Clinical Trials Directory

Trials / Completed

CompletedNCT05728944

Phase 3 Efficacy Study of LNZ100 & LNZ101 for the Treatment of Presbyopia

A Multi-Center, Double-Masked Phase 3 Evaluation of the Safety and Efficacy of LNZ101 for the Treatment of Presbyopia

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
229 (actual)
Sponsor
LENZ Therapeutics, Inc · Academic / Other
Sex
All
Age
45 Years – 75 Years
Healthy volunteers
Accepted

Summary

Phase 3 Efficacy Study to evaluate the Safety and Efficacy of LNZ100 \& LNZ101 for the Treatment of Presbyopia

Detailed description

Phase 3 study to evaluate the safety and effectiveness of LNZ101 compared with LNZ100 and Vehicle for the treatment of Presbyopia.

Conditions

Interventions

TypeNameDescription
DRUGAceclidine+Brimonidine combination ophthalmic solutionAceclidine + Brimonidine combination ophthalmic solution
DRUGAceclidine ophthalmic solutionAceclidine ophthalmic solution
DRUGVehicleProprietary vehicle ophthalmic solution

Timeline

Start date
2023-03-06
Primary completion
2023-12-14
Completion
2024-01-24
First posted
2023-02-15
Last updated
2026-02-25
Results posted
2026-02-25

Locations

17 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05728944. Inclusion in this directory is not an endorsement.