| Not Yet Recruiting | Impact of Exogenous Ketones on Sleep Apnea NCT06687655 | Johns Hopkins University | Phase 1 / Phase 2 |
| Not Yet Recruiting | Wearable Voice-Guided BBTi for Comorbid Insomnia and Sleep Apnea (COMISA) NCT07521319 | National Sun Yat-sen University | N/A |
| Not Yet Recruiting | Transcutaneous Electrical Stimulation in Patients With Obstructive Sleep Apnoea NCT07343362 | Zeus Sleep Ltd | N/A |
| Not Yet Recruiting | KPAP vs EPR for Efficacy NCT07530523 | SleepRes Inc. | N/A |
| Enrolling By Invitation | Myofunctional Therapy for Obstructive Sleep Apnea NCT07301125 | University of Minnesota | N/A |
| Not Yet Recruiting | KPAP vs EPR for Comfort NCT07530510 | SleepRes Inc. | N/A |
| Not Yet Recruiting | Start CPAP Therapy in Obstructive Sleep Apnea Patients After Atrial Fibrillation Ablation NCT07444372 | Beijing Anzhen Hospital | N/A |
| Not Yet Recruiting | Bi-lateral HGN Therapy in Real-World Patients -Post Approval Research Investigation NCT07331285 | Nyxoah Inc. | — |
| Not Yet Recruiting | Exploration of Current and New Technologies for Accuracy of Diagnosing OSA NCT07485582 | ResMed | — |
| Recruiting | Oro-myofunctional Characteristics and Obstructive Sleep Apnea in Infants With Down Syndrome NCT07195253 | Hospices Civils de Lyon | — |
| Recruiting | Tongue Muscular Assessment in Children With Sleep Disordered Breathing NCT07273019 | Hospices Civils de Lyon | N/A |
| Not Yet Recruiting | Validity and Reliability of the 6-Minute Pegboard and Ring Test (6PBRT) in Adults With Obstructive Sleep Apnea NCT07465874 | Mardin Artuklu University | — |
| Not Yet Recruiting | Prospective Evaluation of New Metrics to Assess Cardiovascular Remodeling in Obstructive Sleep Apnea NCT07427589 | University Hospital, Antwerp | — |
| Enrolling By Invitation | Validation and Usability Study of the SleepView+ Home Sleep Testing System for the Evaluation of Moderate to S NCT07476313 | Beacon Biosignals | — |
| Recruiting | Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea NCT07447011 | Cairo University | N/A |
| Not Yet Recruiting | Continuous Positive Airway Pressure, Arousability and Links to Mechanisms in Obstructive Sleep Apnea NCT07332442 | Yale University | Phase 3 |
| Active Not Recruiting | RPMO2 Oximeter Accuracy During Sleep 1 Trial NCT07397780 | ProSomnus Sleep Technologies | — |
| Recruiting | Obstructive Sleep Apnea Therapeutic Intervention for REsiDual Sleepiness NCT06698809 | NYU Langone Health | N/A |
| Not Yet Recruiting | Assessment of the Effect of Hypoglossal Nerve Stimulation Therapy on Upper Airway Collapsibility During Drug-i NCT07337239 | University Hospital, Antwerp | N/A |
| Active Not Recruiting | The Effect of Continuous Positive Airway Therapy on the Blood Pressure in Sleepy vs Non-sleepy Patients With O NCT07497412 | King's College London | — |
| Recruiting | Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway P NCT07225686 | Amgen | Phase 3 |
| Recruiting | Disrupted Sleep and Concurrent Ectopy or Atrial Fibrillation NCT07220525 | University of California, San Francisco | N/A |
| Withdrawn | Intraoperative Identification and Stimulation of the Glossopharyngeal Nerve NCT05754216 | Vanderbilt University Medical Center | N/A |
| Recruiting | Evaluation of the Restera™ Serene™ System in Adults With Obstructive Sleep Apnea NCT07303452 | Restera, Inc. | N/A |
| Recruiting | Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airw NCT07226765 | Amgen | Phase 3 |
| Enrolling By Invitation | Automated Manual Lymphatic Drainage Therapy to Improve Glymphatic Function in OSA Patients NCT07301762 | Mayo Clinic | N/A |
| Recruiting | Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Transverse Orthodontic Deficiency in Children NCT07086612 | Fondation Hôpital Saint-Joseph | N/A |
| Recruiting | DISE-HNS Effect Study NCT06372847 | University Hospital, Antwerp | N/A |
| Recruiting | Precision Health and Smart Telerehabilitation in OSA NCT07254026 | National Cheng-Kung University Hospital | N/A |
| Enrolling By Invitation | Impact of Comparing Treatment Status With Other CPAP Users NCT07124975 | Kimihiko Murase | N/A |
| Recruiting | Effectiveness of NOA OATMAD NCT07111962 | University of Alberta | — |
| Not Yet Recruiting | Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindnes NCT06023927 | Northwell Health | — |
| Recruiting | DRonabinol Treatment of OSA NCT06477952 | VA Office of Research and Development | Phase 1 / Phase 2 |
| Recruiting | Severe Label Expansion for EVO Products Trial NCT07090395 | ProSomnus Sleep Technologies | N/A |
| Recruiting | Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through Mandibular Advancement NCT07132307 | Washington University School of Medicine | N/A |
| Not Yet Recruiting | CPAP and Glucose Metabolism in Non-Diabetic OSA Subjects NCT05335083 | Woolcock Institute of Medical Research | N/A |
| Not Yet Recruiting | Superimposition of Intra-oral Scans in MAD Therapy for OSA NCT06612008 | Amsterdam UMC, location VUmc | — |
| Not Yet Recruiting | Precision OSA Therapy Based on Phenotypes and Endotypes NCT06825923 | Nanjing Medical University | — |
| Recruiting | Obstructive Sleep Apnea Non-PAP Outcomes and Viable Alternatives NCT07074288 | Washington University School of Medicine | N/A |
| Not Yet Recruiting | Device-Assisted Oropharyngeal Rehabilitation in Obstructive Sleep Apnea Patients Using Continuous Positive Air NCT06999746 | National Cheng-Kung University Hospital | N/A |
| Recruiting | App-Based Optimization of Long-Term CPAP Adherence and Quality of Life NCT06381115 | Mayo Clinic | N/A |
| Recruiting | EURO-STIM Registry NCT06971796 | Inspire Medical Systems, Inc. | — |
| Not Yet Recruiting | Knowledge, Attitude, and Practice of Pediatric Dentists Toward Obstructive Sleep Apnea Among Children NCT06970873 | Cairo University | — |
| Completed | Alesis OSA-1 Obstructive Sleep Apnea Treatment NCT06949969 | Photonica USA, LLC | N/A |
| Recruiting | Impact of Muscle Training Device on Non-Severe OSA NCT06910930 | Thammasat University Hospital | N/A |
| Recruiting | Addressing Unintentional Leakage When Using Nasal CPAP - Study B NCT06570629 | University of Sao Paulo General Hospital | N/A |
| Recruiting | Addressing Unintentional Leakage When Using Nasal CPAP - Study A NCT06570616 | University of Sao Paulo General Hospital | N/A |
| Recruiting | Changing Lifestyle in OSA Males Who Suffer Metabolic Syndrome and Impotence: Is There a Response? NCT06960746 | Cairo University | N/A |
| Not Yet Recruiting | Development of the Drug and Alcohol Respiratory Health Test NCT06921278 | King's College London | — |
| Recruiting | Evaluation of a Novel Auto-Adjusting Positive Airway Pressure Algorithm for the Treatment of Obstructive Sleep NCT06769607 | ResMed | N/A |
| Recruiting | Optimizing the Management of OSA in Children With Down Syndrome NCT07334444 | University Hospital, Strasbourg, France | — |
| Recruiting | Clinical Outcomes of Continuous Positive Airway Pressure Treatment in People With Obstructive Sleep Apnea and NCT06834724 | Vrije Universiteit Brussel | — |
| Not Yet Recruiting | PAP Systems External Clinical Studies (ECS) NCT06562205 | ResMed | N/A |
| Completed | A Study to Assess the Efficacy and Safety of Lorundrostat in Participants With Obstructive Sleep Apnea and Hyp NCT06785454 | Mineralys Therapeutics Inc. | Phase 2 |
| Not Yet Recruiting | Sleep-Disordered Breathing in the Acute Phase After Stroke and Neuropsychiatric Outcomes NCT06811948 | Blekinge County Council Hospital | — |
| Recruiting | Patients with Coronary Artery Disease or At High Cardiovascular Risk: Measuring Compliance with Treatment for NCT06568159 | University Hospital, Montpellier | — |
| Recruiting | Cognition After OSA Treatment Among Native American People (CATNAP) NCT06227572 | Washington State University | N/A |
| Recruiting | Brain Fog in Sleep Apnea NCT06664450 | Fondazione Don Carlo Gnocchi Onlus | — |
| Withdrawn | Close Obstructive Sleep Apnea (OSA) Trial NCT06113562 | University of Miami | N/A |
| Active Not Recruiting | Post-Operative Steroids After Sleep Surgery NCT06818981 | Medical University of South Carolina | Phase 2 |
| Suspended | Impact of Exogenous Ketones on Sleep Disruption in Vulnerable Populations NCT06655649 | Johns Hopkins University | Phase 1 |
| Recruiting | Combining Light Therapy and CPAP in Depression NCT06781593 | Hôpital le Vinatier | N/A |
| Recruiting | Cardiometabolic Risk Effects of Short-term Cessation of Neurostimulation Therapy NCT06720545 | Columbia University | N/A |
| Not Yet Recruiting | Adaptation and Validation of Pediatric Sleep Questionnaire (PSQ) in Arabic NCT06141707 | Minia University | — |
| Not Yet Recruiting | Long-term CPAP Effect with Obstructive Sleep Apnea: a Telemedicine-based NCT06738940 | National Taiwan University Hospital | N/A |
| Withdrawn | Pressure Relief Algorithm Eval NCT06407999 | SleepRes Inc. | N/A |
| Recruiting | Diaphragmatic Function and Respiratory Drive in OSA and COPD NCT07003399 | Nanjing Medical University | — |
| Not Yet Recruiting | Surgical Treatment for Patients With Obstructive Sleep Apnea by Using Da Vinci SP Surgical System NCT06766760 | Chang Gung Memorial Hospital | N/A |
| Not Yet Recruiting | Tonsillectomy vs. Tonsillotomy in Adults With Obstructive Sleep Apnea NCT06376383 | University of Aarhus | N/A |
| Not Yet Recruiting | An Interactive Mobile Care on Self-management Among T2DM with OSA NCT06760715 | Chang Gung University of Science and Technology | N/A |
| Recruiting | Strengthening Inspiratory and Oropharyngeal Muscles in Moderate Obstructive Sleep Apnea Hypopnea Syndrome NCT06471751 | Centre Hospitalier Universitaire de Saint Etienne | N/A |
| Recruiting | Efficacy of Walking Exercise With Dog on Tinnitus Complaints in Sleep Apnea (Obstructive Sleep Apnea) NCT06803095 | Cairo University | N/A |
| Recruiting | Impact of Severe Obstructive Sleep Apnea-Hypopnea Syndrome on Auditory-Cognitive Processing NCT07039500 | Peking University First Hospital | — |
| Withdrawn | TheraPAP Adherence Crossover Study NCT06413134 | SleepRes Inc. | N/A |
| Recruiting | OurSleepKit To Support CPAP Adherence NCT06621511 | National Heart, Lung, and Blood Institute (NHLBI) | N/A |
| Active Not Recruiting | Systematic Screening for Obstructive Sleep Apnea During Preoperative Consultation Using AI-preoperative Agents NCT06779682 | Intelligence Anesthesia | — |
| Recruiting | Assessment of OSA in Latin American and Response to Neuromod Therapy NCT06762873 | Lunair Medical | EARLY_Phase 1 |
| Recruiting | Smart Pillows for Enhancing Sleep Quality NCT06594627 | Indiana University | N/A |
| Recruiting | Efficacy of Shitali Respiratory Rehabilitation Program in Obstructive Sleep Apnea NCT06715228 | Cairo University | N/A |
| Not Yet Recruiting | Comparison of Methodology Proposed by the SFAR for the Detection by Videoconference of Obstructive Sleep Apnea NCT05711329 | Astes | — |
| Recruiting | A Study of Sex Differences in Neurocirculatory Control NCT06261034 | Mayo Clinic | — |
| Recruiting | Bright Light Therapy for OSA NCT05917119 | VA Office of Research and Development | N/A |
| Enrolling By Invitation | Long-term Evaluation of Nasopharyngeal Airway in Hypotonia NCT06614582 | University of Michigan | N/A |
| Enrolling By Invitation | Mediterranean Diet Versus Standard Diet on Candiormetabolic Indicator in Patients With Apnea NCT06782737 | Coordinación de Investigación en Salud, Mexico | N/A |
| Recruiting | Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Small Tonsils NCT06258837 | Oregon Health and Science University | N/A |
| Completed | Evaluation of Auto-EPAP for Management of Upper Airway Obstruction During Non-Invasive Ventilation NCT06560411 | Breas Medical, Inc. | N/A |
| Recruiting | Safety and Effectiveness of Slow Wave Device for the Treatment of Obstructive Sleep Apnea NCT06519149 | Slow Wave, Inc. | — |
| Not Yet Recruiting | PAP Systems Internal Clinical Studies (ICS) NCT06173050 | ResMed | N/A |
| Not Yet Recruiting | Effect of ALA on Retrolingual Collapse in Patients With Multilevel Obstructive OSA NCT06538701 | Assiut University | N/A |
| Recruiting | Prospective Study Between Polysomnography (PSG) and Novel Ultrasonic Jaw Tracking Device in Patients with Slee NCT06862297 | Taipei Medical University WanFang Hospital | N/A |
| Recruiting | Mini-dose Dexmedetomidine-Esketamine Supplemented Analgesia in Patients at High-risk of OSA NCT06566482 | Peking University First Hospital | Phase 4 |
| Not Yet Recruiting | 12-week Tele-exercise Program in Patients With OSA NCT06467682 | University of Cyprus | N/A |
| Recruiting | Conventional CPAP Airsense 10 VS Portable Air-Mini CPAP For Obstructive Sleep Apnea (CASPAM) NCT06564896 | National University of Malaysia | N/A |
| Active Not Recruiting | Adherence to Health Coaching with Wearable Devices: Enhancing Patient Engagement and Outcomes NCT06525337 | Coastal Carolina University | N/A |
| Recruiting | Unveiling the Neural Mechanisms of 5-HT7 in Sleep Apnea Induced by Arousal Dysregulation NCT06608888 | Beijing Tsinghua Chang Gung Hospital | — |
| Recruiting | Non-inferiority Analysis of Two Titration Methods for Hypoglossal Nerve Stimulation Therapy NCT06559956 | University Hospital, Antwerp | — |
| Recruiting | Clinical Study on the Effect of CPAP on AF Recurrence After Catheter Ablation in Patients with AF and OSA NCT06542263 | Second Affiliated Hospital of Soochow University | — |
| Recruiting | Inspire Singapore Study NCT06540716 | Inspire Medical Systems, Inc. | N/A |
| Recruiting | Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention NCT06390345 | Seattle Institute for Biomedical and Clinical Research | N/A |
| Completed | Identification of Oxygen Desaturation in Patients Admitted Following Adenotonsillectomy' NCT06512285 | Baylor College of Medicine | — |
| Not Yet Recruiting | The Effect of OSA on Severity and Prognosis of Patients With IgAN NCT06393036 | Peking University First Hospital | — |
| Not Yet Recruiting | The Effect of OSA on Pregnancy and Fetal Outcomes NCT06391138 | Peking University First Hospital | — |
| Not Yet Recruiting | The Effect of OSA on Severity and Prognosis of Patients With CKD NCT06393023 | Peking University First Hospital | — |
| Recruiting | Free Walking Exercise in Obstructive Sleep Apnea Patients With Non-alcoholic Fatty Liver NCT06508190 | Ahram Canadian University | N/A |
| Recruiting | North West London Pebble Pathway: Automated OSA Diagnosis NCT06507228 | Patrik Bachtiger | N/A |
| Recruiting | Positional Therapy for Childhood Obstructive Sleep Apnoea NCT06453018 | Chinese University of Hong Kong | N/A |
| Not Yet Recruiting | Effect of OSA Resulting From Chronic Tonsillitis on Pregnancy Outcomes NCT06391151 | Peking University First Hospital | — |
| Not Yet Recruiting | Ambulatory Blood Pressure Control and Cognition in Patients With Obstructive Sleep Apnea (AMPLE) NCT06463002 | National University Hospital, Singapore | — |
| Recruiting | XOR Levels in OSA Patients (XOR-OSA) NCT06554496 | Nanjing Medical University | N/A |
| Recruiting | The Adherence of Proactive Sleep Apnea Therapy NCT06319482 | NovaResp Technologies Inc | N/A |
| Recruiting | TipTraQ Home Sleep Test Validation Study, VGH NCT06474390 | PranaQ Pte. Ltd. | — |
| Completed | Pre- and Postoperative Apnea-Hypopnea Index After Same-Day Discharge Bariatric Surgery NCT06452784 | Rijnstate Hospital | — |
| Recruiting | The Efficacy and Maintain Effect of OPR on OSA Patients After Palatal Surgery NCT06115018 | Yi-Ju, Lai | N/A |
| Recruiting | Whole Food Plant-based Diet Effect on Obstructive Sleep Apnea NCT06395181 | Mayo Clinic | N/A |
| Active Not Recruiting | Obstructive Sleep Apnea (OSA) and Sex-Specific Responses to N-acetylcysteine (NAC) NCT06311045 | NYU Langone Health | N/A |
| Active Not Recruiting | RePOSA-Revealing the Efficacy of IHL-42X Use in Patients With OSA NCT06146101 | Incannex Healthcare Ltd | Phase 2 / Phase 3 |
| Not Yet Recruiting | Lifestyle Intervention for Obstructive Sleep Apnea in Women NCT06370806 | Universidad de Granada | N/A |
| Unknown | Minimally Invasive Electrical Stimulation Of The Nerve Hypoglossal for the Treatment of Obstructive Sleep Apne NCT05914948 | Capri Medical Limited | N/A |
| Recruiting | The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study NCT05988385 | California Pacific Medical Center Research Institute | N/A |
| Recruiting | Hypoglossal Nerve Stimulation Therapy in Patients With Obstructive Sleep Apnea: Belgian Registry NCT06332404 | University Hospital, Antwerp | — |
| Recruiting | Lifestyle and Physical Activity as Part Of Obstructive Sleep Apnea Treatment NCT06382883 | Filha ry | N/A |
| Recruiting | Impact of Sleep-Disordered Breathing Management in Systemic Hypertension Control: METASLEEP Project NCT05986487 | Sociedad Española de Neumología y Cirugía Torácica | — |
| Completed | Comparison of Apnea-Hypopnea Index in Patients With or Without Preventive Oxygen Therapy After Bariatric Surge NCT06432933 | Rijnstate Hospital | N/A |
| Recruiting | Metabolic Endpoints for Obstructive Sleep Apnea Following Twelfth Cranial Nerve Stimulation NCT06317701 | University of Chicago | — |
| Recruiting | MicroRNAs as Biomarkers for Obstructive Sleep Apnea NCT06189755 | University of Pennsylvania | — |
| Unknown | Whitsundays (Nasal) Singapore External Clinical Study 1 Protocol NCT05255744 | ResMed | N/A |
| Unknown | The Comfort of Proactive Sleep Apnea Therapy NCT06144892 | NovaResp Technologies Inc | N/A |
| Unknown | High Flow Nasal Cannula and Conventional Oxygen Therapy in the Postoperative Management of Patients With Mild NCT06306651 | Ain Shams University | N/A |
| Recruiting | Clinical Association Between Obstructive Sleep Apnea, Facial Pigmentation, and Vasovagal Symptoms. NCT06331819 | Jordan Collaborating Cardiology Group | — |
| Completed | TPAP for Comfort in OSA NCT06264128 | SleepRes Inc. | N/A |
| Completed | TheraPAP Equivalence Crossover Study NCT06238362 | SleepRes Inc. | N/A |
| Unknown | Efficacy of Stellate Ganglion Block in Obstructive Sleep Apnea NCT06265792 | Zeng Changhao | N/A |
| Unknown | Effectiveness of Stellate Ganglion Block for the Treatment of Obstructive Sleep Apnea NCT06319612 | Copka Sonpashan | N/A |
| Recruiting | Validation of Pediatric Sleep Questionnaire on a Swedish Cohort NCT06367400 | Uppsala University | — |
| Recruiting | Multidimensional Evaluation of Patients' Affected by Obstructive Apnea Syndrome (OSAS) Before and After Ventil NCT06312956 | Istituto Auxologico Italiano | — |
| Unknown | Stellate Ganglion Block in Obstructive Sleep Apnea NCT06249490 | Zeng Changhao | N/A |
| Completed | TipTraQ Home Sleep Test Validation Study, Duke NCT06351878 | PranaQ Pte. Ltd. | — |
| Recruiting | Obstructive Sleep Apnea Treatment From Acute to Chronic Phase of Stroke NCT07044830 | Hospital das Clínicas de Ribeirão Preto | N/A |
| Recruiting | Structured Testing and Treatment for Obstructive Sleep Apnea in Patients With Atrial Fibrillation NCT06263608 | University Hospital, Antwerp | N/A |
| Recruiting | The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome) NCT05237505 | University of California, San Diego | Phase 2 |
| Completed | Lifestyle Program for Obstructive Sleep Apnea With Severe Obesity NCT05343000 | Mayo Clinic | N/A |
| Recruiting | Registry Study on Prescription, Patient Pathways, Therapy Efficacy and Usage of Mandibular Advancement Devices NCT03924817 | ResMed | — |
| Unknown | Is My Sleep Tracker Tracking my Sleep? NCT06174558 | Respiratory Specialists | — |
| Unknown | Skiin-PSG Sleep Apnea NCT06247878 | Myant Medical Corp. | — |
| Terminated | Obstructive Sleep Apnea - Autonomic and Vascular Exploration NCT05920083 | Raphael Heinzer | N/A |
| Recruiting | Endotypic Traits and Obstructive Sleep Apnea Surgery NCT05953610 | University of California, Los Angeles | Phase 2 |
| Recruiting | Phototherapy for Non-responders to Oral Appliance Therapy for Obstructive Sleep Apnea NCT06960200 | University of Alberta | Phase 2 |
| Recruiting | Exploring the Use of Phototherapy to Improve CPAP Compliance NCT06960161 | University of Alberta | Phase 1 |
| Recruiting | Time Restricted Eating in Sleep Apnea NCT06047496 | University of California, San Diego | EARLY_Phase 1 |
| Recruiting | Trazodone on OSA Endotypes NCT06286189 | Brigham and Women's Hospital | Phase 1 / Phase 2 |
| Completed | CPAP and Physiotherapy for Heart Failure and Sleep Apnea in the Elderly NCT07061171 | Weihua Peng | N/A |
| Recruiting | Effect of CPAP Treatment in Patients With Severe Uncontrolled Asthma: The ASTHMA-SLEEP Trial NCT06314477 | Hospital Clinic of Barcelona | N/A |
| Completed | MOdification of Fluid Distribution in 90 Minutes NCT05786248 | Poitiers University Hospital | N/A |
| Completed | Mandibular Advancement Device and Changes in Nocturia NCT05562388 | Fernanda Yanez Regonesi | N/A |
| Withdrawn | Side Effects of the Mandibular Advancement Device for Apnea Treatment on Dental Occlusion and Masticatory Func NCT05420129 | University of Barcelona | — |
| Completed | Evaluation of the F&P Caramel Nasal Mask, US, 2023 NCT06060717 | Fisher and Paykel Healthcare | N/A |
| Recruiting | Screening Using Portable Electronic Recorders for Sleep Apnea in Hypertensive At-Risk Populations (SUPER-SHARP NCT05918120 | Sunnybrook Health Sciences Centre | N/A |
| Recruiting | Mechanisms for Atrial Fibrillation in Obstructive Sleep Apnea NCT06465134 | Danderyd Hospital | — |
| Recruiting | Down Syndrome Obstructive Sleep Apnea NCT06043440 | Brigham and Women's Hospital | Phase 2 |
| Completed | Chronic Care Management With Wearable Devices in Patients Prescribed Positive Airway Pressure Therapy (mPAP) T NCT06039865 | VA Greater Los Angeles Healthcare System | N/A |
| Completed | Managing Opioid Related Sleep Apnea With Acetazolamide NCT06043830 | University of California, San Diego | Phase 2 |
| Recruiting | Enhancing PAP Adherence Among Spanish-speaking Hispanic Adults With OSA NCT05618444 | Geisinger Clinic | N/A |
| Withdrawn | Screening for Obstructive Sleep Apnea in Medical Patients NCT05980936 | Jordan Collaborating Cardiology Group | — |
| Unknown | Zolpidem on CPAP Acclimatization in OSA NCT06084130 | Siriraj Hospital | Phase 4 |
| Unknown | Postoperative Pulmonary Complications In Obstructive Sleep Apnea Patients NCT06041750 | Cukurova University | — |
| Completed | Oran Park Mask External Clinical Study (3) Marketing Claims Study NCT06079866 | ResMed | N/A |
| Completed | Stroke and CPAP Outcome Study 3 NCT06029959 | University of Washington | N/A |
| Active Not Recruiting | Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome NCT05933603 | University of Arizona | Phase 2 |
| Recruiting | Community Health Advocates for Motivating PAP Use in Our Neighborhoods. NCT06047353 | University of Miami | N/A |
| Recruiting | Sleep Apnea, Neurocognitive Decline and Brain Imaging in Patients With Subjective or Mild Cognitive Impairment NCT06150352 | The University of Hong Kong | — |
| Completed | Bioavailability, Bioequivalence and Tolerability of IHL-42X Compared to the Reference Drugs NCT05857384 | Incannex Healthcare Ltd | Phase 1 |
| Completed | Novel Myofunctional Water Bottle to Reduce OSA and Snoring Study NCT05371509 | Mayo Clinic | N/A |
| Recruiting | Effectiveness of an E-health Intervention in Patients With Obstructive Sleep Apnoea NCT05380726 | Universitat de Lleida | N/A |
| Unknown | Assessment of Obstructive Sleep Apnea Syndrome in Non-Obese Patients NCT05814796 | Assiut University | — |
| Completed | Endotype-Targeted Therapy to Rescue OSA Patients Struggling With CPAP Adherence (TOP-CPAP) NCT05951023 | University of California, San Diego | Phase 2 |
| Unknown | Effect of Eszopiclone on Adherence to CPAP and Severity of Insomnia in Patients With COMISA NCT06017921 | University of Sao Paulo General Hospital | Phase 4 |
| Completed | Study of the Resvent RXiBreeze™ PAP System to Treat Obstructive Sleep Apnea NCT06008678 | Resvent Holding USA LTD | N/A |
| Recruiting | Clinical Characteristics and Molecular Mechanism of Patients With Obstructive Sleep Apnea NCT07277608 | Capital Medical University | — |
| Recruiting | Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS) NCT05508971 | Oregon Health and Science University | N/A |
| Enrolling By Invitation | The Effect of OSA on Brain Waste Clearance NCT05606991 | Woolcock Institute of Medical Research | N/A |
| Unknown | Feasibility and Effectiveness of a Ring-type Blood Pressure Measurement Device NCT06084065 | Seoul National University Hospital | N/A |
| Active Not Recruiting | A Study of Retatrutide (LY3437943) in Participants With Type 2 Diabetes Mellitus Who Have Obesity or Overweigh NCT05929079 | Eli Lilly and Company | Phase 3 |
| Active Not Recruiting | A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight NCT05929066 | Eli Lilly and Company | Phase 3 |
| Recruiting | Microbiome and Metabolomics Profiling in Children With OSA NCT06452992 | Chinese University of Hong Kong | — |
| Recruiting | Rescue Pharmacotherapy for OSA NCT05293600 | Brigham and Women's Hospital | Phase 1 / Phase 2 |
| Completed | Developement of TipTraQ Home Sleep Test NCT06474351 | PranaQ Pte. Ltd. | — |
| Unknown | Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized COPD Patients NCT03647462 | Kaiser Permanente | N/A |
| Completed | Whitsundays (Nasal) Mask Take Home Study (90 Days) NCT06036329 | ResMed | N/A |
| Recruiting | Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adeni NCT05656365 | National Institute of Allergy and Infectious Diseases (NIAID) | — |
| Recruiting | Patient-centered and Neurocognitive Outcomes with Acetazolamide for Sleep Apnea NCT05804084 | University of California, San Diego | Phase 2 |
| Completed | The IPAd Study: Exploring the Association Between Insomnia and Positive Airway Pressure Adherence in Children NCT05949164 | The Hospital for Sick Children | — |
| Completed | Tongue Morphology and Posterior Airway Space as Predictors of Response in Patientswith Hypoglossal Nerve Stimu NCT06154577 | Cantonal Hosptal, Baselland | — |
| Withdrawn | Magnetic Resonance Imaging in Obstructive Sleep Apnea NCT02207127 | University of Southern California | — |
| Recruiting | OROPHARYNGEAL MYOFUNCTIONAL THERAPY IN OBSTRUCTIVE SLEEP APNEA NCT06681974 | Instituto de Investigación Marqués de Valdecilla | Phase 3 |
| Withdrawn | Improving 24-hour Blood Pressure in Obstructive Sleep Apnea NCT04021550 | University of British Columbia | EARLY_Phase 1 |
| Completed | AD816 Crossover Study NCT05793684 | Apnimed | Phase 2 |
| Completed | Sleep Apnea Study in Adults Using DreamPort-Eclipse and a Traditional Nasal Mask NCT05818540 | Bleep, LLC | N/A |
| Completed | Dextrose Prolotherapy Versus LLLT in Treatment of Obstructive Sleep Apnea NCT06427161 | Mansoura University | N/A |
| Active Not Recruiting | Impact of Tele-visit on Patients Continous Positive Airway Pressure (CPAP) Follow-up by Home Care Provider NCT05653804 | AGIR à Dom | N/A |
| Completed | Comparison of Demographic Data Mentioned by the Patients or Measured by a Physician NCT05709964 | Astes | — |
| Recruiting | Oropharyngeal Exercises to Treat Obstructive Sleep Apnea NCT05678088 | Sunnybrook Health Sciences Centre | N/A |
| Completed | The Association Between Obstructive Sleep Apnea Severity and Red Blood Cells Indices NCT06265129 | Mansoura University | — |
| Recruiting | Sleep Apnea and Cognitive Function in Subjects With Subjective or Mild Cognitive Impairment NCT06089096 | The University of Hong Kong | — |
| Completed | TipTraQ Home Sleep Test Study, SHH NCT06633887 | PranaQ Pte. Ltd. | — |
| Recruiting | Intraoperative Ansa Cervicalis Nerve (ACN) Stimulation NCT05650710 | Vanderbilt University Medical Center | N/A |
| Unknown | Analysis of Mandibular Movements in Ventilated Children With Sleep Apnea Syndrome NCT05908188 | University Hospital, Grenoble | — |
| Recruiting | Effect of CPAP on Blood Pressure in Excessively Sleepy Obstructive Sleep Apnea Subtype NCT05742360 | Ohio State University | — |
| Completed | Screening Moderate to Severe Obstructive Sleep Apnea With Wearable Device NCT06454318 | Thammasat University Hospital | — |
| Completed | Acetazolamide on REM OSA NCT05589792 | Brigham and Women's Hospital | Phase 1 / Phase 2 |
| Active Not Recruiting | Multi-morbidity Screening in People With Type 2 Diabetes and Pre Diabetes NCT06053177 | University of Liverpool | — |
| Recruiting | Predictors of Post-COVID-19 Clinical and Cognitive Consequences NCT06291870 | VA Office of Research and Development | — |
| Recruiting | Diurnal Evaluation of OSA Upper Airway Collapsibility and Muscle Responsiveness NCT06334601 | Istituto Auxologico Italiano | — |
| Recruiting | OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit NCT05156112 | VA Office of Research and Development | N/A |
| Unknown | Oximetry in Children for Sleep Apnea Diagnosis NCT05634096 | Central Hospital, Nancy, France | — |
| Recruiting | Prospective National Multi-center Registry of Obstructive Sleep Apnea Syndrome in Hypertensive Patients in Chi NCT05735444 | Shanghai Jiao Tong University School of Medicine | — |
| Completed | Predictability of OSA With a Subjective Screening Scale (OSASSS1) NCT06092710 | Center for Sleep Medicine - Clinique André Renard | — |
| Enrolling By Invitation | Prolonged Extubation in Gastric Cancer With OSA NCT07362706 | Qilu Hospital of Shandong University | — |
| Recruiting | Intermittent Hypoxia-initiated Plasticity in Humans: A Multi-pronged Therapeutic Approach to Treat Sleep Apnea NCT05558501 | VA Office of Research and Development | Phase 1 / Phase 2 |
| Recruiting | Mucosal Inflammation in Children With OSA NCT06452979 | Chinese University of Hong Kong | — |
| Terminated | Assessment of Continuous Positive Airway Pressure Therapy in OSA and ILD NCT03901534 | Columbia University | N/A |
| Active Not Recruiting | Restoring Metabolic and Reproductive Health With Sleep in PCOS Study, CPAP Trial NCT05920694 | University of California, San Francisco | N/A |
| Unknown | Screening for Obstructive Sleep Apnea Syndrome in Children NCT05896176 | Université Libre de Bruxelles | — |
| Completed | Acetazolamide for Obstructive Sleep Apnea to Improve Heart Health NCT05616260 | University of California, San Diego | Phase 2 |
| Completed | Validation of a Ring-type Wearable Device NCT05746338 | Shanghai Jiao Tong University School of Medicine | N/A |
| Recruiting | Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome NCT06030349 | Children's Health Ireland | — |
| Recruiting | Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia NCT05527652 | University of Michigan | N/A |
| Completed | Evaluation of the F&P Toffee Nasal Pillows Mask, US, 2022 NCT05573763 | Fisher and Paykel Healthcare | N/A |
| Completed | Field Usability Study of Eclipse Mask NCT05559047 | Bleep, LLC | — |
| Recruiting | Ansa Cervicalis and Hypoglossal Nerve Stimulation in OSA NCT05501236 | Vanderbilt University Medical Center | N/A |
| Active Not Recruiting | Dexamethasone Treatment for OSA in Children NCT05638087 | The Hospital for Sick Children | Phase 3 |
| Completed | Simulated In-House Usability Study of Eclipse Continuous Positive Airway Pressure (CPAP) Device NCT05570747 | Bleep, LLC | — |
| Recruiting | Updating Deep Learning Algorithms for OSA Monitoring NCT06522815 | Sky Labs | N/A |
| Recruiting | Photobiomodulation for Pediatric Hypertrophic Tonsils NCT05459935 | University of Alberta | N/A |
| Recruiting | Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea NCT05303987 | Erin Kirkham | Phase 2 |
| Recruiting | Sleep Quality Evolution: Dreem Under CPAP NCT05197855 | University Hospital, Grenoble | N/A |
| Completed | Design and Usability Testing of a Tailored Intervention About Sleep and Sleep Disorders Among Transportation W NCT05039528 | Brigham and Women's Hospital | N/A |
| Unknown | Sociological Determinants of Positive Airway Pressure Adherence in OSA Patients NCT05385302 | University Hospital, Grenoble | — |
| Completed | Personal Therapy Comfort Settings Pilot Clinical Study NCT05376137 | ResMed | N/A |
| Completed | Early Feasibility Study of Transcutaneous Upper Airway Stimulation in Obstructive Sleep Apnea NCT05881512 | Somnial Inc | N/A |
| Completed | Evaluation of the Toffee Nasal and Toffee Nasal Pillows Mask in Home, USA, 2022 NCT05496062 | Fisher and Paykel Healthcare | N/A |
| Terminated | Severe OSA Study (SOS) NCT05445869 | ProSomnus Sleep Technologies | N/A |
| Completed | Effect on Sleep of Surgical Treatment of Severe Nasal Obstruction NCT05582070 | University Hospital, Bordeaux | N/A |
| Completed | Effect Of Tele-Yoga On Aerobic Capacity, Respiratory Muscle Strength, And Cognitive Performance In Patients Wi NCT05517252 | Uskudar University | N/A |
| Unknown | Long-term Effect of High Flow Nasal Canula Therapy on Obstructive Sleep Apnea NCT05549310 | Qilu Hospital of Shandong University | N/A |
| Unknown | Clinical Efficacy of High-flow Nasal Cannula Oxygen Therapy in Patients With Obstructive Sleep Apnea NCT05549245 | Qilu Hospital of Shandong University | N/A |
| Terminated | StimAire Sleep Study NCT05374941 | StimAire Australia Pty Ltd | N/A |
| Completed | Effect of Different Exercise Modalities Training in Patients With Obstructive Sleep Apnea. NCT06087900 | Chulalongkorn University | N/A |
| Completed | Efficacy of Clinical Decision Support and Sleep Navigation (Sleep PASS) NCT05353998 | Children's Hospital of Philadelphia | N/A |
| Terminated | Health Outcomes With CPAP or NIV in Patients With COPD and a Sleep Related Breathing Disorder NCT05623709 | University of Alberta | — |
| Recruiting | Phenotypic and Genotypic Characterization of Patients With Dysmetabolism in Greenland NCT06264427 | Steno Diabetes Center Greenland | N/A |
| Completed | Long-term Effects of Lipoabdominoplasty on Pulmonary Function and Sleep Apnea Risk in Obese Subjects NCT07029750 | Atlas University | — |
| Completed | Effects of Different Treatment Modalities for Obstructive Sleep Apnea on Temporomandibular Joint NCT05510882 | Mansoura University | N/A |
| Unknown | Big Data Analysis of OSA Patients on Positive Airway Pressure (PAP) Treatment: Real-life Monitoring NCT05495347 | Instituto de Investigación Marqués de Valdecilla | — |
| Recruiting | Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy NCT05350332 | Emory University | N/A |
| Active Not Recruiting | Evaluation of an Early Management Strategy for Obstructive Sleep Apnea NCT04613414 | University of Calgary | N/A |
| Completed | Obstructive Sleep Apnea Master Protocol GPIF: A Study of Tirzepatide (LY3298176) in Participants With Obstruct NCT05412004 | Eli Lilly and Company | Phase 3 |
| Completed | Vitamin D and SGLT-2 Inhibitor in CPAP-naive Obstructive Sleep Apnea NCT06690723 | University Malaysia Sarawak | Phase 3 |
| Recruiting | Atomoxetine and DAW2022 on OSA Severity NCT05350215 | Brigham and Women's Hospital | Phase 1 / Phase 2 |
| Completed | Overnight Upper Airway Infiltration in Spinal Cord Injury NCT05391308 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | Effect of EMST Systemic Inflammation and Oxidative Stress in Patients With Moderate OSAS NCT05242406 | Ahi Evren Chest and Cardiovascular Surgery Education and Research Hospital | N/A |
| Unknown | A Smart Sleep Apnea Self-management Support Programme(4S) for Subjects With Sleep Apnea NCT05390138 | The University of Hong Kong | N/A |
| Recruiting | Post Market Clinical Follow Up of ResMed Mask Systems NCT05262439 | ResMed | N/A |
| Recruiting | Metabolism and Sleep Apnea Treatment NCT05539716 | University of Miami | N/A |
| Active Not Recruiting | Evaluation of Trazodone in OSA-MCI NCT05209035 | Chinese University of Hong Kong | Phase 4 |
| Unknown | Identifying Sleep Apnea Patients That Best Respond to Atomoxetine Plus Oxybutynin Therapy NCT05550246 | Brigham and Women's Hospital | Phase 1 / Phase 2 |
| Unknown | Patient Experience and Technical Success of Community Sleep Studies NCT05432102 | Papworth Hospital NHS Foundation Trust | — |
| Recruiting | A Multicenter Retrospective Analysis of Postoperative Respiratory Complications in Children With Obstructive S NCT07305168 | University Hospital, Antwerp | — |
| Completed | Study of Postoperative Respiratory Complications in Children With Obstructive Sleep Apnea (PORC) NCT05308108 | University Hospital, Antwerp | — |
| Unknown | The Role of the Device Operating Under the Continuous Positive Airway Pressure in the Recovery Process of Coch NCT05362890 | Mirjana Grebenar Cerkez | N/A |
| Recruiting | Changes in Body Fat and Morphologic Characteristics Associated With OSA Resolution After Bariatric Surgery NCT05315752 | Centre Hospitalier Universitaire Saint Pierre | — |
| Completed | The Effect of Fibromyalgia Syndrome Accompanying Obstructive Sleep Apnea Syndrome on Clinical Findings NCT05367167 | Kirsehir Ahi Evran Universitesi | — |
| Completed | Pediatric Pain Optimization After Tonsillectomy NCT05244226 | Duke University | Phase 2 |
| Unknown | New Perspective on Exploring the Post-apneic BP Surge in Patients With OSA NCT06172998 | Xu J | EARLY_Phase 1 |
| Completed | Nocebo Effect in OSA Patients With CPAP Treatment NCT05284045 | Hospital Clinic of Barcelona | N/A |
| Completed | Study Watch Sleep Metric Performance Characterization Study NCT05276362 | Verily Life Sciences LLC | — |
| Completed | Counterfactual Thinking and Decision-making in OSA Syndrome NCT05768633 | Istituto Auxologico Italiano | — |
| Withdrawn | Spironolactone to Improve Apnea and Cardiovascular Markers in Obstructive Sleep Apnea Patients NCT04205136 | University of Michigan | Phase 4 |
| Terminated | Effective Conversion of Individuals at Risk NCT05112757 | Philips Electronics Nederland B.V. acting through Philips CTO organization | N/A |
| Completed | Applying Best Clinical Practices to Patients at High Risk of Respiratory Complications NCT04263363 | University of California, Los Angeles | Phase 4 |
| Completed | Ketorolac on Postoperative Pain Reduction in Pediatric Patients with Adenotonsillectomy NCT05074056 | St. Louis University | Phase 4 |
| Unknown | Vitamin D Levels and Heart Rate Variability on Endothelial Function Via RAAS Augmentation in OSA NCT05232201 | University Malaysia Sarawak | — |
| Recruiting | Pathophysiological Endotyping Using Baseline Polysomnography Data NCT05267808 | University Hospital, Antwerp | — |
| Completed | Comparison of the Effect of Supine and Prone Position on the Ultrasonographic Airway Measurements NCT05197400 | Ankara City Hospital Bilkent | N/A |
| Unknown | Comparing the Side-lying Sleep Positioning to Back-lying in Infants With Cleft Palate NCT04478201 | Manchester University NHS Foundation Trust | N/A |
| Completed | Long-term Results of Tonsillectomy in the Treatment of Obstructive Sleep Apnea in Adults NCT05049369 | Turku University Hospital | N/A |
| Completed | Abdominal Breathing for Depression, Anxiety, Heart Rate Variability in Obstructive Sleep Apnea Patients NCT05594212 | National Taipei University of Nursing and Health Sciences | N/A |
| Completed | Effects of Mandibular Advancing Device in Obstructive Sleep Apnea NCT07003854 | Ain Shams University | N/A |
| Completed | Tonsillectomy and Expansion Sphincter Pharyngoplasty Operations NCT06119841 | Saglik Bilimleri Universitesi | N/A |
| Completed | Precision Sleep Medicine NCT06903481 | University Hospital, Basel, Switzerland | — |
| Unknown | Effects of Newly-created Individualized Upper Airway Muscle Functional Training on Patients With OSA NCT05346705 | First Hospital of China Medical University | N/A |
| Completed | BASET Scoring: A Novel Simple Biometric Score and Potential Tool for Diagnosis and Grading of Obstructive Slee NCT05511974 | Mansoura University | N/A |
| Unknown | Obstructive Sleep Apnea Treatment With CPAP With and Without the Use of Expiratory Pressure Relief Technology NCT05219591 | University of Sao Paulo General Hospital | N/A |
| Unknown | Novel Inhibitors of Lipolysis in the Treatment of Lipid a Glucose Metabolism in Obstructive Sleep Apnea Syndro NCT05245240 | Faculty Hospital Kralovske Vinohrady | N/A |
| Unknown | The Effect of High Intensity Interval Exercise and Myofunctional Therapy on Obstructive Sleep Apnea NCT05311280 | Taoyuan General Hospital | N/A |
| Active Not Recruiting | Novel physIologiC prEdictors of Positive Airway Pressure Effectiveness NCT05067088 | Yale University | — |
| Completed | PAP Adherence After Diet/Lifestyle Intervention in OSA Patients NCT05881824 | University of Crete | N/A |
| Completed | Recording of Multiple Nights Using a New Contactless Device (Sleepiz One Connect) in Obstructive Sleep Apnea NCT05134402 | Samuel Tschopp | — |
| Completed | Effects of Inspiratory Muscle Training on the Severity of Obstructive Sleep Apnea in Individuals After Stroke NCT05135494 | Sarah Network of Rehabilitation Hospitals | N/A |
| Recruiting | Pediatric Post-Approval Registry NCT04457154 | Inspire Medical Systems, Inc. | — |
| Completed | Efficacy, Safety and Tolerability of Sulthiame in Patients With Obstructive Sleep Apnea (OSA) NCT05236842 | Desitin Arzneimittel GmbH | Phase 2 |