Presbyopia

298 registered clinical trials studyying Presbyopia — 25 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Contralateral Claims Study of Clareon Vivity Pro NCT07484191	Alcon Research	N/A
Not Yet Recruiting	Comparison of PRESBYOND Laser Blended Vision and Conventional Monovision LASIK in Individuals With Presbyopia: NCT07512089	Zhongshan Ophthalmic Center, Sun Yat-sen University	N/A
Recruiting	Performance of Two Daily Disposable Multifocal Contact Lenses NCT07444658	CooperVision International Limited (CVIL)	N/A
Recruiting	Comfort and Vision With TOTAL30 Multifocal Lenses NCT07284966	Scripps Poway Eyecare and Optometry	—
Recruiting	Presbyopic Wear Experience With Multifocal Lenses Compared to Single Vision Lenses and Reading Glasses NCT07218731	Ohio State University	N/A
Recruiting	Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections With EDOF IO NCT07077967	Democritus University of Thrace	—
Active Not Recruiting	Post Market Clinical Evaluation of Clareon PanOptix Pro and Clareon PanOptix Pro Toric IOLs NCT07161635	Alcon Research	N/A
Not Yet Recruiting	Open Label, Multi-center, Phase I Study of TECLens Quantitative Refractive Crosslinking in Presbyopia-Aged Pat NCT07208604	TECLens, Inc.	N/A
Completed	The Development of New Functions of Esculin and Digitalis Glycosides Eye Drops: A Study on the Treatment of Pr NCT07151612	Shanxi Eye Hospital	Phase 4
Not Yet Recruiting	Quantitative Refractive Crosslinking in Presbyopia Aged Patients NCT07137767	TECLens, Inc.	N/A
Completed	Pilot Dispensing Study of Two Marketed Daily Disposable Multifocal Contact Lenses NCT07076160	Johnson & Johnson Vision Care, Inc.	N/A
Recruiting	Quality of Life in Presbyopic Patients Who Are Treated With Qlosi NCT07113210	Southern College of Optometry	Phase 4
Withdrawn	Evaluation of AcrySof IQ Vivity Extended Vision Intraocular Lenses NCT06541795	Alcon Research	N/A
Not Yet Recruiting	Evaluation of Refractive Outcomes in Patients Undergoing PRESBYOND Using the MEL90 Excimer Laser NCT06960785	Carl Zeiss Meditec AG	—
Completed	Comparative Study and Validation of New Methodologies for Measuring Addition NCT06963138	Essilor International	N/A
Recruiting	Efficacy and Safety of BRIMOCHOL PF and CARBACHOL PF in Chinese Presbyopia Patients NCT06948357	Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.	Phase 2
Not Yet Recruiting	Evaluation of Safety and Effectiveness of an IOL With a Virtual Aperture Optic NCT05955846	Z Optics, Inc.	N/A
Not Yet Recruiting	The Effects of Glasses-Free 3D Training on Visual and Cognitive Function in Presbyopic Individuals NCT06853691	Zhongshan Ophthalmic Center, Sun Yat-sen University	N/A
Completed	A Clinical Comparison of Proclear® 1 Day Multifocal and Clariti® 1 Day Multifocal 3 Add NCT06869044	CooperVision International Limited (CVIL)	N/A
Completed	Impact of Red Light Therapy on Alleviating Visual Fatigue in Presbyopes NCT06745661	The Hong Kong Polytechnic University	N/A
Recruiting	North American Comfilcon A Clinical Study NCT06902584	CooperVision International Limited (CVIL)	—
Recruiting	"My Eyes, My Light": Amar Chokh, Amar Alo NCT07135570	Data Yakka, Inc.	—
Not Yet Recruiting	Accommodation-Related Visual Training Combined with Transcranial Electrical Stimulation Versus Visual Training NCT06714890	Eye & ENT Hospital of Fudan University	N/A
Not Yet Recruiting	Quality of Life in Presbyopes Using Single-vision Lens and Progressive Lens Correction NCT06699784	The Hong Kong Polytechnic University	N/A
Terminated	DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study NCT06483113	Alcon Research	—
Recruiting	Phase III Presbyopia Correction Using the VIS Opti-K™ System NCT06487897	VIS, Inc.	Phase 3
Not Yet Recruiting	The VIS Opti-K Low Vision Aid Device Provides Vision Improvement. NCT06597292	VIS, Inc.	N/A
Completed	Evaluate Efficacy and Safety of POS to Improve Distance-corrected Near Visual in Participants With Presbyopia NCT06542497	Ocuphire Pharma, Inc.	Phase 3
Completed	Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses NCT06461455	Alcon Research	N/A
Completed	Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses NCT06469242	Alcon Research	N/A
Not Yet Recruiting	Safety and Efficacy Study of Pilocarpine HCl Ophthalmic Solution in Participants With Presbyopia NCT06451666	CSPC Ouyi Pharmaceutical Co., Ltd.	Phase 3
Completed	Clareon PanOptix Pro vs. Clareon PanOptix - Study B NCT06401551	Alcon Research	N/A
Completed	Clareon PanOptix Pro vs. Clareon PanOptix - Study A NCT06400745	Alcon Research	N/A
Completed	Evaluation of Long-term Safety and Performance of PanOptix Trifocal Intraocular Lens (IOL) NCT06166901	Alcon Research	N/A
Completed	Visual Performance of Dailies Total1 Multifocal and Acuvue Oasys Max 1-Day Multifocal in Presbyopic Lens Weare NCT06369987	University of Waterloo	N/A
Completed	A Clinical Comparison of Two Multifocal Toric Soft Contact Lenses NCT06438601	CooperVision, Inc.	N/A
Completed	Evaluation of the Visual Acuity Curves of an Enhanced Monofocal Intraocular Lens NCT07439835	Democritus University of Thrace	—
Completed	Safety, Tolerability and Pharmacokinetics of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Chinese W NCT06270030	Corxel Pharmaceuticals	Phase 1
Completed	Performance Comparison of Two Monthly Replacement Silicone Hydrogel Multifocal Lens Types NCT06232590	CooperVision International Limited (CVIL)	N/A
Completed	Refitting Multifocal Contact Lens Wearers With a Different Multifocal Contact Lens NCT06328660	CooperVision International Limited (CVIL)	N/A
Completed	Safety and Efficacy of an Intrastromal Transform Corneal Allograft (TCA) for Presbyopia Correction - Long Term NCT06310252	Allotex, Inc.	—
Unknown	Identification of Minimum Focal Points in Vision Curve Formation NCT06260852	Democritus University of Thrace	—
Completed	Visual Outcomes After Extended Depth of Focus Intraocular Lens Implantation With and Without Digital Assistanc NCT06460389	Democritus University of Thrace	—
Active Not Recruiting	Transforming Households With Refraction and Innovative Financial Technology NCT05510687	Queen's University, Belfast	N/A
Completed	Clinical Outcomes of Femtosecond Laser Presbyopia Treatment in Monofocal IOLs NCT07384182	Perfect Lens, LLC	N/A
Unknown	Using the VisuMax Femtosecond Laser System to Perform SMILE Optimized for Presbyopia by Modulation of Postoper NCT05684237	London Vision Clinic	N/A
Completed	Evaluation of Soft Multifocal Lenses in Presbyopic Previous Contact Lens Wearers NCT06053463	Jennifer Fogt	N/A
Completed	Evaluation of the Efficacy and Safety of LNZ101 and LNZ100 for the Presbyopia NCT06045299	Corxel Pharmaceuticals	Phase 3
Active Not Recruiting	Post Market Clinical Follow-up (PMCF) Study of Clareon Vivity & Clareon PanOptix NCT05796453	Alcon Research	N/A
Recruiting	IC-8 Apthera IOL New Enrollment Post Approval Study NCT06060041	Bausch & Lomb Incorporated	—
Recruiting	PROductivity Study of Presbyopia Elimination in Rural-dwellers II NCT04629820	Queen's University, Belfast	N/A
Completed	MULTICENTER, DOUBLE-ARM, PATIENT AND ASSESSOR-MASKED, PROSPECTIVE, RANDOMIZED CLINICAL TRIAL TO COMPARE VISUAL NCT07385014	Milton S. Hershey Medical Center	N/A
Completed	Plasma Pharmacokinetics and Safety of LNZ101 and LNZ100 Ophthalmic Solutions in Healthy Adult Subjects With Pr NCT05936489	LENZ Therapeutics, Inc	Phase 1
Completed	Comparison of Two Different Optical Biometric Systems NCT05411341	Democritus University of Thrace	—
Completed	Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lens NCT05886907	Alcon Research	N/A
Not Yet Recruiting	Clinical Study to Evaluate the LensGen® Juvene® Intraocular Lens NCT05364983	LensGen, Inc.	N/A
Completed	Phase 3 Efficacy Study of LNZ100 & LNZ101 for the Treatment of Presbyopia NCT05728944	LENZ Therapeutics, Inc	Phase 3
Completed	Phase 3 Safety Study for the Treatment of Presbyopia Subjects NCT05753189	LENZ Therapeutics, Inc	Phase 3
Completed	A Clinical Comparison of Two Soft Multifocal Contact Lenses NCT05794126	CooperVision, Inc.	N/A
Completed	Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses NCT05702541	Alcon Research	N/A
Completed	Post-approval Follow-up Study of the IC-8 Apthera Intraocular Lens (IOL) NCT05758883	AcuFocus, Inc.	—
Unknown	Ocular Biomarkers for Successful Premium Trifocal Intra-ocular Lenses Implantation NCT05863247	Hospital dos Lusíadas	—
Completed	Study Assessing the Efficacy and Safety of STN1013600 Ophthalmic Solution 0.1% and 0.3% Compared With Placebo NCT05665387	Santen Inc.	Phase 2
Completed	Safety and Efficacy of Nyxol Eye Drops as a Single Agent and With Adjunctive Low-Dose Pilocarpine Eye Drops in NCT05646719	Ocuphire Pharma, Inc.	Phase 3
Completed	Phase 3 Evaluation of the Safety and Efficacy of LNZ100 & LNZ101 for the Treatment of Presbyopia NCT05656027	LENZ Therapeutics, Inc	Phase 3
Completed	Performance Evaluation of Different Daily Disposable Multifocal Contact Lenses NCT05763628	CooperVision, Inc.	N/A
Withdrawn	Using AGN-190584 in Subjects Utilizing Single -Use Daily, Contact Lenses NCT05624320	Gordon Schanzlin New Vision	Phase 4
Completed	The Effect of Orally Administered Extracts of Chokeberry, Kamchatka Berry and Blueberry on the Condition of th NCT07382882	Wroclaw Medical University	N/A
Completed	Retrospective Clinical Investigation of the Safety and Performance of 640PM Trifocal IOL Implantation in Patie NCT05735990	Medicontur Medical Engineering Ltd	—
Completed	Symfony/Synergy IOL Combination Outcomes NCT05604781	Center For Sight	—
Unknown	Prospective Multicenter Clinical Study on the Visual and Refractive Outcomes and Safety Outcomes Following Imp NCT05596682	Medicontur Medical Engineering Ltd	—
Completed	Multifocal Contact Lenses Fitting Methods Comparison NCT05734846	CooperVision, Inc.	N/A
Completed	Evaluating Two Multifocal Daily Disposable Contact Lenses NCT05579886	CooperVision, Inc.	N/A
Unknown	Comparison of Two Aspheric Intraocular Lenses for Micro-monovision NCT05531110	Guy's and St Thomas' NHS Foundation Trust	N/A
Completed	Extended Depth of Focus Contact Lenses for Presbyopia NCT05495971	Visioneering Technologies, Inc	N/A
Unknown	Comparison of Aspheric Toric Intraocular Lenses for Micro-monovision NCT05506553	Guy's and St Thomas' NHS Foundation Trust	N/A
Completed	A Clinical Evaluation of a Phakic Intraocular Lens NCT07291739	Staar Surgical Company	N/A
Completed	Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the NCT05431543	LENZ Therapeutics, Inc	Phase 2
Completed	Comparison of Premium Monovision and Bilateral Implantation of Trifocal Diffractive Intraocular Lenses NCT05494177	Democritus University of Thrace	—
Completed	Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex C NCT05574270	AcuFocus, Inc.	N/A
Unknown	Efficacy of Pilocarpine 1% in Presbyopia NCT05578001	Isfahan University of Medical Sciences	Phase 3
Completed	Clinical Evaluation of Two Multifocal Contact Lenses NCT05457608	CooperVision, Inc.	N/A
Withdrawn	Study of AGN-190584 Eye Drops to Assess Safety and Efficacy in Participants Aged 40-80 Years With Pseudophakic NCT05393089	Allergan	Phase 2
Completed	Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses NCT05338333	Alcon Research	N/A
Active Not Recruiting	PROductivity Study of Presbyopia Elimination in Rural-dwellers III NCT04654013	Queen's University, Belfast	N/A
Completed	Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the T NCT05294328	LENZ Therapeutics, Inc	Phase 2
Completed	An Evaluation of the Safety of CSF-1 in Presbyopic Subjects NCT05393895	Orasis Pharmaceuticals Ltd.	Phase 3
Completed	Safety and Efficacy Study BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic or Pseudophakic Pr NCT05270863	Visus Therapeutics	Phase 3
Completed	Clinical Evaluation and Comparison of the Tecnis Symfony Optiblue and Tecnis Symfony IOLs NCT06567834	Empire Eye and Laser Center	N/A
Completed	Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophaki NCT05135286	Visus Therapeutics	Phase 3
Completed	Synergy Lens Outcomes Evaluation NCT05418153	Center For Sight	—
Completed	1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia NCT05325931	Bausch & Lomb Incorporated	N/A
Completed	Evaluation of Visual Outcomes in Patients With Complex Corneas Implanted With the IC-8 IOL NCT05377515	AcuFocus, Inc.	—
Completed	Safety and Efficacy of Pilocarpine Ophthalmic Topical Cream for the Treatment of Presbyopia NCT05124275	Glaukos Corporation	Phase 2
Unknown	RayOne EMV Mini-monovision - Efficiency and Safety of 3 Grades of Mini-monovision NCT05417633	Somich, s.r.o.	N/A
Completed	Assessment of Three Basic Progressive Lens Designs NCT05252871	Western University of Health Sciences	N/A
Active Not Recruiting	Clinical Trial With Artiflex Presbyopic (Artiplus) NCT04632784	Ophtec BV	N/A
Completed	Safety & Efficacy of Pilocarpine Ophthalmic Spray for Temporary Improvement of Near Vision in Presbyopic Adult NCT05114486	Eyenovia Inc.	Phase 3
Withdrawn	Implantation of a Trifocal Hydrophobic IOL in Patients That Underwent Refractive Surgery NCT04054427	Beaver-Visitec International, Inc.	N/A
Completed	Evaluating the Success of Habitual Multifocal Wearers When Refit With a New Lens Design NCT04952701	CooperVision, Inc.	N/A
Completed	Monofocal IOL Visual Outcomes When Targeting Mini Monovision NCT05069415	Carolina Eyecare Physicians, LLC	N/A
Completed	The Impact of Light Conditions on the Efficacy of Multifocal Intraocular Lens Implantation in Activities of Da NCT05359380	Democritus University of Thrace	—
Completed	Pilot Clinical Investigation of Adaptative Eyeglasses for the Correction of Presbyopia NCT05326607	Laclaree	N/A
Completed	A Study to Assess Safety and Efficacy in Participants Age 40 to 55 With Presbyopia (Old Eye) Who Receive AGN-1 NCT04983589	Allergan	Phase 3
Completed	Impact of Personality on Satisfaction Following Presbyopic Correction NCT05191329	Democritus University of Thrace	—
Unknown	Pilocarpine, Brimonidine, Oxymetazoline (PBO) Compound to Control Presbyopia Symptoms NCT05006911	Optall Vision	Phase 1
Unknown	Comparison of a Compound With Pilocarpine and Brimonidine to Improve Near Vision in Healthy Presbyopic Patient NCT05001243	Optall Vision	Phase 1
Terminated	A Dose-ranging Study to Evaluate the Safety and Efficacy of UNR844 in Subjects With Presbyopia. NCT04806503	Novartis Pharmaceuticals	Phase 2
Withdrawn	Real-World Study of Vivity Intraocular Lenses (IOLs) NCT04800016	Alcon Research	N/A
Completed	A Study to Assess the Impact and Adverse Events of Topical Eyedrops of AGN-190584 on Night-driving Performance NCT04837482	AbbVie	Phase 3
Completed	APIOC for Presbyopia and APIOC for Presbyopia With Astigmatism NCT04883099	Lentechs, LLC	N/A
Terminated	Safety & Efficacy of the Laser Scleral Microporation Procedure NCT05068479	ACE Vision Group, Inc.	N/A
Completed	Post-Market Clinical Study of the PanOptix Intraocular Lens (IOL) in a Chinese Population NCT04755231	Alcon Research	N/A
Completed	Safety and Efficacy Study of BRIMOCHOL™, BRIMOCHOL™ F, and Carbachol in Subjects With Emmetropic Phakic and Ps NCT04774237	Visus Therapeutics	Phase 2
Completed	Visual Results of the Acrysof IQ Vivity Toric Extended Vision Intraocular Lens NCT04652037	Centre hospitalier de l'Université de Montréal (CHUM)	N/A
Completed	Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia NCT04675151	Ocuphire Pharma, Inc.	Phase 2
Unknown	Perceptions of Ophthalmologists Regarding Contemporary Presbyopia Management. NCT04733014	Democritus University of Thrace	—
Completed	The C-MAC Video Laryngoscope Helps Presbyopic Anesthetists NCT06581705	Egymedicalpedia	N/A
Completed	Vivity Outcomes in Patients With Early Stage Glaucoma NCT04670575	Vance Thompson Vision	—
Completed	Exploratory Clinical Study for Techniques Associated With the Fluid Accommodating IOL NCT04330001	Alcon Research	N/A
Completed	Safety & Efficacy of Pilocarpine Eye Solutions for Temporary Improvement of Near Vision in Presbyopic Adults NCT04657172	Eyenovia Inc.	Phase 3
Completed	Development and Validation of an Internet-based Near and Intermediate-vision Reading Test NCT04618224	Democritus University of Thrace	—
Completed	Comparative Analysis of the Visual Performance and Patient Satisfaction After Cataract Surgery With Implantati NCT06642779	Medicontur Medical Engineering Ltd	—
Unknown	Level of Agreement Between Clinical Defocus Curves and the Web-based Democritus Digital Acuity Reading Test wD NCT04739085	Democritus University of Thrace	—
Completed	Single-center, Double-arm, Prospective Clinical Trial to Compare Visual Performance of Non-diffractive Extende NCT04591054	Milton S. Hershey Medical Center	N/A
Unknown	Clinical Outcomes With a New Monofocal IOL Enhanced for Intermediate Vision NCT04904887	Dar Al Shifa Hospital	N/A
Completed	Clinical Investigation of the Multifocal IOL POD F GF in Cataracteous Eyes NCT04699266	Beaver-Visitec International, Inc.	N/A
Completed	An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-2) NCT04599972	Orasis Pharmaceuticals Ltd.	Phase 3
Completed	Assessment of Progressive Lens Designs NCT04734522	University of Milano Bicocca	N/A
Completed	An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-1) NCT04599933	Orasis Pharmaceuticals Ltd.	Phase 3
Active Not Recruiting	Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement NCT04570579	Alanna Nattis, DO	—
Completed	Vivity IOL: Emmetropia Compared to Monovision. NCT05464732	Carolina Eyecare Physicians, LLC	N/A
Completed	The Visual Performances of a Progressive Multifocal Intraocular Lens With Extended Depth of Focus NCT02740010	SIFI SpA	—
Unknown	Study of Presbyopia-correcting Intraocular Lenses in Eyes With Previous Corneal Refractive Surgery NCT04522427	Eye & ENT Hospital of Fudan University	N/A
Completed	Comparing Biofinity Toric Multifocal to Ultra Multifocal for Astigmatism NCT04404725	CooperVision, Inc.	N/A
Completed	Comparing the Performance of 1 Day Multifocal Contact Lenses NCT04449263	CooperVision, Inc.	N/A
Terminated	Phase 1/2 Study of AGN-241622 in Healthy Participants and Participants With Presbyopia NCT04403763	AbbVie	Phase 1 / Phase 2
Completed	Validation of an Activities-of-daily-living Framework at Different Light Conditions NCT05005624	Democritus University of Thrace	—
Completed	Compound to Control Presbyopia Symptoms NCT05006898	Optall Vision	Phase 1
Unknown	Prospective Clinical Study of Different Intraocular Lens Implantation Designed for the Correction of Presbyopi NCT04265846	Peking University Third Hospital	—
Active Not Recruiting	Evaluation of Safety and Efficacy of Intrastromal Implantation of CorVision® Bioengineered Corneal Inlay for C NCT04465409	LinkoCare Life Sciences AB	N/A
Unknown	Clinical Outcome of Extended-depth-of-focus Intraocualr Lens (SAV) Implantation NCT04391972	Samsung Medical Center	N/A
Completed	Clinical Outcome of Extended-depth-of-focus Trifocal Intraocualr Lens (Triumf) Implantation NCT04392024	Samsung Medical Center	N/A
Completed	Luminous Efficiency Function V(λ)' of Patients That Underwent Pseudophakic Presbyopic Corrections NCT04263636	Democritus University of Thrace	—
Not Yet Recruiting	Productivity Study of Presbyopia Improvement in Textile Workers NCT04172935	Zhongshan Ophthalmic Center, Sun Yat-sen University	N/A
Completed	Clinical Investigation of the Vision-R800 Device. NCT04208750	Pete Kollbaum, OD, PhD	Phase 4
Completed	Evaluation of a Reusable Silicone Hydrogel Multifocal Contact Lens NCT04189224	Johnson & Johnson Vision Care, Inc.	N/A
Terminated	A Clinical Study to Evaluate The Safety and Effectiveness of The RxSight Light Adjustable Lens (LAL) In Subjec NCT04177771	RxSight, Inc.	—
Completed	Apioc Presbyopic Contact Lens NCT04437732	Lentechs, LLC	N/A
Completed	Analysis of Defocus Curve of Pre-Presbyopic and Emerging Presbyopic Patients NCT04474782	Vance Thompson Vision	—
Completed	Safety & Efficacy of the Laser Scleral Microporation Procedure (Philippines) NCT04151550	ACE Vision Group, Inc.	N/A
Completed	Visual Outcomes After Presbyopic Lens Exchange NCT03790592	Carl Zeiss Meditec AG	N/A
Completed	A Study of Safety and Efficacy of UNR844 Chloride (UNR844-Cl) Eye Drops in Subjects With Presbyopia. NCT03809611	Novartis Pharmaceuticals	Phase 2
Terminated	Safety & Efficacy of the Laser Scleral Microporation Procedure (Taiwan) NCT04151446	ACE Vision Group, Inc.	N/A
Completed	Development and Validation of a Digital Optotype for Near Vision in Greek Language. NCT04242836	Democritus University of Thrace	—
Active Not Recruiting	Clinical Study to Investigate Outcomes of Trifocal Toric IOL POD FT in Asian Eyes NCT03844828	Beaver-Visitec International, Inc.	N/A
Completed	Smart Autofocusing Eyeglasses NCT03911596	University of Utah	—
Completed	A Phase 3 Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia NCT03857542	Allergan	Phase 3
Completed	A Multi-Center, Double-Masked Evaluation of the Efficacy and Safety of CSF-1 in the Treatment of Presbyopia NCT03885011	Orasis Pharmaceuticals Ltd.	Phase 2
Terminated	Non-Inferiority Study Comparing MINI WELL READY® and FineVision® in Patients With Cataract Surgery NCT03060954	SIFI SpA	N/A
Unknown	Pilocarpine and Brimonidine in Patients With Monofocal Lenses NCT03825081	Massachusetts Eye and Ear Infirmary	EARLY_Phase 1
Completed	Objective and Subjective Outcomes of a Trifocal IOL in Eyes With Different AL NCT05431868	Peking University Third Hospital	—
Completed	Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia NCT03804268	Allergan	Phase 3
Terminated	Multifocal Visual Performance Study NCT03757039	Alcon Research	N/A
Completed	Tecnis ZLB00 & Symfony Intraocular Lens Combination Outcomes NCT03771274	Carolina Eyecare Physicians, LLC	N/A
Completed	Clinical Evaluation of a Small Aperture Extended Depth of Focus Intraocular Lens NCT03633695	AcuFocus, Inc.	N/A
Completed	Long Term Follow-up of the VisAbility™ Micro Insert System for Presbyopic Patients NCT03811249	Refocus Group, Inc.	N/A
Completed	Post Approval Study of the AcrySof® IQ ReSTOR® Toric IOLs NCT03733730	Alcon Research	N/A
Completed	A Clinical Evaluation of the LensGen Intraocular Lens NCT05364658	LensGen, Inc.	N/A
Completed	Comparison of Clinical Outcomes POD L GF vs POD F GF in Asian Eyes NCT03688425	Beaver-Visitec International, Inc.	N/A
Withdrawn	Safety and Efficacy of a Sub-epitheilal Transform™ Corneal Allograft (TCA) for Presbyopia Correction NCT03675438	Allotex, Inc.	N/A
Completed	Apioc Contact Lens Feasibility NCT03688672	Lentechs, LLC	N/A
Terminated	Safety and Efficacy of an Intrastromal Transform™ Corneal Allograft (TCA) for Presbyopia Correction NCT03671135	Allotex, Inc.	N/A
Completed	Bifocal Contact Lens Study for Adults With Age-Related Near Vision Loss NCT03653715	Clerio Vision, Inc.	N/A
Unknown	Post-Approval Study With the KAMRA Inlay NCT03173664	AcuFocus, Inc.	—
Completed	Comparison of Clinical Outcomes POD L GF vs POD F GF (PHY1707) NCT03688399	Beaver-Visitec International, Inc.	N/A
Completed	A Feasibility Study to Assess the Visual Performance and Comfort of Hanita G4 Multifocal Soft Contact Lenses f NCT04841941	Hanita Lenses	N/A
Completed	Clinical Evaluation of Investigational Multifocal Toric Contact Lenses NCT03519282	CooperVision, Inc.	N/A
Completed	Clinical Performance of a Phakic Intraocular Lens (IOL) NCT03499821	Staar Surgical Company	N/A
Completed	Visual Performance, Patient Satisfaction and PCO Rate After Implantation of a Trifocal Hydrophobic IOL NCT03306342	Beaver-Visitec International, Inc.	N/A
Completed	Clinical Validation Study of Comfilcon A Multifocal Toric Contact Lenses NCT03417557	CooperVision, Inc.	N/A
Completed	Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Intraocular Lens (IOL) in a Korean Popu NCT03268746	Alcon Research	N/A
Completed	A Comparison of FineVision Intraocular Lenses vs Symfony Intraocular Lenses NCT03974451	Beaver-Visitec International, Inc.	N/A
Completed	Premium Monovision Versus Other Types of Monovision and Bilateral Trifocal Implantation. NCT04618380	Democritus University of Thrace	—
Completed	Clinical Evaluation of DAILIES TOTAL 1® Multifocal Compared to 1-Day Acuvue® Moist® Multifocal in a Japanese P NCT03341923	Alcon Research	N/A
Unknown	A Study to Evaluate the Raindrop Near Vision Inlay Under Flap or Within Pocket NCT03376412	Whitten Laser Eye	Phase 4
Completed	IOL Implantation After KAMRA Inlay Removal NCT03320473	AcuFocus, Inc.	N/A
Completed	Comparison of Clinical Outcomes on Trifocal IOLs FineVision POD F GF and FineVision POD F in Asian Eyes NCT03306355	Beaver-Visitec International, Inc.	N/A
Completed	Premium Trifocal IOL Comparative Analysis NCT04875455	Beaver-Visitec International, Inc.	N/A
Completed	Evaluation of Long-Term Clinical Acceptability and Satisfaction With the IC-8 Intraocular Lens NCT03314766	AcuFocus, Inc.	—
Terminated	A Study Raindrop Near Vision Inlay in Presbyopes Implanted in Corneal Pockets NCT03326869	Eye Center of North Florida	N/A
Completed	Clinical Study to Compare Visual Performance of Two Trifocal IOLs NCT03347981	Beaver-Visitec International, Inc.	N/A
Completed	Somofilcon A 1-Day Multifocal Study - Real World Subjective Acceptance Study NCT03519919	CooperVision, Inc.	N/A
Completed	PROductivity Study of Presbyopia Elimination in Rural-dwellers (PROSPER) NCT03228199	Congdon Nathan	N/A
Terminated	Compare Visual Outcomes Using a New Diagnostic Device NCT04037631	Carl Zeiss Meditec AG	—
Completed	Assessment of Near Vision Capacity in Different Light Conditions Following Bilateral Trifocal Intraocular Impl NCT03226561	Democritus University of Thrace	N/A
Unknown	A Prospective Study to Evaluate the Raindrop Near Vision Inlay With Mitomycin C NCT03242317	Fichte, Endl & Elmer Eyecare	Phase 4
Completed	Assessing Fitting Guides in Alcon Multifocal Contact Lenses NCT03118934	Alcon Research	N/A
Completed	Reading Glass on Livelihoods and Quality of Life in Rural Bangladesh NCT03719196	Brac	N/A
Completed	A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to M NCT03201562	LENZ Therapeutics, Inc	Phase 2
Unknown	A Prospective Study to Evaluate the Raindrop Near Vision Inlay in Presbyopic Patients With Treatments to Optim NCT03126877	Whitten Laser Eye	Phase 4
Unknown	Prospective Clinical Trial of Unilateral or Bilateral Implantation of TecnisSymfony IOL in Cataract Patients W NCT03501654	Seoul National University Hospital	N/A
Terminated	A Prospective Study To Evaluate The Raindrop Near Vision Inlay In Presybopic or Pseudophakic Patients Treated NCT03101501	Key-Whitman Eye Center	Phase 4
Completed	A Randomised Evaluation of Visual Function After Bilateral Implantation of Two Types of Presbyopia-correcting NCT03117426	Maastricht University Medical Center	N/A
Completed	Assessment of Near Vision Capacity in Different Light Intensities NCT03024073	Democritus University of Thrace	—
Unknown	Functional Assessment of ADL in Patients Who Underwent Bifocal and Trifocal Presbyopic Correction NCT03021512	Democritus University of Thrace	—
Completed	OPTI-FREE® PureMoist® for Presbyopic Contact Lens Wearers NCT02965820	Alcon, a Novartis Company	N/A
Completed	CLEAR CARE® PLUS for Presbyopic Contact Lens Wearers NCT02965833	Alcon, a Novartis Company	N/A
Completed	Safety, Tolerability and Efficacy of PresbiDrops (CSF-1) in Presbyopic Subjects NCT02965664	Orasis Pharmaceuticals Ltd.	Phase 2
Completed	Non-comparative Study to Assess the Visual Performances and Safety of a Progressive Multifocal Intraocular Len NCT02838004	SIFI SpA	N/A
Terminated	Clinical Investigation iDesign System With 1.3-PRESBY Treatment and STAR S4 IR™ Excimer Laser System NCT02806726	Abbott Medical Optics	N/A
Completed	Safety, Tolerability, and Efficacy of PresbiDrops (CSF-1), a Topical Ophthalmic Drug for Presbyopia NCT02745223	Orasis Pharmaceuticals Ltd.	Phase 2
Unknown	A New Successful Approach for Emmetropic Presbyopic Patients Using Intrastromal Pocket With Smile Module NCT05115058	Eye Hospital Pristina Kosovo	N/A
Completed	A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia NCT02780115	Allergan	Phase 2
Completed	A Study of the Concurrent Use of AGN-190584 and AGN-199201 in Participants With Presbyopia NCT02595528	Allergan	Phase 2
Completed	The Light Sword Lens for Presbyopia Compensation NCT03716271	Military Institute od Medicine National Research Institute	N/A
Completed	A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses NCT02719353	CooperVision, Inc.	N/A
Completed	A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses NCT02719366	CooperVision, Inc.	N/A
Completed	Presbyopic Phakic Intraocular Lens for Myopia Correction NCT03836898	Gemini Eye Clinic	N/A
Completed	Clinical Efficacy of the Pinhole Soft Contact Lenses for Correcting Presbyopia NCT02612584	Yonsei University	N/A
Unknown	A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near and Intermediate Vision in Pseudophak NCT02668523	ReVision Optics, Inc.	Phase 3
Completed	Changes of Angle Kappa After Implantation of Multifocal Intraocular Lenses NCT03297086	Semmelweis University	N/A
Completed	Dispensing Study to Assess the Visual Performance of Optimised Prototype Contact Lenses NCT02484586	Brien Holden Vision	N/A
Completed	A Study to Evaluate the Safety and Efficacy of EV06 Ophthalmic Solution in Improving Vision in Subjects With P NCT02516306	Encore Vision, Inc.	Phase 1 / Phase 2
Completed	Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia NCT02554396	LENZ Therapeutics, Inc	Phase 2
Completed	Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens NCT02487160	Lenstec Incorporated	Phase 3
Completed	Clinical Trial With PRECIZON Presbyopic NCT02409771	Ophtec BV	N/A
Completed	DAILIES® AquaComfort Plus® Multifocal (MF) - Comparative Assessment of Visual Performance NCT02403180	Alcon Research	N/A
Unknown	Mix and Match Study of Two Multifocal Intraocular Lens With Different Add Power NCT02556944	tae-young chung	N/A
Completed	Performance of a Multifocal Contact Lens - Presbyopia Study NCT02450747	Johnson & Johnson Vision Care, Inc.	N/A
Unknown	Functional Assessment of Activities of Daily Living (ADL) in Patients Who Underwent Mini-monovision Correction NCT02431156	Democritus University of Thrace	—
Completed	Presbyopia Compensation: Looking for Electrophysiological Predictors NCT02444130	University Hospital, Tours	—
Completed	Refraction Determination Analysis NCT01995435	Lee, Steven, M.D.	N/A
Completed	Presbyopia Screening by Community Health Worker in Bangladesh NCT03001258	Brac	—
Completed	Multifocal Lens Centration and Its Effect on Visual Performance in a Presbyopic Population NCT02228109	University of Waterloo	N/A
Unknown	A Prospective Safety and Effectiveness Study of a New High Repetition Rate Excimer Laser Using LASIK for the C NCT02112968	Technolas Perfect Vision GmbH	Phase 4
Completed	A Clinical Trial of The VisAbility Micro Insert System for Presbyopic Patients NCT02374671	Refocus Group, Inc.	N/A
Completed	Handling Comparison Between Two Contact Lens Types NCT02310126	Johnson & Johnson Vision Care, Inc.	N/A
Unknown	Development of a Validated Chart for Intermediate Vision Assessment NCT02279446	Democritus University of Thrace	—
Completed	Dispensing Study to Assess Visual Performance of Prototype Contact Lenses NCT02214797	Brien Holden Vision	N/A
Completed	DAILIES® AquaComfort Plus® Multifocal (MF) - Comparative Assessment of Visual Performance NCT02235831	Alcon Research	N/A
Completed	Driving Simulator Study Comparing Two Modes of Presbyopic Correction With Contact Lenses NCT02189863	Alcon Research	N/A
Completed	Evaluation of an Investigational Multifocal Lens NCT02223754	Johnson & Johnson Vision Care, Inc.	N/A
Unknown	A Prospective Safety and Effectiveness Study of the 500 Hz Technolas Perfect Vision Excimer Laser in Asian Eye NCT01977807	Technolas Perfect Vision GmbH	Phase 4
Completed	Retrospective / Prospective Clinical Study of AcrySof® IQ ReSTOR® +2.5 D Multifocal Toric Intraocular Lenses NCT02176343	Alcon Research	N/A
Completed	Multifocal Intraocular Lens x Monovision x Hybrid Monovision After Bilateral Cataract Surgery NCT02595177	Federal University of São Paulo	N/A
Completed	Safety and Efficacy of AGN-199201 and AGN-190584 in Patients With Presbyopia NCT02197806	Allergan	Phase 2
Completed	Visual Performance of Prototype Contact Lens Designs NCT02193555	Brien Holden Vision	N/A
Terminated	A Clinical Trial to Evaluate the Safety and Effectiveness of the Raindrop Near Vision Inlay for Pseudophakic S NCT03017612	ReVision Optics, Inc.	N/A
Unknown	Investigation of the Presbia Flexivue Microlens™ NCT02110472	PresbiBio, LLC	Phase 3
Completed	Multifocal High ADD Contact Lens Proof of Concept Trial NCT02117544	Alcon Research	N/A
Completed	LaserACE® Procedure Restore Visual Function and Range of Accommodation LaserACE® Procedure NCT01491360	ACE Vision Group, Inc.	N/A
Completed	Evaluation of a New Daily Disposable Multifocal Contact Lens Design NCT01951573	Alcon Research	N/A
Completed	A Study to Evaluate a Mid Add Multi-Focal Soft Contact Lens NCT01959178	Bausch & Lomb Incorporated	N/A
Completed	Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution NCT01809197	Alcon Research	N/A
Completed	Trial of the PresView Implant for the Improvement of Near Vision in Presbyopic Patients NCT01933750	Refocus Ocular Europe, B.V.	N/A
Completed	Clinical Evaluation of the Safety and Efficacy of a New Multifocal Contact Lens NCT01797783	Alcon Research	N/A
Completed	Evaluation of the Performance of Investigational Contact Lenses in a Presbyopic Population NCT01763047	Johnson & Johnson Vision Care, Inc.	N/A
Completed	Multifocal Lens Design Evaluation NCT01997216	Alcon Research	N/A
Unknown	Clinical Evaluation of a Progressive Addition Lens (PAL) NCT01443585	Ziv Hospital	N/A
Completed	Proclear 1-D Multifocal Nondispensing Study NCT01526902	CooperVision, Inc.	N/A
Completed	A Study to Evaluate the Feasibility of a High Add Multi Focal Contact Lens NCT01518868	Bausch & Lomb Incorporated	N/A
Completed	A Study to Evaluate the Product Performance of a Low Add MultiFocal Soft Contact Lens NCT01539694	Bausch & Lomb Incorporated	N/A
Completed	Clinical Evaluation of Biofinity Multifocal Compared With Air Optix Aqua Multifocal and With PureVision Multif NCT01591499	CooperVision, Inc.	N/A
Completed	Clinical Comparison of Two Multifocal Contact Lenses Made of Silicone Hydrogel Materials NCT01371539	CIBA VISION	N/A
Completed	Presbyopic Supracor Treatment for Near Myopic/Hyperopic Pseudophakic Eyes NCT01387360	Technolas Perfect Vision GmbH	Phase 4
Unknown	SUPRACOR for Myopia and Myopic Astigmatism NCT01404884	Technolas Perfect Vision GmbH	Phase 3
Completed	A Continuation Study To Monitor The Long Term Safety Of Patients Completing Protocols ACU-P08-020/020A NCT01895088	AcuFocus, Inc.	N/A
Completed	Safety and Effectiveness of the AcuFocus Corneal Inlay ACI7000PDT in Presbyopes NCT01352442	AcuFocus, Inc.	N/A
Completed	Prospective Study of Lens Performance of a Monthly Replacement Lens at Two Weeks and Four Weeks NCT01293240	CIBA VISION	N/A
Completed	Comparison of Two Multifocal Contact Lenses Worn on a Daily Disposable Basis NCT01254760	CIBA VISION	N/A
Completed	Clinical Assessment of a Multifocal Contact Lens for People Who Use Reading Glasses Only NCT01268501	CIBA VISION	N/A
Completed	Comparison of Two Multifocal Contact Lenses NCT01250054	CIBA VISION	N/A
Completed	Long Term Observation of Patient Satisfaction Post INTRACOR Treatment Based on Patient Perception and Diagnost NCT01164358	Technolas Perfect Vision GmbH	—
Completed	A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near Vision in Presbyopic Patients NCT01373580	ReVision Optics, Inc.	N/A
Completed	Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser P NCT01322919	Technolas Perfect Vision GmbH	Phase 3
Unknown	Visual and Economic Profits of ReSTOR® Multifocal Intraocular Lenses (IOL) on Public Health Patients in Spain NCT01088282	University of Barcelona	N/A
Withdrawn	Peripheral PresbyLASIK Using the Allegretto Wavelight System For The Treatment of Presbyopia NCT01059006	University of California, San Diego	N/A
Completed	Intrastromal Presbyopia Correction by Means of a Femtosecond Laser NCT01025050	Technolas Perfect Vision GmbH	Phase 3
Terminated	Feasibility Study of Laser Treatment of the Crystalline Lens to Correct Presbyopia NCT01062412	LensAR Incorporated	N/A
Completed	Clinical Evaluation of a Multifocal Contact Lens on Symptomatic Patients NCT01016652	Johnson & Johnson Vision Care, Inc.	N/A
Completed	Multifocal Contact Lens Use in Previous Contact Lens Wearers With Near Vision Demands NCT00965237	CIBA VISION	N/A
Completed	Multicenter Evaluation of Safety and Effectiveness of Presbyopic LASIK for Hyperopes NCT00910403	Technolas Perfect Vision GmbH	Phase 3
Completed	Clinical Evaluation of Two New Silicone Hydrogel Multifocal Products NCT00909792	CIBA VISION	N/A
Completed	Comparison of a Multifocal Contact Lens to a Traditional Multifocal Contact Lens NCT00886119	CIBA VISION	N/A
Completed	Clinical Assessment of a Customized Free-form Progressive Addition Lens Spectacle NCT01234207	University of California, Berkeley	N/A
Completed	Safety and Effectiveness Study of the AcuFocus Corneal Inlay ACI 7000PDT in Presbyopes NCT00850031	AcuFocus, Inc.	N/A
Completed	Comparison of Two New Silicone Hydrogel Multifocal Products NCT00823615	CIBA VISION	N/A
Completed	Safety and Effectiveness Study of the AcuFocus Corneal Inlay ACI 7000PDT in Presbyopes NCT00819299	AcuFocus, Inc.	N/A
Completed	Comparison of Three Soft Bifocal Contact Lenses NCT00808340	Johnson & Johnson Vision Care, Inc.	N/A
Completed	Comparison of Two Soft Bifocal Contact Lenses NCT00724945	Johnson & Johnson Vision Care, Inc.	N/A
Unknown	Intrastromal Correction of Ametropia by a Femtosecond Laser NCT00928122	20/10 Perfect Vision	Phase 3
Recruiting	Clinical Applications of Advanced Ophthalmic Imaging NCT03135327	University of Miami	N/A
Terminated	Randomized Clinical Trial of Bifocal Lenses Versus Computer-specific Progressive Addition Lenses NCT00585026	University of Alabama at Birmingham	Phase 3
Unknown	The Effect of Cataract Extraction on the Contractility of Ciliary Muscle NCT00624039	Samsung Medical Center	N/A
Completed	The VEPRO Trial: A Cross-Over Randomised Controlled Trial Comparing 2 Corrective Lenses for Patients With Pres NCT00635115	Santéclair	N/A
Withdrawn	Presbyopia in Breast Cancer Survivors NCT00271661	Alberta Health services	—
Completed	Trial of the PresVIEW Implant for the Improvement of Near Vision in Patients With Presbyopia NCT01166568	Refocus Group, Inc.	N/A