Trials / Unknown
UnknownNCT06050863
Local Delivery of Silk Fibroin and Chlorhexidine
A Comparative Evaluation of Subgingivally Delivered Chlorhexidine, Silk Fibroin and Combination of Fibroin and Chlorhexidine as Local Drug Delivery in Periodontitis - A Randomized Control Trial
- Status
- Unknown
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 15 (estimated)
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital · Academic / Other
- Sex
- All
- Age
- 30 Years – 50 Years
- Healthy volunteers
- Accepted
Summary
The current study is a prospective randomised split mouth study to evaluate the effect of Silk fibroin as drug delivery system while simultaneously assessing the efficacy of silk fibroin in comparison to chlorhexidine.
Detailed description
Fifteen healthy individuals satisfying the inclusion and exclusion criteria were recruited for the study. A detailed, thorough medical and dental history was obtained and each patient was subjected to comprehensive clinical and radiological examination. All patients were informed about the nature of the study, procedure involved, potential benefits and risks associated with procedure and written informed consent were obtained from all patients.All the patients underwent scaling and root planing. Following randomization, the site will be assigned to one of the three study groups. 1. Group I (SRP+ Silk Fibroin) 2. Group II (SRP+ Chlorhexidine) 3. Group III (SRP+ Combination of Fibroin and Chlorhexidine) Periodotal pack was placed and patient was recalled after 21days, 1 month and 3 month for the follow up.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | silk fibroin | silk fibroin extracted from bombyx mori silk worm is processed in laboratory to form silk fibroin films |
| DRUG | Chlorhexidin | chlorhexidine is used |
| BIOLOGICAL | combination of silk fibroin and chlorhexidine | combination of silk fibroin and chlorhexidine is used |
Timeline
- Start date
- 2023-11-01
- Primary completion
- 2024-06-01
- Completion
- 2024-07-01
- First posted
- 2023-09-22
- Last updated
- 2023-09-22
Source: ClinicalTrials.gov record NCT06050863. Inclusion in this directory is not an endorsement.