NCT06570200

Evaluation of iPRF With Vit.D As an Adjunct to Non-Surgical Therapy in the Treatment of Stage III Periodontitis

Evaluation of Injectable PRF With Vitamin D As an Adjunct to Non-Surgical Therapy in the Treatment of Stage III Periodontitis. A Randomized Controlled Clinical Trial

• Status: Not Yet Recruiting
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 45 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

a clinical trial will be made to investigate the effect of locally applied injectable prf (iPRF) plus vitamin D on the periodontal pockets in stage III periodontitis patients

Detailed description

in this clinical trial, the treatment of periodontal pockets in stage III periodontitis patients will be evaluated. the study participants will be divided in 3 groups: First group \>\> will be treated with professional mechanical plaque removal (PMPR) only. second group \>\> will be treated with PMPR + locally applied iPRF. Third group \>\> will be treated with PMPR + locally applied iPRF + vitamin D. Then the results will be compared after 6 months of the treatment (clinically and radiographically).

Conditions

• Periodontal Pocket

Interventions

Type	Name	Description
PROCEDURE	PMPR+iPRF	locally applied iPRF in the periodontal pocket
DRUG	PMPR+iPRF+Vit.D	locally applied iPRF plus vitamin D in the periodontal pocket
PROCEDURE	PMPR only	scaling and root planing only will be done for the periodontal pocket for the control group

Timeline

• Start date: 2024-10-01
• Primary completion: 2025-10-01
• Completion: 2026-02-01
• First posted: 2024-08-26
• Last updated: 2024-08-26