| Not Yet Recruiting | Autologous Serum Tears With Hyaluronate vs Balanced Salt Solution for Moderate-to-Severe Dry Eye NCT07413172 | University of Miami | Phase 2 |
| Recruiting | Advancing Pediatric Retinal Imaging With Auto-aligned OCT NCT06841575 | Duke University | N/A |
| Recruiting | RESTORE: Comparing Two Approaches to Repeat TT Surgery Performed by Integrated Eye Care Workers (IECWs) NCT07322302 | University of North Carolina, Chapel Hill | N/A |
| Not Yet Recruiting | Switching From Xiidra to TRYPTYR NCT07267481 | Southern College of Optometry | Phase 4 |
| Recruiting | Michigan Screening and Intervention for Glaucoma and Eye Health Through Telemedicine (SIGHT) 2 NCT06934577 | University of Michigan | N/A |
| Recruiting | SGLT2 Inhibitors in Geographic Atrophy NCT07174687 | Washington University School of Medicine | Phase 2 |
| Not Yet Recruiting | Switching From Restasis to TRYPTYR NCT07267299 | Southern College of Optometry | Phase 4 |
| Recruiting | Natural History Study of Patients With EYS-Associated RP NCT07228793 | Sensor Technology for Deafblind | — |
| Recruiting | Impact of TRYPTYR on a Patient's Quality of Life and Ability to Perform Work NCT07266948 | Southern College of Optometry | Phase 4 |
| Recruiting | Widefield Confocal Scanning Laser Ophthalmoscope Optimized for Pediatric and Neonatal Imaging NCT06177639 | Duke University | — |
| Recruiting | Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION) NCT06891443 | Laboratoires Thea | Phase 3 |
| Recruiting | Patterns of Eye Diseases Among Patients Attending The Eye Investigation Unit of Sohag University Hospital NCT06812845 | Sohag University | — |
| Recruiting | Development of a Deep Learning System for Identification of Neuro-Ophthalmological Conditions on Color Fundus NCT06643338 | Fondation Ophtalmologique Adolphe de Rothschild | — |
| Completed | Ophthalmic Diseases and AI: an RCT Study NCT07154680 | North Sichuan Medical College | — |
| Recruiting | Effects of Topical Insulin on Corneal Epithelium Healing After Corneal Crosslinking in Patients With Keratocon NCT06601101 | University of Campinas, Brazil | Phase 3 |
| Recruiting | Holistic Mixed Approaches to Capture the Real Life of Children With Rare Eye Diseases NCT06070467 | University Hospital, Strasbourg, France | — |
| Completed | MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby) NCT06455826 | PYC Therapeutics | Phase 1 |
| Recruiting | Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Deg NCT06394232 | Eyestem Research Pvt. Ltd. | Phase 1 / Phase 2 |
| Active Not Recruiting | Safety and Efficacy Study of IVB102 Injection in Subjects With X-linked Retinoschisis NCT06289452 | InnoVec Biotherapeutics Inc. | EARLY_Phase 1 |
| Completed | A Study to Evaluate the Efficacy and Safety of LASN01 in Patients With Thyroid Eye Disease NCT06226545 | Lassen Therapeutics Inc. | Phase 2 |
| Completed | Collection of Ocular Surface Impressions Cytology of the Living Eye From Patients With Dry Eyes or Limbal Stem NCT06255301 | Centre Hospitalier Universitaire de Saint Etienne | — |
| Active Not Recruiting | Non-Interventional Long Term Follow-up Study of Participants Previously Enrolled in the RESTORE Study NCT06162585 | Nanoscope Therapeutics Inc. | — |
| Recruiting | Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TE NCT06112340 | Sling Therapeutics, Inc. | Phase 2 / Phase 3 |
| Recruiting | Novel Antisense Oligonucleotide Eye Drops for Treating Antibiotic-Resistant Bacterial Keratitis NCT06451172 | Eye & ENT Hospital of Fudan University | EARLY_Phase 1 |
| Completed | Swept Source OCT Imaging With the DREAM VG-OCT NCT05876689 | Robert T. Chang, MD | — |
| Completed | Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Presbyopia NCT06045299 | Corxel Pharmaceuticals | Phase 3 |
| Recruiting | Assessment of the Ocular Microbiome in Health and Disease NCT05414994 | Vanderbilt University Medical Center | — |
| Completed | Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DM NCT06011798 | Unity Biotechnology, Inc. | Phase 2 |
| Completed | Effect of Nutritional Supplement Alpha-ketoglutarate for Age-related Ocular Disease NCT07269704 | Stanford University | EARLY_Phase 1 |
| Unknown | Effect of Peripapillary Atrophy to Diagnose Glaucoma in High Myopia NCT05964634 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Completed | Multimodal Machine Learning for Auxiliary Diagnosis of Eye Diseases NCT05930444 | Eye & ENT Hospital of Fudan University | — |
| Completed | Plasma Pharmacokinetics and Safety of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Subjects With Pr NCT05936489 | LENZ Therapeutics, Inc | Phase 1 |
| Recruiting | Precision Diagnosis and Therapy for Rare Diseases by Interpreting Non-coding Genomes NCT06775561 | IRCCS Azienda Ospedaliero-Universitaria di Bologna | — |
| Completed | OTX-DED for the Short-term Treatment of the Symptoms of Dry Eye Disease (DED) NCT05814757 | Ocular Therapeutix, Inc. | Phase 2 |
| Completed | Fundus Findings and Thiol-Disulfide Homeostais NCT05958927 | Suzan Dogruya | — |
| Terminated | Comfortable and Stabilizing Chin & Forehead Rest Attachment for Slit Lamp Configurations NCT05686421 | NYU Langone Health | N/A |
| Completed | iSCREEN-study: Online Nurse-assisted Eye-screening in Home Healthcare NCT06058637 | Amsterdam UMC, location VUmc | N/A |
| Completed | Phase 3 Efficacy Study of LNZ100 & LNZ101 for the Treatment of Presbyopia NCT05728944 | LENZ Therapeutics, Inc | Phase 3 |
| Completed | Effect of Repeated Low-Level Red-Light Therapy on Retinal Function and Structure NCT05597397 | Shanghai Eye Disease Prevention and Treatment Center | N/A |
| Unknown | Repeated Low-Level Red-Light Therapy Shortens Axial Length NCT05768152 | The Second People's Hospital of Foshan | N/A |
| Completed | Detecting Eye Diseases Via Hybrid Deep Learning Algorithms From Fundus Images NCT06213896 | Ural Telekomunikasyon Sanayi Ticaret Anonim Sirketi | — |
| Unknown | Light Emitting Diodes With a Continuous Spectrum of 430-780nm for Myopia Prevention NCT05728762 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Completed | Phase 3 Safety Study for the Treatment of Presbyopia Subjects NCT05753189 | LENZ Therapeutics, Inc | Phase 3 |
| Recruiting | The Aging Eye Cohort Study NCT05851287 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Active Not Recruiting | Investigating Geographic Atrophy Insights (i-GAIN) Natural History Study NCT05797896 | Complement Therapeutics | — |
| Completed | Imaging of Corneal and Crystalline by Near Infrared Retro-illumination NCT05717543 | Centre Hospitalier Universitaire de Saint Etienne | N/A |
| Unknown | Impact of COVID-19 on Quality of Life of Seniors With Eye Disease and Implementations to Improve Wellness NCT04910282 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | — |
| Completed | Phase 3 Evaluation of the Safety and Efficacy of LNZ100 & LNZ101 for the Treatment of Presbyopia NCT05656027 | LENZ Therapeutics, Inc | Phase 3 |
| Unknown | Artificial Intelligent System for Eye Emergency Triage and Primary Diagnosis NCT05680090 | Sun Yat-sen University | — |
| Withdrawn | Development of an IT Tool Able to Identify Ocular Conditions NCT05973617 | Aston University | — |
| Active Not Recruiting | Repeated Low-Level Red-Light Therapy for Shortening Axial Length NCT05550740 | Shanghai Eye Disease Prevention and Treatment Center | N/A |
| Completed | Comparison of Subjective Refraction Measurement With SiVIEW Software and by an Expert NCT04185701 | SiVIEW | N/A |
| Unknown | Multimodal Equipment for Teleophthalmology Assessment (META) NCT05565547 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Completed | Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the NCT05431543 | LENZ Therapeutics, Inc | Phase 2 |
| Active Not Recruiting | A Phase 2b, Study of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED) NCT05276063 | Sling Therapeutics, Inc. | Phase 2 / Phase 3 |
| Unknown | Pistachios and Neural Macular Pigment NCT05283941 | Tufts University | N/A |
| Completed | Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the T NCT05294328 | LENZ Therapeutics, Inc | Phase 2 |
| Completed | Investigation of the Safety and Effectiveness of a Trifocal IOL NCT04176965 | Beaver-Visitec International, Inc. | N/A |
| Unknown | Effect of Repeated Low-Level Red-Light Therapy on Visual Field Damage in Primary Open-angle Glaucoma NCT05309811 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Unknown | Pediatric Eye Care Investigated Team NCT05247099 | Zhongshan Ophthalmic Center, Sun Yat-sen University | — |
| Recruiting | Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for NAION NCT05147701 | The Foundation for Orthopaedics and Regenerative Medicine | Phase 1 |
| Terminated | Study to Evaluate the Efficacy Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon NCT05176717 | Laboratoires Thea | Phase 2 / Phase 3 |
| Completed | A Study of Laquinimod Eye-drops in Healthy Participants NCT05187403 | Active Biotech AB | Phase 1 |
| Terminated | Study to Evaluate the Efficacy Safety and Tolerability of Ultevursen in Subjects With RP Due to Mutations in E NCT05158296 | Laboratoires Thea | Phase 2 / Phase 3 |
| Terminated | Effectiveness of Periocular Drug Injection in CATaract Surgery NCT05158699 | Luigi Rondas | Phase 3 |
| Completed | Manual Versus Automated Choroidal Thickness Measurements Using Swept-source Anterior Segment OCT NCT05211089 | Assiut University | — |
| Completed | FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial NCT04149210 | Massachusetts Eye and Ear Infirmary | Phase 3 |
| Completed | Efficacy and Safety of MCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE] NCT04945772 | Nanoscope Therapeutics Inc. | Phase 2 |
| Unknown | Ophthalmologic Evaluation of Patients With Obesity and Metabolic Syndrome Before and After Bariatric Surgery NCT04926714 | XiaoYong Liu | — |
| Terminated | Effect of Chitosan-N-acetylcysteine on Subjective Pain Sensation in Corneal Abrasion NCT05049642 | Vienna Institute for Research in Ocular Surgery | N/A |
| Terminated | Efficacy of Different Treatment Regimens With Chitosan-N- Acetylcysteine in Moderate-to-severe Dry Eye Disease NCT05053789 | Vienna Institute for Research in Ocular Surgery | N/A |
| Terminated | Effect of Chitosan-N-Acetylcysteine on IOL-power Prior to Cataract Surgery NCT05049629 | Vienna Institute for Research in Ocular Surgery | N/A |
| Unknown | Development of a Keratoconus Detection Algorithm by Deep Learning Analysis and Its Validation on Eyestar Image NCT04763785 | Insel Gruppe AG, University Hospital Bern | — |
| Recruiting | Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Seco NCT04663750 | King's College Hospital NHS Trust | Phase 3 |
| Completed | Effect on Ocular Surface Symptoms of Online Education NCT04960696 | Kahramanmaras Sutcu Imam University | — |
| Completed | Protection of Corneal Epithelium Using Chitosan-N-acetylcysteine Eye Drops During and/or After Cataract Surger NCT05064189 | Vienna Institute for Research in Ocular Surgery | N/A |
| Unknown | An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerabil NCT04855045 | ProQR Therapeutics | Phase 2 / Phase 3 |
| Unknown | Repeated Low-Level Red-Light Therapy and Orthokeratology in Fast-progressing Myopia Control NCT04722874 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Completed | Increasing Vision Center Service Utilization NCT04800718 | Seva Foundation | N/A |
| Unknown | Eye Shields for Infants After Dilated Exam NCT04519060 | Children's Hospital Los Angeles | N/A |
| Withdrawn | Assessment of COVID-19 in Tearfilm NCT04579458 | Vanderbilt University Medical Center | — |
| Completed | Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics NCT04289909 | Institut National de la Santé Et de la Recherche Médicale, France | N/A |
| Terminated | Tear Film SARS-nCoV-2 Detection in Symptomatic and Pauci-symptomatic Patients. NCT04799704 | Universitaire Ziekenhuizen KU Leuven | — |
| Completed | Deep Learning for Classification of Scheimpflug Corneal Tomography Images NCT04497207 | Assiut University | — |
| Completed | Pix2pix Networks for Scheimpflug Corneal Tomography Image Generation NCT04582253 | Assiut University | — |
| Completed | Determination of the Validity of a Questionnaire to Assess the Visual Function of Preverbal Children With Oper NCT04428541 | Fondation Ophtalmologique Adolphe de Rothschild | N/A |
| Completed | A Randomized Study of Smile Exercise for Dry Eye NCT04421300 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Completed | Brinzolamide-brimonidine Fixed Combination for Preventing IOP Elevation After Intravitreal Anti-VEGF Injection NCT04523844 | General Hospital of Athens Elpis | N/A |
| Active Not Recruiting | Rate of Progression in EYS Related Retinal Degeneration NCT04127006 | Jaeb Center for Health Research | — |
| Withdrawn | Mitochondrial DNA in Vitreous Fluid and Blood in Patients With Eye Disease or Ocular Trauma. NCT04334499 | The University of Texas Medical Branch, Galveston | — |
| Recruiting | The Role of Transscleral Cyclophotocoagulation in Patients Undergoing a Boston Keratoprosthesis NCT04232982 | Centre hospitalier de l'Université de Montréal (CHUM) | N/A |
| Completed | BCC Excision Revisited NCT05853315 | Medical University of Vienna | — |
| Completed | Correlation Between Exhaled Propofol Concentration With Plasma Concentration in Children NCT04150432 | Oslo University Hospital | N/A |
| Active Not Recruiting | A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigme NCT04123626 | ProQR Therapeutics | Phase 1 / Phase 2 |
| Active Not Recruiting | Manhattan Vision Screening and Follow-Up Study (NYC-SIGHT) NCT04271709 | Columbia University | N/A |
| Completed | Smarter Care Virginia, Examining Low-Value Care in Virginia NCT04053335 | University of California, Los Angeles | — |
| Unknown | Efficacy of Repeated Low-Level Red-Light Therapy in Myopia Control NCT04073238 | Zhongshan Ophthalmic Center, Sun Yat-sen University | N/A |
| Completed | Study to Collect Safety and ECG Data on Brolucizumab 6 mg Intravitreal Treatment in Patients With Wet AMD NCT03954626 | Novartis Pharmaceuticals | Phase 3 |
| Active Not Recruiting | Myopic Optic Neuropathy in Chinese High Myopia Population NCT04302220 | Sun Yat-sen University | — |
| Terminated | Extension Study to Study PQ-110-001 (NCT03140969) NCT03913130 | Laboratoires Thea | Phase 1 / Phase 2 |
| Active Not Recruiting | A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in NCT03913143 | ProQR Therapeutics | Phase 2 / Phase 3 |
| Completed | Photorefractive Intrastromal Crosslinking (PiXL) for the Treatment of Progressive Keratoconus NCT03990506 | Umeå University | N/A |
| Completed | Abatacept in Patients With Birdshot HLA A29 Uveitis NCT03871361 | Universitaire Ziekenhuizen KU Leuven | Phase 2 |
| Completed | Monitoring Drug-induced Uveitis NCT03899922 | Groupe Hospitalier Pitie-Salpetriere | — |
| Unknown | Epi-on PiXL for the Treatment of Progressive Keratoconus. NCT04668924 | Umeå University | N/A |
| Completed | Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the US NCT03780257 | ProQR Therapeutics | Phase 1 / Phase 2 |
| Completed | Prophylactic PRP in Moderate NPDR NCT05543564 | Assiut University | — |
| Unknown | Motivations and Barriers to Participating in Ophthalmology Research Projects NCT04404803 | Manchester University NHS Foundation Trust | — |
| Unknown | Identification and Measurement of Antioxidants and Cytokines in the Anterior Chamber of Various Ocular Disorde NCT04101591 | Chang Gung Memorial Hospital | — |
| Completed | Dafilon® Suture Material in Patients Undergoing Ophthalmic Surgery NCT05968443 | Aesculap AG | — |
| Completed | Transcutaneous Levator Recession for Non-thyroid Lid Retraction NCT05671120 | Al-Azhar University | N/A |
| Terminated | FOCUS: A Phase I/II First in Human Study to Evaluate the Safety and Efficacy of GT005 Administered in Subjects NCT03846193 | Gyroscope Therapeutics Limited | Phase 1 / Phase 2 |
| Completed | Tear Lipid Layer Thickness Changes With Use of Emollient and Non-Emollient Eye Drops NCT03706443 | Ohio State University | N/A |
| Unknown | DRy Eye Outcome and Prescription Study NCT03652415 | Guy's and St Thomas' NHS Foundation Trust | — |
| Completed | Deep Learning for Fluorescein Angiography and Optical Coherence Tomography Macular Thickness Map Image Transla NCT05105620 | Assiut University | — |
| Completed | Nasolacrimal Duct Obstruction NCT04931186 | Medical University of Vienna | — |
| Unknown | Automatic Self Transcending Meditation (ASTM) in Patients With Dry Eye Disease NCT03087006 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | N/A |
| Completed | The EXPLORE Study - The Use of Binocular OCT Imaging for the Assessment of Ocular Disease NCT03553017 | University College, London | — |
| Unknown | OMNI in Open-angle Glaucoma Treatment NCT04503356 | Centre of Postgraduate Medical Education | N/A |
| Completed | Photorefractive Intrastromal Corneal Crosslinking as a Treatment for Low Grade Myopia NCT03987880 | Umeå University | N/A |
| Completed | Self-adherent Wrap Techniques for Orbital Surgery NCT03415490 | Sun Yat-sen University | N/A |
| Recruiting | Shanghai Children and Adolescent Diabetes Eye Study NCT03587948 | Shanghai Eye Disease Prevention and Treatment Center | — |
| Completed | Natural History Study of CEP290-Related Retinal Degeneration NCT03396042 | Editas Medicine, Inc. | — |
| Unknown | Frequency Of Eye Problems In Type 2 Diabetes With Chronic Kidney Disease NCT03330054 | Mohammed Ramadan Abdallah | — |
| Completed | Comparison of Efficacy and Safety of Mitomycin and Aflibercept Used to Support Primary Trabeculectomy. NCT03766425 | Medical University of Lublin | EARLY_Phase 1 |
| Completed | VEGF Concentrations After Intravitreal Bevacizumab vs Ranibizumab as a Treatment for Type 1 ROP NCT03148132 | Universidad Autonoma de San Luis Potosí | Phase 4 |
| Completed | Vouchers to Increase Uptake of Already Free Eye Care NCT04426331 | Johns Hopkins University | N/A |
| Completed | Triton Agreement and Precision Study NCT03080714 | Topcon Medical Systems, Inc. | — |
| Completed | Efficacy and Safety of ab Interno Trabeculectomy With the Kahook Dual Blade NCT04202562 | Hospital San Carlos, Madrid | N/A |
| Terminated | Collagen Cross-Linking With Ultraviolet-A in Asymmetric Corneas NCT03029104 | Cxlusa | Phase 2 |
| Completed | KJ-TFC-004 Drug-drug Interaction Study NCT02967614 | Kukje Pharma | Phase 1 |
| Completed | Long-Term Follow-Up Gene Therapy Study for Leber Congenital Amaurosis OPTIRPE65 (Retinal Dystrophy Associated NCT02946879 | MeiraGTx UK II Ltd | — |
| Completed | Study for Collection of Aflibercept Data in Routine Practice NCT02811692 | Bayer | — |
| Completed | Feasibility Study of Retinal Screening Using the RetinaVue 100 Camera in Outpatient Dialysis Centers NCT02823600 | University of North Carolina, Chapel Hill | N/A |
| Completed | SD-OCT Multimodal Analysis in GLaucoma NCT02710916 | University Hospital, Bordeaux | N/A |
| Completed | Study Evaluating the Safety, Pharmacokinetics and Pharmacodynamics of OPT-302 With or Without Lucentis™ in Pat NCT02543229 | Opthea Limited | Phase 1 |
| Terminated | X-82 to Treat Age-related Macular Degeneration NCT02348359 | Tyrogenex | Phase 2 |
| Completed | Intravitreal Injections by Nurses and Physicians Compared NCT02359149 | St. Olavs Hospital | N/A |
| Recruiting | Adaptive Optics Retinal Imaging NCT02317328 | National Eye Institute (NEI) | — |
| Completed | Intraestromal Corneal Ring in Mild Keratoconus NCT03127163 | University of Sao Paulo | N/A |
| Completed | Sparing of the Fovea in Geographic Atrophy Progression NCT02332343 | University Hospital, Bonn | — |
| Recruiting | IRIS Registry: Intelligent Research in Sight Registry NCT02485847 | American Academy of Ophthalmology | — |
| Completed | Aflibercept After Ranibizumab in Exudative Age-related Macular Degeneration NCT02157077 | Centre Hospitalier Intercommunal Creteil | Phase 3 |
| Completed | Comparison of Non-mydriatic Camera Systems in a Female Health Hospital NCT02089009 | Dr. Martin Leitritz | N/A |
| Completed | Improving Follow-Up Adherence in a Primary Eye Care Setting NCT02001129 | Wills Eye | N/A |
| Completed | The Flashing Light-Induced Pupil Response (FLIPR) Glaucoma Study NCT01857440 | Ohio State University | — |
| Completed | Efficacy of Subantimicrobial Dose Doxycycline for Moderate to Severe and Active Graves' Orbitopathy NCT01727973 | Sun Yat-sen University | Phase 1 / Phase 2 |
| Unknown | An Open-label Study to Evaluate the Clinical and Economic Benefits of I-Ray in Patients With Choroidal Neovasc NCT01521065 | Oraya Therapeutics, Inc. | Phase 2 |
| Completed | Blood and Saliva Sample Collection for AREDS 2 NCT01553474 | National Eye Institute (NEI) | — |
| Completed | Ultrasound Guided Peribulbar Anaesthesia - A Novel Dual Quadrant Injection Technique NCT02459782 | Sunnybrook Health Sciences Centre | N/A |
| Completed | Safety and Efficacy Study of rAAV.sFlt-1 in Patients With Exudative Age-Related Macular Degeneration NCT01494805 | Lions Eye Institute, Perth, Western Australia | Phase 1 / Phase 2 |
| Completed | Intravitreal Ranibizumab Combined With Panretinal Photocoagulation in Patients With Proliferative Diabetic Ret NCT01746563 | University of Sao Paulo | Phase 1 / Phase 2 |
| Completed | Efficacy and Safety of Oral Valproic Acid for Retinitis Pigmentosa NCT01399515 | Seoul National University Hospital | Phase 2 |
| Terminated | Study of 2.0 mg Ranibizumab in Subjects With Ischemic Central Retinal Vein Occlusion (RAVE2) NCT01225146 | David M. Brown, M.D. | Phase 1 |
| Completed | Safety And Tolerability Study Of RN6G In Subjects With Advanced Dry, Age-Related Macular Degeneration Includin NCT01003691 | Pfizer | Phase 1 |
| Completed | Safety and Tolerability Study of AAV2-sFLT01 in Patients With Neovascular Age-Related Macular Degeneration (AM NCT01024998 | Genzyme, a Sanofi Company | Phase 1 |
| Completed | INTREPID - IRay Plus Anti-VEGF Treatment For Patients With Wet AMD NCT01016873 | Oraya Therapeutics, Inc. | Phase 2 |
| Completed | Creation of the Biobank Related to Eye Disease NCT01240343 | Kimberly Drenser | — |
| Completed | A Prospective, Unmasked Evaluation of the iStent in Patients With Primary Open-Angle Glaucoma NCT00911924 | Glaukos Corporation | Phase 4 |
| Completed | Evaluation of the iStent Versus Two Ocular Hypotensive Agents in Patients With Primary Open-angle Glaucoma (PO NCT00913029 | Glaukos Corporation | Phase 4 |
| Completed | Safety And Tolerability Study Of RN6G In Patients With Dry, Age-Related Macular Degeneration NCT00877032 | Pfizer | Phase 1 |
| Recruiting | Screening for Research Participants NCT00655096 | National Eye Institute (NEI) | — |
| Unknown | Safety & Tolerability of the IRay System in Subjects With Exudative Choroidal Neovascularization (CNV) Seconda NCT01217762 | Oraya Therapeutics, Inc. | Phase 1 |
| Completed | Evaluation and Treatment of People With Eye Diseases NCT00708955 | National Eye Institute (NEI) | — |
| Completed | Treatment of Pseudovitellium Detachment With Open-Label Anecortave Acetate Sterile Suspension (15 mg) NCT00211432 | Manhattan Eye, Ear & Throat Hospital | Phase 2 |
| Unknown | Visual Performance of Pseudophakic Patient With Different Intraocular Lenses NCT01763411 | Hospital Oftalmologico de Brasilia | — |
| Completed | The Effect of Amlodipine and Lisinopril on Retinal Autoregulation in Type 1 Diabetes NCT00337298 | University of Aarhus | N/A |
| Completed | Anecortave Acetate for Treatment of Steroid Induced Intraocular Pressure (IOP) Elevation NCT00315640 | Alcon Research | Phase 2 |
| Completed | Next Generation Ophthalmic Irrigating Solution Posterior Segment Study NCT00333203 | Alcon Research | Phase 3 |
| Unknown | Effect of Percutaneous Botulinum Toxin A Injection on Natural Course of Upper Lid Retraction in Thyroid Eye Di NCT00370734 | Shahid Beheshti University of Medical Sciences | Phase 2 / Phase 3 |
| Completed | Clinical and Genetic Studies of Familial Exudative Vitreoretinopathy NCT00106756 | National Eye Institute (NEI) | — |
| Completed | Intravitreal Microplasmin in Patients Undergoing Surgical Vitrectomy NCT00123279 | ThromboGenics | Phase 2 |
| Completed | Single Dose of 1% Tropicamide and 10% Phenylephrine for Pupillary Dilation NCT00120432 | Khon Kaen University | Phase 3 |
| Completed | Screening for Research Subjects With Anterior Segment Diseases NCT00088348 | National Eye Institute (NEI) | — |
| Completed | Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases NCT00076271 | National Eye Institute (NEI) | — |
| Completed | Analyses of Existing Framingham Data NCT00342810 | National Eye Institute (NEI) | — |
| Completed | Immune Responses to Antigens in Non-infectious Eye Inflammatory Diseases NCT00357071 | National Eye Institute (NEI) | — |
| Unknown | Testing of Innocuousness of Benzalkonium Chloride on the Eye Concerning Possible Growth of Langerhans Cells NCT00414739 | University of Rostock | Phase 1 |