Clinical Trials Directory

Trials / Recruiting

RecruitingNCT06030349

Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome

Real World Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea Syndrome in Children With Down Syndrome

Status
Recruiting
Phase
Study type
Observational
Enrollment
200 (estimated)
Sponsor
Children's Health Ireland · Other Government
Sex
All
Age
6 Months – 16 Years
Healthy volunteers
Not accepted

Summary

The goal of this observational study is to learn about the use of non-invasive ventilation for treatment of obstructive sleep apnoea syndrome in children with Down Syndrome. The main questions it aims to answer are: * What is the impact of non-invasive ventilation on sleep behaviours and quality of life? * What barriers are faced by children and their families in establishing tolerance to non-invasive ventilation? Participants will be asked to complete questionnaires before and after starting treatment. Researchers will compare this data with the results of sleep studies and non-invasive ventilator downloads recorded as part of standard medical care. A sub-group of up to 20 participants will be invited to take part in 45-60 minute interviews exploring expectations, experiences and barriers encountered during non-invasive ventilation therapy.

Detailed description

Our aim is to examine the impact of non-invasive ventilation for treatment of obstructive sleep apnoea syndrome in children with Down Syndrome on behavioural and quality of life outcomes and to establish the specific barriers experienced in establishing adherence to treatment. Information from clinical assessment, sleep studies and device downloads recorded as part of standard care will be combined with questionnaire data to assess for changes in behaviour and quality of life. All participants will undergo questionnaire assessment of barriers experienced. A sub-group of up to 20 participants will be invited to take part in 45-60 minute semi-structured interviews exploring expectations, experiences and barriers encountered.

Conditions

Interventions

TypeNameDescription
DEVICENon-invasive ventilationNon-invasive ventilation

Timeline

Start date
2022-11-28
Primary completion
2027-11-28
Completion
2027-12-28
First posted
2023-09-11
Last updated
2024-02-12

Locations

6 sites across 2 countries: Ireland, United Kingdom

Source: ClinicalTrials.gov record NCT06030349. Inclusion in this directory is not an endorsement.