NCT06982248

The Proposed Study Aims to Investigate the Efficacy of Quercetin as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis

Efficacy of Quercetin Loaded on Chitosan Nanoparticles Gel as an Adjunctive to Mechanical Debridement in Treatment of Periodontitis: Randomized Controlled Clinical Trial

• Status: Active Not Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Mansoura University · Academic / Other
• Sex: All
• Age: 25 Years – 55 Years
• Healthy volunteers: Accepted

Summary

the proposed study aims to investigate the effect of Quercetin in treatment of periodontitis patients

Detailed description

the proposed study aims to investigate the effect of Quercetin in treatment of periodontitis patients not having systemic diseases.the 2ry aim of study to estimate the neacular factor kabba B level in gingival crevicular fluids.

Conditions

• Periodontal Pocket

Interventions

Type	Name	Description
DRUG	NSP and chitosan nanoparticles gel loaded by quercetin	NSP and chitosan nanoparticles gel loaded by quercetin
DRUG	NSP and chitosan nanoparticles gel	NSP and chitosan nanoparticles gel
PROCEDURE	scaling and root planning	NSPT

Timeline

• Start date: 2024-08-15
• Primary completion: 2025-02-01
• Completion: 2025-06-01
• First posted: 2025-05-21
• Last updated: 2025-05-21

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated drug study