| Not Yet Recruiting | Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188 | National Institute of Neurological Disorders and Stroke (NINDS) | Phase 1 / Phase 2 |
| Not Yet Recruiting | Study of MT027 in Patients with Brain, Meninges, and Spinal Cord Metastatic Solid Tumors NCT06742593 | Suzhou Maximum Bio-tech Co., Ltd. | Phase 1 |
| Terminated | AXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing Surgery NCT03965494 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | EARLY_Phase 1 |
| Completed | Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midli NCT03696355 | St. Jude Children's Research Hospital | Phase 1 |
| Completed | A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or R NCT03150862 | BeiGene USA, Inc. | Phase 1 / Phase 2 |
| Withdrawn | BBBD Followed By Methotrexate and Carboplatin With or Without Trastuzumab in Treating Women With Breast Cancer NCT00397501 | OHSU Knight Cancer Institute | Phase 1 / Phase 2 |
| Completed | Mibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma NCT01480050 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 |
| Completed | Studying Gene Expression and Location in Samples From Patients With Brain Tumors NCT01585389 | Children's Oncology Group | — |
| Completed | Studying Gene Expression in Samples From Patients With Rhabdoid Tumors NCT01553175 | Children's Oncology Group | — |
| Completed | Bortezomib, Temozolomide, and Regional Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastom NCT00998010 | Jonsson Comprehensive Cancer Center | Phase 2 |
| Completed | Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor NCT01381718 | University of South Florida | Phase 2 |
| Completed | Olaparib and Temozolomide in Treating Patients With Relapsed Glioblastoma NCT01390571 | Cancer Research UK | Phase 1 |
| Completed | Gene Mutation in Samples From Young Patients With Pleuropulmonary Blastoma Syndrome at Risk for Developing Can NCT01353300 | Children's Oncology Group | — |
| Completed | Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma NCT01273090 | Children's Oncology Group | Phase 1 |
| Completed | Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multifo NCT01062399 | Radiation Therapy Oncology Group | Phase 1 / Phase 2 |
| Completed | PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors NCT01158300 | Pediatric Brain Tumor Consortium | Phase 1 |
| Unknown | High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Hav NCT01172912 | Fondazione IRCCS Istituto Nazionale dei Tumori, Milano | Phase 2 |
| Completed | Vaccine Therapy, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Mu NCT01222221 | Cancer Research UK | Phase 1 |
| Completed | Veliparib and Temozolomide in Treating Patients With Recurrent Glioblastoma NCT01026493 | Radiation Therapy Oncology Group | Phase 1 / Phase 2 |
| Withdrawn | Biomarkers in Blood Samples From Young Patients With Newly Diagnosed Brain Tumors Undergoing Standard Radiatio NCT01233479 | Pediatric Brain Tumor Consortium | N/A |
| Completed | Imaging Procedure Using ALA in Finding Residual Tumor in Grade IV Malignant Astrocytoma NCT00752323 | Andrew Sloan, MD | Phase 2 |
| Withdrawn | Temozolomide in Treating Patients With Invasive Pituitary Tumors NCT00601289 | Jonsson Comprehensive Cancer Center | Phase 2 |
| Active Not Recruiting | Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma NCT00978458 | Eastern Cooperative Oncology Group | Phase 3 |
| Terminated | Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft T NCT01204450 | UNC Lineberger Comprehensive Cancer Center | Phase 1 |
| Completed | Radiation Therapy and Temsirolimus or Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma NCT01019434 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 2 |
| Active Not Recruiting | Radiation Therapy With Concomitant and Adjuvant Temozolomide Versus Radiation Therapy With Adjuvant PCV Chemot NCT00887146 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Recruiting | 3'-Deoxy-3'-[18F] Fluorothymidine PET Imaging in Patients With Cancer NCT00935090 | Barbara Ann Karmanos Cancer Institute | — |
| Completed | Boron Neutron Capture Therapy, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed G NCT00974987 | Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan | Phase 2 |
| Completed | ABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme NCT00770471 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 |
| Completed | Bevacizumab and Erlotinib After Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed G NCT00720356 | Northwestern University | Phase 2 |
| Completed | HSPPC-96 Vaccine With Temozolomide in Patients With Newly Diagnosed GBM NCT00905060 | University of California, San Francisco | Phase 2 |
| Unknown | Hydroxyurea With or Without Imatinib Mesylate in Treating Patients With Recurrent or Progressive Meningioma NCT00904735 | Istituto Scientifico H. San Raffaele | Phase 2 |
| Completed | Dasatinib or Placebo, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblasto NCT00869401 | Alliance for Clinical Trials in Oncology | Phase 1 / Phase 2 |
| Completed | Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma NCT00895622 | Radiation Therapy Oncology Group | Phase 2 |
| Completed | Presurgery Bortezomib for Recurrent Malignant Gliomas Followed by Postop Bortezomib & Temozolomide NCT00990652 | Northwestern University | Phase 2 |
| Terminated | Nelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma Multiforme NCT00915694 | Abramson Cancer Center at Penn Medicine | Phase 1 |
| Terminated | Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer NCT00726830 | M.D. Anderson Cancer Center | N/A |
| Completed | Everolimus, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma NCT00553150 | Alliance for Clinical Trials in Oncology | Phase 1 / Phase 2 |
| Completed | Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer NCT00823524 | Asan Medical Center | Phase 1 / Phase 2 |
| Completed | Cilengitide and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Lung Cancer NCT00884598 | Universitätsmedizin Mannheim | Phase 1 |
| Withdrawn | Pilot Study of MGd + High-dose MTX-Based Chemoimmunotherapy + RT for Newly Dx PCNSL NCT00734773 | Northwestern University | EARLY_Phase 1 |
| Terminated | Influenza Vaccine in Preventing Flu in Patients Who Have Undergone Stem Cell Transplant and in Healthy Volunte NCT00952185 | City of Hope Medical Center | N/A |
| Withdrawn | Lymphokine-Activated Killer Cells or Gliadel Wafer in Treating Patients With Newly Diagnosed Glioblastoma Mult NCT00814593 | Lisata Therapeutics, Inc. | Phase 2 |
| Terminated | Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Mali NCT00788125 | City of Hope Medical Center | Phase 1 / Phase 2 |
| Completed | Bevacizumab and Sorafenib in Treating Patients With Recurrent Glioblastoma Multiforme NCT00621686 | Alliance for Clinical Trials in Oncology | Phase 2 |
| Unknown | Tumor Tissue, Blood Samples, and Family History in Predicting Tumor Development and Response to Treatment in Y NCT00891722 | Children's Cancer and Leukaemia Group | — |
| Completed | Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Cli NCT00890435 | Children's Oncology Group | — |
| Terminated | MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Gli NCT00756106 | Massachusetts General Hospital | N/A |
| Terminated | MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer NCT00572182 | Pediatric Brain Tumor Consortium | Phase 1 |
| Completed | A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of NCT00784914 | City of Hope Medical Center | Phase 1 |
| Withdrawn | Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers NCT00770419 | Rutgers, The State University of New Jersey | — |
| Completed | Radiation Therapy, Arsenic Trioxide, and Temozolomide in Treating Patients With Newly Diagnosed High-Grade Gli NCT00720564 | City of Hope Medical Center | Phase 1 |
| Unknown | Study of Cerebrospinal Fluid Samples in Diagnosing Carcinomatous Meningitis in Patients With Cancer or Meninge NCT00938756 | Centre Oscar Lambret | N/A |
| Completed | Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clin NCT00750009 | Case Comprehensive Cancer Center | Phase 3 |
| Active Not Recruiting | Observing Young Patients With Ependymoma Undergoing Standard Combination Chemotherapy NCT00683319 | Children's Cancer and Leukaemia Group | — |
| Unknown | Study of Genes and Environment in Patients With Cancer in East Anglia, Trent, or West Midlands Regions of the NCT00757614 | Cancer Research UK | — |
| Completed | Levetiracetam or Pregabalin in Treating Seizures in Patients Undergoing Chemotherapy and/or Radiation Therapy NCT00629889 | Dr Andrea Rossetti | Phase 2 |
| Unknown | Temozolomide and Radiation Therapy in Treating Young Patients With Pontine Glioma NCT00514397 | Children's Cancer and Leukaemia Group | Phase 2 |
| Terminated | Testosterone Gel in Preventing Weakness Caused by Steroid Therapy in Men With Glioma NCT00631137 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | N/A |
| Active Not Recruiting | Risk-Adapted Therapy for Young Children With Embryonal Brain Tumors, Choroid Plexus Carcinoma, High Grade Glio NCT00602667 | St. Jude Children's Research Hospital | Phase 2 |
| Unknown | Radiation Therapy in Treating Patients Who Have Undergone Surgery for Newly Diagnosed Grade II or Grade III Me NCT00626730 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 2 |
| Active Not Recruiting | Phase III Trial of Anaplastic Glioma Without 1p/19q Loss of Heterozygosity (LOH) NCT00626990 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 3 |
| Completed | Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Mu NCT00482677 | Canadian Cancer Trials Group | Phase 3 |
| Completed | Hydroxychloroquine, Radiation, and Temozolomide Treating Patients With Newly Diagnosed Glioblastoma Multiforme NCT00486603 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 / Phase 2 |
| Withdrawn | Vaccine Therapy and GM-CSF in Treating Patients With CNS Lymphoma NCT00621036 | University of Texas Southwestern Medical Center | Phase 2 |
| Terminated | Studying Fentanyl in Patients With Cancer NCT00899951 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | — |
| Unknown | CT-322 in Treating Patients With Recurrent Glioblastoma Multiforme and Combination Therapy With Irinotecan NCT00562419 | Adnexus, A Bristol-Myers Squibb R&D Company | Phase 2 |
| Terminated | Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma Multiforme NCT01233492 | Cancer Research UK | Phase 1 |
| Terminated | VNP40101M and Temozolomide in Treating Patients With Progressive or Relapsed Malignant Glioma NCT00516282 | Northwestern University | Phase 1 |
| Unknown | Enzastaurin and Temozolomide in Treating Patients With Primary Gliomas NCT00516607 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 1 |
| Unknown | Early Hospital Discharge or Standard Inpatient Care in Cancer Patients Receiving Antibiotics for Febrile Neutr NCT00445497 | Clatterbridge Centre for Oncology | Phase 3 |
| Completed | Cytochlor, Tetrahydrouridine, and External-Beam Radiation Therapy in Treating Patients With Cancer That Has Sp NCT00521183 | Brian Lally | Phase 1 |
| Completed | Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumors NCT00503724 | Pediatric Brain Tumor Consortium | Phase 1 |
| Completed | Temozolomide in Treating Patients With Recurrent Glioblastoma Multiforme or Other Malignant Glioma NCT00498927 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | Vandetanib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Diffuse Brainstem Glioma NCT00472017 | St. Jude Children's Research Hospital | Phase 1 |
| Completed | Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme NCT00387400 | NCIC Clinical Trials Group | Phase 1 |
| Completed | High-Dose Methotrexate in Treating Young Patients With Solid Tumors NCT00513981 | Children's Cancer and Leukaemia Group | Phase 1 |
| Completed | Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors NCT00470366 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Withdrawn | Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Re NCT00458744 | Children's Oncology Group | Phase 1 |
| Completed | Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed NCT00390403 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 |
| Withdrawn | Levetiracetam in Treating Patients With Seizures Caused by Brain Metastases NCT00415376 | Northwestern University | N/A |
| Completed | Tetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade Glioma NCT00404248 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 / Phase 2 |
| Completed | Pemetrexed Disodium in the Cerebrospinal Fluid of Patients With Leptomeningeal Metastases NCT00424242 | Northwestern University | EARLY_Phase 1 |
| Completed | Epothilone ZK-219477 in Treating Patients With Recurrent Glioblastoma NCT00424060 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 2 |
| Unknown | Radiation Therapy, Temozolomide, Tamoxifen, and Carboplatin in Treating Patients With Malignant Gliomas NCT00492687 | San Diego Pacific Oncology & Hematology Associates | Phase 2 |
| Terminated | O(6)-Benzylguanine and Temozolomide in Treating Patients With Glioblastoma Multiforme That Did Not Respond to NCT00436436 | National Cancer Institute (NCI) | Phase 2 |
| Terminated | Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Thera NCT00471653 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | — |
| Completed | Improving the Selection of Patients With Glioblastoma Multiforme for Treatment With Epidermal Growth Factor Re NCT00897663 | Alliance for Clinical Trials in Oncology | — |
| Unknown | Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastati NCT00551122 | University of Southampton | Phase 1 / Phase 2 |
| Completed | Tumor Tissue Analysis in Patients Receiving Imatinib Mesylate for Malignant Glioma NCT00401024 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 |
| Terminated | Rosiglitazone in Treating Patients With Pituitary Tumors NCT00616642 | Jonsson Comprehensive Cancer Center | Phase 2 |
| Completed | Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma NCT00509431 | Jonsson Comprehensive Cancer Center | Phase 1 |
| Completed | Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With NCT00423852 | Memorial Sloan Kettering Cancer Center | Phase 1 / Phase 2 |
| Withdrawn | Studying Cerebrospinal Fluid Proteins and Angiogenesis Proteins in Young Patients With Newly Diagnosed Central NCT00897858 | Pediatric Brain Tumor Consortium | — |
| Completed | Standard Radiation Therapy, Higher-Dose Radiation Therapy, or Chemotherapy in Treating Older Patients With Gli NCT00820963 | Centre Leon Berard | Phase 3 |
| Completed | Stress Reduction Program in Patients With Malignant Brain Tumors and Their Family Caregivers NCT00376818 | Case Comprehensive Cancer Center | N/A |
| Completed | Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to th NCT00452868 | Wake Forest University Health Sciences | EARLY_Phase 1 |
| Completed | Bevacizumab, Temozolomide, and External Beam Radiation Therapy as First-Line Therapy in Treating Patients With NCT01013285 | Jonsson Comprehensive Cancer Center | Phase 2 |
| Completed | Vinblastine and Carboplatin in Treating Young Patients With Newly Diagnosed or Recurrent Low-Grade Glioma NCT00352495 | Children's Oncology Group | Phase 1 |
| Completed | Vaccine Therapy in Treating Patients With Malignant Glioma NCT00612001 | Jonsson Comprehensive Cancer Center | Phase 1 |
| Completed | Vatalanib in Treating Patients With Recurrent or Progressive Meningioma NCT00348790 | Northwestern University | Phase 2 |
| Completed | ATN-161 and Carboplatin in Treating Patients With Recurrent Malignant Glioma NCT00352313 | National Institutes of Health Clinical Center (CC) | Phase 1 / Phase 2 |
| Completed | Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) With Bevacizumab and Irinotecan for Malignant G NCT00352521 | Duke University | Phase 2 |
| Withdrawn | Early Enteral Tube Feedings in Children Receiving Chemo for AML/MDS & High Risk Solid Tumors NCT00624962 | Vanderbilt University | N/A |
| Completed | Bevacizumab in Treating Patients With Recurrent or Progressive Glioma NCT00337207 | Northwestern University | Phase 2 |
| Completed | Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors NCT00313599 | University of California, San Francisco | Phase 1 |
| Terminated | Ph I Study of Lithium During Whole Brain Radiotherapy For Patients With Brain Metastases NCT00469937 | Vanderbilt-Ingram Cancer Center | Phase 1 |
| Completed | Positron Emission Tomography Using Fluorothymidine F 18 in Finding Recurrent Disease in Patients With Gliomas NCT00276770 | University of Washington | N/A |
| Completed | O6-Benzylguanine and Temozolomide in Treating Young Patients With Recurrent or Progressive Gliomas or Brain St NCT00275002 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Capecitabine and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Nonmetastatic Brain Stem G NCT00357253 | Pediatric Brain Tumor Consortium | Phase 1 |
| Completed | Radiation Therapy (RT) and Temozolomide (TMZ) in Treating Patients With Newly Diagnosed Glioblastoma or Gliosa NCT00304031 | Radiation Therapy Oncology Group | Phase 3 |
| Completed | Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients With Central Nervous System Cancer or Leptomeningeal NCT00445965 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | Temozolomide in Treating Patients With Primary Brain Tumors or Metastatic Brain Tumors NCT00547131 | City of Hope Medical Center | Phase 1 |
| Completed | Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Br NCT00303940 | National Institutes of Health Clinical Center (CC) | Phase 1 |
| Completed | GP96 Heat Shock Protein-Peptide Complex Vaccine in Treating Patients With Recurrent or Progressive Glioma NCT00293423 | University of California, San Francisco | Phase 1 / Phase 2 |
| Unknown | Pemetrexed Disodium in Treating Patients With Recurrent Malignant Gliomas, Primary CNS Lymphoma, or Brain Meta NCT00276783 | Northwestern University | Phase 2 |
| Completed | Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors NCT00138216 | Children's Oncology Group | Phase 1 |
| Withdrawn | Immunotoxin Therapy in Treating Children With Recurrent Malignant Gliomas NCT00053040 | Pediatric Brain Tumor Consortium | Phase 1 / Phase 2 |
| Completed | Iodine I 131 Monoclonal Antibody TNT-1/B in Treating Patients With Progressive or Recurrent Glioblastoma Multi NCT00128635 | Abramson Cancer Center at Penn Medicine | Phase 1 |
| Completed | Developing Interview Questions to Estimate Workplace Exposure to Electric and Magnetic Fields NCT00340054 | National Institutes of Health Clinical Center (CC) | — |
| Completed | Temozolomide Alone or in Combination With Thalidomide and/or Isotretinoin and/or Celecoxib in Treating Patient NCT00112502 | M.D. Anderson Cancer Center | Phase 2 |
| Terminated | Erlotinib in Treating Patients With Progressive Glioblastoma Multiforme NCT00227032 | UNC Lineberger Comprehensive Cancer Center | Phase 1 |
| Terminated | MT2004-30: Tomotherapy for Solid Tumors NCT00623077 | Masonic Cancer Center, University of Minnesota | Phase 1 |
| Completed | Combination Chemotherapy and Radiation Therapy in Treating Younger Patients Who Are Undergoing an Autologous S NCT00253487 | Children's Hospital Medical Center, Cincinnati | N/A |
| Terminated | Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors NCT00112619 | Pediatric Brain Tumor Consortium | Phase 1 |
| Completed | High-Dose Methotrexate and Leucovorin in Treating Patients With Newly Diagnosed Glioblastoma Multiforme NCT00082797 | Eastern Cooperative Oncology Group | Phase 2 |
| Completed | Imatinib Mesylate, Vatalanib, and Hydroxyurea in Treating Patients With Recurrent or Relapsed Malignant Glioma NCT00387933 | Duke University | Phase 1 |
| Completed | Radiation Therapy or Temozolomide in Treating Patients With Gliomas NCT00182819 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 3 |
| Unknown | Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer NCT00349024 | Children's Cancer and Leukaemia Group | N/A |
| Completed | Temozolomide and Radiation Therapy With or Without Vatalanib in Treating Patients With Newly Diagnosed Gliobla NCT00128700 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 1 / Phase 2 |
| Completed | Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain NCT00666211 | Vanderbilt-Ingram Cancer Center | Phase 3 |
| Unknown | Arsenic Trioxide, Temozolomide, and Radiation Therapy in Treating Patients With Malignant Glioma That Has Been NCT00275067 | Northwestern University | Phase 1 / Phase 2 |
| Completed | Acute Side Effects in Patients Who Are Undergoing Stereotactic Radiosurgery for Brain Tumors or Other Brain Di NCT00255671 | Case Comprehensive Cancer Center | — |
| Unknown | Erlotinib Alone or in Combination With Radiation Therapy in Treating Young Patients With Refractory or Relapse NCT00360854 | Children's Cancer and Leukaemia Group | Phase 1 |
| Completed | Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors NCT00107458 | Children's Oncology Group | Phase 1 |
| Completed | Bevacizumab and Irinotecan in Treating Patients With Recurrent or Refractory Gliomas NCT00268359 | Duke University | Phase 2 |
| Completed | Risk Factors for Developing a Blood Clot in Patients Who Are Undergoing Cancer Treatment for Newly Diagnosed G NCT00253669 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | — |
| Completed | Metabolic Syndrome in Childhood Cancer Survivors NCT00920738 | University of Minnesota | — |
| Completed | Erlotinib and Radiation Therapy in Treating Young Patients With Newly Diagnosed Glioma NCT00124657 | St. Jude Children's Research Hospital | Phase 1 / Phase 2 |
| Completed | High Light and Low Light Dose PDT in Glioma NCT00118222 | Case Comprehensive Cancer Center | Phase 3 |
| Unknown | High-Dose Methotrexate in Treating Young Patients With Residual Ependymoma NCT00287924 | Children's Cancer and Leukaemia Group | Phase 2 |
| Terminated | Temozolomide During and After Radiation Therapy in Treating Patients Who Have Undergone Previous Surgery and P NCT00238277 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 2 |
| Completed | VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors NCT00098761 | Pediatric Brain Tumor Consortium | Phase 1 |
| Completed | Temozolomide and Radiation Therapy in Treating Patients With Gliomas NCT00114140 | Radiation Therapy Oncology Group | Phase 2 |
| Completed | Bortezomib and Temozolomide in Treating Patients With Brain Tumors or Other Solid Tumors That Have Not Respond NCT00544284 | City of Hope Medical Center | Phase 1 |
| Completed | Vaccine Therapy in Treating Young Patients Who Are Undergoing Surgery for Malignant Glioma NCT00107185 | Jonsson Comprehensive Cancer Center | Phase 1 |
| Terminated | Radiotherapy or Radiosurgery Compared With Observation Alone in Treating Patients With Newly Diagnosed, Benign NCT00104936 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 3 |
| Completed | Lapatinib in Treating Patients With Recurrent Glioblastoma Multiforme NCT00099060 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Terminated | Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant NCT00238173 | OHSU Knight Cancer Institute | Phase 1 |
| Terminated | Study of Stored Tumor Samples in Young Patients With Brain Tumors NCT00897286 | St. Jude Children's Research Hospital | — |
| Completed | Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multifo NCT00099125 | Radiation Therapy Oncology Group | Phase 2 |
| Completed | Arsenic Trioxide and Radiation Therapy in Treating Young Patients With Newly Diagnosed Gliomas NCT00095771 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 |
| Terminated | Dietary, Herbal and Alternative Medicine in Glioblastoma Multiforme NCT00243022 | Ali Altunkaya | Phase 2 |
| Completed | Changes in Semen or Sperm Caused by Temozolomide in Patients With Newly Diagnosed, Progressive, or Recurrent P NCT00499798 | Wake Forest University Health Sciences | — |
| Completed | Imatinib Mesylate and Temozolomide in Treating Patients With Malignant Glioma NCT00354068 | Duke University | Phase 1 |
| Completed | Study of Blood Samples and Risk of Infection in Patients With Newly Diagnosed Malignant Supratentorial Astrocy NCT00999622 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | — |
| Completed | Pharmacologic Study of Methotrexate in Patients Undergoing Stereotactic Biopsy for Recurrent High-Grade Glioma NCT00463008 | New Approaches to Brain Tumor Therapy Consortium | N/A |
| Terminated | TP-38 Toxin in Treating Young Patients With Recurrent or Progressive Supratentorial High-Grade Glioma NCT00074334 | Pediatric Brain Tumor Consortium | Phase 1 / Phase 2 |
| Completed | Erlotinib Compared With Temozolomide or Carmustine in Treating Patients With Recurrent Glioblastoma Multiforme NCT00086879 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 2 |
| Completed | Gimatecan in Treating Patients With Recurrent or Progressive Primary Malignant Glioma NCT00087061 | Jonsson Comprehensive Cancer Center | Phase 1 / Phase 2 |
| Unknown | Cisplatin and Temozolomide in Treating Young Patients With Malignant Glioma NCT00360945 | Children's Cancer and Leukaemia Group | Phase 2 |
| Completed | Everolimus and Gefitinib in Treating Patients With Progressive Glioblastoma Multiforme or Progressive Metastat NCT00085566 | Memorial Sloan Kettering Cancer Center | Phase 1 / Phase 2 |
| Completed | Alanosine in Treating Patients With Progressive or Recurrent Malignant Gliomas NCT00075894 | National Cancer Institute (NCI) | Phase 1 |
| Unknown | Combination Chemotherapy With or Without Etoposide Followed By an Autologous Stem Cell Transplant in Treating NCT00392886 | Children's Hospital Los Angeles | Phase 3 |
| Unknown | Lonafarnib and Temozolomide in Treating Patients With Recurrent Primary Supratentorial Gliomas NCT00083096 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 1 |
| Completed | Thalidomide, Celecoxib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Malignan NCT00047281 | Dana-Farber Cancer Institute | Phase 2 |
| Withdrawn | Collecting and Storing Blood Samples From Patients With Cancer NCT00900120 | University of Medicine and Dentistry of New Jersey | — |
| Terminated | Radiolabeled MAB Therapy in Patients With Refractory, Recurrent, or Advanced CNS or Leptomeningeal Cancer NCT00089245 | Y-mAbs Therapeutics | Phase 1 |
| Unknown | Radiation Therapy Followed By Combination Chemotherapy in Treating Young Patients With Supratentorial Primitiv NCT00274911 | Children's Cancer and Leukaemia Group | Phase 2 |
| Completed | Thalidomide and Procarbazine in Treating Patients With Recurrent or Progressive Malignant Glioma NCT00079092 | Wake Forest University Health Sciences | Phase 2 |
| Completed | Radiation Therapy Plus Thalidomide and Temozolomide in Treating Patients With Newly Diagnosed Brain Metastases NCT00049361 | Wake Forest University Health Sciences | Phase 2 |
| Completed | CC-8490 in Treating Patients With Recurrent or Refractory High-Grade Gliomas NCT00074243 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Magnetic Resonance Imaging and Magnetic Resonance Spectroscopic Imaging in Evaluating Patients Who Are Undergo NCT00274755 | University of California, San Francisco | Phase 2 |
| Completed | AEE788 and Everolimus in Treating Patients With Recurrent or Relapsed Glioblastoma Multiforme NCT00107237 | Novartis Pharmaceuticals | Phase 1 / Phase 2 |
| Completed | Surgery Followed by Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme NCT00053183 | National Cancer Institute (NCI) | Phase 1 |
| Terminated | Celecoxib in Patients With Newly Diagnosed GBM Who Are Receiving Anticonvulsant Drugs and Undergoing RT NCT00068770 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 2 |
| Unknown | Hyperbaric Oxygen Therapy in Treating Patients With Radiation Necrosis of the Brain NCT00087815 | Barrett Cancer Center | N/A |
| Unknown | Combination Chemotherapy and Radiation Therapy With or Without Methotrexate in Treating Young Patients With Ne NCT00278278 | German Society for Pediatric Oncology and Hematology GPOH gGmbH | Phase 3 |
| Completed | Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Primary CNS Lymphoma NCT00416819 | University of California, San Francisco | N/A |
| Completed | Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors NCT00070096 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | Treatment of Patients With Newly Diagnosed Medulloblastoma, Supratentorial Primitive Neuroectodermal Tumor, or NCT00085202 | St. Jude Children's Research Hospital | Phase 3 |
| Completed | Combination Chemotherapy, Monoclonal Antibody, and Radiation Therapy in Treating Patients With Primary Central NCT00068250 | Radiation Therapy Oncology Group | Phase 1 / Phase 2 |
| Completed | Talampanel in Treating Patients With Recurrent High-Grade Glioma NCT00064363 | National Institutes of Health Clinical Center (CC) | Phase 2 |
| Terminated | Bortezomib and Temozolomide in Treating Patients With Advanced Refractory Solid Tumors or Melanoma NCT00512798 | Vanderbilt-Ingram Cancer Center | Phase 1 / Phase 2 |
| Completed | Vaccine Therapy in Treating Patients With Malignant Glioma NCT00068510 | Jonsson Comprehensive Cancer Center | Phase 1 |
| Completed | Tamoxifen, Carboplatin, and Topotecan in Treating Patients With CNS Metastases or Recurrent Brain or Spinal Co NCT00541138 | City of Hope Medical Center | Phase 2 |
| Completed | Poly-ICLC in Treating Patients With Recurrent or Progressive Anaplastic Glioma NCT00058123 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 2 |
| Terminated | Carmustine Implants and O(6)-Benzylguanine in Treating Children With Recurrent Malignant Glioma NCT00045721 | Pediatric Brain Tumor Consortium | Phase 1 |
| Completed | Intrathecal Radioimmunotherapy, Radiation Therapy, and Chemotherapy After Surgery in Treating Patients With Me NCT00058370 | Memorial Sloan Kettering Cancer Center | N/A |
| Unknown | Radiation Therapy Plus Combination Chemotherapy in Treating Children With Medulloblastoma NCT00053872 | University of Leicester | Phase 3 |
| Terminated | Treating Patients With Recurrent PCNSL With Carboplatin/BBBD and Adding Rituxan To The Treatment Regimen NCT00074165 | OHSU Knight Cancer Institute | Phase 2 |
| Completed | Chemotherapy and Radiation Therapy After Surgery in Treating Children With Newly Diagnosed Astrocytoma, Gliobl NCT00028795 | Children's Oncology Group | Phase 2 |
| Completed | Stereotactic Radiosurgery and Radiation Therapy in Treating Patients With Glioblastoma Multiforme NCT00253448 | Case Comprehensive Cancer Center | Phase 2 |
| Completed | Irinotecan and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Solid Tumors NCT00389584 | University of California, Davis | Phase 1 / Phase 2 |
| Terminated | Biological Therapy and Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme NCT00052715 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 2 |
| Completed | Oxaliplatin in Treating Children With Recurrent or Refractory Medulloblastoma, Supratentorial Primitive Neuroe NCT00047177 | Pediatric Brain Tumor Consortium | Phase 2 |
| Completed | Brachytherapy in Treating Patients With Recurrent Malignant Glioma NCT00045474 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignan NCT00052455 | Institute of Cancer Research, United Kingdom | Phase 3 |
| Completed | Modafinil in Treating Fatigue and Behavioral Change in Patients With Primary Brain Cancer NCT00052286 | Jonsson Comprehensive Cancer Center | N/A |
| Unknown | Erlotinib in Treating Patients With Recurrent or Progressive Glioblastoma Multiforme NCT00054496 | The Cleveland Clinic | Phase 2 |
| Completed | Intrathecal Rituximab in Treating Patients With Recurrent CNS Lymphoma NCT00416923 | University of California, San Francisco | Phase 1 |
| Completed | Dalteparin and Radiation Therapy in Treating Patients With Newly Diagnosed Supratentorial Glioblastoma Multifo NCT00028678 | Eastern Cooperative Oncology Group | Phase 2 |
| Unknown | Immunotoxin Therapy in Treating Children With Progressive or Recurrent Glioblastoma Multiforme or Anaplastic A NCT00052624 | Xenova Biomedix | Phase 1 |
| Completed | Irinotecan Plus Radiation Therapy Followed By Chemotherapy in Treating Patients With Glioblastoma Multiforme NCT00027612 | Alliance for Clinical Trials in Oncology | Phase 1 / Phase 2 |
| Completed | Temozolomide Plus Radiation Therapy in Treating Patients With Newly Diagnosed Anaplastic Oligodendrogliomas or NCT00033280 | Radiation Therapy Oncology Group | Phase 2 |
| Completed | Sirolimus in Treating Patients With Glioblastoma Multiforme NCT00047073 | Jonsson Comprehensive Cancer Center | Phase 1 / Phase 2 |
| Completed | Atrasentan in Treating Patients With Progressive or Recurrent Malignant Glioma NCT00017264 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Boron Neutron Capture Therapy Following Surgery in Treating Patients With Glioblastoma Multiforme Removed Duri NCT00004015 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 1 |
| Unknown | Quality of Life in Patients Who Have Undergone Previous Treatment for Primitive Neuroectodermal Tumors NCT00278239 | Children's Cancer and Leukaemia Group | — |
| Completed | Proton Beam Radiation Therapy in Treating Young Patients Who Have Undergone Biopsy or Surgery for Medulloblast NCT00105560 | Massachusetts General Hospital | N/A |
| Completed | Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the NCT00039572 | Beth Israel Deaconess Medical Center | Phase 1 / Phase 2 |
| Completed | Gadolinium Texaphyrin Plus Radiation Therapy in Treating Patients With Supratentorial Glioblastoma Multiforme NCT00006452 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 |
| Completed | Motexafin Gadolinium in Treating Patients With Glioblastoma Multiforme Who Are Undergoing Radiation Therapy to NCT00032097 | National Cancer Institute (NCI) | Phase 1 |
| Terminated | Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors NCT00031798 | Wake Forest University Health Sciences | Phase 3 |
| Completed | ABT-751 in Treating Young Patients With Refractory Solid Tumors NCT00036959 | National Institutes of Health Clinical Center (CC) | Phase 1 |
| Completed | Thalidomide and Irinotecan in Treating Patients With Glioblastoma Multiforme Who Have Undergone Radiation Ther NCT00039468 | Dartmouth-Hitchcock Medical Center | Phase 2 |
| Completed | CC-5013 in Treating Patients With Recurrent Glioma NCT00036894 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer NCT00053118 | Roswell Park Cancer Institute | Phase 1 |
| Completed | Imatinib Mesylate in Treating Patients With Gliomas NCT00039364 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 2 |
| Completed | Cellular Adoptive Immunotherapy Using Genetically Modified T-Lymphocytes in Treating Patients With Recurrent o NCT00730613 | City of Hope Medical Center | Phase 1 |
| Completed | Gefitinib Plus Temozolomide in Treating Patients With Malignant Primary Glioma NCT00027625 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 |
| Completed | SarCNU in Treating Patients With Recurrent Malignant Glioma NCT00036660 | NCIC Clinical Trials Group | Phase 2 |
| Completed | Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors NCT00049023 | O'Dorisio, M S | Phase 1 |
| Completed | Karenitecin in Treating Patients With Recurrent Malignant Glioma NCT00014521 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Mafosfamide in Treating Patients With Progressive or Refractory Meningeal Tumors NCT00031928 | National Cancer Institute (NCI) | Phase 1 |
| Completed | SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors NCT00015899 | Pediatric Brain Tumor Consortium | Phase 1 |
| Unknown | Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Metastatic Medulloblastoma Who NCT00276666 | Children's Cancer and Leukaemia Group | Phase 2 |
| Completed | Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy NCT00030108 | National Institutes of Health Clinical Center (CC) | Phase 1 |
| Completed | Immunotoxin Therapy Before and After Surgery in Treating Patients With Recurrent Malignant Glioma NCT00036972 | Memorial Sloan Kettering Cancer Center | Phase 1 |
| Completed | Gefitinib in Treating Patients With Recurrent or Progressive CNS Tumors NCT00025675 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 2 |
| Completed | Study of Blood and Cheek Cell Samples From Patients With Glioma NCT01009307 | University of California, San Francisco | — |
| Completed | CCI-779 in Treating Patients With Malignant Glioma NCT00022724 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 / Phase 2 |
| Completed | Phase II Studies Of Donepezil And Ginkgo Biloba In Irradiated Brain Tumor NCT00070161 | Wake Forest University Health Sciences | Phase 2 |
| Completed | Chemotherapy in Treating Patients With Progressive or Recurrent Brain Tumors NCT00012038 | New Approaches to Brain Tumor Therapy Consortium | Phase 1 / Phase 2 |
| Unknown | Etoposide in Treating Young Patients With Relapsed Ependymoma NCT00278252 | Children's Cancer and Leukaemia Group | Phase 2 |
| Completed | ZD 1839 in Treating Patients With Glioblastoma Multiforme in First Relapse NCT00016991 | Duke University | Phase 2 |
| Terminated | Radiation Therapy Followed by Bleomycin in Treating Adult Patients With Newly Diagnosed Supratentorial Gliobla NCT00006916 | Radiation Therapy Oncology Group | Phase 2 |
| Completed | Taurolidine in Treating Patients With Recurrent or Progressive Glioma NCT00022360 | Memorial Sloan Kettering Cancer Center | Phase 1 |
| Completed | Topotecan in Treating Patients With Recurrent, Progressive, or Refractory Cancer That is Metastatic to the Lin NCT00025311 | NYU Langone Health | Phase 1 |
| Completed | Observation of Young Patients Who Are Undergoing Surgery for Craniopharyngioma NCT00258453 | German Society for Pediatric Oncology and Hematology GPOH gGmbH | N/A |
| Terminated | Imatinib Mesylate With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed or Recurre NCT00021229 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Completed | Motexafin Gadolinium Plus Radiation Therapy to the Brain in Treating Patients With Newly Diagnosed Glioblastom NCT00022256 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | Temozolomide, Thalidomide, and Celecoxib Following Radiation Therapy in Treating Patients With Newly Diagnosed NCT00047294 | Dana-Farber Cancer Institute | Phase 2 |
| Completed | Temozolomide and O6-benzylguanine in Treating Patients With Newly Diagnosed, Recurrent, or Progressive Anaplas NCT00006474 | Duke University | Phase 1 |
| Completed | Radiation Therapy Followed by Carmustine in Treating Patients Who Have Supratentorial Glioblastoma Multiforme NCT00006386 | Radiation Therapy Oncology Group | Phase 2 |
| Completed | NBI-3001 Followed by Surgery in Treating Patients With Recurrent Glioblastoma Multiforme NCT00014677 | Neurocrine Biosciences | Phase 2 |
| Completed | Arsenic Trioxide in Treating Patients With Advanced Neuroblastoma or Other Childhood Solid Tumors NCT00024258 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | Imatinib Mesylate in Treating Patients With Recurrent Malignant Glioma or Meningioma NCT00010049 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 / Phase 2 |
| Completed | Radiation Therapy Plus Carboplatin and Lobradimil in Treating Children With Newly Diagnosed Brain Stem Gliomas NCT00005602 | Children's Oncology Group | Phase 1 |
| Completed | Temozolomide Plus Irinotecan in Treating Patients With Recurrent Malignant Glioma NCT00006025 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 |
| Completed | CCI-779 in Treating Patients With Advanced Solid Tumors NCT00003712 | The University of Texas Health Science Center at San Antonio | Phase 1 |
| Completed | Glufosfamide in Treating Patients With Recurrent Glioblastoma Multiforme NCT00014300 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 2 |
| Completed | Radiation Therapy and Combination Chemotherapy in Treating Young Patients With Medulloblastoma, Supratentorial NCT00303810 | Universitätsklinikum Hamburg-Eppendorf | N/A |
| Unknown | Chemotherapy, Surgery, Radiation Therapy and Bone Marrow or Peripheral Stem Cell Transplantation in Treating P NCT00025324 | Children's Hospital Los Angeles | Phase 2 |
| Completed | Vaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain Tumor NCT00069940 | Dana-Farber Cancer Institute | Phase 1 |
| Completed | Radiation Therapy and Tamoxifen in Treating Adults With Newly Diagnosed Supratentorial Glioblastoma Multiforme NCT00006388 | Radiation Therapy Oncology Group | Phase 2 |
| Unknown | Combination Chemotherapy in Treating Patients With Recurrent Glioblastoma Multiforme NCT00014105 | Atlantic Health System | Phase 1 / Phase 2 |
| Completed | Busulfan in Treating Children and Adolescents With Refractory CNS Cancer NCT00006246 | Pediatric Brain Tumor Consortium | Phase 1 |
| Completed | Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation or Bone Marrow Transplantation in Tr NCT00025558 | NYU Langone Health | Phase 1 |
| Completed | Immunotoxin Therapy in Treating Patients With Malignant Glioma NCT00006268 | New Approaches to Brain Tumor Therapy Consortium | Phase 1 / Phase 2 |
| Completed | Fenretinide in Treating Patients With Recurrent Malignant Glioma NCT00006080 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 2 |
| Completed | EMD 121974 in Treating Patients With Progressive or Recurrent Glioma NCT00006093 | New Approaches to Brain Tumor Therapy Consortium | Phase 1 / Phase 2 |
| Terminated | SU5416 in Treating Children With Recurrent or Progressive Brain Tumors NCT00006247 | Pediatric Brain Tumor Consortium | Phase 1 |
| Unknown | Radiation Therapy Plus Hyperbaric Oxygen in Treating Patients With Newly Diagnosed Glioblastoma Multiforme NCT00006460 | Barrett Cancer Center | Phase 1 / Phase 2 |
| Completed | Temozolomide in Treating Patients With Brain Metastases NCT00005954 | Duke University | Phase 2 |
| Completed | Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Gli NCT00005952 | Duke University | Phase 1 / Phase 2 |
| Completed | Temozolomide Followed by Radiation Therapy in Treating Children With Newly Diagnosed Malignant CNS Tumors NCT00005955 | Duke University | Phase 2 |
| Terminated | Topotecan and Thalidomide in Treating Patients With Recurrent or Refractory Malignant Glioma NCT00014443 | Rush University Medical Center | Phase 2 |
| Completed | Carmustine Plus O6-benzylguanine in Treating Patients With Recurrent or Progressive Glioma NCT00005081 | Duke University | Phase 2 |
| Completed | Irinotecan Plus Temozolomide in Treating Patients With Recurrent Primary Malignant Glioma NCT00005951 | Duke University | Phase 1 |
| Completed | COL-3 in Treating Patients With Progressive or Recurrent Brain Tumors NCT00004147 | New Approaches to Brain Tumor Therapy Consortium | Phase 1 / Phase 2 |
| Completed | Efaproxiral Plus Carmustine in Treating Patients With Progressive or Recurrent Malignant Glioma NCT00005855 | New Approaches to Brain Tumor Therapy Consortium | Phase 1 / Phase 2 |
| Completed | Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multifor NCT00006353 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 3 |
| Completed | Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma NCT00006102 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Temozolomide Plus Thalidomide in Treating Patients With Recurrent or Progressive Brain Tumor NCT00006358 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 2 |
| Completed | Radiation Therapy Combined With Chemotherapy in Treating Patients With Anaplastic Astrocytoma or Mixed Gliomas NCT00004259 | Radiation Therapy Oncology Group | Phase 3 |
| Completed | Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors NCT00020150 | National Cancer Institute (NCI) | Phase 1 |
| Unknown | Carmustine Followed By Surgery in Treating Patients With Recurrent Supratentorial Malignant Glioma or Metastat NCT00009854 | Direct Therapeutics | Phase 1 / Phase 2 |
| Unknown | Carmustine in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme NCT00006656 | Direct Therapeutics | Phase 2 |
| Completed | Tipifarnib in Treating Patients With Recurrent or Progressive Malignant Glioma NCT00005859 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 / Phase 2 |
| Completed | Pyrazoloacridine Followed by Radiation Therapy in Treating Adults With Newly Diagnosed Supratentorial Glioblas NCT00006355 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 / Phase 2 |
| Completed | Pyrazoloacridine Plus Carboplatin in Treating Patients With Recurrent Glioma NCT00005976 | National Cancer Institute (NCI) | Phase 2 |
| Completed | O6-Benzylguanine and Carmustine Implants in Treating Patients With Recurrent Malignant Glioma NCT00004892 | National Cancer Institute (NCI) | Phase 1 |
| Completed | SU5416 in Treating Patients With Recurrent Astrocytoma or Mixed Glioma That Has Not Responded to Radiation The NCT00004868 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1 / Phase 2 |
| Completed | Nitrocamptothecin in Treating Patients With Glioblastoma Multiforme NCT00005826 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 2 |
| Completed | Combination Chemotherapy Plus Gene Therapy in Treating Patients With CNS Tumors NCT00005796 | Indiana University | Phase 1 |
| Completed | Radiolabeled Monoclonal Antibody in Treating Patients With Glioblastoma Multiforme or Anaplastic Astrocytoma NCT00004017 | Peregrine Pharmaceuticals | Phase 2 |
| Unknown | Temozolomide in Treating Patients With Recurrent or Progressive Malignant Glioma NCT00004204 | Herbert Irving Comprehensive Cancer Center | Phase 2 |
| Completed | Combination Chemotherapy, Surgery or Radiation Therapy, and Peripheral Stem Cell Transplant in Treating Patien NCT00025077 | Children's Cancer and Leukaemia Group | Phase 2 |
| Completed | Combination Chemotherapy Following Radiation Therapy in Treating Patients With Malignant Glioma NCT00005637 | Memorial Sloan Kettering Cancer Center | Phase 1 |
| Completed | Suramin Plus Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme NCT00004073 | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 2 |
| Completed | Gene Therapy in Treating Patients With Recurrent or Progressive Brain Tumors NCT00004080 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Acridine Carboxamide in Treating Patients With Recurrent Glioblastoma Multiforme NCT00004937 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 2 |
| Completed | Prinomastat Plus Temozolomide Following Radiation Therapy in Treating Patients With Newly Diagnosed Glioblasto NCT00004200 | Pfizer | Phase 2 |
| Completed | DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas NCT00004212 | Daiichi Sankyo | Phase 1 |
| Unknown | Phosphorus 32 in Treating Patients With Glioblastoma Multiforme NCT00004129 | Center for Molecular Medicine | Phase 1 |
| Terminated | Paclitaxel Plus Radiation Therapy in Treating Children With Newly Diagnosed Brain Stem Glioma NCT00031577 | Children's Hospital of Philadelphia | Phase 1 |
| Unknown | Radiation Therapy and Tamoxifen in Treating Children With Newly Diagnosed Brain Stem Glioma NCT00024336 | Children's Cancer and Leukaemia Group | Phase 2 |
| Completed | Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma NCT00005590 | Cancer Research Campaign Clinical Trials Centre | Phase 3 |
| Completed | Radiation Therapy, Chemotherapy, and Peripheral Stem Cell Transplantation in Treating Patients With Primitive NCT00003846 | Children's Oncology Group | Phase 2 |