NCT01964677

MR-HIFU for Bone Metastases

Magnetic Resonance-Guided High Intensity Focused Ultrasound for Palliation of Painful Skeletal Metastases - a Multicenter Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Institute of Cancer Research, United Kingdom · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to evaluate effectiveness of the Philips Sonalleve MR-HIFU device for the palliation of pain in patients with bone metastases. Magnetic Resonance Imaging-guided High Intensity Focused Ultrasound (MR-HIFU) uses ultrasound to palliate pain caused by bone metastases. The main palliative mechanism of the method is due to local bone denervation, caused by the heat denaturation of the periosteum layer in the treated area. The importance of this therapy is that it offers a non-invasive, focal therapy, avoiding side-effects to surrounding normal tissue that occur with radiation therapy or the need for needle insertion as with radio-frequency(RF)ablation. The study hypothesis is that MR-HIFU will be effective in treating the pain associated with bone metastases

Conditions

• Cancer
• Bone Metastases

Interventions

Type	Name	Description
DEVICE	Magnetic Resonance Image-guided High Intensity Focused Ultrasound (MR-HIFU)

Timeline

• Start date: 2014-01-01
• Primary completion: 2016-11-14
• Completion: 2016-11-14
• First posted: 2013-10-17
• Last updated: 2017-08-22

Locations

1 site across 1 country: United Kingdom