Clinical Trials Directory

Trials / Completed

CompletedNCT03804268

Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia

A Phase 3, Multicenter, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Study Evaluating the Safety and Efficacy of AGN-190584 in Participants With Presbyopia

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
323 (actual)
Sponsor
Allergan · Industry
Sex
All
Age
40 Years – 55 Years
Healthy volunteers
Not accepted

Summary

A study to evaluate the efficacy, safety, and pharmacokinetics of pilocarpine hydrochloride (HCl) ophthalmic solution (AGN-190584) when administered bilaterally, once daily for 30 days in participants with presbyopia.

Conditions

Interventions

TypeNameDescription
OTHERVehicleVehicle, one drop in each eye, once daily, for up to 30 days.
DRUGPilocarpine HCl Ophthalmic SolutionPilocarpine HCl ophthalmic solution 1.25%, one drop in each eye, once daily, for up to 30 days.

Timeline

Start date
2018-12-21
Primary completion
2019-10-31
Completion
2019-10-31
First posted
2019-01-15
Last updated
2021-12-28
Results posted
2021-12-28

Locations

36 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03804268. Inclusion in this directory is not an endorsement.