| Not Yet Recruiting | Pharmacokinetics of CFTR Modulators in Pregnant Individuals and in Postpartum Breastfeeding Mothers NCT04940533 | University of Minnesota | — |
| Not Yet Recruiting | Novel Point-of-care Sweat Chloride Testing Device for Monitoring CFTR Function NCT07414810 | Emory University | N/A |
| Not Yet Recruiting | Tele-Rehabilitation in Adults With Cystic Fibrosis NCT07500493 | King Saud University | N/A |
| Not Yet Recruiting | Effects of High-Frequency Chest Wall Oscillation Combined With Concurrent Training on Cough,in Cystic Fibrosis NCT07519460 | Riphah International University | N/A |
| Not Yet Recruiting | Safety and Efficacy of Inhaled BMD003 (CFTR mRNA) in Chinese Cystic Fibrosis Patients Aged ≥12 Years NCT07485543 | Peking Union Medical College Hospital | EARLY_Phase 1 |
| Recruiting | Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-272 in Healthy Participants NCT07437105 | Vertex Pharmaceuticals Incorporated | Phase 1 |
| Completed | Effect of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) on the PK of Rosuvastatin in Healthy Participan NCT07349394 | Vertex Pharmaceuticals Incorporated | Phase 1 |
| Recruiting | Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-581 in Healthy Participants NCT07283770 | Vertex Pharmaceuticals Incorporated | Phase 1 |
| Recruiting | Study of the Prevalence of Active/Passive Smoking and Vaping Among Patients With Cystic Fibrosis NCT07342920 | University Hospital, Strasbourg, France | — |
| Recruiting | A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine NCT07274631 | CHU de Reims | — |
| Not Yet Recruiting | Comparative Effects of Mechanical and Manual Airway Clearance Techniques in Cystic Fibrosis NCT07062939 | Riphah International University | N/A |
| Withdrawn | Rifaximin for Treatment of Bloating in Children and Adults With Cystic Fibrosis NCT05408910 | Wake Forest University Health Sciences | Phase 2 / Phase 3 |
| Recruiting | Assessing Tenapanor as a Treatment of CF-related Constipation. NCT06810167 | Massachusetts General Hospital | Phase 3 |
| Active Not Recruiting | A Long-term Study to Monitor the Health Status of People With Cystic Fibrosis Who Took Part in a Previous Stud NCT06962852 | Boehringer Ingelheim | Phase 1 / Phase 2 |
| Recruiting | Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL) NCT06683092 | Boston Children's Hospital | — |
| Recruiting | Oral Health Status of Cystic Fibrosis Patients. An Online Survey in Collaboration With the Vaincre la Mucovisc NCT06356246 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | A Phase 1 Study to Evaluate the Relative Bioavailability of a VX-828 Tablet Formulation NCT06861413 | Vertex Pharmaceuticals Incorporated | Phase 1 |
| Completed | Muscle Endurance in Children With Cystic Fibrosis NCT06812793 | Bezmialem Vakif University | — |
| Recruiting | Remote Sputum Collection in Cystic Fibrosis NCT06950892 | University of Pennsylvania | — |
| Recruiting | Continuous Glucose Monitoring and OGTT Screen for Cystic Fibrosis Related Diabetes in Cystic Fibrosis NCT06560463 | Medical College of Wisconsin | — |
| Recruiting | Evaluation of New Device for Beta-adrenergic Sweat Test in the Context of Stratification of Patient With Cysti NCT06836453 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Recruiting | Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis NCT06747858 | Arcturus Therapeutics, Inc. | Phase 2 |
| Recruiting | Streamlined Treatment of Pulmonary Exacerbations in Pediatrics NCT06654752 | University of Washington, the Collaborative Health Studies Coordinating Center | N/A |
| Recruiting | Impact of a Coordinated Dietetic-adapted Physical Activity Program on the Percentage of Lean Body Mass in Adul NCT06457451 | University Hospital, Tours | N/A |
| Active Not Recruiting | Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis Participants 12 Months of Age an NCT06460506 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Terminated | A Study to Test How Well BI 3720931 is Tolerated and Whether it Improves Lung Function in People With Cystic F NCT06515002 | Boehringer Ingelheim | Phase 1 / Phase 2 |
| Recruiting | Development of Non-Invasive Prenatal Diagnosis for Single Gene Disorders NCT06147414 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | A Study to Investigate the Safety and Tolerability of Single and Multiple Ascending Doses of KIT2014 in Health NCT06659757 | Kither Biotech Srl | Phase 1 |
| Recruiting | e-Health Program to Prevent Exacerbations in the Cystic Fibrosis Population NCT06313827 | University of Valencia | N/A |
| Completed | Performances and Safety of MuCopilot, a Digital Tool for the Unsupervised Objective Assessment of Cystic Fibro NCT06147778 | Ad scientiam | N/A |
| Recruiting | A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators NCT06504589 | Nicole Hamblett | — |
| Recruiting | Physical Activity Profile and Sedentary Behaviour in Adults With Cystic Fibrosis NCT06507956 | Hospices Civils de Lyon | — |
| Recruiting | A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF) NCT06526923 | Spirovant Sciences, Inc. | Phase 1 / Phase 2 |
| Recruiting | Establishment of a Primary Epididymal Cell Model From Epididymal Samples to Study CFTR Gene Regulation NCT06045702 | University Hospital, Brest | — |
| Recruiting | Acoustic Waveform Respiratory Evaluation NCT06512064 | Indiana University | N/A |
| Terminated | Frequency-time Analysis of Pathological Lung Sounds: Detection and Quantification of Pathological Sounds in Pa NCT06399094 | Groupe Hospitalier de la Region de Mulhouse et Sud Alsace | — |
| Completed | Natural History Study of Exocrine Pancreatic Function in Infants With Cystic Fibrosis (CF) NCT06506773 | Vertex Pharmaceuticals Incorporated | — |
| Recruiting | A Usability Validation of the MuCopilot Mobile Application, a Digital Tool for the Unsupervised Objective Asse NCT06132048 | Ad scientiam | N/A |
| Not Yet Recruiting | Maralixibat in Patients With Cystic Fibrosis and Constipation, A Within-Subjects Pilot Study NCT06413368 | Children's Hospital Los Angeles | Phase 2 / Phase 3 |
| Recruiting | Skin-interfaced Colorimetric Bifluidic Sweat Sensor Device for the Diagnosis of Cystic Fibrosis (CF) NCT05998629 | Milton S. Hershey Medical Center | N/A |
| Completed | A Two-Part Study to Evaluate the Efficacy, Safety, Tolerability and Pharmacokinetics of Repeat Doses of Inhale NCT06478706 | Enterprise Therapeutics Ltd | Phase 2 |
| Recruiting | Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients with Cystic Fibrosis NCT06429176 | SpliSense Ltd. | Phase 2 |
| Completed | A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis NCT06159725 | Clarametyx Biosciences, Inc. | Phase 1 / Phase 2 |
| Recruiting | FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases NCT06539169 | xCures | — |
| Recruiting | Targeting Inflammation With Losartan to Improve Response to Modulator Therapy in Cystic Fibrosis. NCT06364176 | University of Kansas Medical Center | Phase 2 |
| Completed | Clinical Trial to Evaluate the Efficacy and Safety of Dirocaftor/Posenacaftor/Nesolicaftor in Adults With CF NCT06468527 | Kors van der Ent | Phase 2 |
| Completed | Intrapulmonary Percussive Ventilation for Sputum Induction in Adults With Cystic Fibrosis NCT06311292 | Daniel J. Weiner | N/A |
| Recruiting | Health Outcomes of Parents With Cystic Fibrosis-Aim 2 NCT06296394 | University of Pittsburgh | — |
| Recruiting | Circadian Rhythm Disorders in Children With Cystic Fibrosis Under CFTR (Cystic Fibrosis Transmembrane Conducta NCT06370962 | Hospices Civils de Lyon | — |
| Active Not Recruiting | YOGA-CF (Yoga Outcomes Get Assessed in Cystic Fibrosis) NCT06120465 | Royal Brompton & Harefield NHS Foundation Trust | N/A |
| Completed | Effect of One Year Elexacaftor-tezacaftor-ivacaftor Treatment NCT06331000 | University Hospital, Strasbourg, France | — |
| Completed | A Study to Test How Well BI 1291583 is Tolerated by People With Cystic Fibrosis Bronchiectasis (Clairafly™) NCT05865886 | Boehringer Ingelheim | Phase 2 |
| Completed | A Study to Evaluate the Relative Bioavailability and Food Effect of a VX-118 Tablet Formulation NCT06312787 | Vertex Pharmaceuticals Incorporated | Phase 1 |
| Completed | An Intervention-Based Approach to Strengthen the Psychological Health of Children With Cystic Fibrosis and The NCT06280066 | Kirsehir Ahi Evran Universitesi | N/A |
| Recruiting | Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis NCT06216704 | Massachusetts General Hospital | — |
| Recruiting | French Validation of the AdT-Physio Scale NCT06273566 | Pole Sante Grace de Dieu | — |
| Recruiting | Improving the Well-being of Caregivers of Cystic Fibrosis Patients During Physiotherapy Treatment NCT06327802 | Pole Sante Grace de Dieu | — |
| Completed | A Study of Vanzacaftor/Tezacaftor/Deutivacaftor (VNZ/TEZ/D-IVA) in Healthy Adult Panelists NCT06299696 | Vertex Pharmaceuticals Incorporated | Phase 1 |
| Recruiting | A Pilot and Feasibility Study to Evaluate High vs Low Glycemic Index Mixed Meal Tolerance Test in Adolescents NCT06350149 | Emory University | N/A |
| Recruiting | CFTR Modulators in Pregnancy and Postpartum NCT06302270 | Region Stockholm | — |
| Completed | A Study To Evaluate the Relative Bioavailability, Food Effect, and Dose Proportionality of a Granule Formulati NCT06299709 | Vertex Pharmaceuticals Incorporated | Phase 1 |
| Recruiting | Pathogenicity of Species of the Achromobacter Genus in Patients From Reunion Island With Cystic Fibrosis NCT06371261 | Centre Hospitalier Universitaire de la Réunion | — |
| Unknown | Exercise in People With Cystic Fibrosis on CFTR Modulator Therapy NCT06322446 | Universidad Politecnica de Madrid | N/A |
| Completed | Development,Validity and Reliability of a Caregiver Version of the Breathlessness Beliefs Questionnaire NCT06289972 | Halic University | — |
| Recruiting | Muscle Function and Physical Activity in the Modern Era of Cystic Fibrosis NCT06251622 | Hospices Civils de Lyon | — |
| Completed | Effect of Parental Attitude on Functional and Physical Level of Children With Cystic Fibrosis NCT06306508 | Halic University | — |
| Enrolling By Invitation | Mycobacteriophage Treatment of Non-tuberculosis Mycobacteria NCT06262282 | National Jewish Health | — |
| Recruiting | A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Parti NCT06237335 | ReCode Therapeutics | Phase 2 |
| Active Not Recruiting | SGLT2 Inhibitor Therapy in Cystic Fibrosis-related Diabetes NCT06149793 | University of Minnesota | Phase 2 / Phase 3 |
| Recruiting | Regional Monitoring of CF Lung Disease NCT06339593 | Children's Hospital Medical Center, Cincinnati | EARLY_Phase 1 |
| Completed | Development a Core Set for Adults With Cystic Fibrosis Based on the ICF NCT06128499 | Hacettepe University | — |
| Recruiting | Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis NCT06154447 | Vertex Pharmaceuticals Incorporated | Phase 1 |
| Recruiting | Impact of Highly Effective Modulator Therapy on the Cystic Fibrosis Microbiome NCT05982795 | Dartmouth-Hitchcock Medical Center | — |
| Unknown | Dynamic Chest X-ray With Simultaneous Spirometry NCT06122051 | Liverpool Heart and Chest Hospital NHS Foundation Trust | — |
| Completed | Semaglutide in CFRD NCT05788965 | University of Minnesota | Phase 2 / Phase 3 |
| Not Yet Recruiting | ENHANCE- Establishing Natural History in an Advanced New CF Care Era NCT05986045 | Royal College of Surgeons, Ireland | — |
| Unknown | Multispectral Optoacoustic Tomography in Patients With Cystic Fibrosis NCT06063785 | University of Erlangen-Nürnberg Medical School | — |
| Unknown | Ceftolozane/Tazobactam Continuous Infusion for Infective Exacerbations of Cystic Fibrosis and Bronchiectasis NCT06035055 | Sunshine Coast Hospital and Health Service | Phase 4 |
| Recruiting | Lung Transplant READY CF 2: CARING CF Ancillary RCT NCT06032273 | University of Washington | N/A |
| Active Not Recruiting | Lung Transplant READY CF 2: A Multi-site RCT NCT06030206 | University of Washington | N/A |
| Completed | The Development and Evaluation of iCF-PWR for Healthy Siblings of Individuals With Cystic Fibrosis NCT06012084 | University of Regina | N/A |
| Unknown | The Effect of Bone Mineral Density in Patients With Adult Cystic Fibrosis NCT06088485 | Hacettepe University | — |
| Terminated | Symptom Based Performance of Airway Clearance After Starting Highly Effective Modulators for Cystic Fibrosis ( NCT05392855 | University of Missouri-Columbia | N/A |
| Recruiting | The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Rel NCT05723445 | Rhode Island Hospital | N/A |
| Recruiting | CF Organization of Care in the Era of Highly Effective Modulator. NCT06599892 | Hospices Civils de Lyon | — |
| Not Yet Recruiting | Peer-supporting for Teenagers With Cystic Fibrosis in the Transition of Care From Paediatric to Adult Services NCT05795673 | Hospices Civils de Lyon | N/A |
| Unknown | Relationship Between Health Literacy and Physical Activity in Adult Patients With Cystic Fibrosis NCT05963503 | Hacettepe University | — |
| Enrolling By Invitation | Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Partici NCT05844449 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Unknown | Evolution of the 6-minute Walk Test in Patients Treated With ELEXACAFTOR / TEZACAFTOR / IVACAFTOR NCT06184763 | Hospices Civils de Lyon | — |
| Unknown | Cystic Fibrosis and Periodontal Diseases NCT06133335 | CHU de Reims | N/A |
| Completed | Alternate Measures of Glucose During OGTT Testing for CFRD NCT05568134 | Children's Hospital of Philadelphia | — |
| Completed | Health Outcomes of Parents With Cystic Fibrosis NCT05829694 | University of Pittsburgh | — |
| Completed | ANNE Sensor Monitoring in Cystic Fibrosis NCT05941832 | Papworth Hospital NHS Foundation Trust | — |
| Recruiting | A Study Assessing KB407 for the Treatment of Cystic Fibrosis NCT05504837 | Krystal Biotech, Inc. | Phase 1 |
| Recruiting | FEED-Cystic Fibrosis (FEED-CF) NCT05766774 | Emory University | N/A |
| Unknown | The Living With a Long-Term Condition Study NCT06072287 | King's College London | — |
| Completed | Evaluation of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis (CF) Participants 12 to Less T NCT05882357 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Unknown | Understanding Gut Symptoms in People With Cystic Fibrosis NCT05934656 | University of Nottingham | — |
| Completed | Effects of Telerehabilitation-based Exercises in Cystic Fibrosis NCT05590169 | Istanbul Bilgi University | N/A |
| Unknown | Evaluating Bronchodilator Response in Patients With Bronchiectasis NCT05932316 | Rambam Health Care Campus | N/A |
| Recruiting | Estrogen Supplementation and Bone Health in Women With CF NCT05704036 | Johns Hopkins University | Phase 4 |
| Completed | Reproducibility of Virtual Exercise Assessments Versus Face-to-face Exercise Testing in Adults With Cystic Fib NCT06565832 | Royal Brompton & Harefield NHS Foundation Trust | N/A |
| Completed | An Electrocardiogram Study to Evaluate the Effect of Vanzacaftor on the QT/QTc Interval in Healthy Participant NCT05867147 | Vertex Pharmaceuticals Incorporated | Phase 1 |
| Recruiting | Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study NCT05548283 | Chris Goss | Phase 4 |
| Active Not Recruiting | Strength and Muscle Related Outcomes for Nutrition and Lung Function in CF NCT05639556 | Jaeb Center for Health Research | — |
| Recruiting | Sinus Disease in Young Children With Cystic Fibrosis NCT06191640 | University of California, Los Angeles | — |
| Active Not Recruiting | A Study of the Clinical Benefit of Tobramycin Inhalation Solution NCT06106789 | Qianfoshan Hospital | — |
| Terminated | Neuromodulation for Children With Cystic Fibrosis Experiencing Chronic Abdominal Pain NCT05515250 | St. Louis University | N/A |
| Recruiting | Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis NCT06163482 | University of Cincinnati | EARLY_Phase 1 |
| Completed | Inhaled Mannitol on Mucociliary Clearance in Moderate to Severe Cystic Fibrosis NCT05740618 | University of North Carolina, Chapel Hill | Phase 4 |
| Recruiting | Study to Assess Amphotericin B Cystetic for Inhalation (ABCI) Doses in Healthy Volunteers & People with Cystic NCT05802264 | Cystetic Medicines, Inc. | Phase 1 |
| Unknown | Sweat Response, Sweat Composition and Thermoregulatory Response to Exercise in Heat in Adults With Cystic Fibr NCT05896488 | University of Portsmouth | — |
| Completed | Evaluation of the Evolution of Quality of Life in Relation to Naso-sinus Symptomatology Under Treatment With C NCT05581056 | Hospices Civils de Lyon | — |
| Unknown | Effectiveness of CFTR Modulators According to Co-therapy NCT05663255 | Hospices Civils de Lyon | — |
| Recruiting | A Phase 1/2 Study of VX-522 in Participants With Cystic Fibrosis (CF) NCT05668741 | Vertex Pharmaceuticals Incorporated | Phase 1 / Phase 2 |
| Completed | Safety, Tolerability, and Pharmacokinetics of ARCT-032 in Healthy Adult Subjects and Adults With Cystic Fibros NCT05712538 | Arcturus Therapeutics, Inc. | Phase 1 |
| Withdrawn | Study to Determine the Efficacy&Safety of ARV-1801(ACG-701) for the Treatment of Cystic Fibrosis Pulmonary Exa NCT05641298 | Aceragen | Phase 2 |
| Unknown | Simultaneous quanTification of Elexacaftor/tezAcaftor/Ivacaftor Via Reverse Phase High Performance liquiD chro NCT05822102 | National Jewish Health | — |
| Unknown | Volatilomic Approaches for the Study of CFTR Modulators (VOLATIL-CF) NCT05726994 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Safety, Tolerability, and Pharmacokinetics of SPL84 in Healthy Volunteers NCT06217952 | SpliSense Ltd. | Phase 1 |
| Unknown | Pilot Trial of ExACT (Exercise as Airway Clearance Therapy) for People With Cystic Fibrosis NCT05482048 | University Hospital Southampton NHS Foundation Trust | N/A |
| Completed | Study to Assess an Enteric Microgranule Formulation of Adrulipase in Patients With Cystic Fibrosis NCT05719311 | Entero Therapeutics | Phase 2 |
| Enrolling By Invitation | Breath Analysis and Arterial Stiffness in Patients With Respiratory Diseases NCT05727852 | I.M. Sechenov First Moscow State Medical University | — |
| Unknown | Functional Tests to Resolve Unsolved Rare Diseases. Rares. NCT05696912 | University Hospital, Bordeaux | N/A |
| Completed | COVID-19 ANtibody Responses in Cystic Fibrosis: CAR-CF NCT05745948 | Hospital Universitari Vall d'Hebron Research Institute | — |
| Unknown | Fitness, Body Composition, Physical Activity and Sleep Patterns in People With Cystic Fibrosis on Modulator Th NCT05857709 | University of Portsmouth | — |
| Terminated | Imipenem/Cilastatin/Relebactam Pharmacokinetics, Safety, and Outcomes in Adults and Adolescents With Cystic Fi NCT05561764 | Hartford Hospital | Phase 4 |
| Unknown | Combating Diagnostic Wandering and Impasse for Cystic Fibrosis NCT05654480 | Societe Francaise de la Mucoviscidose | — |
| Unknown | Use of A-STEP Test in Cystic Fibrosis Patients NCT05809492 | Marmara University | N/A |
| Active Not Recruiting | Cardiac Structure and Function in Patients with Cystic Fibrosis NCT06084468 | Herlev and Gentofte Hospital | — |
| Unknown | The Relationship Between Diet and Glycemic Response and Inflammatory Markers in Children With Cystic Fibrosis NCT05748444 | büşra başpınar | — |
| Enrolling By Invitation | Prospective Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria NCT05686837 | University of North Carolina, Chapel Hill | — |
| Completed | Assessment of Cognitive Function and Exercise Capacity in Cystic Fibrosis NCT06175182 | Hacettepe University | — |
| Completed | Observational Study Comparing Home to Office Spirometry NCT05285410 | Chris Goss | — |
| Active Not Recruiting | Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Wit NCT05331183 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Active Not Recruiting | A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy NCT05444257 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Completed | Effectiveness of Respiratory Physiotherapy on Frequency of Exacerbations, Lung Function and Quality of Life Af NCT07088614 | University of Americas | N/A |
| Completed | Clinical and Genetic Profile of Pediatric Patients With Cystic Fibrosis in Sohag. NCT05599958 | Sohag University | — |
| Completed | A Phase 1b/2 Trial of the Safety and Microbiological Activity of Bacteriophage Therapy in Cystic Fibrosis Subj NCT05453578 | National Institute of Allergy and Infectious Diseases (NIAID) | Phase 1 / Phase 2 |
| Active Not Recruiting | Determinants of Daily Physical Activity Level in Patients With Cystic Fibrosis - Pilot Study Protocol NCT05206097 | University Hospital, Limoges | N/A |
| Completed | A Study to Evaluate the Relative Bioavailability of a Fixed-dose Combination Tablet of VX-121/Tezacaftor/Deuti NCT05535959 | Vertex Pharmaceuticals Incorporated | Phase 1 |
| Active Not Recruiting | Colorectal Cancer Screening in Cystic Fibrosis NCT05362344 | University of Washington, the Collaborative Health Studies Coordinating Center | — |
| Completed | Baby Detect : Genomic Newborn Screening NCT05687474 | Centre Hospitalier Universitaire de Liege | — |
| Unknown | Real-world Efficacy and Safety of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Modulator Therapy NCT05526027 | Universitair Ziekenhuis Brussel | N/A |
| Unknown | Daily Monitoring of Respiratory Symptoms and Spirometry During ETI Treatment in Persons With Cystic Fibrosis. NCT05599230 | CHC Montlegia | — |
| Unknown | COVID-19 Antibody Responses in Cystic Fibrosis NCT05561868 | Children's Health Ireland | — |
| Recruiting | COVID-19 Antibody Responses In Cystic Fibrosis NCT06274840 | Pilar Azevedo | — |
| Withdrawn | The Relationship Between CFTR Gene Mutations and Exercise Capacity NCT05157646 | Virginia Commonwealth University | N/A |
| Completed | Real-Time Assessment of Lung Structure and Function in Children and Young Adults With CF Using Electrical Impe NCT05455671 | University of Colorado, Denver | — |
| Completed | Pilot Study to Evaluate a Voice Journaling Application in Adolescents With Cystic Fibrosis NCT05420844 | University of Colorado, Denver | N/A |
| Completed | Inhaled Therapy Adherence and Outcomes to Kaftrio in Cystic Fibrosis NCT05519020 | Sheffield Teaching Hospitals NHS Foundation Trust | — |
| Completed | Pharmacokinetics and Safety Assessment of VX-121/Tezacaftor/Deutivacaftor in Participants With Moderate Hepati NCT05437120 | Vertex Pharmaceuticals Incorporated | Phase 1 |
| Completed | Video Telehealth Exercise Training in Cystic Fibrosis NCT04680403 | University of Alabama at Birmingham | N/A |
| Completed | Efficacy of Intensive Cholecalciferol Monitoring and Supplementation on Serum vitD Levels in Pediatric Patient NCT05276960 | Hospital Infantil de Mexico Federico Gomez | Phase 4 |
| Recruiting | Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age NCT05422222 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Completed | Nebulized Bacteriophage Therapy in Cystic Fibrosis Patients With Chronic Pseudomonas Aeruginosa Pulmonary Infe NCT05010577 | BiomX, Inc. | Phase 1 / Phase 2 |
| Completed | COVID-19 Antibody Responses in Cystic Fibrosis NCT05614336 | Hospices Civils de Lyon | N/A |
| Completed | Cefiderocol Pharmacokinetics in Adult Patients With Cystic Fibrosis NCT05314764 | Hartford Hospital | Phase 4 |
| Completed | Evaluation of Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) in Cystic Fibrosis Subject NCT05274269 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Recruiting | BEGIN Novel ImagiNG Biomarkers NCT05517655 | Children's Hospital Medical Center, Cincinnati | Phase 4 |
| Completed | Cystic Fibrosis and Frailtyh What's in Common? NCT06020547 | Federico II University | — |
| Completed | Investigation of Relationship Between Vascular Functions, Exercise Capacity, and Respiratory Functions in CF NCT04259983 | Hacettepe University | — |
| Unknown | Role of Toilet Bronchoscopy in RICU NCT04798118 | Assiut University | N/A |
| Unknown | Remote Monitoring of High-Risk Patients With Chronic Cardiopulmonary Diseases NCT04825067 | Institute of Bioengineering and Bioimaging (IBB) | N/A |
| Unknown | Gut Imaging for Function and Transit in Cystic Fibrosis 3 Junior NCT05699148 | Nottingham University Hospitals NHS Trust | — |
| Unknown | Study of Satisfaction of Patients and Care Providers for an Alternate Follow-up With In-hospital Consults and NCT05249322 | Hospices Civils de Lyon | N/A |
| Terminated | Validation of Therapeutic Efficacy Targeting the Splicing Variants in Cystic Fibrosis and CFTR Pathologies NCT05100823 | University Hospital, Montpellier | N/A |
| Completed | TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era NCT05752019 | Erasmus Medical Center | — |
| Recruiting | Patienthèque of Finisterian (South of Brittany) Children With Cystic Fibrosis in the Time of Precision Medicin NCT04137133 | University Hospital, Brest | N/A |
| Completed | Feasibility of Home-based Exercise Program for Adults With Cystic Fibrosis NCT05239611 | University of Kansas Medical Center | Phase 2 |
| Unknown | Description of the Short-term Effects of KAFTRIO® by Continuous Monitoring With the PHEAL-CR-K Application in NCT05295524 | Hopital Foch | N/A |
| Withdrawn | A Study of Inhaled KB407 for the Treatment of Cystic Fibrosis NCT05095246 | Krystal Biotech, Inc. | Phase 1 |
| Completed | Pilot Study of a CF-specific CBT Intervention for Adolescents NCT05271643 | Massachusetts General Hospital | N/A |
| Completed | Study to Assess the Safety and PK of Oral and IV Xenleta in Adults With Cystic Fibrosis NCT05225805 | Nabriva Therapeutics AG | Phase 1 |
| Completed | A Comprehensive Approach To Relief Of Digestive Symptoms In Cystic Fibrosis: CARDS-CF NCT05251467 | Nottingham University Hospitals NHS Trust | — |
| Unknown | Trikafta/Kaftrio and Pseudomonas Aeruginosa NCT05675592 | Ospedale San Raffaele | — |
| Active Not Recruiting | Effect of Losartan in Cystic Fibrosis (CF)-NIH Grant #133240 NCT03435939 | University of Kansas Medical Center | EARLY_Phase 1 |
| Active Not Recruiting | COVID-19 Antibody Responses In Cystic Fibrosis NCT05074680 | Insel Gruppe AG, University Hospital Bern | — |
| Recruiting | Metformin for People With CFRD on CFTR Modulator Therapy to Improve Ion Channel Function NCT04530383 | University of Kansas Medical Center | Phase 2 |
| Unknown | COVID-19 Antibody Responses in Cystic Fibrosis (CAR-CF) NCT05217784 | Rabin Medical Center | — |
| Completed | Pilocarpine Microneedles for Sweat Induction (PMN-SI) NCT04732195 | Emory University | N/A |
| Completed | Perceptions of the CF Screening Protocol Incorporating NGS NCT06299566 | King's College London | — |
| Completed | Evaluation of Long-term Safety and Efficacy of ELX/TEZ/IVA in Cystic Fibrosis (CF) Participants 2 Years and Ol NCT05153317 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Completed | A Study Evaluating the Safety of Elexacaftor/Tezacaftor/Ivacaftor in Participants With Cystic Fibrosis (CF) NCT05111145 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Active Not Recruiting | Airway Microbiome of Cystic Fibrosis Patients NCT06057558 | University Hospital, Antwerp | N/A |
| Unknown | Renal Impact of KAFTRIO in Mucoviscidose Population NCT06197490 | Hospices Civils de Lyon | — |
| Active Not Recruiting | PEP and O-PEP Device for Nebulization in Cystic Fibrosis NCT06964074 | National Institute for Tuberculosis and Lung Diseases, Poland | N/A |
| Unknown | COVID-19 Antibody Responses In Cystic Fibrosis NCT05158829 | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | — |
| Withdrawn | Thermic Effect of Feeding in Cystic Fibrosis NCT03931252 | Virginia Commonwealth University | N/A |
| Unknown | Performance and Patient Acceptance of a Commercially Available Beverage as Compared to an Oral Glucose Solutio NCT05377502 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | — |
| Completed | Lung Transplant READY Pilot Study NCT05135156 | University of Washington | N/A |
| Completed | A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Brensocatib Tablets in Adults With Cystic NCT05090904 | Insmed Incorporated | Phase 2 |
| Recruiting | Identification of Dysglycemia With Continuous Glucose Monitoring to Assess Clinical Evolution in Cystic Fibros NCT05099939 | Institut de Recherches Cliniques de Montreal | — |
| Completed | Psychosocial Factors and Quality of Life in the Effect of Fear of COVID-19 With Cystic Fibrosis NCT05195216 | Elif Kabasakal | — |
| Unknown | COVID-19 Antibody Responses In Cystic Fibrosis NCT04863573 | Queen's University, Belfast | — |
| Recruiting | Trikafta Exercise Study in Cystic Fibrosis NCT05279040 | University of British Columbia | — |
| Recruiting | Canadian Observational Study Evaluating the Long-term IMPACT of Cystic Fibrosis Transmembrane Conductance Regu NCT05200429 | University of British Columbia | — |
| Completed | Ketone Supplementation in Cystic Fibrosis NCT04938726 | University of Alabama at Birmingham | N/A |
| Terminated | Study of a Nebulised Nitric Oxide Generating Solution in Patients With Mycobacterium Abscessus NCT05101915 | Papworth Hospital NHS Foundation Trust | Phase 2 |
| Completed | A Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Who Are Homozygous for F508del NCT05076149 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Recruiting | Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Init NCT05635266 | Sanguine Biosciences | — |
| Completed | Remotely Supervised Exercise for Adults With Cystic Fibrosis NCT05173194 | Universidad Europea de Madrid | N/A |
| Completed | A Pilot Study of a Low Glycemic Load Diet in Adults With Cystic Fibrosis NCT04519853 | Boston Children's Hospital | N/A |
| Completed | NETwork of Linoleic Acid Supplementation in Cystic Fibrosis NCT04531410 | Karolinska Institutet | N/A |
| Completed | Treatment With Elexacaftor/Tezacaftor/Ivacaftor, in Patients With Cystic Fibrosis and Caloric Intake NCT06072365 | University Hospital, Toulouse | — |
| Enrolling By Invitation | Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs NCT04930289 | Paragonix Technologies | — |
| Completed | Effects of Training Intensity on Physical Fitness and Body Composition in Cystic Fibrosis NCT05140967 | University of Kiel | N/A |
| Completed | Study to Evaluate Symptoms of Exocrine Pancreatic Insufficiency in Adult Participants With Cystic Fibrosis or NCT05069597 | AbbVie | Phase 4 |
| Completed | The Use of Breath Volatile Organic Compounds in Early Detection of Acute Pulmonary Exacerbations in Cystic Fib NCT05944367 | Papworth Hospital NHS Foundation Trust | — |
| Completed | A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Participants With Cystic Fibrosis (CF) NCT04969224 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Completed | CFTR Modulators and Gastrointestinal Complications NCT05253859 | Nottingham University Hospitals NHS Trust | — |
| Active Not Recruiting | Prospective Study of Pregnancy in Women With Cystic Fibrosis NCT04828382 | Amalia Magaret | — |
| Completed | A Phase 3 Study of VX-121 Combination Therapy in Participants With Cystic Fibrosis (CF) Heterozygous for F508d NCT05033080 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Unknown | Intestine-lung Axis of Cystic Fibrosis Patients Treated With the Combination Elexacaftor/Tezacaftor/Ivacaftor NCT05937815 | University Hospital, Bordeaux | N/A |
| Active Not Recruiting | COVID-19 Antibody Responses in Cystic Fibrosis NCT05052294 | University Hospital, Motol | — |
| Terminated | Bright Light Therapy for Depression Symptoms in Adults With Cystic Fibrosis (CF) and COPD NCT04921332 | Erica Osborn | N/A |
| Recruiting | Markers of Osteoporosis in Cystic Fibrosis NCT03921060 | University of Texas Southwestern Medical Center | Phase 4 |
| Completed | Safety and Feasibility of High-intensity Interval Training Program in CF Patients NCT04888767 | Fondation Ildys | N/A |
| Terminated | Cystic Fibrosis and Urinary Incontinence NCT04922255 | Megan Bradley | N/A |
| Withdrawn | A Dose-finding Study of Inhaled OligoG vs Placebo in Patients With Cystic Fibrosis NCT03698448 | AlgiPharma AS | Phase 2 / Phase 3 |
| Completed | COVID-19 Antibody Responses In Cystic Fibrosis: CAR-CF NCT05054582 | Medical University Innsbruck | — |
| Unknown | Training in Shared Decision-making of Cystic Fibrosis Centers Competences in the Treatment of CF Related Diabe NCT04891159 | Hospices Civils de Lyon | — |
| Completed | COVID-19 Antibody Responses in Cystic Fibrosis NCT04992234 | Vastra Gotaland Region | — |
| Completed | Magnetic Resonance Imaging and Neuro-Psychological Testing In Cystic Fibrosis NCT04451213 | Cardiff and Vale University Health Board | N/A |
| Completed | Comparison Between Ultra-low-dose Computed Tomography and Lung MRI in Cystic Fibrosis NCT04644471 | Assistance Publique - Hôpitaux de Paris | N/A |
| Terminated | Cell Content of Sputum Induced by Hypertonic Saline in Adolescents With Cystic Fibrosis NCT06909903 | Assistance Publique Hopitaux De Marseille | N/A |
| Recruiting | GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance NCT04731272 | University of Pennsylvania | Phase 2 |
| Unknown | Ovarian Reserve in Women With Cystic Fibrosis and the Correlation With Demographic and Clinical Parameters NCT05029817 | Hadassah Medical Organization | — |
| Completed | Clinical Effort Against Smoke Exposure in Cystic Fibrosis NCT04777344 | University of Alabama at Birmingham | N/A |
| Completed | Cystic Fibrosis Blood Neutrophils NCT04970225 | Assistance Publique - Hôpitaux de Paris | N/A |
| Completed | MyVoice:CF Decision Aid for Women With Cystic Fibrosis NCT04825236 | University of Pittsburgh | N/A |
| Completed | Pharmacokinetics of Omadacycline in Cystic Fibrosis NCT04460586 | Paul Beringer | Phase 4 |
| Completed | Integrating Electronic Patient Reported Biometric Measures (ePReBMs) From Wearable Devices in Respiratory Dise NCT04857814 | University of Alberta | N/A |
| Completed | A Decentralized Study to Evaluate Physical Activity and Cough Frequency Using Wearable Technology in Cystic Fi NCT04923464 | Vertex Pharmaceuticals Incorporated | — |
| Completed | Pragmatic Implementation Trial of a CF Primary Palliative Care Intervention NCT04923880 | Massachusetts General Hospital | N/A |
| Active Not Recruiting | The PROMISE Pediatric Study 6 to 11 Years Old NCT04613128 | Nicole Hamblett | — |
| Completed | A First in Human Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Single and Multiple Ascend NCT04926701 | Enterprise Therapeutics Ltd | Phase 1 |
| Unknown | Monocytes as Predictors of Cystic Fibrosis-related Bone Disease NCT04877223 | Université de Reims Champagne-Ardenne | — |
| Completed | MENstrual Symptom Tracking to Understand and Assess (Women) Living With Cystic Fibrosis NCT04620096 | University of Washington | — |
| Unknown | General Health, Attitudes, and Activity in Self-directed Exercise in Patients With Cystic Fibrosis (GAINS-CF) NCT04882267 | University of Virginia | N/A |
| Unknown | Covid-19 Antibody Responses in Cystic Fibrosis NCT05012306 | Universitätsklinikum Köln | — |
| Completed | HERO-2: Home-Reported Outcomes With CFTR Modulator Therapy NCT04798014 | Indiana University | — |
| Completed | COVID-19 Antibody Responses In Cystic Fibrosis NCT04904445 | Erasmus Medical Center | — |
| Completed | Case-control Study of Sleep Disorders in Children With Cystic Fibrosis NCT04847882 | University Hospital, Strasbourg, France | — |
| Terminated | Airway Clearance for Pediatric and Adult Cystic Fibrosis Patients Using a Portable Intra-Pulmonary Percussion NCT04743206 | University of Florida | N/A |
| Unknown | Use of Capnography for the Follow-up of Cystic Fibrosis Children NCT04814797 | Central Hospital, Nancy, France | — |
| Recruiting | Testing Drug Efficacy in Cystic Fibrosis Through N-of-1 Trials NCT04580368 | Children's Hospital Medical Center, Cincinnati | N/A |
| Completed | Acceptability, Feasibility and Preliminary Efficacy of CFWP to Treat Clinically Elevated Fatigue in Adults Wit NCT04809207 | Johns Hopkins University | N/A |
| Completed | Bacille Calmette-Guerin (BCG) Vaccine for Immune Protection Against Infections NCT04884308 | Johns Hopkins University | Phase 2 |
| Unknown | A New Posaconazole Dosing Regimen for Paediatric Patients With Cystic Fibrosis and Aspergillus Infection NCT04966234 | Bambino Gesù Hospital and Research Institute | Phase 2 / Phase 3 |
| Completed | The Impact Of A Tele-Exercise Program For Children With Cystic Fibrosis During The Covid-19 Pandemic On Qualit NCT05481190 | Ondokuz Mayıs University | N/A |
| Completed | An Assistive Powered Wheelchair: Stage 2 Trial NCT05292690 | East Kent Hospitals University NHS Foundation Trust | — |
| Completed | CYstic Fibrosis bacterioPHage Study at Yale (CYPHY) NCT04684641 | Yale University | Phase 1 / Phase 2 |
| Completed | Upper Extremity Exercise Capacity, Muscle Oxygenation, Balance in Patients With Cystic Fibrosis NCT04803643 | Gazi University | — |
| Completed | Oral Glucose Tolerance Testing Using Candy for Cystic Fibrosis NCT04579939 | Mayo Clinic | N/A |
| Completed | Concerns of Children Whose Parents Have Cystic Fibrosis NCT04702386 | Assistance Publique - Hôpitaux de Paris | — |
| Completed | Immune Profiles in CF Fungal Infection NCT04476758 | University of Alabama at Birmingham | — |
| Recruiting | Regional Phenotyping of CF and Non-CF Bronchiectasis NCT04793867 | Children's Hospital Medical Center, Cincinnati | — |
| Withdrawn | CFTR Related Pancreatitis Study NCT04274413 | The Hospital for Sick Children | N/A |
| Recruiting | Quantitation and Spatial Registration of Airways Dysfunction With Dynamic 19F MRI in Cystic Fibrosis NCT06057714 | University of North Carolina, Chapel Hill | — |
| Completed | Efficacy of an Infrared Visualization Technique for the Identification of the Peripheral Venous Access Site in NCT04226118 | Hospices Civils de Lyon | N/A |
| Unknown | Improving Therapeutic Adherence With a Co-constructed Program Involving Both Patients and Health Care Professi NCT03226795 | Hospices Civils de Lyon | N/A |
| Completed | A Study to Assess the Effect of ELX/TEZ/IVA on Glucose Tolerance in Participants With Cystic Fibrosis (CF) NCT04599465 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Completed | The Impact of Patch Rx Technologies on Adherence to Vitamin and Trikafta Therapies in Patients With Cystic Fib NCT04684823 | The University of Texas Health Science Center at San Antonio | N/A |
| Completed | Feasibility of a Goal-based Agenda Setting Intervention NCT04696484 | Dartmouth-Hitchcock Medical Center | N/A |
| Completed | A Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis (C NCT04545515 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Completed | SELF-BREATHE RCT for Chronic Breathlessness NCT04574050 | King's College Hospital NHS Trust | N/A |
| Completed | Physical Activity, Exercise Capacity and Coronavirus Phobia of Adult Cystic Fibrosis Patients During COVID-19 NCT04673331 | Hacettepe University | — |
| Withdrawn | Medication Adherence and Non-adherence in Adults With Rare Disease NCT04541875 | Xperiome | — |
| Unknown | Effects of a Telerehabilitation Approach in Children With Cystic Fibrosis NCT04683809 | Marmara University | N/A |
| Unknown | Characterization of Pulmonary Microbiome in Cystic Fibrosis Patients NCT04735679 | University Hospital, Montpellier | — |
| Unknown | Effect of the CFTR-modulating Triple Therapy Elexacaftor - Tezacaftor - Ivacaftor NCT05576324 | University of Erlangen-Nürnberg Medical School | — |
| Completed | The Effects of Telerehabilitation on Muscle Function, Physical Activity and Sleep in Cystic Fibrosis During Pa NCT04742049 | Hacettepe University | N/A |
| Completed | Qualitative Understanding of Experiences With the SIMPLIFY Trial NCT04320381 | Boston Children's Hospital | — |
| Completed | Ph 1/2 Study Evaluating Safety and Tolerability of Inhaled AP-PA02 in Subjects With Chronic Pseudomonas Aerugi NCT04596319 | Armata Pharmaceuticals, Inc. | Phase 1 / Phase 2 |
| Completed | Evaluation of Lung T1-MRI in Pediatric Cystic Fibrosis Patients NCT04994301 | University Hospitals Cleveland Medical Center | — |
| Enrolling By Invitation | Prospective Analysis of Urine LAM to Eliminate NTM Sputum Screening NCT04579211 | Jerry A. Nick, M.D. | — |
| Completed | A Pilot Study to Assess the Effect of Intermittent iNO on the Treatment of NTM Lung Infection in CF and Non-CF NCT04685720 | Beyond Air Inc. | N/A |
| Withdrawn | Epidemiology and Treatment of Small-colony Variant Staphylococcus Aureus in Cystic Fibrosis NCT02547116 | Johns Hopkins University | Phase 4 |
| Withdrawn | Human MesenchymAl Stem Cells Infusion in Patients With Cystic Fibrosis NCT03058068 | Joshua M Hare | Phase 1 |
| Completed | Feasibility of a New Model for Exercise Prescription in Cystic Fibrosis NCT04075864 | University of Alabama at Birmingham | N/A |
| Completed | Evaluation of ELX/TEZ/IVA in Cystic Fibrosis (CF) Subjects 2 Through 5 Years NCT04537793 | Vertex Pharmaceuticals Incorporated | Phase 3 |
| Recruiting | Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Ch NCT04509050 | Sonya Heltshe | — |
| Active Not Recruiting | Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic Fibrosis NCT04467957 | Children's Hospital Medical Center, Cincinnati | Phase 4 |
| Recruiting | Exercise in Child Health NCT05359991 | University of California, Irvine | N/A |
| Completed | Streamlined Treatment of Pulmonary Exacerbations in Pediatrics Pilot Study NCT04608019 | University of Washington, the Collaborative Health Studies Coordinating Center | N/A |
| Terminated | Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders NCT02748798 | Thunder Bay Regional Health Research Institute | EARLY_Phase 1 |
| Recruiting | Hyperpolarized 129Xe MR Imaging of Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease NCT04624490 | Mario Castro, MD, MPH | Phase 1 |
| Completed | The Effect of Telerehabilitation on Functional Capacity, Oxidative Stress and Respiratory Parameters in Cystic NCT05147285 | Hacettepe University | N/A |
| Completed | Gut Imaging for Function & Transit in CF - GIFT-CF 3 NCT04618185 | Nottingham University Hospitals NHS Trust | — |
| Completed | Proximal Intestinal Obstruction Syndrome (PIOS) in a Patient With Cystic Fibrosis: A New Syndrome NCT04613063 | Tecnologico de Monterrey | — |
| Completed | Manual Chest Physiotherapy and Active Cycle of Breathing Techniques (ACBT) in Patients of Cystic Fibrosis NCT05026918 | Riphah International University | N/A |
| Active Not Recruiting | Microbial Biomarkers of EArly Pseudomonas Aeruginosa Colonization in CHildren With Cystic Fibrosis NCT03947957 | University Hospital, Brest | N/A |
| Completed | Assessment of Contraceptive Safety and Effectiveness in Cystic Fibrosis NCT04568980 | University of Washington | — |
| Active Not Recruiting | Real World Clinical Outcomes With Novel Modulator Therapy Combinations in People With CF (RECOVER) NCT04602468 | Royal College of Surgeons, Ireland | Phase 4 |
| Unknown | Cystic Fibrosis Remote Monitoring System NCT04453358 | Koronis Biomedical Technologies | N/A |
| Completed | Impact of Discontinuing Hypertonic Saline in People With CF on Highly Effective CFTR Modulators- A SIMPLIFY Su NCT06350461 | Nicole Hamblett | N/A |
| Completed | Impact of Discontinuing Dornase Alfa in People With CF on Highly Effective CFTR Modulator Therapy-A SIMPLIFY S NCT06350474 | Nicole Hamblett | N/A |
| Completed | Impact of Discontinuing Chronic Therapies in People With Cystic Fibrosis on Highly Effective CFTR Modulator Th NCT04378153 | Nicole Hamblett | — |
| Withdrawn | Vitamin K Supplementation to Reduce Deficiencies in Adults With Cystic Fibrosis NCT04496921 | Institut de Recherches Cliniques de Montreal | N/A |