NCT02554396

Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia

A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 (Aceclidine/Tropicamide) Ophthalmic Topical Formulation in the Treatment of Early to Moderate Presbyopia

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: LENZ Therapeutics, Inc · Academic / Other
• Sex: All
• Age: 45 Years – 59 Years
• Healthy volunteers: Not accepted

Summary

This is a one-day, randomized, double-masked, single-center evaluation of the efficacy and safety of PRX-100 ophthalmic solution compared to placebo in 20 subjects (randomized 4:1, PRX-100:placebo) to evaluate the safety of PRX-100 and the magnitude and duration of effects on improving near-vision acuity.

Conditions

• Presbyopia

Interventions

Type	Name	Description
DRUG	PRX-100	ophthalmic solution
DRUG	Placebo	saline ophthalmic solution

Timeline

• Start date: 2015-09-01
• Primary completion: 2015-11-01
• Completion: 2015-11-01
• First posted: 2015-09-18
• Last updated: 2017-10-23

Locations

1 site across 1 country: United States