NCT00624039

The Effect of Cataract Extraction on the Contractility of Ciliary Muscle

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Samsung Medical Center · Academic / Other
• Sex: All
• Age: 55 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the changes in the pilocarpine-induced ciliary body movement before and after cataract extraction in order to determine the effect of lens sclerosis on the ciliary muscle contractility.

Detailed description

The functional changes in the ciliary body in presbyopia are not only important in a study of the mechanism for presbyopia but are also a key to various procedures or devices used to restore accommodation. Therefore, it is becoming increasingly important to quantify the in vivo accommodative changes in the aging ciliary muscle with and without a lens. We are going to evaluate the changes in the pilocarpine-induced contractility of the ciliary muscle in eyes with presbyopia before and after cataract extraction using ultrasound biomicroscopy (UBM).UBM will be performed with and without instilling 2 % pilocarpine, as well as before and 2 months after cataract extraction. Images of the ciliary body will be compared visually using Adobe Photoshop 7.0.

Conditions

• Presbyopia
• Cataract

Interventions

Type	Name	Description
OTHER	UBM with pilocarpine in presbyopia	ultrasound biomicroscopic examination in both eyes 30 minutes after one drop of 2% pilocarpine hydrochloride (Ocucarpine®, Samil Pharm., Seoul, Korea) instillation before and two months after cataract surgery

Timeline

• Start date: 2006-05-01
• Primary completion: 2008-03-01
• Completion: 2008-03-01
• First posted: 2008-02-26
• Last updated: 2008-02-26

Locations

1 site across 1 country: South Korea