NCT06275113

BRING-UP Prevention

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 6,000 (estimated)
• Sponsor: Heart Care Foundation · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this observational study is to assess in patients with a documented athero-thrombotic event: coronary artery disease (CAD), cerebrovascular disease (CVD), peripheral artery disease (PAD): * the level of adherence to guideline recommendations with the assumption to improve the rate of patients at goal for cholesterol levels. * the level of adherence to guideline recommendations and the rate of patients at goal for the other relevant and modifiable risk factors for cardiovascular event recurrence.

Detailed description

Observational, prospective, multicenter study conducted in a large, representative sample of Italian cardiology centers. Phases: 1. First educational intervention to discuss the recommendations of guidelines for secondary prevention strategies. 2. Data collection for 3 months or up to 30 consecutive patients in patients with documented CAD/CVD/PAD on a web Case Record Form (CRF) generating warning on the most relevant guideline recommendations, and, when guidelines are not followed, asking the reason for non-adherence. 3. Evaluation of the primary and secondary end-points of the study at 6 months after enrollment. 4. Second educational intervention to share the results of the first enrollment period of the study focusing the attention on existing gaps between guidelines recommendations and clinical practice. 5. New data collection for 3 months or up to 30 consecutive patients in patients with documented CAD/CVD/PAD on a web CRF generating warning on the most relevant guideline recommendations, and, when guidelines are not followed, asking the reason for non-adherence. 6. Additional evaluation of the primary and secondary end-points of the study at 6 months after enrollment. 7. 12-month follow-up for all patients included in both enrolment phases.

Conditions

• Ischemic Heart Disease
• Cerebrovascular Disorders
• Peripheral Arterial Disease

Timeline

• Start date: 2023-09-15
• Primary completion: 2026-06-30
• Completion: 2026-06-30
• First posted: 2024-02-23
• Last updated: 2024-02-23

Locations

196 sites across 1 country: Italy