| Suspended | FRAME, External Support for Lower Limb Autologous Grafts NCT04003480 | Vascular Graft Solutions Ltd. | N/A |
| Not Yet Recruiting | Artificial Intelligence for Early Detection of Peripheral Artery Disease NCT06505317 | University of California, San Diego | N/A |
| Not Yet Recruiting | CT Body Composition as Predictor of Exercise Therapy Outcome in Peripheral Arterial Disease NCT07433309 | Nemocnice AGEL Trinec-Podlesi a.s. | — |
| Recruiting | EVERO Drug-coated Balloon (DCB) Randomized Trial NCT07144150 | Cook Research Incorporated | N/A |
| Not Yet Recruiting | Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone in Europ NCT07472439 | Angiodynamics, Inc. | N/A |
| Not Yet Recruiting | Case-Specific Health Care Professional Clinical Survey of Liberant™ Thrombectomy System NCT07335341 | Medtronic Endovascular | — |
| Not Yet Recruiting | Evaluation of the Safety and Efficacy of the Long (> 150mm) Passeo-18 Lux Drug-coated Balloon of Teleflex in t NCT07385573 | KANDO Research | N/A |
| Not Yet Recruiting | Near Infrared Spectroscopy Imaging of Change in Tissue Oxygenation to Assess Peripheral Artery Disease NCT07397494 | Kent Imaging Inc | — |
| Not Yet Recruiting | Study to Image Inflammatory Activity of a Fluorescence Imaging Agent in Excised Human Artery Plaques NCT06957821 | Massachusetts General Hospital | EARLY_Phase 1 |
| Recruiting | Tele-assessment and Face-to-face Assessment of the 30-second Sit-stand Test in Peripheral Artery Disease NCT07497360 | Izmir Democracy University | — |
| Recruiting | Randomized Clinical Trial for Ewing Amputation in the VA NCT05437562 | VA Office of Research and Development | N/A |
| Recruiting | Road Mapping Guided Puncture Versus Ultrasound Guided Puncture During Retrograde Angioplasty Feasibility and S NCT07427108 | Sohag University | N/A |
| Not Yet Recruiting | A Study of SRSD107 in Participants With Chronic Coronary and/or Peripheral Arterial Disease NCT07318155 | Sirius Therapeutics Co., Ltd. | Phase 2 |
| Not Yet Recruiting | Evaluation of Safety, Tolerability and Preliminary Efficacy of Etrinabdione in Patients With Peripheral Arteri NCT06774040 | VivaCell Biotechnology España | Phase 2 |
| Recruiting | Intravascular Ultrasound Imaging Guidance for Optimal Revascularization of Limb Arteries NCT07353905 | Baylor Research Institute | N/A |
| Recruiting | Replexa+ Shortwave Diathermy Device for Patients Diagnosed With Peripheral Artery Disease and Peripheral Neuro NCT07336381 | Indiana University | N/A |
| Completed | Deep Breathing Exercise for Pain and Hemodynamic Stability in Patients After Peripheral Percutaneous Angioplas NCT07464990 | Kufa University | N/A |
| Not Yet Recruiting | REVASC-PAD: REstricted VASCular Exercise for Peripheral Arterial Disease - A Feasibility Study at University o NCT07223437 | University of Tennessee Graduate School of Medicine | N/A |
| Recruiting | Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease NCT07223593 | Eli Lilly and Company | Phase 3 |
| Not Yet Recruiting | Impact of Virtual Reality on Patient Pain During Lower Limb Revascularization Via Endovascular Surgery Under L NCT07181434 | Poitiers University Hospital | N/A |
| Recruiting | Vascular Trial Associated Registry Pilot NCT07076082 | Corewell Health West | Phase 4 |
| Not Yet Recruiting | Mechanistic Study of Anti-Platelet Therapy in Atherosclerosis NCT07169513 | Guy's and St Thomas' NHS Foundation Trust | N/A |
| Recruiting | Advanta VXT and Flixene PMCF Registry NCT07161583 | Atrium Medical Corporation | — |
| Withdrawn | Peripheral Microvascular Resistance as a Predictor for Limb Salvage NCT06014242 | Hackensack Meridian Health | N/A |
| Not Yet Recruiting | Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progress NCT07187700 | Amsterdam UMC | — |
| Recruiting | Symptomatic and Systemic Atherosclerotic Plaque Activity in Patients With Peripheral Arterial Disease Using No NCT07472049 | University of Edinburgh | — |
| Enrolling By Invitation | Safety and Efficacy of Chocolate Balloon Catheter in Peripheral Arterial Disease (CHOCO-PAD) NCT06933992 | First People's Hospital of Hangzhou | — |
| Recruiting | Fuzzy Wale Compression Stockinet to Promote Healing Following Transtibial Amputation for Peripheral Arterial D NCT06308562 | Mayo Clinic | N/A |
| Not Yet Recruiting | Post-Market Study of ZENFLEX Pro Stent for Femoropopliteal Artery Lesions NCT07049120 | Zhejiang Zylox Medical Device Co., Ltd. | N/A |
| Completed | Effects of Body Awareness Therapy on Functional Capacity, With Peripheral Artery Disease NCT07250776 | Karadeniz Technical University | N/A |
| Recruiting | Personalised Multicomponent Exercise Programme in Peripheral Arterial Disease NCT06410521 | University of Trás-os-Montes and Alto Douro | N/A |
| Recruiting | Post-market Registry Study on the Safety and Efficacy of ZENFLEX Pro™ Peripheral Drug-eluting Stent System for NCT07122167 | MDCECRO LLC | N/A |
| Recruiting | VITUS Post-Market Registry NCT06832631 | OrbusNeich | — |
| Recruiting | Effects of Carnosine In Patients With Peripheral Arterial Disease Patients NCT06480760 | Shahid Baba | Phase 1 / Phase 2 |
| Not Yet Recruiting | Heat Therapy and Peripheral Artery Disease NCT06827691 | Manchester Metropolitan University | N/A |
| Not Yet Recruiting | Cell Therapy for Lower Limb Ulcers in Patients With Critical Limb Ischemia NCT06326203 | UPECLIN HC FM Botucatu Unesp | Phase 1 / Phase 2 |
| Recruiting | Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention NCT06544135 | University Hospitals Cleveland Medical Center | — |
| Not Yet Recruiting | Post-Market Evaluation of Active Thrombectomy and Proximal Aspiration During Lower Extremity Tibial Interventi NCT06929832 | Protexa Endovascular, Inc. | — |
| Enrolling By Invitation | Local or Systemic Effects: Mechanisms Related to Arm Crank Exercise - Comparison Between Individuals With and NCT06828172 | University of Nove de Julho | N/A |
| Recruiting | Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease NCT06952543 | Mayo Clinic | N/A |
| Active Not Recruiting | Investigational Study of SWM-831 to Treat Moderate and Severely Calcified Femoropopliteal Arteries NCT06938854 | Shockwave Medical, Inc. | N/A |
| Not Yet Recruiting | Heat Therapy for Peripheral Arterial Disease (HEATPAD) NCT06186505 | Norfolk and Norwich University Hospitals NHS Foundation Trust | N/A |
| Not Yet Recruiting | The Effectiveness of Covered Stent Viabahn and Drug-coated Balloon for Complex Femoropopliteal Artery Lesions NCT06752954 | First Affiliated Hospital of Jinan University | — |
| Recruiting | Prospective, Multicenter, Single-Arm Observational Study to Confirm the Safety and Clinical Performance of the NCT06758921 | Biotronik AG | — |
| Recruiting | SCS for Patient With Painful Diabetic Neuropathy and Peripheral Arterial Disease NCT06480786 | University of Nebraska | N/A |
| Recruiting | Impact of Nrf2 Activation on Macrovascular, Microvascular & Leg Function & Walking Capacity in Peripheral Arte NCT06319339 | University of Nebraska | EARLY_Phase 1 |
| Not Yet Recruiting | Evaluation of Perfusion and Oxygenation in Muscle of Patients With PAD Undergoing LER NCT06645353 | Medical University of Graz | — |
| Not Yet Recruiting | Ankle Arterial Doppler Waveform Assessment For Surveillance Following Lower Limb Revascularisation NCT06619223 | Imperial College London | — |
| Recruiting | Fisetin to Reduce Senescence and Mobility Impairment in PAD NCT06399809 | Northwestern University | Phase 2 |
| Completed | Structured Educational Program vs Standard Care in Pre-surgical Critical Limb Ischemia Patients NCT07201168 | Tulip Medicine | N/A |
| Recruiting | Pressure (Fractional Flow Reserve) and Flow (Vascular Flow Reserve) Measurements During Peripheral Arterial In NCT07052435 | Dr. Konstantinos Katsanos | — |
| Recruiting | Leg Exercise Assistive Paddling (LEAP) Therapy for Peripheral Artery Disease NCT06389149 | University of Nebraska | N/A |
| Not Yet Recruiting | Foot Perfusion by Dynamic Contrast Enhanced MRI in Patients With Peripheral Artery Disease NCT06525415 | Fudan University | — |
| Active Not Recruiting | A Real-world Study to Evaluate the Effectiveness of Intravascular Lithotripsy in Moderate to Severe Calcificat NCT06636968 | Shanghai Zhongshan Hospital | — |
| Not Yet Recruiting | Effect of Single-versus Double-limb Cycling Exercise on Blood Flow in Patients With Peripheral Artery Disease NCT06518590 | Cairo University | Phase 1 / Phase 2 |
| Not Yet Recruiting | Investigating Efficacy and Safety of JETi® in Arterial Occlusions in FEM-POP and Prox BTK-Lesions (JETART) NCT06434779 | Vascular Science LP GmbH | N/A |
| Completed | Oxygen Saturation in the Leg Musculature Affected by Peripheral Arterial Disease During Exercise on an Arm Erg NCT06491810 | University of Nove de Julho | — |
| Recruiting | Clinical Performance of the VESTO® Vascular Stent for Treatment of Iliac Peripheral Obstructive Arterial Disea NCT06573437 | Braile Biomedica Ind. Com. e Repr. Ltda. | — |
| Recruiting | The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial) NCT06321575 | Avantec Vascular | N/A |
| Recruiting | A Trail of Sperstent® Used for Residual Lesions of Femoropopliteal Arteries NCT06539689 | FrontAce Scientific Co., Ltd | N/A |
| Recruiting | Cognitive Impairment and Cerebral Haemodynamics in Individuals With Symptomatic Peripheral Arterial Disease NCT06369402 | University of Leicester | — |
| Recruiting | Passive Stretching in Peripheral Arterial Disease Patients NCT06420752 | University of Wisconsin, La Crosse | Phase 2 |
| Active Not Recruiting | Evaluation of Platelet Aggregability in Patients With Previous Acute Myocardial Infarction or Concomitant Lowe NCT06454045 | University of Sao Paulo | — |
| Recruiting | Treatment of TASC C and D Aortoiliac Lesions NCT06253312 | Clinical Centre of Serbia | — |
| Not Yet Recruiting | Peripheral Arterial Disease Biomarkers NCT06373302 | Norfolk and Norwich University Hospitals NHS Foundation Trust | — |
| Recruiting | Integrated Approach in Frail Older People with Atrial Fibrillation NCT06775028 | Heart Care Foundation | N/A |
| Recruiting | Prehabilitation and Rehabilitation in PAD NCT06566976 | Palo Alto Veterans Institute for Research | N/A |
| Recruiting | Coated or Chewable Aspirin and a Hybrid Strategy to Mitigate Adverse Effects of Air Pollution in Stable Athero NCT06541691 | Rajaie Cardiovascular Medical and Research Center | N/A |
| Completed | Adherence to Secondary Prevention Guidelines for Cardiovascular Risk NCT06450561 | Consorci Sanitari de l'Alt Penedès i Garraf | — |
| Unknown | IUA Committee Research Project on the Management of TASC C and D Aortoiliac Lesions NCT06260475 | Universidade do Porto | — |
| Recruiting | VTE Incidence After Rivaroxaban + Aspirin or SAPT After Lower-limb Revascularization NCT06873321 | Science Valley Research Institute | Phase 4 |
| Recruiting | Selective Coronary Revascularization in Peripheral Artery Disease Patients (SCOREPAD Trial) NCT06250790 | Pauls Stradins Clinical University Hospital | — |
| Recruiting | Comparison of a Lithotripsy vs Standard Preparation Followed by Stenting With Supera Stent in Femoropopliteal NCT06112171 | University of Leipzig | N/A |
| Recruiting | Using SnapshotNIR With Provocative Leg Maneuver for PAD Assessment NCT06237621 | Kent Imaging Inc | — |
| Recruiting | Early Percutaneous Transluminal Angioplasty in Diabetic Foot Syndrome (PTA-DFS) NCT06124586 | Heinrich-Heine University, Duesseldorf | N/A |
| Unknown | Feasibility of a Multifaceted Program to Reduce Cardiovascular Complications of Air Pollution NCT06261606 | Parham Sadeghipour | N/A |
| Recruiting | Efficacy and Safety of Stempeucel® in Patients With Critical Limb Ischemia (CLI) Due to Peripheral Arterial Di NCT05854641 | Cell Biopeutics Resources Sdn Bhd | Phase 4 |
| Completed | Effect of Subarachnoid Block and Femoropopliteal Block to Limb Perfusion in PAD Patients NCT06702202 | Indonesia University | N/A |
| Withdrawn | Vessel Deformations and Restenosis After Stenting of the Popliteal Artery NCT04700371 | Kantonsspital Aarau | N/A |
| Completed | Availability of Venous Conduits in Patients With Varicose Veins for Arterial Bypass Surgery NCT06332833 | Pirogov Russian National Research Medical University | — |
| Not Yet Recruiting | The Efficacy of Heparin-boned Viabahn Endoprosthesis and Paclitaxel-coated Balloons for Complex Femoropoplitea NCT06124755 | RenJi Hospital | N/A |
| Recruiting | The ROAMM-EHR Study NCT06263322 | University of Florida | N/A |
| Active Not Recruiting | REducing Diabetic MacrovascUlar Complications DuE to Peripheral Arterial Disease- REDUCE-PAD NCT05912218 | National Heart Centre Singapore | Phase 2 |
| Completed | Shear Stress in the Arteries of the Lower Limbs During Exercise in Patients With Peripheral Arterial Disease NCT06068504 | University of Nove de Julho | N/A |
| Recruiting | Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progress NCT06206369 | Amsterdam UMC, location VUmc | — |
| Recruiting | The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis NCT05811364 | W.L.Gore & Associates | N/A |
| Recruiting | The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry) NCT06315023 | Endologix | — |
| Recruiting | Development and Validation of the Modified Version of VascuQol Scale in Patients With Lower Extremity Peripher NCT06223217 | RenJi Hospital | — |
| Completed | Treadmill with TENS on Functional Capacity &muscle Oxygenation in PAD Patients NCT06061211 | Cairo University | N/A |
| Recruiting | RESPONSE-2-PAD to Reduce Sedentary Time in Peripheral Arterial Disease Patients NCT05961943 | National Institute for Prevention and Cardiovascular Health, Ireland | N/A |
| Terminated | A Study of Loco-Regional Liposomal Bupivacaine Injection NCT05992896 | Mayo Clinic | Phase 4 |
| Recruiting | BRING-UP Prevention NCT06275113 | Heart Care Foundation | — |
| Unknown | Rapamycin Coated Balloon Dilation Catheter for Arteriovenous Fistula NCT06029569 | Shanghai Bomaian Medical Technology Co., Ltd | N/A |
| Recruiting | SMART Exercise for PAD NCT06032065 | Northwestern University | Phase 3 |
| Recruiting | Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status NCT06009276 | University of Virginia | — |
| Not Yet Recruiting | Predictive Value of the Global Limb Anatomic Staging System (GLASS) in Patients With Critical Limb-threatening NCT05999669 | RenJi Hospital | — |
| Completed | Kaitoh Atherectomy FIH NCT05873452 | Terumo Medical Corporation | N/A |
| Completed | Foot Reflexology and Pain and Ankle Brachial Index and Walking Impairement NCT06001203 | Baskent University | N/A |
| Unknown | DIAbetes Maximal ACCeleration NCT05646147 | Leiden University Medical Center | N/A |
| Not Yet Recruiting | Atherectomy Followed With a Drug Coated Balloon in the Treatment of Long Femoropopliteal Lesions NCT05868564 | RenJi Hospital | N/A |
| Completed | FORWARD PAD IDE Study With the Shockwave Javelin IVL Catheter NCT05858905 | Shockwave Medical, Inc. | N/A |
| Unknown | Constrained Balloon Combined With Drug-coated Balloon Angioplasty for Femoropopliteal Lesion NCT05894460 | Xuanwu Hospital, Beijing | — |
| Recruiting | Use of Shockwave M5+/L6 IVL Catheter (Intravascular Lithotripsy) in Hostile and Calcified Iliac Access NCT05880641 | EndoCore Lab s.r.l. | — |
| Recruiting | Investigation of the Perfusion of Gluteal Muscle in Patients With Intermittent Gluteal Claudication by Non-inv NCT06391346 | Ulrich Rother | N/A |
| Unknown | Treatment of Complex Femoropopliteal Artery Lesions Using Drug-coated PTA Balloon NCT05616520 | Xuanwu Hospital, Beijing | — |
| Recruiting | MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology NCT06409949 | University of Nebraska | N/A |
| Recruiting | Smart Flex Stent System for the Treatment Long Femoropopliteal Artery Lesions NCT05894863 | RenJi Hospital | N/A |
| Completed | A New Heat Therapy Device for Home-based Leg Heating in Patients With Lower-extremity Peripheral Artery Diseas NCT05335161 | Purdue University | Phase 1 |
| Completed | Evaluation of Standard of Care Practices, Procedural Outcomes and In-hospital Complications of Peripheral Endo NCT05831319 | Biotronik AG | — |
| Completed | Elevated Levels of Antibodies to Endotoxin Core in Hemodialysis Patients With Peripheral Artery Disease NCT05752968 | Tungs' Taichung Metroharbour Hospital | — |
| Unknown | Safety and Efficacy of the QBX Peripheral Balloon Expandable Stent System in Peripheral Artery Disease (PAD) NCT05799131 | QualiMed Innovative Medizinprodukte GmbH | — |
| Unknown | Endovascular Treatment of Primary Common FEmoral Artery atheroSclerotic Disease wiTh IntraVAscular Litothripsy NCT05821829 | University of Pisa | — |
| Recruiting | Impact of Stress on Cardiovascular Events in Patients with Peripheral Arterial Disease NCT06887101 | University Hospital, Essen | — |
| Unknown | The Effects of Allicor on Patients After Revascularization Treatment During a Year NCT05813171 | Institute for Atherosclerosis Research, Russia | Phase 4 |
| Recruiting | Pounce™ Thrombectomy System Retrospective Registry NCT05868161 | SurModics, Inc. | — |
| Unknown | Outpatient Hospitalization of Unaccompanied Patients at Home for Endovascular Treatment of Peripheral Arterial NCT05756491 | Fondation Hôpital Saint-Joseph | N/A |
| Active Not Recruiting | The PORTuguese Registry of Supera Supported Femoral-Fopliteal Revascularization (SupPORT Registry) NCT06416644 | Hospital do Divino Espírito Santo de Ponta Delgada | N/A |
| Terminated | Tack Optimized Balloon Angioplasty Post-Market Study NCT05361967 | Spectranetics Corporation | — |
| Unknown | The IMPACT PAD Study NCT05035771 | Mid and South Essex NHS Foundation Trust | N/A |
| Withdrawn | Effect of Switching From Cigarette Smoking to THS on Systemic Endothelial Function in Subjects With Establishe NCT05566678 | Philip Morris Products S.A. | N/A |
| Terminated | Shockwave ®S4 Catheter IVL to Treat Infrapopliteal Calcified Stenoses and/or Occlusions in CLTI Patients (LEGA NCT05755412 | EndoCore Lab s.r.l. | — |
| Completed | A Non-significant Risk Clinical Study to Assess Perfusion Changes With Application of a TUS for Patients With NCT05100745 | Vibrato Medical, Inc. | N/A |
| Active Not Recruiting | Evaluate the Efficacy and Safety of the Cilostazol-coated BioMimics 3D Stent System in Patients with Periphera NCT05759819 | Otsuka Medical Devices Co., Ltd. Japan | N/A |
| Unknown | Gut Microbiota in Patients With Peripheral Arterial Disease and Chronic Limb-threatening Ischemia NCT05757297 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |
| Completed | Comparing BlueDop Vascular Expert to Ankle-Brachial Index in the Identification of Peripheral Vascular Disease NCT06436001 | Dakota Vascular | — |
| Recruiting | Carnosine for Peripheral Arterial Disease Patients NCT05371145 | Shahid Baba | Phase 1 / Phase 2 |
| Recruiting | High-intensity Intervals Versus Low-to-moderate-intensity Exercise Training in Patients With PAD NCT05612945 | Centre Hospitalier Universitaire Vaudois | N/A |
| Completed | Feasibility Study to Evaluate Therapeutic Ultrasound (TUS) to Acutely Increase the Perfusion in Peripheral Art NCT05888740 | Vibrato Medical, Inc. | N/A |
| Completed | To Investigate the Effect of Far-infrared Radiation on Lower Extremity Acupoints on the Blood Circulation of L NCT05822960 | National Taiwan University Hospital | N/A |
| Unknown | Analysis of Arterial Waveforms and Oxygen Pressure During Supervised Exercise for Peripheral Artery Disease NCT05818046 | University Hospital, Caen | N/A |
| Recruiting | Multi-modal Quantitative Imaging of the Skin NCT06989216 | HJN Sverige AB/Neko Health | — |
| Unknown | The Inperia Advance Post-Market Retrospective Study NCT05622084 | CID S.p.A. | — |
| Recruiting | Non-invasive Imaging for In-vivo Quantification of Skin Composition and Structure NCT06976073 | HJN Sverige AB/Neko Health | — |
| Unknown | The Cre8™ BTK Post Market Clinical Follow-up Study NCT05616156 | CID S.p.A. | — |
| Completed | Assessing Impacts of Static Magnetic Fields on Peripheral Pulses and Skin Blood Flow NCT04539704 | Nova Southeastern University | N/A |
| Unknown | The Isthmus Logic Post Market Clinical Follow-up Study NCT05616143 | CID S.p.A. | — |
| Completed | BOLT Lithotripsy RESTORE ATK Trial NCT05662787 | Bolt Medical | N/A |
| Completed | Evaluate Safety and Efficacy of Pronavi Microcatheter for Use in Endovascular Interventions NCT05747287 | BrosMed Medical Co., Ltd | N/A |
| Completed | A Non-significant Risk Clinical Study of Therapeutic Ultrasound for Patients With Diabetic Foot Ulcers. NCT05145439 | Vibrato Medical, Inc. | N/A |
| Completed | A Study to Compare the Effects of Sarpogrelate Sustained Release /Aspirin Combination Therapy Versus Aspirin o NCT05730621 | Yuhan Corporation | Phase 4 |
| Active Not Recruiting | Combined Treatment for Non-Healing Wounds in Chronic Lower Extremity Arterial Disease: a Comparative Study NCT06724276 | Tulip Medicine | N/A |
| Unknown | Effect of Anticoagulant Drug Intervention on Postoperative MALE and MACE in Patients With PAD NCT05852197 | First Affiliated Hospital of Zhejiang University | — |
| Unknown | Debulking Atherectomy Versus Stent Angioplasty for Limb Ischaemia of Diabetic Lower Limb Atherosclerosis-occlu NCT05670171 | Xuanwu Hospital, Beijing | N/A |
| Withdrawn | Mind Body Program for Vascular Disease NCT05757752 | Yale University | N/A |
| Unknown | Ultrasound Cavitation Therapy for CLI NCT05749250 | University of Virginia | N/A |
| Completed | Sarcopenia and Peripheral Artery Disease With Chronic Limb Threatening Ischemia NCT07037979 | Fudan University | — |
| Unknown | To Verify the Efficacy and Safety of Rapamycin Coated Peripheral Balloon Catheter in the Treatment of Femoral NCT05662618 | Shanghai Bomaian Medical Technology Co., Ltd | N/A |
| Recruiting | PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening I NCT05313165 | LimFlow, Inc. | N/A |
| Unknown | Pain and Hemodynamics in Peripheral Arterial Disease: Response to Pulsed Electromagnetic Treatment NCT06252181 | Ahram Canadian University | N/A |
| Recruiting | A ProspeCtive mUlticenteR Investigation on RENzar Stent Safety and Efficacy in the Treatment of Patients With NCT05701293 | Azienda Ospedaliera Universitaria Senese | — |
| Active Not Recruiting | SELUTION4SFA Trial NCT05132361 | M.A. Med Alliance S.A. | N/A |
| Unknown | Clinical Study of Endovascular Interventional Surgical Instrument Control System and Related Consumables in Lo NCT05625711 | Shanghai Operation Robot Co., Ltd. | N/A |
| Completed | A Usability Study of a Tele-health Service for Patients With Peripheral Arterial Disease. NCT05619835 | Medical University of Graz | — |
| Unknown | Mitochondrial Function in Peripheral Arterial Disease NCT05644158 | Medical University Innsbruck | N/A |
| Unknown | The Safety and Efficacy of the Suture-Mediated Closure System NCT05841836 | Zhejiang Zylox Medical Device Co., Ltd. | N/A |
| Completed | A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascul NCT05358353 | ReFlow Medical, Inc. | N/A |
| Unknown | Evaluation of Tissue Perfusion in Peripheral Arterial Disease (EVTI-PAD) NCT05570019 | Medical University Innsbruck | — |
| Completed | Using KomPas+ in the Treatment of Patients With Intermittent Claudication NCT05232474 | Radboud University Medical Center | N/A |
| Unknown | Novel Blood Biomarker for Peripheral Arterial Disease NCT05596136 | Unity Health Toronto | N/A |
| Unknown | Personalised Antiplatelet Therapy for Patients With Symptomatic Peripheral Arterial Disease NCT06047002 | University of Leicester | — |
| Unknown | Selution Sirolimus-eluting Balloon for Internal Pudendal-penile Artery Disease-related Erectile Dysfunction NCT05362994 | National Taiwan University Hospital | N/A |
| Completed | BOLT Lithotripsy RESTORE BTK Trial NCT05535907 | Bolt Medical | N/A |
| Completed | Effect of Acute Cardiovascular Disease on Microbiome NCT05456802 | University Hospital, Essen | — |
| Completed | Study of BD Sirolimus Drug Coated Catheter for Treatment of Femoropopliteal Arteries NCT05556681 | C. R. Bard | N/A |
| Unknown | Outcomes of Rivaroxaban and Aspirin in PAD After Endovascular Revascularization NCT05308030 | Assiut University | EARLY_Phase 1 |
| Completed | An Investigator Initiated Trial to Evaluate the Safety and Feasibility of the DyNETIC-35 Stent for Iliac Lesio NCT05372952 | Klinikum Arnsberg | — |
| Completed | Shockwave IVL + DES NCT05291247 | Marc Bosiers, MD | — |
| Active Not Recruiting | Impact of the Genetic Background as a Risk Factor for Atherosclerotic Cardiovascular Disease in the Brazilian NCT05515653 | Hospital Alemão Oswaldo Cruz | — |
| Completed | The Effect of Ischemic Conditioning on Strength and Ambulation in Subjects with PAD NCT04937179 | University of Illinois at Chicago | N/A |
| Withdrawn | Acute Effects of Leg Heating on Skeletal Muscle Blood Flow NCT03763357 | Indiana University | N/A |
| Completed | Evaluation of Safety and Efficacy of the S.M.A.R.T. RADIANZ™ Vascular Stent System in the Treatment of Iliac a NCT05399680 | Cordis US Corp. | N/A |
| Unknown | POWER: Pulse Intravascular Lithotripsy (Pulse IVL) to Open Vessels With Calcific Walls and Enhance Vascular Co NCT05192473 | Amplitude Vascular Systems, Inc. | N/A |
| Unknown | Calf Muscle Perfusion in Patients With Intermittent Claudication by Non-invasive MSOT NCT05373927 | Ulrich Rother | — |
| Active Not Recruiting | Belgian Study to Assess the Efficacy and Safety of the RESTORER Iliac Stent for Treatment of Aorto-iliac Lesio NCT05293002 | ID3 Medical | N/A |
| Unknown | Mesh Stents Study in ILIAC Complex Lesions (IMS-Study) NCT05377775 | Medical University of Warsaw | N/A |
| Completed | Acute Responses to Arm-Crank Exercise on Cardiovascular Function of Patients With Peripheral Artery Disease NCT05611021 | University of Nove de Julho | N/A |
| Active Not Recruiting | SIGNATURE Study : DCB (Legflow) vs POBA in Fempop Arteries NCT04971772 | Cardionovum GmbH | — |
| Completed | PMCF Study for Peripheral Arteries Above the Knee (ATK) NCT05312580 | Cordis US Corp. | — |
| Unknown | The Effect of Thermal Blanket After Peripheral Artery Surgery NCT06310928 | Saglik Bilimleri Universitesi | N/A |
| Recruiting | SELUTION4BTK Trial NCT05055297 | M.A. Med Alliance S.A. | N/A |
| Completed | The Use of HOVR Technology for Assessment of Blood Associated Parameters NCT05921461 | Votis Subdermal Imaging Technologies LTD | — |
| Withdrawn | Assessment of Superficial Femoral Artery Lesions With FFR From the ACIST Navvus® Catheter NCT05079906 | Acist Medical Systems | N/A |
| Active Not Recruiting | Safety and Effectiveness Evaluation of iCover Covered Stent for the Treatment of the Aorto-iliac Occlusive Dis NCT05192616 | iVascular S.L.U. | — |
| Completed | The Impact of Factor Xa Inhibition on Thrombosis, Platelet Activation, and Endothelial Function in Peripheral NCT05009862 | Vanderbilt University Medical Center | Phase 4 |
| Unknown | Vascular Effects Through Sirolimus vs. Paclitaxel DCB Implantation NCT05450042 | University Hospital, Essen | N/A |
| Completed | Prospective, Multi-center, Single-arm Study of the Auryon Laser System for Treatment of Below-the-Knee (BTK) A NCT05284240 | Midwest Cardiovascular Research Foundation | N/A |
| Completed | Mini S Feasibility Study With Shockwave Medical Mini S Peripheral IVL System NCT05058456 | Shockwave Medical, Inc. | N/A |
| Completed | Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With Diabetes NCT05009602 | Imperial College London | — |
| Unknown | Clinical Testing Study in Peripheral Arterial Disease NCT05243992 | Perfusio Corp. | — |
| Unknown | Calf Muscle Perfusion in Patients With Intermittent Claudication by 3D-reconstruction of MSOT (MSOT_IC_3D) NCT05773534 | Ulrich Rother | — |
| Completed | Periodontal Status and TMAO Levels in Peripheral Artery Disease NCT07449546 | Ankara University | — |
| Completed | Telehealth Exercise Training in Peripheral Arterial Disease - TEXT-PAD NCT05260567 | Northumbria University | N/A |
| Terminated | Exoskeleton Variability Optimization NCT04338815 | University of Nebraska | N/A |
| Unknown | Innova Breeze®-Based Roadmap for Peripheral Arterial Disease NCT05189522 | Fondation Hôpital Saint-Joseph | N/A |
| Completed | A Study on the Phenomenon of Remote Ischaemic Preconditioning in Patients With Peripheral Artery Disease NCT05084066 | Tartu University Hospital | N/A |
| Withdrawn | ACHIEVE GRX Registry NCT04513613 | Corindus Inc. | — |
| Completed | Aortoiliac Stenosis in Kidney Transplantation NCT06020534 | Erasmus Medical Center | — |
| Terminated | HORIZON Prospective Clinical Investigation NCT05234164 | Qmedics AG | N/A |
| Recruiting | CRUSH PAD: Real-world Outcomes Following Use of Shockwave Intravascular Lithotripsy (IVL) Technology in Calcif NCT05145478 | Yale University | — |
| Withdrawn | Pivotal Study of the Medtronic Axys EX Rotational Atherectomy System NCT04282161 | Medtronic Endovascular | N/A |
| Unknown | Pilot Study of Topographic Imaging of the Calf Muscle in Patients With PAD Using 3D Reconstruction of MSOT Ima NCT05110677 | University Hospital Erlangen | — |
| Unknown | Remote Monitoring of Home Exercise in Peripheral Arterial Disease NCT05209724 | Dallas VA Medical Center | N/A |
| Completed | Moderate Intensity Functional Training as Adjuvant Treatment in Patients With Peripheral Arterial Disease NCT05126680 | European University Miguel de Cervantes | N/A |
| Unknown | Serranator Recoil Study NCT05161039 | Cagent Vascular LLC | N/A |
| Completed | Clinical Evaluation of the BlueDop Vascular Expert for Assessing Peripheral Arterial Disease NCT05073510 | BlueDop Medical LTD | — |
| Completed | Integrating Fall Prevention Balance Exercises Into a Program for Older Adults With Peripheral Artery Disease ( NCT05090774 | University of Minnesota | N/A |
| Unknown | Preliminary Tissue Monitoring During Endovascular Intervention Study NCT04956523 | Pedra Technology, PTE LTD | — |
| Completed | Effects of aSPIrin Versus Aspirin Plus Low-dose RIvaroxaban on Carotid aTherosclerotic Plaque Inflammation NCT05797376 | Asan Medical Center | Phase 4 |
| Recruiting | Study of the R3 Vascular Drug-Eluting Bioresorbable Scaffold in Treating Below the Knee Arterial Disease NCT04912323 | R3 Vascular Inc. | N/A |
| Unknown | Promus PREMIER Below The Knee Registry NCT05054764 | Sengkang General Hospital | — |
| Active Not Recruiting | SCOPE-CLI: Shifting Care and Outcomes for Patients With Endangered Limbs NCT04710563 | Yale University | — |
| Unknown | Clinical Trial of C-Wave™ Peripheral Lithoclasty System Catheter System NCT05435716 | Suzhou Zhonghui Medical Technology Co., Ltd. | N/A |
| Not Yet Recruiting | Intermediate and Long-term Efficacy of Endovascular Treatment for TASC C&D Aortoiliac Occlusive Disease NCT04966767 | Shanghai Zhongshan Hospital | — |
| Completed | Safety and Performance of POLYTHESE® Vascular Prosthesis NCT05516043 | Perouse Medical | — |
| Unknown | SOLUTION Trial in China NCT05434676 | Genesis Medtech Corporation | N/A |
| Recruiting | The Frequency of Peripheral Arterial Disease in Patients with Deep Vein Thrombosis of the Lower Limbs NCT06806540 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Unknown | PAD Screening Study NCT05584072 | Chinese University of Hong Kong | — |
| Unknown | Revascularization of Total or Sub-total Occluded Peripheral Arteries With ByCross® Device. Post Market Clinica NCT05110079 | Taryag Medical Ltd. | — |
| Unknown | REmotely Supervised Exercise Therapy Trial 2 NCT04925219 | Mid and South Essex NHS Foundation Trust | N/A |
| Unknown | SOLARIS Peripheral PMCF Trial NCT04299906 | Dr. Sabrina Overhagen | N/A |
| Recruiting | Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk NCT04774159 | Population Health Research Institute | Phase 3 |
| Suspended | AndraValvulotome Post-Market Study NCT04815473 | Andramed GmbH | N/A |
| Unknown | The Biomimetic Stent and Vascular Functions Study NCT05447052 | University Hospital, Essen | N/A |
| Completed | Blood Flow Restricted Resistance Training in Peripheral Arterial Disease NCT04890275 | Sheffield Hallam University | N/A |
| Recruiting | This Study is a Prospective, Multi-center, Real World, Observational Study, Which Aims at Evaluating Intermedi NCT05391815 | Shanghai Zhongshan Hospital | — |
| Completed | Thrombospondin-4 Levels and Peripheral Arterial Disease in Hemodialysis Patients NCT04735562 | Tungs' Taichung Metroharbour Hospital | — |
| Completed | A Real-world Study to Evaluate the Primary Patency and Freedom From TLR of Endovascular Treatment in TOSAKA II NCT04801004 | Shanghai Zhongshan Hospital | — |
| Unknown | Personalised Activity Plan for BREAKing UP Sitting Time in Patients With Peripheral Arterial Disease and Inter NCT04572737 | University of Leicester | N/A |
| Completed | Medical Compression in Patients With Chronic Wound and Peripheral Arterial Disease NCT04829812 | University Hospital, Montpellier | — |
| Unknown | Influence of Rivaroxaban for Intermittent Claudication and Exercise Tolerance in Patients With Symptomatic PAD NCT04305028 | Poznan University of Medical Sciences | — |
| Unknown | Genotype-guided Strategy for Antithrombotic Treatment in Peripheral Arterial Disease. NCT04619927 | Radboud University Medical Center | Phase 4 |
| Unknown | ARTPERfit Clinical Trial. NCT04578990 | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | N/A |
| Unknown | Validation of the VascuQoL-6 Questionnaire to Assess ePROM After Revascularization for Lower Limb Peripheral A NCT04709107 | Kantonsspital Aarau | — |
| Unknown | Tissue Monitoring During Endovascular Intervention NCT04744870 | Pedra Technology, PTE LTD | — |
| Terminated | MyPADMGT Support of Out-Patients With Peripheral Arterial Disease NCT04228549 | McMaster University | N/A |
| Completed | Disrupt PAD+ Study With the Shockwave Medical M5+ Peripheral IVL System NCT04585763 | Shockwave Medical, Inc. | N/A |
| Completed | AngioSafe Peripheral CTO Crossing System Study (RESTOR-1 Study) NCT04663867 | AngioSafe, Inc. | N/A |
| Unknown | EFFECT OF AEROBIC TRAINING VERSUS MYOFACIAL RELEASE ON CLAUDICATION AMONG PREPHERAIL ARTERAIL INSUFFIECENCY PA NCT04734600 | ola mohamed elsayed mostafa elgohary | N/A |
| Completed | Liraglutide and Peripheral Artery Disease NCT04881110 | University of Campania Luigi Vanvitelli | Phase 4 |
| Unknown | Adapted Physical Activity in Patients With Lower Limb Peripheral Arterial Disease NCT04800276 | Centre Hospitalier le Mans | N/A |
| Recruiting | Assessment of the Utility of the Pantheris Small Vessel (SV) System NCT04793581 | Avinger, Inc. | N/A |
| Completed | Correlation Between Selected Haematological and Doppler Ultrasonic Parameters in Peripheral Arterial Diseased NCT04830254 | Cairo University | N/A |
| Recruiting | European All-comers' Multicentric Prospective REGISTRY on LUMINOR© Drug Eluting Balloon in the Superficial Fem NCT04743180 | iVascular S.L.U. | — |
| Completed | Education and Management of PAD in Primary Care NCT04342481 | University of Leicester | — |
| Unknown | MIMICS-3D-USA Registry Study NCT04640597 | Veryan Medical Ltd. | — |
| Unknown | Shockwave: Disruption for A Better Fit NCT05147363 | Cardiovascular Institute of the South Clinical Research Corporation | — |
| Unknown | Perfusion Assessment Using BOLD MRI and PBV in Endovascular Treatment of Peripheral Arterial Occlusive Disease NCT05045365 | Peking Union Medical College Hospital | — |
| Unknown | FGF-1 for Intramuscular Injection for the Treatment of Peripheral Arterial Disease NCT00424866 | CardioVascular BioTherapeutics, Inc. | Phase 1 / Phase 2 |
| Completed | Real-World Safety Analysis of Paclitaxel Devices Used for the Treatment of Peripheral Arterial Disease NCT04647643 | Lahey Clinic | — |
| Completed | Muscle Perfusion in Patients With PAD by Non-invasive MSOT NCT04641091 | University Hospital Erlangen | — |
| Active Not Recruiting | Major Adverse Limb Events in Patients With Femoro-popliteal and Below-the-knee Peripheral Arterial Disease Tre NCT04238546 | Nils Kucher | N/A |
| Unknown | Personalizing Aspirin Therapy in Peripheral Arterial Disease Patients NCT04269863 | Unity Health Toronto | N/A |
| Unknown | Functional MRI of the Lower Extremities NCT03423316 | Massachusetts General Hospital | N/A |
| Completed | A Research Study to Compare a Medicine Called Semaglutide Against Placebo in People With Peripheral Arterial D NCT04560998 | Novo Nordisk A/S | Phase 3 |
| Unknown | NEtwork to Control ATherothrombosis (NEAT Registry) NCT04677725 | Hospital do Coracao | — |
| Completed | DCB Outcomes After Plain or Scoring Balloon for Vessel Preparation in Patients With Femoropopliteal Arterial D NCT07136883 | Marc Sirvent | N/A |
| Completed | AbsorbaSeal (ABS 5.6.7) Vascular Closure Device Trial NCT04635501 | ID3 Medical | N/A |
| Recruiting | The Efemoral Vascular Scaffold System (EVSS) for the Treatment of Patients With Symptomatic Peripheral Vascula NCT04584632 | Efemoral Medical, Inc. | N/A |
| Active Not Recruiting | A Genomic Approach for Clopidogrel in Caribbean Hispanics NCT03419325 | University of Puerto Rico | EARLY_Phase 1 |
| Completed | The Role of HSP90 in Peripheral Vascular Lesions of Diabetic Atherosclerosis NCT04787770 | Nanfang Hospital, Southern Medical University | — |
| Withdrawn | The Merit WRAPSODY™ Endovascular Stent Graft for Treatment of Iliac Artery Occlusive Disease NCT03994185 | Merit Medical Systems, Inc. | N/A |
| Completed | Arterial Dissections After Angioplasty by Long vs Short Time of Balloon Inflation: the Randomized Controlled T NCT04442802 | Dumitru Casian | N/A |
| Unknown | Post-Market Registry of AURYON™ Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery D NCT04229563 | Angiodynamics, Inc. | — |
| Completed | Exoskeleton Footwear to Improve Walking NCT04337554 | VA Office of Research and Development | — |
| Unknown | The CLI-AMP Registry NCT04427124 | Hendrick Medical Center | — |
| Unknown | Comparison of 3 Ultrasonic Techniques for Measuring the Systolic Pressure Index NCT04440072 | University Hospital, Caen | — |
| Completed | Safety Assessment of Femoropopliteal Endovascular Treatment With PAclitaxel-coated Devices (SAFE-PAD Study) NCT04496544 | Beth Israel Deaconess Medical Center | — |
| Completed | Safety and Feasibility of Surmodics SUNDANCE™ Drug Coated Balloon NCT04107298 | SurModics, Inc. | N/A |
| Completed | Observational Study to Assess Transradial Access for Treatment in the Lower Extremities. NCT04371861 | Terumo Medical Corporation | — |
| Completed | Natural Vascular Scaffold (NVS) Therapy for Treatment of Atherosclerotic Lesions (Activate I) NCT04188262 | Alucent Biomedical | Phase 1 |
| Completed | Creatine Use and Muscle Stretching in Peripheral Artery Disease NCT04471792 | Florida State University | Phase 2 |
| Recruiting | A Study Evaluating the Endovascular Treatment of Subjects with Stenotic or Restenotic Lesions of the Common Fe NCT04349657 | ID3 Medical | N/A |
| Unknown | Cysteinyl Leukotriene Antagonist in Atherosclerosis Inhibition in Patients After Endovascular Treatment Due to NCT04277702 | Jagiellonian University | Phase 3 |
| Unknown | Cost-utility Analysis, Cost-effectiveness Analysis, Budget Impact Analysis NCT04283565 | University Hospital, Tours | N/A |
| Completed | Digital Variance Angiography in Diagnostic Angiographies for Effective Radiation Dose Reduction NCT04343196 | Kinepict Health Ltd. | N/A |
| Active Not Recruiting | A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the NCT03477604 | Micro Medical Solution, Inc. | N/A |
| Completed | Implementation of ABI and WIfI in Rural Health Clinics NCT04337723 | University of California, Davis | N/A |
| Completed | Implementation of Telemedicine for Patient With Lower Extremity Wounds NCT04440839 | University of California, Davis | N/A |
| Unknown | Effects of Combined Aerobic and Resistance Training in Patients With Intermittent Claudication NCT04302571 | University Of Perugia | N/A |
| Completed | Ultrasonic Perfusion Estimation in Calf Muscle NCT04755335 | Mayo Clinic | — |
| Completed | A Prospective, Multicenter Atherectomy Study Showing Luminal Gain in Subjects With Peripheral Vascular Blockag NCT04241224 | Ra Medical Systems | N/A |
| Active Not Recruiting | A Trial to Evaluate the Safety and Efficacy of the Passeo-18 Lux Drug-coated Balloon of Biotronik in the Treat NCT03884257 | ID3 Medical | N/A |
| Completed | A Study of the TEmporary Spur StEnt System for the Treatment of Lesions Located in the InfraPoplitEal ARteries NCT04162418 | ReFlow Medical, Inc. | N/A |
| Withdrawn | Blood Flow Changes in Femoral-popliteal Bypass Grafts After Neuromuscular Electrical Stimulation (NMES). NCT04109287 | Imperial College Healthcare NHS Trust | N/A |
| Unknown | The Effects of Oral Inorganic Nitrate Supplementation on Lower Limb Perfusion During Exercise in Patients With NCT05036213 | University of Virginia | Phase 1 |
| Completed | Intermittent Pneumatic Compression to Improve Revascularization Outcome NCT04250675 | Indiana University | N/A |
| Recruiting | EMPOWER-1: A Multi-site Clinical Cohort Research Study to Reduce Health Inequality NCT03987633 | Future Genetics Limited | — |
| Recruiting | Peripheral Extreme Revascularization in "No-option" Patiens With Chronic Limb Threatening Ischemia NCT06277362 | EndoCore Lab s.r.l. | — |
| Unknown | Hypoxic Exercise in Lower Extremity Artery Disease NCT03506607 | Centre Hospitalier Universitaire Vaudois | N/A |
| Completed | PAD Awareness Study NCT05552079 | Chinese University of Hong Kong | — |
| Unknown | Revascularization of Stenosed Vessels Using Optimized Treatment of Rejuveinix for Reversing Endothelial Dysfun NCT03041259 | Reven Pharmaceuticals, Inc. | Phase 1 / Phase 2 |
| Unknown | Ultrasound Evaluation of Lower Extremity Arteries After Topical Nitroglycerin Administration NCT04155476 | Deborah Heart and Lung Center | EARLY_Phase 1 |
| Completed | Gremlin-1 and Wagner Classification: Potential Biomarker for Amputation in Diabetic Foot Patients NCT06753604 | Seyma Acik | — |
| Completed | The PRELUDE BTK Study NCT03693963 | Cagent Vascular LLC | N/A |
| Unknown | PROMISE II: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Is NCT03970538 | LimFlow, Inc. | N/A |
| Unknown | LegDeb2 Global Registry for Use of Legflow in Peripheral Arteries NCT04175197 | Federico II University | — |
| Active Not Recruiting | An All-Comers Observational Study of the MicroStent™ Peripheral Vascular Stent System in Subjects With Periphe NCT04110327 | Micro Medical Solution, Inc. | — |
| Active Not Recruiting | TORUS 2 IDE Clinical Study NCT04130737 | Endologix | N/A |
| Terminated | ChampioNIR® SFA Stent EFS Study NCT03775226 | Medinol Ltd. | N/A |
| Unknown | Serum Levels of Klotho as a Possible Biomarker of Peripheral Artery Disease NCT05757271 | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | — |