| Not Yet Recruiting | Periodontal Dressings in Non-Surgical Therapy NCT07472218 | Saglik Bilimleri Universitesi | N/A |
| Active Not Recruiting | Injectable PRF in Non-Surgical Periodontal Treatment NCT07375004 | Al-Mustansiriyah University | N/A |
| Not Yet Recruiting | Occlusal Load Distribution and Periodontal Status NCT07199062 | University of Bari Aldo Moro | — |
| Recruiting | Hyaluronic Acid and Octenidine Gel as an Adjunct to Non-surgical Periodontal Treatment NCT06522438 | Queen Mary University of London | N/A |
| Not Yet Recruiting | The Efficacy of Salvia Officinalis Gel in the Treatment of Periodontitis CLINICAL TRIAL NCT06900517 | University of Baghdad | N/A |
| Recruiting | Hyaluronic Acid and Polynucleotides for Supra-bony Defects NCT06309719 | Queen Mary University of London | N/A |
| Recruiting | Modified Widman Flap vs Fibre Retention Osseous Resective Surgery NCT06123000 | University of Florence | N/A |
| Completed | Efficacy of Locally Delivered Rosemary Extract Gel in Management of Periodontitis NCT06601608 | Ain Shams University | Phase 2 |
| Not Yet Recruiting | Evaluation of iPRF With Vit.D As an Adjunct to Non-Surgical Therapy in the Treatment of Stage III Periodontiti NCT06570200 | Cairo University | Phase 2 |
| Active Not Recruiting | The Proposed Study Aims to Investigate the Efficacy of Quercetin as an Adjunctive to Mechanical Debridement in NCT06982248 | Mansoura University | Phase 2 |
| Recruiting | Evaluation of 2%Bromelain Gel With 0.2%CHX Gel as Subgingival LDD Following SRP in Stage II/III and Grade B Pe NCT06505759 | Krishnadevaraya College of Dental Sciences & Hospital | Phase 1 |
| Not Yet Recruiting | Comparing Photodisinfection of Chitosan NP Enriched ICG Over ICG as Adjunct to OFD: RCT NCT06523244 | Krishnadevaraya College of Dental Sciences & Hospital | N/A |
| Recruiting | Effectiveness of SRP+ Lipo-curcumin Gel for the Treatment of Stage III Periodontitis. NCT06624241 | G. d'Annunzio University | N/A |
| Completed | Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice NCT06131021 | Rutgers, The State University of New Jersey | Phase 3 |
| Recruiting | Treatment Of Shallow Periodontal Pockets 4-6mm Using AIRFLOW Prophylaxis Master Device With Erythritol vs Manu NCT06351982 | Cairo University | N/A |
| Unknown | Chitosan Brushes vs Air-Abrasive Devices on Peri-implant Mucositis Treatment: A Randomized Clinical NCT06287957 | Istanbul University | N/A |
| Recruiting | Evaluation Of Nonsurgical Treatment Of Deep Periodontal Pockets (7-10mm) Using AIRFLOW® Prophylaxis Master Dev NCT06490679 | Cairo University | N/A |
| Completed | Comparative Evaluation of Bromelain-Quercetin Gel With Chlorhexidine Gel as Subgingival Local Drug Delivery Fo NCT06775392 | Krishnadevaraya College of Dental Sciences & Hospital | Phase 1 |
| Withdrawn | Inulin Supplementation During Sanative Therapy to Further Improve Periodontal Healing NCT04670133 | Brock University | N/A |
| Completed | Thyme Honey Mouthwash in Management of Periodontitis in Renal Patients NCT06129097 | British University In Egypt | N/A |
| Unknown | Clinical Efficacy of Saffron Mouth Rinse in Periodontitis Patients With Renal Disease NCT06235021 | British University In Egypt | N/A |
| Unknown | Local Delivery of Silk Fibroin and Chlorhexidine NCT06050863 | Krishnadevaraya College of Dental Sciences & Hospital | Phase 1 |
| Completed | The Proposed Study Aims to Investigate the Impact of Adjunctive Vitamin D Gel Application on Gingival Crevicul NCT06669026 | Mansoura University | Phase 2 |
| Completed | Electroacupuncture as an Adjunct to Non-Surgical Periodontal Therapy NCT06247007 | Didem OZKAL EMINOGLU | N/A |
| Enrolling By Invitation | Comparison of Gingival Flap Procedure Using Conventional Surgical Loupes vs. Videoscope for Visualization NCT05932017 | Texas A&M University | — |
| Completed | Amoxicillin Plus Metronidazole in Periodontal Maintenance NCT05934227 | Federal University of Minas Gerais | N/A |
| Unknown | Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets NCT06318247 | The Dental Hospital of Zhejiang University School of Medicine | N/A |
| Recruiting | Three Types of Papilla Incision in Periodontal Surgery NCT06428149 | Universidad de Murcia | N/A |
| Unknown | Treatment of Advanced Periodontitis With a Chitosan Brush and a Chitosan Gel NCT05773911 | Caspar Wohlfahrt | N/A |
| Unknown | Treatment of Intraosseous Periodontal Defects With Amelogenins NCT05315804 | Federico II University | N/A |
| Completed | Concentrated Platelet Rich Fibrin (C-PRF) as Adjunct to Non-surgical Periodontal Therapy NCT05958147 | Krishnadevaraya College of Dental Sciences & Hospital | Phase 1 |
| Unknown | Insulin Versus Hyaluronic Acid in Management of Periodontal Defects NCT05746676 | October University for Modern Sciences and Arts | Phase 3 |
| Completed | Glucosamine Sulphate Versus Ginger in Non-Surgical Periodontal Therapy NCT06200415 | Ain Shams University | Phase 2 |
| Completed | Efficacy of Locally Delivered Tea Tree Oil Gel as an Adjunct to Non-Surgical Periodontal Management NCT05803031 | Ain Shams University | N/A |
| Completed | PRF Therapy for Pocket Reduction NCT05908929 | Federico II University | N/A |
| Unknown | Evaluation of a New Technique for Periodontal Pocket Reduction in the Extraction of Wisdom Teeth NCT05722509 | Universidad Rey Juan Carlos | N/A |
| Completed | "Re-instrumentation vs Flap Surgery" NCT05460988 | University of Florence | N/A |
| Completed | Non-surgical Step 3 Periodontal Treatment With/Without Adjunctive Protocol - Pilot RCT. NCT06438354 | University of Witten/Herdecke | Phase 4 |
| Recruiting | Periodontal Granulation Tissue Preservation in Surgical Periodontitis Treatment NCT05533528 | Universidad de Murcia | N/A |
| Completed | Use of Ozone Gel as an Antimicrobial in Treatment of Periodontitis NCT05905445 | Ghufran Falih Hassan | Phase 1 |
| Completed | Treatment of Intraosseous Periodontal Defects With Hyaluronic Acid NCT05188898 | Federico II University | N/A |
| Unknown | The Efficacy of Autogenous Dentin Graft in Mandibular Wisdom Tooth Extraction NCT06073639 | University of Medicine and Pharmacy at Ho Chi Minh City | N/A |
| Completed | Periodontal Maintenance and the COVID-19 Pandemic NCT05125835 | Brock University | — |
| Completed | Photodynamic in Periodontal Treatment NCT05162417 | University of Sulaimani | N/A |
| Recruiting | Ozonized Olive Oil in the Treatment of Periodontal Pockets NCT06980675 | University of Bari | N/A |
| Completed | The Use of Submucosal Dexamethasone After Periodontal Surgery NCT06119893 | Yuzuncu Yil University | N/A |
| Recruiting | Comparing Different Timings for Periodontal Re-evaluation After Non-surgical Periodontal Therapy (NSPT) NCT05088746 | University of Parma | — |
| Completed | Periodontal Disease in Patients With Obstructive Sleep Apnea NCT04581798 | I.M. Sechenov First Moscow State Medical University | — |
| Completed | Placenta Extract Gel as a Periodontal Local Delivery Drug NCT06506539 | Suez Canal University | Phase 2 |
| Completed | Assessment Of Healing After Periodontal Flap Surgery With And Without The Use Of Placental Extracts NCT05936450 | Dr Prabhuji MLV | Phase 4 |
| Completed | Quantitation of Bacteria Associated With Severe Periodontitis by Real -Time PCR Following Application of Diode NCT05222737 | Alexandria University | Phase 2 / Phase 3 |
| Terminated | Predictors of Periodontal Outcomes Post-sanative Therapy NCT04639661 | Brock University | — |
| Completed | Different Autologous Products in The Treatment of Intrabony Defects NCT05941312 | Yuzuncu Yil University | N/A |
| Unknown | Evaluation of Two Different Grafting Techniques After Mandibular Impacted Third Molar Surgery NCT04366635 | Konya Necmettin Erbakan Üniversitesi | N/A |
| Unknown | Accuracy of Pulp Sensibility Test on Teeth With Deep Periodontal Pocket NCT04399135 | Qassim University | N/A |
| Unknown | Effect of Trait Anxiety in Women on Oral Health Status and Oral Health Care-Seeking Behavior NCT04274855 | Ain Shams University | — |
| Unknown | Bone Height and Extractions Study NCT03909568 | King's College London | N/A |
| Completed | Non-Incised Papillae Surgical Approach (NIPSA) With and Without Graft NCT04712630 | Universidad de Murcia | N/A |
| Recruiting | NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration NCT03997552 | Universidad de Murcia | N/A |
| Unknown | Lycopene vs Minocycline Hydrochloride as Adjunctive to Periodontal Treatment NCT03964935 | University of Baghdad | Phase 2 |
| Unknown | Clinical and Radiographic Evaluation of PPF With or Without NCHA Bone in Treatment of Intrabony Defects NCT03588507 | Cairo University | N/A |
| Completed | Periodontal Outcomes After Sanative Therapy NCT03649789 | Brock University | — |
| Completed | Autologous Fibrin Glue Application as an Adjunct to Nonsurgical Periodontal Treatment of Chronic Periodontitis NCT04082949 | Inonu University | EARLY_Phase 1 |
| Completed | Investigation of the Safety and Efficacy of Pocket-X Gel NCT03358251 | Tree of Life Pharma Ltd. | N/A |
| Completed | Effects of Polynucleotides and Hyaluronic Acid Based Subgingival Periodontal Pockets Re-instrumentation NCT05210686 | University of Roma La Sapienza | N/A |
| Completed | Effect of Dental Pulp Stem Cells and L-PRF After Impacted Third Molar Extraction NCT04641533 | Baskent University | N/A |
| Completed | Prevention of Mandibular Third Molar Extraction- Associated Periodontal Defects Using Platelet-Rich Fibrin NCT04033744 | University of Naples | N/A |
| Completed | Effect of Switching From Cigarette Smoking to the Use of IQOS on Periodontitis Treatment Outcome NCT03364751 | Philip Morris Products S.A. | N/A |
| Completed | Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study NCT05631600 | University of Zagreb | Phase 2 / Phase 3 |
| Completed | Treatment of Periodontal Intraosseous Defects NCT04542746 | Iorio Research and Dental Practice | N/A |
| Completed | Ultrasonic Versus Ultrasonic+ for Effective Sanative Therapy NCT03074565 | Brock University | N/A |
| Terminated | Antimicrobial Photodynamic Therapy on Periodontal Treatment and Salivary Status of Type 1 Diabetes Mellitus Pa NCT03102892 | University of Sao Paulo | N/A |
| Completed | Interaction Between Immune Cells and Bacteria Associated With Periodontitis NCT03225950 | University of Copenhagen | — |
| Completed | Dietary Intakes and Periodontal Health: A Follow-Up Study NCT03073174 | Brock University | — |
| Completed | Flavonoid Intake and Periodontal Healing NCT03073161 | Brock University | — |
| Completed | Antimicrobial Photodynamic Therapy in Patients With Periodontal Disease and Type 2 Diabetes Mellitus NCT05816941 | University of Ljubljana | N/A |
| Completed | Locally Injected Vit D as a Non-surgical Modality for Periodontal Regeneration of Infrabony Defects NCT03716765 | Cairo University | N/A |
| Completed | Evaluation of the Rinse With Chlorhexidine Plus Hyaluronic Acid Mouthwash in Periodontal Surgical Wound Healin NCT04345744 | University of Pisa | N/A |
| Completed | Periodontal Changes Following Mid Maxillary Distraction NCT03686761 | University of Alexandria | N/A |
| Completed | Evaluation of Endodontic Status on Periodontal Healing of Concomitant Endodontic Periodontal Lesions NCT02630173 | Postgraduate Institute of Dental Sciences Rohtak | N/A |
| Completed | Chlorhexidine Intracanal Medicament in Periodontal Healing in Concomitant Endo Perio Lesion With Communication NCT02627326 | Postgraduate Institute of Dental Sciences Rohtak | Phase 2 |
| Completed | Efficacy of Amoxicillin-metronidazole Compared to Clindamycin in Patients With Periodontitis and Diabetes NCT03374176 | Centro Universitario de Tonalá | Phase 3 |
| Completed | The Use of Erythritol Powder and Metronidazole Gel for the Non-surgical Treatment of Periodontitis NCT02023840 | Proed, Torino, Italy | Phase 4 |
| Completed | Dietary Intakes and Periodontal Outcomes After Sanative Therapy NCT02291835 | Brock University | — |
| Completed | Gingival Crevicular Fluid Bone Morphogenetic Protein - 2 Release Profile Following the Use of Perforated Membr NCT01860495 | Al-Azhar University | — |
| Completed | Effect of Photodynamic Therapy on Gingival Crevicular Cytokines in Periodontitis Patients NCT03453476 | National University of Singapore | N/A |
| Unknown | Periodontal Tissue Regeneration Using Autologous Periodontal Ligament Stem Cells NCT01357785 | Air Force Military Medical University, China | Phase 1 |
| Completed | Marginal Periosteal Pedicle Flap - Platelet Rich Fibrin Barriers in Treating Periodontal Intrabony Defects NCT02359539 | Al-Azhar University | Phase 2 |
| Completed | Undiagnosed Diabetes in a Dental Setting NCT01711385 | Columbia University | N/A |