| Not Yet Recruiting | Deployment and Clinical Evaluation of an AI-powered Digital Oncology Biomarker Tool to guidE Treatment in TNBC Triple Negative Breast Cancer | — | 2026-08-01 |
| Not Yet Recruiting | The BALANCE Study: BlAck and Mixed Men's Lived Experience With Prostate cANCEr-Diversity in Prostate Cancer PR Prostate Cancer | — | 2026-05-05 |
| Recruiting | 5G-PEARL: Paxalisib in Malignant Brain Tumours Malignant Primary Gliomas, Glioblastoma Multiforme (GBM) | Phase 1 / Phase 2 | 2026-01-19 |
| Not Yet Recruiting | The eValuation of Sources of vIBRAtioN for Vibrational Shear Wave elasTography Head and Neck Cancer (H&Amp;Amp;N), Lymph Nodes | — | 2025-09-01 |
| Recruiting | Investigating Idetrexed and Olaparib in Patients With Ovarian Cancer High Grade Serous Ovarian Cancer | Phase 1 | 2025-08-01 |
| Recruiting | The i4i PRODICT® Study: Evaluation of the i4i PRODICT® Test in Different Ethnic Groups (The i4i PRODICT® Study Prostate Cancer | — | 2025-06-02 |
| Recruiting | Investigating SX-682 in Combination With Apalutamide in Metastatic Castration-resistant Prostate Cancer Metastatic Castrate-Resistant Prostate Cancer (mCRPC) | Phase 1 / Phase 2 | 2025-04-28 |
| Recruiting | 5G-RUBY: Avutometinib and Defactinib in Malignant Brain Tumours Glioblastoma Multiforme (GBM), Glioblastoma Multiform (Grade IV Astrocytoma), Diffuse Hemispheric Glioma, H3 G34-Mutant | Phase 1 / Phase 2 | 2024-11-15 |
| Recruiting | 5G-EMERALD: Amivantamab in Malignant Brain Tumours Malignant Primary Gliomas, Glioblastoma Multiform (Grade IV Astrocytoma), Diffuse Hemispheric Glioma, H3 G34-Mutant | Phase 1 | 2024-10-09 |
| Recruiting | The COherence of Scatter Identification and Exclusion Algorithm Study Steatohepatitis, Nonalcoholic | — | 2024-08-27 |
| Recruiting | SBRT Alone or Followed by Niraparib for Oligometastases or Oligoprogression in Ovarian Cancer Following PARPi Ovarian Cancer Recurrent | Phase 2 | 2024-06-20 |
| Recruiting | Combination Study of Antibiotics With Enzalutamide (PROMIZE) Metastatic Castration-Resistant Prostate Cancer (mCRPC) | Phase 1 / Phase 2 | 2023-11-02 |
| Recruiting | Microbiome Molecular Charaterisation Prostate Cancer | — | 2023-10-23 |
| Recruiting | The Active Surveillance Study Prostate Cancer | — | 2023-08-22 |
| Recruiting | POTENT - Tepotinib in Combination With Pembrolizumab in NSCLC Advanced Cancer, Non Small Cell Lung Cancer | Phase 1 | 2023-05-03 |
| Recruiting | A Trial of 5 Fraction Prostate SBRT Versus 5 Fraction Prostate and Pelvic Nodal SBRT Prostate Cancer | Phase 3 | 2022-09-09 |
| Recruiting | ASTEROID: A Trial of ASTX660 in Combination With Pembrolizumab Advanced Cancer, Cervical Cancer, Triple Negative Breast Cancer | Phase 1 | 2022-03-02 |
| Recruiting | Hypofractionated Expedited Radiotherapy for Men With localisEd proState Cancer Prostate Cancer | N/A | 2021-07-29 |
| Completed | Digital Delivery of Information About Genetic Testing for Breast Cancer Breast Neoplasm Female | N/A | 2021-07-05 |
| Unknown | CORONADO (Circulating tumOur pROtein quaNtification cApillary blooD cOvid-19) Multiple Myeloma | — | 2021-03-04 |
| Active Not Recruiting | PreOperative Endocrine Therapy for Individualised Care With Abemaciclib Breast Cancer Female | Phase 3 | 2020-12-23 |
| Terminated | Abiraterone Acetate in Combination With Tildrakizumab Metastatic Castration Resistant Prostate Cancer | Phase 1 / Phase 2 | 2020-12-01 |
| Unknown | Exploring the Mechanisms and Dynamics of Clonal Evolution Leading to Recurrence in Prostate Cancer Prostate Cancer Recurrent | — | 2020-11-26 |
| Recruiting | Myeloma Novel Drug Discovery Ver 1.2 Multiple Myeloma | — | 2020-07-22 |
| Recruiting | KORTUC Phase II - Intra-tumoural Radiation Sensitizer in Patients With Locally Advanced/Recurrent Breast Cance Breast Cancer | Phase 2 | 2020-06-16 |
| Unknown | Molecular Stratification Profiling Protocol in Metastatic Castration Resistant Prostate Cancer (mCRPC) - MAEST Metastatic Prostate Cancer, Castration-resistant Prostate Cancer | — | 2019-11-28 |
| Active Not Recruiting | ATr Inhibitor in Combination With Olaparib/Durvalumab (MEDI4736) in Gynaecological Cancers With ARId1A Loss or Gynaecological Cancers | Phase 2 | 2019-11-27 |
| Recruiting | PHOENIX DDR/Anti-PD-L1 Trial: A Pre-surgical Window of Opportunity and Post-surgical Adjuvant Biomarker Study Breast Neoplasm, Triple Negative Breast Cancer (TNBC), HRD | Phase 2 | 2019-10-15 |
| Unknown | Exploring the Link Between Cancer Genetics and PPSP Cancer-related Pain, Chronic Post Cancer Surgery Pain, Breast Cancer | — | 2019-07-01 |
| Active Not Recruiting | Transcriptional Responses as an Indicator of Individualised Responses to Radiation Effects (RTGene 2) Cancer | — | 2019-05-09 |
| Active Not Recruiting | The BARCODE 1 Study (Full Study): The Use of Genetic Profiling to Guide Prostate Cancer Targeted Screening. Prostate Cancer | — | 2019-03-14 |
| Recruiting | Precision Medicine in the Prostate Cancer Care Pathway Prostate Cancer, Genetic Predisposition | — | 2019-02-14 |
| Unknown | Prospective Evaluation of Radiotherapy Using Magnetic Resonance Image Guided Treatment Cancer | N/A | 2019-01-11 |
| Unknown | Trial of Pembrolizumab in Metastatic Castration Resistant Prostate Cancer Castration-resistant Prostate Cancer | Phase 2 | 2018-11-27 |
| Unknown | The eValuation of Image Guidance of Stereotactic Body Radiotherapy Using Ultrasound: Assessment in Liver Liver Neoplasms | — | 2018-09-01 |
| Active Not Recruiting | A Trial of Ipatasertib in Combination With Atezolizumab Solid Tumor, Glioblastoma Multiforme, Prostate Cancer Metastatic | Phase 1 / Phase 2 | 2018-08-13 |
| Withdrawn | Magnetic Resonance Guided High Intensity Focused Ultrasound (MRgHIFU) for Pain Palliation of Bone Metastases Cancer, Bone Metastases | N/A | 2018-03-16 |
| Recruiting | PUMA (Paediatric Osseous Marrow Assessment) Leukaemia | — | 2018-03-05 |
| Terminated | The Role of Hypoxia as a Selective Pressure for TP53 Mutations Endometrial Cancer | — | 2018-02-06 |
| Unknown | A Trial Using ctDNA Blood Tests to Detect Cancer Cells After Standard Treatment to Trigger Additional Treatmen Triple Negative Breast Cancer | Phase 2 | 2017-12-21 |
| Active Not Recruiting | Phase I Trial of Defactinib and VS-6766. NSCLC, Low Grade Serous Ovarian Cancer, Endometrioid Carcinoma | Phase 1 | 2017-12-12 |
| Unknown | Stereotactic Body Radiotherapy for the Treatment of OPD NSCLC | Phase 2 / Phase 3 | 2017-11-27 |
| Terminated | Combination Study of AZD5069 and Enzalutamide. Metastatic Castration Resistant Prostate Cancer | Phase 1 / Phase 2 | 2017-11-13 |
| Completed | Pimo Study: Extracellular Vesicle-based Liquid Biopsy to Detect Hypoxia in Tumours Cancer | N/A | 2017-11-10 |
| Recruiting | PRIMER: Development of Daily Online Magnetic Resonance Imaging for Magnetic Resonance Image Guided Radiotherap Adenocarcinoma | — | 2017-10-17 |
| Active Not Recruiting | The BARCODE 2 Study - The Use of Genetic Profiling to Guide Prostate Cancer Treatment Hormone Refractory Prostate Cancer | Phase 2 | 2017-05-25 |
| Recruiting | International Penile Advanced Cancer Trial (International Rare Cancers Initiative Study) Squamous Cell Carcinoma of the Penis, Usual Type | Phase 3 | 2017-05-12 |
| Completed | KORTUC: Intra-tumoural Hydrogen Peroxide as a Radiation Sensitizer in Patients With Locally Advanced/Recurrent Breast Cancer | Phase 1 / Phase 2 | 2017-01-19 |
| Terminated | Utilising CTC Counts to Optimize Systemic Therapy of Metastatic Prostate Cancer Adenocarcinoma of the Prostate | Phase 3 | 2017-01-11 |
| Unknown | The UK Plasma Based Molecular Profiling of Advanced Breast Cancer to Inform Therapeutic CHoices (plasmaMATCH) Advanced Breast Cancer | Phase 2 | 2016-12-15 |
| Completed | Feasibility Study Testing Transcriptional Responses as an Indicator of Individualised Responses to Radiation E Cancer | — | 2016-09-12 |
| Completed | Imaging NSCLC Treatment Response to Immunotherapy Cancer | — | 2016-05-31 |
| Completed | MR-HIFU for Recurrent Gynaecological Cancer Cervical Cancer, Endometrial Cancer, Uterine Cancer | N/A | 2016-05-01 |
| Active Not Recruiting | The BARCODE 1 Pilot Study Prostate Cancer | — | 2016-04-29 |
| Active Not Recruiting | Study of Tumour Focused Radiotherapy for Bladder Cancer Bladder Cancer | Phase 2 | 2015-10-21 |
| Recruiting | The GENPET Study - An Imaging Study of FCH-PET-CT in Men With Prostate Cancer and a DNA Repair Gene Mutation. Prostate Cancer, BRCA Mutation, Mismatch Repair Gene Mutation | — | 2015-10-15 |
| Completed | Quantification of Breast RadioTherapy Associated Late Toxicity Using Novel UltraSound Techniques Breast Radiotherapy Toxicity | — | 2015-10-01 |
| Completed | Evaluation of Clarity Ultrasound Guidance for Prostate Therapy Prostate Cancer | — | 2015-05-15 |
| Terminated | Evolution of Resistance to Systemic Therapies in Patients With Breast Cancer Metastatic Breast Cancer | — | 2015-05-11 |
| Completed | Imaging in Clinical Trials - a Questionnaire Study to Assess Impact of Imaging Regimes on Patient Participatio Cancer | — | 2015-04-01 |
| Completed | Imageguided Theranostics in Multiple Myeloma Cancer, Myeloma | — | 2015-03-26 |
| Recruiting | The PROFILE Study: Germline Genetic Profiling: Correlation With Targeted Prostate Cancer Screening and Treatme Prostate Cancer, Prostate Biopsy, Genetic Counselling | — | 2015-03-09 |
| Unknown | A Study of Enzalutamide in Combination With AZD5363 in Patients With mCRPC Adenocarcinoma of the Prostate | Phase 2 | 2014-12-01 |
| Unknown | Investigating Bladder Chemotherapy Instead of Surgery for Low Risk Bladder Cancer Bladder Cancer | Phase 2 | 2014-10-01 |
| Recruiting | Analysing Outcomes After Prostate Cancer Diagnosis and Treatment in Carriers of Rare Germline Mutations Prostate Cancer | — | 2014-09-01 |
| Completed | Study of Weekly Radiotherapy for Bladder Cancer Bladder Cancer | N/A | 2014-04-01 |
| Completed | A Phase II Trial of Vinflunine Chemotherapy in Locally-advanced and Metastatic Carcinoma of the Penis (VinCaP) Locally-advanced or Metastatic Penile Neoplasms | Phase 2 | 2014-03-17 |
| Completed | MR-HIFU for Bone Metastases Cancer, Bone Metastases | N/A | 2014-01-01 |
| Completed | Apparent Diffusion Coefficient as a Prognostic Biomarker in Cervical Cancer Cancer | — | 2013-10-02 |
| Completed | Lactate Imaging as a Tumour Biomarker Cancer | — | 2013-09-01 |
| Completed | Preoperative Imaging in Retroperitoneal Sarcoma Cancer | — | 2013-07-01 |
| Completed | Magnetic Resonance Imaging Screening in Li Fraumeni Syndrome Li-Fraumeni Syndrome | — | 2012-10-01 |
| Completed | A Phase II Study of Axitinib in Patients With Metastatic Renal Cell Cancer Unsuitable for Nephrectomy Clear-cell Metastatic Renal Cell Carcinoma | Phase 2 | 2012-10-01 |
| Completed | Diffusion-weighted Imaging Study in Cancer of the Ovary Ovarian Cancer, Peritoneal Metastases | — | 2012-08-01 |
| Unknown | TOPARP: A Phase II Trial of Olaparib in Patients With Advanced Castration Resistant Prostate Cancer Adenocarcinoma of the Prostate | Phase 2 | 2012-07-01 |
| Unknown | A Phase III Randomised Trial of Peri-Operative Chemotherapy Versus sUrveillance in Upper Tract Urothelial Canc Transitional Cell Carcinoma of Ureter | Phase 3 | 2012-05-01 |
| Unknown | A Trial of Cediranib in the Treatment of Patients With Alveolar Soft Part Sarcoma (CASPS) Alveolar Soft-part Sarcoma | Phase 2 | 2011-07-01 |
| Unknown | A Study of Prostate and pelvIs Versus prOsTate Alone Treatment for Locally Advanced Prostate Cancer Prostate Cancer | Phase 2 | 2011-06-01 |
| Completed | Assessing Treatment Response in Breast Cancer With Functional Imaging Breast Cancer | — | 2010-09-01 |
| Unknown | Trastuzumab or Lapatinib Ditosylate in Treating Women With Early Breast Cancer Breast Cancer | Phase 3 | 2010-04-01 |
| Completed | Trial of 1 Cycle of Adjuvant BEP Chemotherapy in High Risk, Stage 1 Non-seminomatous Germ Cell Testis Tumours Stage I Testicular Non-Seminomatous Germ Cell Tumor | Phase 3 | 2010-02-01 |
| Completed | A Trial Looking at Nilotinib to Treat Acral and Mucosal Melanoma Skin Cancer That Has Spread Mucosal Lentiginous Melanoma, Acral Lentiginous Malignant Melanoma | Phase 2 | 2009-12-01 |
| Unknown | 3-Dimensional Conformal Radiation Therapy in Treating Patients With Bladder Cancer Who Have Undergone Transure Bladder Cancer | Phase 1 | 2009-05-01 |
| Active Not Recruiting | Trial of Perioperative Endocrine Therapy - Individualising Care Breast Cancer | Phase 3 | 2008-09-01 |
| Unknown | Intensity-Modulated Radiation Therapy or 3-Dimensional Conformal Radiation Therapy in Decreasing Hearing Loss Head and Neck Cancer, Ototoxicity, Radiation Toxicity | Phase 3 | 2008-08-01 |
| Unknown | Radiation Therapy in Treating Women Who Have Undergone Breast Conservation Surgery and Systemic Therapy for Ea Breast Cancer | Phase 3 | 2008-08-01 |
| Unknown | Triple Negative Breast Cancer Trial Breast Cancer | Phase 3 | 2008-01-01 |
| Completed | MR Characterisation/Localisation of Breast Cancer Breast Cancer | — | 2007-11-01 |
| Completed | Radiation Therapy or Surgery in Treating Patients Receiving Chemotherapy for Bladder Cancer Bladder Cancer | Phase 3 | 2007-07-01 |
| Completed | Short-term Presurgical Study to Assess Molecular Predictors of Lapatinib's Effects in Primary Breast Cancer Breast Cancer | Phase 2 | 2007-06-01 |
| Unknown | Radiation Therapy in Women With Low Risk Early-Stage Breast Cancer Who Have Undergone Breast Conservation Surg Breast Cancer | N/A | 2007-05-03 |
| Unknown | Combination Chemotherapy in Treating Patients With Early Stage Breast Cancer That Has Been Removed By Surgery Breast Cancer | Phase 3 | 2005-12-16 |
| Unknown | 17-Dimethylaminoethylamino-17-Demethoxygeldanamycin (17-DMAG) in Treating Patients With Metastatic Solid Tumor Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 2005-10-01 |
| Unknown | Combination Chemotherapy With or Without Surgery and Radiation Therapy in Treating Patients With Mesothelioma Malignant Mesothelioma | N/A | 2005-05-01 |
| Active Not Recruiting | The IMPACT Study - Identification of Men With a Genetic Predisposition to ProstAte Cancer Prostate Cancer, BRCA Mutation, Mismatch Repair Gene Mutation | — | 2005-03-01 |
| Completed | Radiation Therapy in Treating Women With Localized Breast Cancer Breast Cancer | N/A | 2004-10-05 |
| Unknown | Hyperbaric Oxygen Therapy Compared With Standard Therapy in Treating Chronic Arm Lymphedema in Patients Who Ha Breast Cancer, Lymphedema, Perioperative/Postoperative Complications | Phase 2 | 2004-04-01 |
| Unknown | Adjuvant Radiation Therapy Compared With Observation After Surgery in Treating Women With Estrogen Receptor Po Breast Cancer | Phase 2 | 2004-04-01 |
| Completed | Study of Faslodex +/- Concomitant Arimidex v Exemestane Following Progression on Non-steroidal Aromatase Inhib Breast Cancer | Phase 3 | 2004-03-26 |
| Unknown | Intensity-Modulated Radiation Therapy in Treating Patients With Localized Prostate Cancer Prostate Cancer | N/A | 2002-10-18 |
| Completed | Temozolomide Compared to Procarbazine, Lomustine, and Vincristine in Treating Patients With Recurrent Malignan Brain and Central Nervous System Tumors | Phase 3 | 2002-10-01 |
| Completed | Combination Chemotherapy With or Without Rituximab in Treating Patients With Mantle Cell Lymphoma Lymphoma | Phase 2 | 2002-10-01 |
| Completed | Positron Emission Tomography in Detecting Testicle Cancer Testicular Germ Cell Tumor | N/A | 2002-05-01 |
| Unknown | Hormone Replacement Therapy in Relieving Menopausal Symptoms in Postmenopausal Women With Previous Stage I or Breast Cancer, Hot Flashes, Menopausal Symptoms | N/A | 2002-03-01 |
| Unknown | Combination Chemotherapy in Treating Women With Resected Breast Cancer Breast Cancer | Phase 2 | 2001-02-01 |
| Completed | Raloxifene and Goserelin in Preventing Breast Cancer in Women With a Family History of Breast Cancer Breast Cancer | N/A | 2000-03-01 |
| Completed | Leucovorin and Fluorouracil Compared With Observation in Treating Patients With Colorectal Cancer That Has Bee Colorectal Cancer | Phase 3 | 1997-10-01 |
| Completed | Interferon Alfa or No Further Therapy Following Surgery in Treating Patients With Stage II, Stage III, or Recu Melanoma (Skin) | Phase 3 | 1995-10-01 |
| Completed | Tamoxifen, Ovarian Ablation, and/or Chemotherapy in Treating Women With Stage I, Stage II, or Stage IIIA Breas Breast Cancer | Phase 3 | 1993-06-01 |
| Unknown | Study of Blood and Tumor Samples From Men With an Inherited Risk of Prostate Cancer Prostate Cancer | — | 1993-06-01 |
| Active Not Recruiting | UK Genetic Prostate Cancer Study: Epidemiology and Molecular Genetics Studies Prostate Cancer | — | 1993-01-01 |