NCT05001243

Comparison of a Compound With Pilocarpine and Brimonidine to Improve Near Vision in Healthy Presbyopic Patients

Comparison of Pilocarpine, Brimonidine, Oxymetazoline, Hialuronic Acid, Bromfenac Ophthalmic Compound With Pilocarpine and Brimonidine to Improve Uncorrected Visual Acuity in Healthy Presbyopic Individuals

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 11 (estimated)
• Sponsor: Optall Vision · Academic / Other
• Sex: All
• Age: 40 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Safety and Efficacy of Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac (PBOHB) ophthalmic compound compared to Pilocarpine and Brimonidine to improve uncorrected near vision in healthy presbyopic patients one hour after instillation.

Detailed description

To determine the safety and efficacy of a novel pharmacological compound of Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac (PBOHB) to improve uncorrected near vision in healthy presbyopic patients compared to Pilocarpine and Brimonidine one hour after binocular instillation.

Conditions

• Presbyopia

Interventions

Type	Name	Description
DRUG	Compound Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac	PBOHB to improve uncorrected near vision in healthy presbyopic patients
DRUG	Pilocarpine Hydrochloride	Apply in the fellow eye
DRUG	Brimonidine Tartrate	Apply in the fellow eye

Timeline

• Start date: 2021-08-10
• Primary completion: 2021-08-30
• Completion: 2021-09-10
• First posted: 2021-08-11
• Last updated: 2021-08-19

Locations

1 site across 1 country: Mexico