| Withdrawn | Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma Neuroblastoma | Phase 1 | 2013-07-30 |
| Completed | BBI608 and Best Supportive Care vs Placebo and Best Supportive Care in Pretreated Advanced Colorectal Carcinom Colorectal Carcinoma | Phase 3 | 2013-05-10 |
| Completed | A Phase II Study of AT7519M, a CDK Inhibitor, in Patients With Relapsed Mantle Cell Lymphoma Mantle Cell Lymphoma | Phase 2 | 2012-09-14 |
| Completed | A Phase II Study of AT7519M, a CDK Inhibitor, in Patients With Relapsed and/or Refractory Chronic Lymphocytic Chronic Lymphocytic Leukemia | Phase 2 | 2012-08-27 |
| Completed | A Phase II Study of PF-03446962 in Patients With Advanced Malignant Pleural Mesothelioma Malignant Pleural Mesothelioma | Phase 2 | 2012-06-26 |
| Completed | A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration Resistant Prostate Cancer Prostate Cancer | Phase 2 | 2011-09-09 |
| Completed | Dexamethasone vs Placebo in the Prophylaxis of Radiation-Induced Pain Flare Following Palliative Radiotherapy Bone Metastases | Phase 3 | 2011-05-30 |
| Completed | A Study of PX-866 in Patients With Glioblastoma Multiforme at Time of First Relapse or Progression Glioblastoma | Phase 2 | 2011-04-01 |
| Completed | A Study of AT9283 in Patients With Relapsed or Refractory Multiple Myeloma Multiple Myeloma | Phase 2 | 2011-02-15 |
| Completed | Study of Foretinib in Combination With Lapatinib in Patients With Metastatic Breast Cancer Breast Cancer | Phase 1 / Phase 2 | 2010-10-27 |
| Completed | A Study of SB939 in Patients With Translocation-Associated Recurrent/Metastatic Sarcomas Metastatic Sarcoma | Phase 2 | 2010-10-21 |
| Completed | A Phase I Study of SB939 in Pediatric Patients With Refractory Solid Tumours and Leukemia Leukemia, Solid Tumours | Phase 1 | 2010-10-01 |
| Completed | A Study of Foretinib in Patients With Recurrent/Metastatic Breast Cancer Recurrent Breast Cancer | Phase 2 | 2010-09-02 |
| Completed | Phase II Study of Interleukin-21 (rIL-21) vs Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melan Melanoma | Phase 2 | 2010-08-05 |
| Completed | SB939 in Treating Patients With Recurrent or Metastatic Prostate Cancer Prostate Cancer | Phase 2 | 2010-06-28 |
| Terminated | Methadone Hydrochloride as First-Line Therapy in Treating Patients With Chronic Neuropathic Cancer Pain Nausea and Vomiting, Pain, Sleep Disorders | Phase 1 | 2010-06-17 |
| Completed | MET/VEGFR2 Inhibitor GSK1363089 and Erlotinib Hydrochloride or Erlotinib Hydrochloride Alone in Locally Advanc Lung Cancer | Phase 1 / Phase 2 | 2010-01-21 |
| Completed | PF-00299804 in Stage IIIB or Stage IV Non-Small Cell Lung Cancer Not Responding to Standard Therapy for Advanc Lung Cancer | Phase 3 | 2009-12-23 |
| Completed | MK-0646, Etoposide, and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer Lung Cancer | Phase 1 / Phase 2 | 2009-12-16 |
| Completed | Sunitinib in Treating Patients With Newly Diagnosed Stage II or Stage III Breast Cancer That Can Be Removed by Breast Cancer | Phase 2 | 2009-04-08 |
| Completed | Cediranib, Paclitaxel, and Carboplatin in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Ca Lung Cancer | Phase 3 | 2009-02-04 |
| Completed | Radiation + Cisplatin or Panitumumab in Locally Advanced Stage III or Stage IV Head and Neck Cancer Head and Neck Cancer | Phase 3 | 2008-12-30 |
| Completed | Ridaforolimus in Treating Patients With Recurrent Metastatic and/or Locally Advanced Endometrial Cancer Endometrial Cancer | Phase 2 | 2008-11-13 |
| Terminated | Gemcitabine With/Out Capecitabine in Locally Advanced, Unresectable, or Metastatic Biliary Cancer Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer | Phase 3 | 2008-10-10 |
| Completed | Bone Mineral Density in Postmenopausal Women at Increased Risk of Breast Cancer And Who Are Receiving Exemesta Breast Cancer, Osteoporosis | — | 2008-07-10 |
| Terminated | Androgen Suppression and Radiation With/Out Docetaxel in High-Risk Localized Prostate Cancer Prostate Cancer | Phase 3 | 2008-06-02 |
| Completed | Cetuximab With or Without Brivanib in Treating Patients With K-Ras Wild Type Tumours and Metastatic Colorectal Colorectal Cancer | Phase 3 | 2008-05-12 |
| Completed | AZD2281 and Irinotecan in Treating Patients With Locally Advanced or Metastatic Colorectal Cancer Colorectal Cancer | Phase 1 | 2008-01-02 |
| Completed | Interleukin-21 in Treating Patients With Metastatic or Recurrent Malignant Melanoma Melanoma (Skin) | Phase 2 | 2007-12-13 |
| Terminated | Observation or Radical Treatment in Patients With Prostate Cancer Prostate Cancer | N/A | 2007-12-06 |
| Completed | Sorafenib and Low Dose Cytarabine in Older Patients With Acute Myeloid Leukemia or High-Risk Myelodysplastic S Leukemia, Myelodysplastic Syndromes | Phase 1 / Phase 2 | 2007-11-27 |
| Completed | SB939 in Treating Patients With Locally Advanced or Metastatic Solid Tumors Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 2007-09-14 |
| Completed | Bortezomib, Combination Chemotherapy, and Rituximab as First-Line Therapy in Treating Patients With Stage III Lymphoma | Phase 2 | 2007-05-01 |
| Completed | Temozolomide + Everolimus in Newly Diagnosed, Recurrent, or Progressive Malignant Glioblastoma Multiforme Brain and Central Nervous System Tumors | Phase 1 | 2007-03-20 |
| Completed | Aurora Kinase Inhibitor AT9283 in Treating Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin's Non-Hodgkins Lymphoma, Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 2007-01-30 |
| Completed | Bortezomib and Gemcitabine in Treating Patients With Relapsed Mantle Cell Lymphoma Lymphoma | Phase 2 | 2007-01-16 |
| Completed | AT7519M in Treating Patients With Advanced or Metastatic Solid Tumors or Refractory Non-Hodgkin's Lymphoma Lymphoma, Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 2007-01-05 |
| Terminated | BCG With or Without Gefitinib in Treating Patients With High-Risk Bladder Cancer Bladder Cancer | Phase 3 | 2007-01-04 |
| Completed | Radiation in Stage I or Stage II Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery Lung Cancer | N/A | 2006-08-02 |
| Completed | AEG35156 and Docetaxel in Treating Patients With Locally Advanced, Metastatic, or Recurrent Solid Tumors Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 2006-07-27 |
| Completed | AZD0530 and Gemcitabine in Locally Advanced/Metastatic Pancreatic Cancer That Cannot Be Removed By Surgery Pancreatic Cancer | Phase 1 / Phase 2 | 2006-04-26 |
| Completed | Bone Mineral Density in Postmenopausal Women With Primary Breast Cancer Who Are Receiving Treatment on Clinica Breast Cancer, Osteoporosis | Phase 3 | 2006-04-24 |
| Completed | Lenalidomide and Melphalan in Treating Patients With Previously Untreated Multiple Myeloma Multiple Myeloma and Plasma Cell Neoplasm | Phase 2 | 2006-03-09 |
| Completed | AZD2171 and Standard Combination Chemotherapy in Advanced Non-Small Cell Lung Cancer or Colorectal Cancer Colorectal Cancer, Lung Cancer | Phase 1 | 2005-11-29 |
| Completed | Paclitaxel + Carboplatin With/Out Cediranib Maleate in Stage III or Stage IV Non-Small Cell Lung Cancer Lung Cancer | Phase 2 / Phase 3 | 2005-11-03 |
| Completed | OGX-011 and Docetaxel in Treating Women With Locally Advanced or Metastatic Breast Cancer Breast Cancer | Phase 2 | 2005-10-21 |
| Completed | Docetaxel and Prednisone With/Out OGX-011 in Recurrent or Metastatic Prostate Cancer That Did Not Respond to P Prostate Cancer | Phase 2 | 2005-09-28 |
| Completed | AEG35156 and Docetaxel in Treating Patients With Solid Tumors Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 2005-06-09 |
| Completed | Everolimus in Treating Patients WIth Recurrent or Metastatic Breast Cancer Breast Cancer | Phase 2 | 2005-05-10 |
| Completed | SB-715992 in Treating Patients With Locally Advanced, Recurrent, or Metastatic Liver Cancer Liver Cancer | Phase 2 | 2005-03-08 |
| Completed | AZD2171 + Chemotherapy in Advanced NSCLC, Colorectal Cancer, or Other Cancer Suitable for Treatment With Capec Colorectal Cancer, Lung Cancer, Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 2005-01-21 |
| Completed | Exemestane in Preventing Cancer in Postmenopausal Women at Increased Risk of Developing Breast Cancer Breast Cancer | Phase 3 | 2004-12-03 |
| Completed | SB-715992 in Treating Patients With Metastatic or Recurrent Malignant Melanoma Melanoma (Skin) | Phase 2 | 2004-11-01 |
| Completed | Sorafenib in Treating Patients With Metastatic or Recurrent Prostate Cancer Prostate Cancer | Phase 2 | 2004-08-10 |
| Completed | 3-AP in Treating Patients With Previously Untreated Locally Recurrent or Metastatic Renal Cell Carcinoma Kidney Cancer | Phase 2 | 2004-05-11 |
| Completed | Adjuvant Erlotinib After Completing Chemoradiotherapy in Locally Advanced Squamous Cell Carcinoma of the Head Head and Neck Cancer | Phase 1 | 2004-03-02 |
| Completed | Single vs Multiple-Fraction Therapy in Treating Patients With Previously Irradiated Painful Bone Metastases Metastatic Cancer, Pain | N/A | 2004-01-22 |
| Completed | Cetuximab + Best Supportive Care Compared With Best Supportive Care Alone in Metastatic Epidermal Growth Facto Colorectal Cancer, Quality of Life | Phase 3 | 2003-12-30 |
| Completed | Epirubicin, Docetaxel, and Pegfilgrastim in Treating Women With Locally Advanced or Inflammatory Breast Cancer Breast Cancer | Phase 1 / Phase 2 | 2003-11-03 |
| Completed | Cisplatin or Carboplatin Combined With Gemcitabine in Locally Advanced, Recurrent, or Metastatic Malignant Sal Head and Neck Cancer | Phase 2 | 2003-10-27 |
| Completed | Chemotherapy Before Autologous Stem Cell Transplantation +/- Rituximab in Relapsed or Refractory Aggressive No Lymphoma | Phase 3 | 2003-08-27 |
| Completed | Perifosine in Treating Patients With Metastatic or Recurrent Malignant Melanoma Melanoma (Skin) | Phase 2 | 2003-06-20 |
| Completed | Perifosine in Treating Patients With Metastatic or Locally Advanced Soft Tissue Sarcoma Endometrial Cancer, Sarcoma | Phase 2 | 2003-06-09 |
| Completed | Exemestane or Anastrozole in Treating Postmenopausal Women Who Have Undergone Surgery for Primary Breast Cance Breast Cancer | Phase 3 | 2003-06-06 |
| Completed | OGX-011 and Docetaxel in Treating Patients With Metastatic or Locally Recurrent Solid Tumors Bladder Cancer, Breast Cancer, Kidney Cancer | Phase 1 | 2003-04-04 |
| Completed | Hormone Therapy and OGX-011 Before Radical Prostatectomy in Treating Patients With Prostate Cancer Prostate Cancer | Phase 1 | 2002-12-10 |
| Completed | Bortezomib in Treating Patients With Mantle Cell Lymphoma Lymphoma | Phase 2 | 2002-11-19 |
| Completed | Thalidomide and Prednisone After Autologous Stem Cell Transplantation Multiple Myeloma Multiple Myeloma and Plasma Cell Neoplasm | Phase 3 | 2002-10-15 |
| Completed | Fludarabine in Treating Patients With Chronic Lymphocytic Leukemia Leukemia | Phase 2 | 2002-08-08 |
| Completed | Bortezomib in Treating Patients With Waldenstrom's Macroglobulinemia Lymphoma | Phase 2 | 2002-08-01 |
| Completed | SarCNU in Treating Patients With Recurrent Malignant Glioma Brain and Central Nervous System Tumors | Phase 2 | 2002-01-10 |
| Completed | Erlotinib and Carboplatin in Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cavity Cancer | Phase 2 | 2002-01-10 |
| Completed | Vitamin E, Selenium, and Soy Protein in Preventing Cancer in Patients With High-Grade Prostate Neoplasia Precancerous/Nonmalignant Condition, Prostate Cancer | Phase 3 | 2001-11-28 |
| Completed | SarCNU in Treating Patients With Recurrent or Metastatic Colorectal Cancer Colorectal Cancer | Phase 2 | 2001-10-30 |
| Completed | Gemcitabine With/Out Erlotinib in Unresectable Locally Advanced/Metastatic Pancreatic Cancer Pancreatic Cancer | Phase 3 | 2001-10-29 |
| Completed | Combination Chemotherapy Regimens in Ovarian Epithelial Cancer, Primary Peritoneal Cancer, or Fallopian Tube C Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cavity Cancer | Phase 3 | 2001-08-31 |
| Completed | Exemestane in Reducing Breast Density in Postmenopausal Women at Risk for Breast Cancer Breast Cancer | N/A | 2001-08-01 |
| Completed | Combination Chemotherapy With or Without Rituximab in Non-Hodgkin's Lymphoma Lymphoma | Phase 3 | 2001-05-08 |
| Completed | ZD 1839 in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy Prostate Cancer | Phase 2 | 2001-04-24 |
| Completed | Ondansetron With/Out Dexamethasone to Prevent Vomiting in Patients Receiving Radiation to the Upper Abdomen Cancer | Phase 3 | 2001-02-28 |
| Completed | Radiation Therapy in Relapsed or Refractory Non-Hodgkin's Lymphoma Who Have Undergone Stem Cell Transplantatio Lymphoma | N/A | 2001-01-31 |
| Completed | Combination Chemotherapy in Hodgkin's Disease or Non-Hodgkin's Lymphoma Not Responding to Previous Treatment Lymphoma | Phase 2 | 2000-12-12 |
| Completed | Letrozole in Preventing Breast Cancer in Postmenopausal Women Who Are at Increased Risk for Breast Cancer Due Breast Cancer | Phase 2 | 2000-12-05 |
| Completed | Combination Chemotherapy With or Without Colony-stimulating Factors in Treating Women With Breast Cancer Breast Cancer | Phase 3 | 2000-12-04 |
| Completed | Lurtotecan Liposome in Treating Patients With Advanced or Recurrent Ovarian Epithelial Cancer Fallopian Tube Cancer, Ovarian Cancer, Peritoneal Cavity Cancer | Phase 2 | 2000-10-31 |
| Completed | Thalidomide and Prednisone Following Peripheral Stem Cell Transplantation in Treating Patients With Multiple M Multiple Myeloma and Plasma Cell Neoplasm | Phase 2 | 2000-07-12 |
| Completed | Flavopiridol in Treating Patients With Recurrent, Locally Advanced, or Metastatic Soft Tissue Sarcoma Sarcoma | Phase 2 | 2000-07-04 |
| Completed | Flavopiridol in Treating Patients With Metastatic Malignant Melanoma Melanoma (Skin) | Phase 2 | 2000-07-04 |
| Completed | Paclitaxel + Carboplatin With/ut BMS-275291 in Advanced or Metastatic Non-small Cell Lung Cancer Lung Cancer | Phase 2 / Phase 3 | 2000-04-04 |
| Completed | Liposomal Lurtotecan Plus Cisplatin in Treating Patients With Advanced or Metastatic Solid Tumors Head and Neck Cancer, Lung Cancer, Ovarian Cancer | Phase 1 | 2000-03-22 |
| Completed | Radiation Therapy in Treating Women Who Have Undergone Surgery for Early-Stage Invasive Breast Cancer Breast Cancer | N/A | 2000-03-09 |
| Completed | Flavopiridol in Treating Patients With Previously Untreated or Relapsed Mantle Cell Lymphoma Lymphoma | Phase 2 | 2000-01-24 |
| Completed | Letrozole in Treating Women With Recurrent or Metastatic Endometrial Cancer Endometrial Cancer | Phase 2 | 2000-01-19 |
| Completed | Oral Mucositis in Patients Receiving Radiation Therapy for Cancer of the Mouth, Pharynx, or Larynx Head and Neck Cancer, Oral Complications | Phase 3 | 1999-08-02 |
| Completed | Lurtotecan Liposome in Treating Patients With Advanced Solid Tumors Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 1999-02-25 |
| Completed | MG98 in Treating Patients With Advanced Solid Tumors Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 1999-02-22 |
| Completed | ISIS 5132 in Treating Patients With Metastatic or Recurrent Ovarian Cancer Ovarian Cancer | Phase 2 | 1999-02-01 |
| Completed | Hormone Therapy in Treating Patients With Rising PSA Levels Following Radiation Therapy for Prostate Cancer Prostate Cancer | Phase 3 | 1999-01-05 |
| Completed | Letrozole After Tamoxifen in Treating Women With Breast Cancer Breast Cancer | Phase 3 | 1998-08-24 |
| Completed | Treatment for Chronic Pain in Patients With Advanced Cancer Chronic Myeloproliferative Disorders, Leukemia, Lymphoma | Phase 3 | 1998-06-11 |
| Terminated | Pilocarpine in Treating Patients With Dry Mouth Caused by Opioids Oral Complications, Quality of Life | Phase 3 | 1998-05-22 |
| Completed | Theophylline in Treating Cancer Patients With Shortness of Breath Pulmonary Complications, Quality of Life, Unspecified Adult Solid Tumor, Protocol Specific | Phase 3 | 1998-03-24 |
| Completed | Topotecan in Treating Patients With Recurrent Brain Tumors Brain and Central Nervous System Tumors | Phase 2 | 1997-12-08 |
| Completed | Combination Chemotherapy in Treating Pain in Hormone Refractory Metastatic Prostate Cancer Pain, Prostate Cancer, Quality of Life | Phase 3 | 1997-11-24 |
| Completed | Radiation Therapy to Relieve Symptoms in Patients With Non-small Cell Lung Cancer Fatigue, Lung Cancer, Nausea and Vomiting | Phase 3 | 1997-08-01 |
| Completed | High Dose Chemotherapy Plus Peripheral Stem Cell Transplantation Compared With Standard Therapy in Treating Wo Breast Cancer | Phase 3 | 1997-04-25 |
| Completed | Marimastat Following Chemotherapy in Treating Patients With Small Cell Lung Cancer Lung Cancer | Phase 3 | 1997-01-31 |
| Completed | Tamoxifen With or Without Octreotide in Treating Postmenopausal Women With Stage I, Stage II, or Stage III Bre Breast Cancer | Phase 3 | 1996-09-24 |
| Completed | Docetaxel and Epirubicin With and Without G-CSF in Treating Women With Metastatic Breast Cancer Breast Cancer, Neutropenia | Phase 1 | 1996-08-12 |
| Completed | Radiation or Observation Only in Endometrial Cancer Who Have Undergone Surgery Endometrial Cancer | N/A | 1996-07-04 |
| Completed | Combination Chemotherapy in Treating Patients With Multiple Myeloma Multiple Myeloma and Plasma Cell Neoplasm | Phase 3 | 1995-06-02 |
| Completed | Hormone Therapy With or Without Surgery or Radiation Therapy in Treating Patients With Prostate Cancer Prostate Cancer | Phase 3 | 1995-02-08 |
| Completed | Immediate Compared With Delayed Chemotherapy in Advanced Colorectal Cancer Without Signs or Symptoms of Diseas Colorectal Cancer | Phase 3 | 1994-07-15 |
| Completed | Vinorelbine + Cisplatin or No Further Therapy in Non-small Cell Lung Cancer That Has Been Surgically Removed Lung Cancer | Phase 3 | 1994-07-07 |
| Completed | Radiation Therapy and Chemotherapy in Treating Patients With Hodgkin's Disease Hodgkin Lymphoma | Phase 3 | 1994-01-25 |
| Completed | Tamoxifen in Treating Women With High-Risk Breast Cancer Breast Cancer | Phase 3 | 1993-07-20 |