NCT07485231

Nitric Oxide (NO) and Endothelial Dysfunction in Women With PTSD

Role of Nitric Oxide (NO) in Endothelial Dysfunction in Premenopausal Women With Posttraumatic Stress Disorder (PTSD)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: University of Minnesota · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

This research study is conducted to better understand why women with post-traumatic stress disorder (PTSD) have higher risk of cardiovascular disease as they get older. This study looks at how trauma and PTSD affect blood vessels in young women by testing whether the dietary supplement beetroot juice might help improve the function of blood vessels in women suffering from PTSD.

Conditions

• Post Traumatic Stress Disorder
• Trauma

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Beetroot Juice	We will use James White Beet It sports shot (70ml), which contains 400 mg of dietary nitrate
DIETARY_SUPPLEMENT	Placebo Juice	James White Nitrate Depleted Placebo ( 70 ml) will be used as a placebo

Timeline

• Start date: 2026-02-18
• Primary completion: 2028-05-01
• Completion: 2028-05-01
• First posted: 2026-03-20
• Last updated: 2026-04-03

Locations

1 site across 1 country: United States