| Not Yet Recruiting | Feasibility and Acceptability of Collecting Sociodemographic Data in CCTG Trials Cancer | — | 2026-06-30 |
| Not Yet Recruiting | GCAR1, a Chimeric Antigen Receptor (CAR) T-CELL Therapy for Relapsed/Refractory GPNMB-Expressing Solid Tumours Alveolar Soft Part Sarcoma, Renal Cell Carcinoma, Triple Negative Breast Cancer | Phase 1 | 2026-05-01 |
| Not Yet Recruiting | Canadian Initiative to Measure, Predict and Assess Cancer Treatment Outcomes in Patients Treated With Immuno-O Carcinoma | — | 2026-04-30 |
| Recruiting | Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Ad Colorectal Cancer | Phase 3 | 2026-03-31 |
| Not Yet Recruiting | Sonrotoclax Plus Zanubrutinib in Patients With Relapsed/Refractory Mantle Cell Lymphoma Planned for Standard o Mantle Cell Lymphoma | Phase 2 | 2026-03-31 |
| Recruiting | Radiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung Cancer Non-small Cell Lung Cancer | Phase 3 | 2025-12-16 |
| Recruiting | STRIDE (Durvalumab + Tremelimumab) With Lenvatinib vs STRIDE Alone in Unresectable Hepatocellular Carcinoma Hepatocellular Carcinoma | Phase 2 | 2025-10-21 |
| Recruiting | Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Ca Prostate Cancer (Adenocarcinoma) | Phase 3 | 2025-05-28 |
| Recruiting | Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in Patients With Advanced Head Advanced Head and Neck Cancer | Phase 3 | 2025-04-07 |
| Recruiting | LND101 for Fecal Microbiota Transplantation in Combination With Immune Checkpoint Blockade in Advanced Melanom Melanoma | Phase 2 | 2025-04-07 |
| Recruiting | Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy for Painful Non-Spine Bone Metastases Cancer Metastatic | Phase 3 | 2025-03-07 |
| Recruiting | Smartphone App-Based Mindfulness Intervention for French and English Speaker Cancer Survivors Cancer, Psychological | N/A | 2025-03-07 |
| Recruiting | Platinum and Taxane Chemo in Met Castration Resistant Prostate Cancer Patients With Alterations in DNA Damage Metastatic Castration-resistant Prostate Cancer, Metastatic Prostate Cancer | Phase 3 | 2024-12-30 |
| Recruiting | STRatIfication of Vulvar SCC by HPV and p53 Status to Guide Excision Vulvar Squamous Cell Carcinoma | N/A | 2024-12-10 |
| Recruiting | Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer Rectal Cancer | Phase 3 | 2024-06-26 |
| Recruiting | Androgen Suppression Combined With Nodal Irradiation and Dose Escalated Prostate Treatment Prostate Cancer | Phase 3 | 2024-04-25 |
| Recruiting | Paclitaxel and Ramucirumab +/- Zanidatamab in HER2 Postive Advanced Gastroesophageal Adenocarcinoma Gastroesophageal Adenocarcinoma | Phase 2 | 2024-04-16 |
| Recruiting | Fixed Duration vs Continuous Anti-CD38 Antibody Therapy Among Transplant Ineligible Older Adults With Newly-Di Multiple Myeloma | Phase 3 | 2024-04-10 |
| Recruiting | Ibrutinib Combination Therapy in Transplant Ineligible Individuals With Newly Diagnosed Primary CNS Lymphoma Non-hodgkin Lymphoma | Phase 2 | 2024-02-13 |
| Active Not Recruiting | Neoadjuvant Platform Trial in Non-Small Cell Lung Cancer NSCLC | Phase 2 | 2023-09-15 |
| Recruiting | Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cance Breast Cancer | Phase 2 | 2023-06-13 |
| Completed | RP-6306 in Patients With Advanced Cancer Advanced Cancer | Phase 2 | 2023-05-24 |
| Withdrawn | PembROlizumab With or Without Microbial EcOsystem ThErapeutic 4 (MET4) in Advanced Head and Neck Squamous Cell Advanced Head and Neck Squamous Cell Carcinoma | Phase 2 | 2023-05-12 |
| Recruiting | SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer Oropharyngeal Cancer | Phase 3 | 2023-02-10 |
| Recruiting | Economic Analysis of Early vs Delayed Therapy in Newly Diagnosed Asymptomatic High-Risk Patients With Chronic Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma | — | 2023-01-27 |
| Recruiting | Adjuvant Therapy in POLE-Mutated and p53-Wildtype/NSMP Early Stage Endometrial Cancer RAINBO BLUE & TAPER Endometrial Cancer | Phase 2 | 2022-12-19 |
| Recruiting | Pembrolizumab and Brentuximab Vedotin vs GDP and Stem Cell Transplant for Relapsed/Refractory Hodgkin Lymphoma Hodgkin Lymphoma | Phase 2 | 2022-11-01 |
| Recruiting | Immunotherapy Platform Study in Platinum Resistant High Grade Serous Ovarian Cancer Ovarian Cancer | Phase 2 | 2022-05-03 |
| Recruiting | Emotion and Symptom-Focused Engagement Trial for Individuals With Acute Leukemia Acute Leukemia | N/A | 2022-01-06 |
| Active Not Recruiting | 177 LuPSMA-617 vs Docetaxel in Metastatic Castration Resistant and PSMA-Positive Prostate Cancer Prostate Cancer | Phase 2 | 2021-08-11 |
| Active Not Recruiting | Fulvestrant and Ipatasertib for Advanced HER-2 Negative and Estrogen Receptor Positive (ER+) Breast Cancer Fol Breast Cancer | Phase 3 | 2021-01-27 |
| Completed | Immunization With IMM-101 vs Observation for Prevention of Respiratory and Severe COVID-19 Related Infections Cancer, Covid-19 | Phase 3 | 2020-10-01 |
| Recruiting | Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cel Lymphoma, B-Cell | EARLY_Phase 1 | 2020-09-02 |
| Active Not Recruiting | CFI-400945 and Durvalumab in Patients With Advanced Triple Negative Breast Cancer Breast Cancer | Phase 2 | 2020-08-10 |
| Recruiting | Study of CTDNA Response Adaptive Immuno-Chemotherapy in Lung Cancer Lung Cancer | Phase 2 / Phase 3 | 2020-05-26 |
| Recruiting | A Phase II Study of Durvalumab Treatment - Substudy A: In Patients Who Discontinued Prior Checkpoint Therapy D Cancer | Phase 2 | 2020-03-09 |
| Active Not Recruiting | Local Ablative Therapy For Hormone Sensitive Oligometastatic Prostate Cancer Prostate Cancer Metastatic | N/A | 2019-11-15 |
| Active Not Recruiting | Trimodality Therapy With/Out Durvalumab to Treat Patients With Muscle-Invasive Bladder Cancer Bladder Cancer | Phase 2 | 2019-10-25 |
| Active Not Recruiting | De-Escalation Radiotherapy in Patients With Low-Risk HPV-Related Oropharyngeal Squamous Cell Carcinoma Oropharyngeal Cancer | Phase 2 | 2019-06-28 |
| Terminated | Nivolumab Ipilimumab in Patients With hyperMutated Cancers Detected in Blood (NIMBLe) Advanced Solid Tumors | Phase 2 | 2019-03-11 |
| Active Not Recruiting | CFI-400945 in Patients With Advanced/Metastatic Breast Cancer Breast Cancer | Phase 2 | 2019-02-14 |
| Active Not Recruiting | CFI-402257 in Combination With Paclitaxel in Patients With Advanced/Metastatic HER2-Negative Breast Cancer Breast Cancer | Phase 1 / Phase 2 | 2019-02-05 |
| Recruiting | Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine Brain Metastases | Phase 3 | 2018-11-22 |
| Recruiting | Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer Breast Cancer | Phase 3 | 2018-10-16 |
| Active Not Recruiting | Prostate Cancer Biomarker Enrichment and Treatment Selection Prostate Cancer | Phase 2 | 2018-08-01 |
| Active Not Recruiting | ASA in Prevention of Ovarian Cancer (STICs and STONEs) Ovarian Cancer Prevention | Phase 2 | 2018-07-24 |
| Completed | NEO: Neoadjuvant Chemotherapy, Excision and Observation for Early Rectal Cancer Rectal Cancer | Phase 2 | 2018-06-29 |
| Active Not Recruiting | Cisplatin + Radiotherapy vs Durvalumab + Radiotherapy Followed by Durvalumab vs Durvalumab + Radiotherapy Foll Oropharyngeal Squamous Cell Carcinoma | Phase 2 | 2018-05-28 |
| Recruiting | Canadian Profiling and Targeted Agent Utilization Trial (CAPTUR) Lymphoma, Non-Hodgkin, Multiple Myeloma, Advanced Solid Tumors | Phase 2 | 2018-03-23 |
| Terminated | Concurrent Dabrafenib + Trametinib With Sterotactic Radiation in BRAF Mutation-Positive Malignant Melanoma and Melanoma, Brain Metastases | Phase 2 | 2018-02-09 |
| Active Not Recruiting | Palbociclib in Patients With Metastatic Castration-Resistant Prostate Cancer Prostate Cancer | Phase 2 | 2017-07-04 |
| Active Not Recruiting | Durvalumab and Tremelimumab ± Platinum-Based Chemotherapy in Patients With Metastatic Squamous or Non-Squamous Lung Cancer Metastatic | Phase 2 | 2017-03-28 |
| Active Not Recruiting | Phase II High Dose Brachytherapy and Low Dose Rate Brachytherapy as Monotherapy in Localized Prostate Cancer Prostate Carcinoma | N/A | 2017-03-06 |
| Terminated | Response to Pembrolizumab in Metastatic Melanoma: Computed Tomography Texture Analysis as a Predictive Biomark Metastatic Melanoma | Phase 2 | 2017-01-10 |
| Completed | mTORC1/mTORC2 Kinase Inhibitor AZD2014 in Previously Treated Glioblastoma Multiforme Glioblastoma Multiforme | Phase 1 | 2016-12-22 |
| Completed | Durvalumab With or Without Tremelimumab in Metastatic Castration Resistant Prostate Cancer Prostate Cancer | Phase 2 | 2016-12-15 |
| Completed | Durvalumab and Tremelimumab in Patients With Advanced Rare Tumours Advanced Rare Tumours | Phase 2 | 2016-12-14 |
| Completed | Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma Mesothelioma | Phase 2 / Phase 3 | 2016-11-11 |
| Completed | Gemcitabine and Nab-Paclitaxel vs Gemcitabine, Nab-Paclitaxel, Durvalumab and Tremelimumab as 1st Line Therapy Pancreatic Adenocarcinoma | Phase 2 | 2016-11-07 |
| Recruiting | Duration of Anti-PD-1 Therapy in Metastatic Melanoma Unresectable/Metastatic Melanoma | Phase 3 | 2016-10-31 |
| Completed | Durvalumab and Tremelimumab and Best Supportive Care vs Best Supportive Care in Patients With Advanced Colorec Colorectal Cancer | Phase 2 | 2016-10-12 |
| Completed | High-Dose Weekly Carfilzomib Plus Cyclophosphamide and Dexamethasone in the Treatment of Relapsed Multiple Mye Multiple Myeloma | Phase 2 | 2016-07-05 |
| Completed | A Phase I Study of CX5461 Cancer | Phase 1 | 2016-06-13 |
| Completed | Durvalumab in Patients With HER-2 Positive Metastatic Breast Cancer Receiving Trastuzumab Metastatic Breast Cancer | Phase 1 | 2016-05-17 |
| Completed | Two Different Schedules of Palbociclib + Second Line Endocrine Therapy in Estrogen Receptor Positive, HER2 Neg Breast Cancer | Phase 2 | 2016-04-08 |
| Completed | Study Comparing Stereotactic Body Radiotherapy vs Conventional Palliative Radiotherapy (CRT) for Spinal Metast Spinal Metastases | N/A | 2016-01-04 |
| Completed | Study of Palliative Radiotherapy for Symptomatic Hepatocellular Carcinoma and Liver Metastases Hepatocellular Carcinoma, Liver Metastases | N/A | 2015-12-11 |
| Active Not Recruiting | Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell Lymphoma Lymphoma | Phase 2 | 2015-10-27 |
| Active Not Recruiting | Durvalumab With or Without Tremelimumab in Advanced Incurable Solid Malignancies Given With or Without Standar Solid Malignancies | Phase 1 | 2015-10-16 |
| Completed | A Dose-Ranging Study of IPH2201 in Patients With Gynecologic Malignancies Gynecologic Cancer | Phase 1 | 2015-09-17 |
| Completed | Vinblastine and Temsirolimus in Pediatrics With Recurrent or Refractory Lymphoma or Solid Tumours Including CN Recurrent Lymphoma, Refractory Lymphoma, Solid Tumours | Phase 1 | 2015-06-24 |
| Completed | Selumetinib in Patients Receiving Pemetrexed and Platinum-based Chemotherapy in Advanced or Metastatic KRAS Wi Non-Small Cell Lung Cancer | Phase 2 | 2015-05-26 |
| Completed | Buparlisib in Patients With Relapsed and Refractory Chronic Lymphocytic Leukemia Chronic Lymphocytic Leukemia | Phase 2 | 2015-04-27 |
| Active Not Recruiting | Economic Analysis of Alliance A041202 CLL Study Chronic Lymphocytic Leukemia | — | 2015-04-15 |
| Active Not Recruiting | Double Blind Placebo Controlled Controlled Study of Adjuvant MEDI4736 In Completely Resected NSCLC Non-Small Cell Lung Cancer | Phase 3 | 2015-02-24 |
| Active Not Recruiting | MG1 Maraba/MAGE-A3, With and Without Adenovirus Vaccine With Transgenic MAGE-A3 Insertion in Incurable MAGE-A3 Advanced/Metastatic Solid Tumours | Phase 1 / Phase 2 | 2015-01-22 |
| Completed | Feasibility Trial Of Image Guided External Beam Radiotherapy With Or Without High Dose Rate Brachytherapy Boos Prostate Cancer | N/A | 2014-04-22 |
| Completed | Nab-Paclitaxel to Paclitaxel in Advanced Urothelial Cancer Progressing on or After Platinum Containing Regimen Urothelial Cancer | Phase 2 | 2014-03-11 |
| Completed | Romidepsin, Gemcitabine, Dexamethasone and Cisplatin in the Treatment of Peripheral T-Cell and Diffuse Large B Peripheral T-Cell Lymphoma, Diffuse Large B-Cell Lymphoma | Phase 1 | 2013-10-01 |
| Completed | Study of Selumetinib in Patients With Previously Treated or Untreated Advanced/Metastatic NSCLC Non Small Cell Lung Cancer | Phase 1 | 2013-06-04 |
| Completed | A Study of Reolysin For Patients With Advanced/Metastatic Breast Cancer Metastatic Breast Cancer | Phase 2 | 2013-02-20 |
| Completed | Reolysin Combined With Docetaxel and Prednisone or Docetaxel and Prednisone Alone in Metastatic Castration Res Prostate Cancer | Phase 2 | 2012-12-14 |
| Completed | Radical Versus Simple Hysterectomy and Pelvic Node Dissection With Low-risk Early Stage Cervical Cancer Cervical Cancer | N/A | 2012-12-10 |
| Completed | Reolysin in Previously Treated Advanced/Metastatic, Non Small Cell Lung Cancer Receiving Standard Salvage Ther Non Small Cell Lung Cancer | Phase 2 | 2012-12-10 |
| Completed | Reolysin in Combination With FOLFOX6 and Bevacizumab or FOLFOX6 and Bevacizumab Alone in Metastatic Colorectal Colorectal Cancer | Phase 2 | 2012-10-26 |
| Completed | P13Kinase Inhibitor BKM120 in Combination With Panitumumab in Metastatic/Advanced RAS-Wild Type Colorectal Can Metastatic Colorectal Cancer | Phase 1 / Phase 2 | 2012-09-06 |
| Active Not Recruiting | A Phase II Study of Sunitinib or Temsirolimus in Patients With Advanced Rare Tumours Advanced Rare Tumours | Phase 2 | 2012-02-09 |
| Completed | A Phase III Randomized Trial of Metformin vs Placebo in Early Stage Breast Cancer Breast Cancer | Phase 3 | 2010-08-13 |
| Completed | Intraperitoneal vs Intravenous Chemotherapy Following Neoadjuvant Chemotherapy in Ovarian Cancer Fallopian Tube Cancer, Metastatic Cancer, Ovarian Cancer | Phase 2 | 2010-03-03 |
| Active Not Recruiting | Health Education Materials With/Out a Physical Activity Program for Patients Who Have Undergone Treatment for Anxiety Disorder, Cognitive/Functional Effects, Colorectal Cancer | N/A | 2009-06-02 |
| Completed | Radiation Therapy With or Without Temozolomide in Treating Older Patients With Newly Diagnosed Glioblastoma Mu Brain and Central Nervous System Tumors | Phase 3 | 2007-11-14 |
| Completed | Letrozole in Breast Cancer Who Have Received 5 Years of Aromatase Inhibitor Therapy Breast Cancer | Phase 3 | 2004-11-23 |