting | People Bereaved by Violent Death : Negative Event Biases and Temporal Perception NCT05874362 | Hôpital le Vinatier | N/A |
| Recruiting | Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine NCT05915013 | Yale University | Phase 1 |
| Recruiting | Efficacy of Internet-delivered Cognitive-behavior Therapy for PTSD NCT05934162 | Karolinska Institutet | N/A |
| Recruiting | Intensive Treatment Versus Standard Weekly Prolonged Exposure for Adults With Post-Traumatic Stress Disorder NCT05934175 | Karolinska Institutet | N/A |
| Completed | Effect of Baclofen to Prevent Post-Traumatic Stress Disorder NCT05877807 | Nantes University Hospital | — |
| Unknown | NeuroGlove PTSD Study NCT06050590 | NeuroGlove LLC | N/A |
| Recruiting | Targeting the Default Mode Network: A TMS-fMRI Study NCT05646732 | Allyson Rosen | N/A |
| Completed | Empathy in Post-traumatic Stress Disorder in Comparaison to a Control Population NCT05617781 | Centre Hospitalier Universitaire de Nice | — |
| Active Not Recruiting | Efficacy of Virtual Warrior Renew Therapy for Veterans Who Experienced Military Sexual Trauma NCT05776719 | Seattle Institute for Biomedical and Clinical Research | N/A |
| Unknown | Reversal of Battle-Related Aging (ROBRA) in a Special Operations Forces Cohort NCT05855876 | Stella Center | — |
| Recruiting | Effectiveness of Digital Cognitive Behavioral Therapy for Insomnia in Frontline Health Care Workers (The HCW-C NCT05816304 | University Health Network, Toronto | N/A |
| Withdrawn | Adaptation of the PCIP for Spanish Speaking Adolescents and Families NCT05899322 | University of California, Los Angeles | N/A |
| Completed | Designing a Mobile App to Support Academic Success for Student Veterans NCT05344092 | VA Office of Research and Development | N/A |
| Recruiting | An Open Label Pilot Study of IV Brexanolone for the Treatment of Post-Traumatic Stress Disorder NCT05254405 | Donald Jeffrey Newport | Phase 4 |
| Unknown | Preliminary Effectiveness of Individual and Group MDMA-assisted Therapy for Israeli Veterans With PTSD and Mor NCT05732155 | HaEmek Medical Center, Israel | Phase 2 |
| Recruiting | Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers NCT05751473 | University of Michigan | N/A |
| Recruiting | Effectiveness of Trauma Therapy Using Prolonged Exposure for Patients With PTSD and a Comorbid Psychotic Disor NCT06048172 | Medicalschool Hamburg | N/A |
| Completed | Reconsolidation Blockade of Intrusive Trauma- and Cocaine-related Memories NCT05902819 | Psychiatric University Hospital, Zurich | N/A |
| Completed | Evaluating Implementation and Impact of PeerOnCall, a Mobile Health Approach to Peer Support for Canadian Publ NCT05429619 | McMaster University | — |
| Recruiting | Multi-session fMRI-Neurofeedback in PTSD NCT05456958 | Andrew Nicholson | N/A |
| Recruiting | Effects of a Digital Diary on the Psychological Well-being of Former ICU Patients. NCT06237699 | Erasmus Medical Center | — |
| Recruiting | Brain Health & Wellness Classes for Veterans With Traumatic Brain Injury NCT06150196 | East Bay Institute for Research and Education | N/A |
| Withdrawn | Adaptation of the PCIP for Children Aged 6 to 11 NCT05606172 | University of California, Los Angeles | N/A |
| Completed | Studying the Modification of Attention Bias Remotely After Trauma NCT04888169 | University of California, San Francisco | N/A |
| Completed | Effectiveness of Sana Treatment in Post-Traumatic Stress Disorder (PTSD) NCT05319405 | Sana Health | N/A |
| Completed | Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individ NCT05520190 | University of Rochester | N/A |
| Recruiting | The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects NCT05786066 | Yale University | Phase 2 |
| Recruiting | Mechanisms Underlying Efficacy of Prolonged Exposure NCT05788302 | Massachusetts General Hospital | N/A |
| Unknown | Prevalence of Post-traumatic Stress Disorder and Trauma Symptoms in a General Population Sample NCT05679245 | Parc de Salut Mar | — |
| Completed | Exploring the Correlation Between Post Traumatic Stress Disorder, Perceived Stress and Scar Pruritus in Burn P NCT05885321 | National Taiwan University Hospital | — |
| Completed | A Study to Assess the Use of Methylone in the Treatment of PTSD NCT05741710 | Transcend Therapeutics | Phase 1 / Phase 2 |
| Recruiting | PTSD of Surgeons or Anesthesiologists on Prognosis of Surgical Patients NCT05732116 | Xijing Hospital | — |
| Unknown | Eye Movement Desensitisation and Reprocessing (EMDR) to Improve Mental Health Following Intensive Care Admissi NCT05591625 | University Hospital Southampton NHS Foundation Trust | N/A |
| Active Not Recruiting | An Intervention to Enhance Well-Being in Trauma Exposed New Mothers NCT05474534 | Wayne State University | N/A |
| Completed | Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for PTSD NCT05242367 | Neurovalens Ltd. | N/A |
| Completed | Clinical Study About the Effects of Scuba Diving on Post Traumatic Stress Disorder (PTSD) NCT04343924 | Centre Hospitalier Universitaire de Nice | N/A |
| Completed | Identification of the Clinical Specificities of Complex Posttraumatic Stress Disorder NCT05592652 | University Hospital, Tours | N/A |
| Completed | Transcranial Direct Current Stimulation (tDCS) in Human Subjects With PTSD Receiving an Exposure-based, Behavi NCT05419999 | The University of Texas Health Science Center at San Antonio | N/A |
| Recruiting | OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit NCT05156112 | VA Office of Research and Development | N/A |
| Unknown | Neurofeedback for Post-Traumatic Stress Disorder NCT05123690 | Steinn Steingrimsson | N/A |
| Withdrawn | Goal Management Training in Individuals With PTSD NCT04457271 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Recruiting | Innovative Multimodal and Attention Training to Improve Emotion Communication in Veterans With TBI and PTSD NCT05478759 | VA Office of Research and Development | N/A |
| Recruiting | Disrupting Fear-based Memory Consolidation NCT05560113 | Emory University | N/A |
| Completed | GBV, Primary Trauma & Trauma Resilience & Understanding Self-help Therapy Utilization in Uganda NCT06073964 | Kampala International University | N/A |
| Active Not Recruiting | Stellate Ganglion Block for PTSD NCT05169190 | VA Office of Research and Development | N/A |
| Completed | Written Exposure Therapy for PTSD in a Virtual, Group-based Format NCT05553249 | University of Manitoba | — |
| Recruiting | NYSCF Scientific Discovery Biobank NCT06203106 | New York Stem Cell Foundation Research Institute | — |
| Recruiting | CO2 Reactivity as a Biomarker of Non-Response to Exposure-Based Therapy NCT05467683 | University of Texas at Austin | N/A |
| Unknown | Beyond Silence: Advancing E-mental Health Solutions to Support Canadian Healthcare Workers NCT05514093 | McMaster University | — |
| Recruiting | Predictability of the Clinical Global Impression Scale (CGI) in Post Immediate in Psychotraumatic Impact NCT05358067 | Centre Hospitalier Arras | — |
| Completed | A Feasibility Study of Internet Delivered Prolonged Exposure NCT05560854 | Karolinska Institutet | N/A |
| Completed | Effect of Eye Movement Desensitization and Reprocessing Therapy 2.0 Online Group Protocol NCT05596903 | Academy of Therapeutic Sciences, Turkey | N/A |
| Unknown | Effectiveness of a Brief Intensive Trauma Treatment for Adolescents With (s)PTSD: a Multi-center RCT NCT06143982 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | N/A |
| Unknown | Investigating the Therapeutic Effects of Psilocybin in Treatment-Resistant Post-Traumatic Stress Disorder NCT05243329 | Halucenex Life Sciences Inc. | Phase 2 |
| Recruiting | Determining the Right Acupuncture for Good Recovery Over Neuropsychiatric Trauma NCT05516862 | Paul Crawford | N/A |
| Terminated | Efficacy of a Multi-level School Intervention for LGBTQ Youth NCT05541406 | Washington University School of Medicine | N/A |
| Recruiting | Exploring Virtual Reality Adventure Training Exergaming NCT05563805 | The University of Texas at Arlington | N/A |
| Enrolling By Invitation | Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD) NCT05565352 | Medical University of Gdansk | — |
| Completed | Competitive Revision for CLARO: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses NCT04634279 | RAND | N/A |
| Completed | Diet Induced Ketosis for Patients With Posttraumatic Stress Disorder (PTSD), a Feasibility Study NCT05415982 | Jens Rikardt Andersen | N/A |
| Completed | Written Exposure Therapy to Improve Lives After Stress Exposure NCT05390775 | University of North Carolina, Chapel Hill | N/A |
| Recruiting | Efficacy of Eye Movement Desensitization & Reprocessing vs Cognitive Behavioral Therapy in Post-Traumatic Stre NCT06435052 | Khushal Khan Khattak Univeristy, Karak, Pakistan | N/A |
| Completed | Perceptions of MDMA-Assisted Therapy Among Veterans With PTSD NCT05895318 | Albany Research Institute, Inc. | — |
| Completed | Using Mobile Technology to Address the Trauma Mental Health Treatment Gap NCT05374408 | University of Nebraska | — |
| Active Not Recruiting | Effects of Stellate Ganglion Block in Post-traumatic Stress Disorder NCT05391971 | NYU Langone Health | Phase 4 |
| Active Not Recruiting | RESILIENT : A Self-Managed Online Platform for Victims of Sexual Assault NCT05811897 | Laval University | N/A |
| Unknown | "OnCall": Implementation Study of M-Health for Canadian Public Safety Personnel NCT05255419 | McMaster University | — |
| Withdrawn | Warrior CARE: Naturalistic Observation and Harm Reduction NCT05386862 | Wayne State University | N/A |
| Recruiting | Early Psychological Intervention After Rape NCT05489133 | St. Olavs Hospital | N/A |
| Unknown | Efficacy of a Brief Intervention to Improve Sexual and Gender Minorities' Mental Health: Randomized Controlled NCT05349877 | Pontificia Universidade Católica do Rio Grande do Sul | N/A |
| Completed | The Safety and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder NCT05312151 | COMPASS Pathways | Phase 2 |
| Completed | Efficacy of Evidence-Based PTSD Treatment Via Prebiotic Supplementation NCT05424146 | Rush University Medical Center | N/A |
| Completed | Adaptation and Evaluation of the KEEP Model NCT05816421 | Oregon Social Learning Center | N/A |
| Unknown | Effectiveness of a Blended Care Parenting Intervention for Parents With PTSD (KopOpOuders-PTSD) NCT05237999 | Arkin | N/A |
| Unknown | Childbirth-related Post-traumatic Stress Disorder in Switzerland: The Swiss Cohort on Traumatic Childbirth and NCT05865704 | Centre Hospitalier Universitaire Vaudois | — |
| Completed | Program for Alleviating and Resolving Trauma and Stress 2 NCT05095428 | Cambridge Health Alliance | N/A |
| Unknown | Studying the Effectiveness and Implementation of Sudarshan Kriya Yoga for Canadian Veterans With PTSD NCT05235828 | Mount Sinai Hospital, Canada | N/A |
| Completed | Women's Responses to a Mindfulness-Based Body Scan: A Pilot Study NCT05137769 | Vanderbilt University | N/A |
| Completed | Intensiv Inpatient Trauma Treatment. A Pilotstudy. NCT05342480 | Oslo University Hospital | N/A |
| Completed | "Connected Caesarean Section": Creating a Virtual Link Between Mothers and Their Infants to Improve Maternal C NCT05319665 | Centre Hospitalier Universitaire Vaudois | N/A |
| Enrolling By Invitation | Effect of Ketamine and Etomidate During RSI on Long Term Outcomes NCT06179485 | Vanderbilt University Medical Center | — |
| Unknown | Neuropsychological Sequelae and Long COVID-19 Fatigue NCT05323318 | Centro Hospitalar Universitario do Algarve | — |
| Unknown | Ketamine and Epigenetic Aging NCT05294835 | TruDiagnostic | Phase 2 |
| Completed | Study of the Association Between the Type of Attachment and the Risk of Post-Traumatic Stress Disorder NCT05020197 | Hospices Civils de Lyon | — |
| Completed | Exploring the Psycho-traumatic Impact of a Violent Act Commited at the Bordeaux-Gradignan Penitentiary Center NCT05026450 | Centre Hospitalier Charles Perrens, Bordeaux | — |
| Completed | Therapeutic Effects of the Processing of Positive Memories Technique on Posttrauma Health NCT06680193 | University of North Texas, Denton, TX | N/A |
| Recruiting | Facilitation of Extinction Retention and Reconsolidation Blockade in PTSD NCT04468360 | Boston University | Phase 2 |
| Completed | Frontline Clinician Psilocybin Study NCT05163496 | University of Washington | Phase 3 |
| Completed | Activation of the Endocannabinoid System and Cognition NCT05226351 | Charite University, Berlin, Germany | N/A |
| Unknown | Acceptance and Commitment Group Therapy for Unaccompanied Minors NCT05218031 | University of Cyprus | N/A |
| Completed | Study of Affective Forecasting Skills in Post-traumatic Stress Disorder NCT05268965 | University Hospital, Lille | — |
| Completed | Characterization and Modulation of Traumatic Memories in PTSD Patients Using TMS NCT06372639 | Tel Aviv University | N/A |
| Enrolling By Invitation | Brief Prolonged Exposure Therapy Versus Clinical Standard to Reduce Posttraumatic Stress Post Spinal Cord Inju NCT05233111 | Baylor Research Institute | N/A |
| Withdrawn | Neurofeedback Effectiveness Trial in PTSD NCT04654130 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Withdrawn | Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)_VA On NCT03874845 | Ohio State University | N/A |
| Terminated | A Clinical Trial of PRAX-114 in Participants With Post-Traumatic Stress Disorder NCT05260541 | Praxis Precision Medicines | Phase 2 |
| Completed | A Feasibility Study of Intensive Treatment With Prolonged Exposure NCT05207462 | Karolinska Institutet | N/A |
| Completed | Effects of a Short-term Exercise Intervention on Sleep in Women Exposed to Trauma: A Randomized Controlled Tri NCT05097352 | University of Georgia | N/A |
| Terminated | Reducing Suicide Risk in Older Veterans Using Problem Solving Therapy NCT04763330 | VA Office of Research and Development | N/A |
| Recruiting | General Psychological Distress, PTSD, and Co-Morbidities in Healthcare Workers Consequent to COVID-19 NCT04626050 | Weill Medical College of Cornell University | N/A |
| Completed | Brief Cognitive Behavioral Conjoint Therapy for PTSD With Adjunctive Intranasal Oxytocin NCT05207436 | San Diego Veterans Healthcare System | Phase 2 |
| Unknown | Psychological Support for Intensive Care Nurses During the COVID-19 Pandemic: The PROACTIVE Feasibility Trial NCT05087186 | University Hospital Southampton NHS Foundation Trust | N/A |
| Terminated | A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans NCT03489122 | VA Office of Research and Development | N/A |
| Completed | Risk of Mental Health Conditions in Children and Young Adults With Inflammatory Bowel Disease and Influence on NCT05206734 | Momentum Data | — |
| Recruiting | rTMS-augmented Written Exposure Therapy for PTSD NCT05149534 | VA Office of Research and Development | N/A |
| Completed | Stellate Ganglion Block to Augment Trauma-focused Therapy Among Veterans With PTSD NCT05107752 | Ohio State University | Phase 2 |
| Withdrawn | Adolescent PCIP Randomized Feasibility Trial NCT05088915 | University of California, Los Angeles | N/A |
| Completed | Relationship Between Repetitive Negative Thinking and CBT Outcomes NCT06370559 | South London and Maudsley NHS Foundation Trust | — |
| Unknown | Biological Markers for Post-Traumatic Stress Disorder NCT05213858 | Assaf-Harofeh Medical Center | — |
| Completed | A Study of JZP150 in Adults With Posttraumatic Stress Disorder NCT05178316 | Jazz Pharmaceuticals | Phase 2 |
| Completed | ALTO-100 in MDD and/or PTSD NCT05117632 | Alto Neuroscience | Phase 2 |
| Completed | Improving Mental Health Following Early PREgnancy Loss Using a Brief Cognitive Task NCT05039853 | Imperial College London | N/A |
| Completed | A Study to Test Whether Taking BI 1358894 for 8 Weeks Helps Adults With Post-traumatic Stress Disorder NCT05103657 | Boehringer Ingelheim | Phase 2 |
| Withdrawn | Feasibility Trial of Pregnenolone for Posttraumatic Stress Disorder and Alcohol Use Disorder NCT04464148 | University of Texas Southwestern Medical Center | Phase 1 |
| Recruiting | Amygdala Memory Enhancement NCT05065450 | Washington University School of Medicine | N/A |
| Unknown | Experiences and Perceived Needs Among Parents of Children Exposed to Potentially Traumatic Events: a Qualitati NCT05185349 | University Hospital, Montpellier | — |
| Completed | Vedic Counselling for Women Victims of Domestic Abuse NCT05261230 | Active Natural Limited | N/A |
| Completed | Persistent PostConcussion-Like Symptoms and Post Traumatic Stress Disorder in Patients Presenting at the Emerg NCT04916678 | University Hospital, Bordeaux | N/A |
| Completed | Mobile Self-Tracking of Mental Health NCT05023252 | VA Office of Research and Development | N/A |
| Completed | Evaluation of a Tai Chi Resilience Training Program on Objective and Subjective Measures of Post Traumatic Str NCT04288830 | Johns Hopkins University | N/A |
| Completed | Psycho-traumatic Consequences of the COVID-19 Health Crisis Among Professionals in Emergency Services NCT05033223 | Hospices Civils de Lyon | N/A |
| Completed | Effects of an EMDR Intervention on Traumatic and Obsessive Symptoms NCT06110702 | University of Pisa | N/A |
| Completed | A Phase 2 Open-Label Treatment Development Study of MDMA-Assisted Cognitive Processing Therapy (CPT) for Postt NCT05067244 | Remedy | Phase 2 |
| Withdrawn | Integration of PE & Coping Long-Term With Active Suicide Program for PTSD & Suicide Risk in Military Families NCT04284410 | The University of Texas Health Science Center, Houston | N/A |
| Completed | Positive Processes and Transition to Health NCT04678232 | Case Western Reserve University | N/A |
| Unknown | Hypertension and Diabetes Assessment in the Rohingya Refugee Population and in the Host Communities in Banglad NCT04307875 | University Hospital Freiburg | — |
| Completed | Translingual Neurostimulation for the Virtual Treatment of Post-Traumatic Stress Disorder: A Feasibility Pilot NCT05112003 | HealthTech Connex Inc. | N/A |
| Completed | Psychological Effect of Explicit Recall After Sedation (PEERS) NCT04747379 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Recruiting | Fear and Avoidance in PTSD Patients NCT04770584 | The University of Texas Health Science Center, Houston | N/A |
| Completed | International Survey of Childbirth-Related Trauma - Swedish Part NCT06207916 | Region Östergötland | — |
| Completed | Expressing Personal Recollections in English or Spanish to Alleviate Traumatic Emotions (Exprésate) NCT05090839 | University of Miami | N/A |
| Unknown | Quality of Life After COVID-19 Related Acute respIratory Distress Syndrome Among ICU Survivors Patients in Ita NCT04860687 | Azienda Sanitaria-Universitaria Integrata di Udine | — |
| Unknown | Combined Ketamine and eCBT Intervention for PTSD NCT04771767 | Queen's University | Phase 2 |
| Unknown | Comparing Standard vs. Modified Reconsolidation Blockade for the Treatment of Psychological Trauma NCT04982211 | Douglas Mental Health University Institute | Phase 2 |
| Completed | MDMA-Assisted Psychotherapy in Veterans With Combat-Related, Refractory PTSD NCT04264026 | VA Loma Linda Health Care System | Phase 2 |
| Completed | A Phase 2b Study of BNC210 Tablet Formulation in Adults With Post-Traumatic Stress Disorder (PTSD) NCT04951076 | Bionomics Limited | Phase 2 |
| Recruiting | Interest of Cardiac Coherence in the Prevention of Chronic Post-traumatic Stress Disorder: Pilot Study NCT04701723 | Centre Hospitalier Universitaire de la Réunion | N/A |
| Recruiting | Effect of Pediatric Intensive Care Unit Diaries on PICS-p NCT06310109 | Bambino Gesù Children's Hospital IRCCS | N/A |
| Completed | The Effects of the Safe and Sound Protocol on PTSD Symptoms and Anxiety NCT04999852 | Indiana University | N/A |
| Recruiting | A Case Management Algorithm for Women Victims of Violence NCT04953273 | University Hospital, Lille | N/A |
| Completed | Increasing Treatment Efficacy Using SMART Methods for Personalizing Care NCT04642898 | Shannon E. Sauer-Zavala | N/A |
| Completed | Psychological Care of Oncology Patients With Post-traumatic Stress in the Context of a COVID-19 NCT04747249 | Centre Francois Baclesse | N/A |
| Completed | Exercise Training to Improve PTSD Symptoms and Health in Older Veterans NCT04199182 | VA Office of Research and Development | N/A |
| Unknown | Xenon Inhalation for Treatment of Posttraumatic Stress Disorder NCT03635827 | Nobilis Therapeutics Inc. | Phase 2 / Phase 3 |
| Completed | Neurotropism and Neuroinflammation in COVID-19 Patients With Delirium. NCT04785157 | University Hospital, Toulouse | — |
| Completed | Post-traumatic Stress, Signs of Depression and Burnout Syndrome Among Nursing Home Staff in Occitanie During t NCT04916275 | Centre Hospitalier Universitaire de Nīmes | — |
| Recruiting | Cannabidiol as a Treatment for PTSD and PTSD Comorbid With TBI NCT04550377 | NYU Langone Health | Phase 2 |
| Completed | Psychological Sequelae After Sudden Cardiac Death in the Patient and His Relatives NCT04921514 | University Hospital, Bordeaux | N/A |
| Recruiting | Goal-Directed Sedation in Mechanically Ventilated Infants and Children NCT04801589 | Vanderbilt University Medical Center | Phase 3 |
| Unknown | Cohort Follow-up of Survivors of Hospitalization for COVID-19 During the 2nd Wave of the Epidemic in France NCT04934202 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Mindful Attention Training Workshop for Firefighters NCT04909216 | University of Houston | N/A |
| Recruiting | Presence of PTSD and Emotion Dysregulation Among Inpatients With Substance Use Disorder NCT06345053 | Norwegian University of Science and Technology | N/A |
| Completed | Virtual Mantram Program for Patients With PTSD and SUD NCT05058963 | Centre for Addiction and Mental Health | N/A |
| Unknown | Implementation of a Post-traumatic Stress Disorder PREvention Program Within the French ARmy NCT05094531 | Direction Centrale du Service de Santé des Armées | N/A |
| Completed | Prolonged Exposure Therapy for PTSD and Opioid Use Disorder NCT04104022 | University of Vermont | N/A |
| Recruiting | Neuromodulation and Neurorehabilitation for mTBI NCT03819608 | Northwestern University | N/A |
| Completed | Yoga and Mantram for Chronic Pain and PTSD NCT03816007 | VA Office of Research and Development | N/A |
| Unknown | STRESS From in Charge Relative Facing the Announcement of Decisions Limiting or Stopping Treatments in Emergen NCT04785807 | Hospices Civils de Lyon | N/A |
| Active Not Recruiting | The Norwegian Addiction, Pain and Trauma Study NCT04908410 | University Hospital, Akershus | — |
| Recruiting | Responsive Neurostimulation for Post-Traumatic Stress Disorder NCT04152993 | VA Greater Los Angeles Healthcare System | EARLY_Phase 1 |
| Completed | Effects of Antagonistic Actions in Response to Trauma Exposure NCT04617769 | University of Texas at Austin | N/A |
| Completed | Short-term Intervention and Health Trajectories After Mass Trauma NCT05042323 | Norwegian Center for Violence and Traumatic Stress Studies | N/A |
| Unknown | Hot Water Immersion Therapy for Mental Health NCT04793542 | Lakehead University | N/A |
| Recruiting | Lofexidine Combined With Buprenorphine for Reducing Symptoms of PTSD and OU Relapse in Veterans NCT04360681 | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | Phase 2 |
| Terminated | Antidepressant Response in Older Adults With Comorbid PTSD and MDD NCT04697693 | New York State Psychiatric Institute | Phase 4 |
| Completed | AWARENESS Trial (AWARENESS) of Storytelling Through Music in Healthcare Workers NCT04775524 | Dana-Farber Cancer Institute | N/A |
| Completed | Acceptance and Commitment Therapy to Improve Social Support for Veterans With PTSD NCT04567680 | VA Office of Research and Development | N/A |
| Withdrawn | Observational Study of the Evaluation of Post Traumatic Stress Post Stroke NCT04299841 | Ch Mont de Marsan | — |
| Unknown | Improving Therapeutic Learning for PTSD NCT04558112 | University of Wisconsin, Madison | Phase 2 |
| Completed | Effect of TMS on PTSD Biomarkers NCT04563078 | Emory University | N/A |
| Withdrawn | Study of the Safety and Efficacy of Nabiximols Oromucosal Spray Versus Placebo in Patients With Post-traumatic NCT04592159 | Jazz Pharmaceuticals | Phase 2 / Phase 3 |
| Unknown | Evaluation of the Psychosocial Impact on Health Professionals Exposed During COVID 19 Coronavirus Pandemic NCT04752839 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | — |
| Unknown | Effectiveness of Trauma Therapy in Patients With PTSD and Comorbid Psychotic Disorder NCT04911010 | University of Hamburg-Eppendorf | N/A |
| Completed | Tools for Health and Resilience Implemented After Violence Exposure (Project THRIVE) NCT03703258 | University of Washington | N/A |
| Completed | Collaboration Leading to Addiction Treatment and Recovery From Other Stresses NCT04559893 | RAND | N/A |
| Unknown | Development of Mental Health Outcomes Following the 2020 Petrinja Earthquake NCT04911933 | Neuropsychiatric Hospital dr Ivan Barbot | N/A |
| Withdrawn | Videomusic and Psychic Trauma NCT04664907 | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | N/A |
| Completed | Effect of Exercise on Post-traumatic Growth Among Health Care Providers With Post-traumatic Stress NCT04592770 | University of Karachi | N/A |
| Completed | Program for Alleviating and Resolving Trauma and Stress 1 NCT04713501 | Cambridge Health Alliance | N/A |
| Active Not Recruiting | Targeted Plasticity Therapy for Posttraumatic Stress Disorder NCT04064762 | Baylor Research Institute | N/A |
| Unknown | Lifestyle Intervention to Reduce Body Weight and Systemic Inflammation Among World Trade Center Responders NCT05138198 | Stony Brook University | N/A |