Trials / Completed
CompletedNCT06702202
Effect of Subarachnoid Block and Femoropopliteal Block to Limb Perfusion in PAD Patients
Comparison of the Effect of Subarachnoid Block and Femoropopliteal Block to Limb Perfusion in Patients with Peripheral Arterial Disease
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 16 (actual)
- Sponsor
- Indonesia University · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
This pilot study investigates the effects of femoropopliteal and subarachnoid nerve blocks on tissue oxygen saturation (StO2) in patients with Peripheral Arterial Disease (PAD) during lower limb surgeries. Using Near-Infrared Spectroscopy (NIRS), the study compares changes in StO2 post-block. Although no significant differences were found between the two block types at most time points, subarachnoid blocks generally led to higher StO2 increases compared to femoropopliteal blocks, with significant differences observed at 5 and 15 minutes post-block.
Detailed description
This pilot study explored the impact of femoropopliteal and subarachnoid nerve blocks on tissue oxygen saturation (StO2) in patients with Peripheral Arterial Disease (PAD) during lower limb surgeries, using Near-Infrared Spectroscopy (NIRS) for non-invasive monitoring. The study compared StO2 changes at baseline, 5, 15, and 30 minutes post-block in two groups: those receiving femoropopliteal blocks and those receiving subarachnoid blocks.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Mixture of local anesthetics | Marcaine® (bupivacaine HCl) 0,5% and Xylocaine® (Lidocaine HCL) 2% = 2:1 Given in Femoropopliteal block group (Group F) |
| DRUG | 0.5% hyperbaric bupivacaine | Given in Subarachnoid block group (Group S) |
Timeline
- Start date
- 2024-01-01
- Primary completion
- 2024-07-01
- Completion
- 2024-07-01
- First posted
- 2024-11-22
- Last updated
- 2024-11-22
Locations
1 site across 1 country: Indonesia
Source: ClinicalTrials.gov record NCT06702202. Inclusion in this directory is not an endorsement.