Clinical Trials Directory

Trials / Recruiting

RecruitingNCT07223593

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

A Study to Investigate the Efficacy and Safety of Orforglipron Once Daily in Participants With Peripheral Artery Disease: A Randomized, Double-Blind, Placebo Controlled Trial

Status
Recruiting
Phase
Phase 3
Study type
Interventional
Enrollment
1,205 (estimated)
Sponsor
Eli Lilly and Company · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the effect and safety of orforglipron once daily in participants with Fontaine II peripheral arterial disease (PAD). Participation in the study will last about 58 weeks.

Conditions

Interventions

TypeNameDescription
DRUGOrforglipronAdministered orally
DRUGPlaceboAdministered orally

Timeline

Start date
2025-10-31
Primary completion
2028-06-01
Completion
2028-06-01
First posted
2025-11-03
Last updated
2026-04-17

Locations

138 sites across 16 countries: United States, Argentina, Australia, Brazil, Canada, China, France, India, Japan, Netherlands, Poland, Puerto Rico, Slovakia, South Korea, Taiwan, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT07223593. Inclusion in this directory is not an endorsement.