NCT04798118

Role of Toilet Bronchoscopy in RICU

A Study on Toilet Bronchoscopy In Respiratory ICU, Assiut University Hospital

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 130 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Toilet bronchoscopy is a potentially therapeutic intervention to aspirate retained secretions within the endotracheal tube and airways and revert atelectasis. Aspiration of airway secretions is the most common indication to perform a therapeutic bronchoscopy in the intensive care unit (ICU) . Toilet bronchoscopy is particularly beneficial when retained secretions are visible during the procedure and when air-bronchograms are not present at the chest radiograph. It is also beneficial when there is an indication to reverse lobar atelectasis, rather than simply to remove accumulated mucus. Toilet bronchoscopy is used in lobar and complete lung collapse in mechanically ventilated patients who fail to respond to treatments such as physiotherapy or recruitment manoeuvres. The success rates (defined as radiographic improvement on chest X-ray \[CXR\] or an improved PaO2/PAO2 ratio) in the ICU patient population had. Patients with acute hypoxaemic respiratory failure may already be on non-invasive ventilation (NIV), or require NIV preemptively for Fiberoptic Bronchoscopy (FB). These patients should be considered high risk for requiring intubation post-procedure; therefore, Fiberoptic Bronchoscopy should be performed by an experienced operator in a setting allowing facilities to safely secure the airways. NIV with early therapeutic FB rather than mechanical ventilation can help avoid intubation and reduce tracheostomy rate. Hospital mortality, duration of ventilation, and hospital stay remain similar

Detailed description

Aim Of Work To study the value of toilet bronchoscopy in 1. Mechanical ventilated patients with chest disease and copious secretion. 2. Mechanical ventilated patients diagnosed to have atelectasis radiologically. 3. Patients on non-invasive ventilation with chest diseases and copious secretion 4. Compare Different types of mucolytics during toilet bronchoscopy in mechanically ventilated patients. 5. Compare Different types of sedations during toilet bronchoscopy in mechanically ventilated patients.

Conditions

• COPD
• Asthma
• Cystic Fibrosis

Interventions

Type	Name	Description
PROCEDURE	toilet bronchoscope	Toilet bronchoscopy will be done by infuse normal saline or N-Acetylcysteine with a syringe, observing the flow of saline at the distal tip of the bronchoscope then suction intra bronchial visible secretions during the procedure and also suction of specific lobe guided by radiological finding in the patient A chest X-ray will be routinely performed prior and after the procedure, HRCT is mandatory when chest x-ray not clearly defining the collapse monitoring of heart rate, oxygen saturation, ventilator parameters, and arterial blood pressure will be done

Timeline

• Start date: 2022-04-01
• Primary completion: 2023-10-01
• Completion: 2023-12-01
• First posted: 2021-03-15
• Last updated: 2023-08-15

Locations

1 site across 1 country: Egypt