| Not Yet Recruiting | A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events Coronary Atherosclerosis, Mixed Dyslipidemia, Hypercholesterolemia | Phase 3 | 2026-06-01 |
| Active Not Recruiting | A Study of Bempedoic Acid or Its Single-pill Combination Therapy With Ezetimibe in Patients With Primary Hyper Primary Hypercholesterolaemia, Mixed Dyslipidemia | — | 2026-03-03 |
| Recruiting | A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies Hematological Malignancies | Phase 1 / Phase 2 | 2026-01-16 |
| Completed | Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid / Ezetimibe, Healthy Subjects | Phase 1 | 2025-12-09 |
| Recruiting | A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostat Metastatic Castration-resistant Prostate Cancer | Phase 1 | 2025-12-03 |
| Recruiting | A Study of DS9051b in Participants With Advanced or Metastatic Adrenocortical Carcinoma and Metastatic Castrat Advanced or Metastatic Adrenocortical Carcinoma, Metastatic Castration-resistant Prostate Cancer | Phase 1 | 2025-11-04 |
| Completed | A Study Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Eze Healthy Subjects | Phase 1 | 2025-10-28 |
| Recruiting | Study of Trastuzumab Deruxtecan, Pembrolizumab, and Platinum-based Chemotherapy in First-line HER2 Overexpress Non-small Cell Lung Cancer | Phase 3 | 2025-10-24 |
| Recruiting | A Study of DS3610a in Participants With Advanced Solid Tumor Solid Tumors, Metastatic Solid Tumors | Phase 1 | 2025-10-09 |
| Completed | Evaluating Bioequivalence of a Fixed Dose Combination Versus Tablets of Bempedoic Acid / Ezetimibe and Rosuvas Healthy Subjects | Phase 1 | 2025-10-07 |
| Recruiting | A Study of DS5361b in Participants With Advanced Solid Tumors Advanced Solid Tumor | Phase 1 | 2025-10-02 |
| Recruiting | Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometri Endometrial Cancer | Phase 3 | 2025-09-30 |
| Completed | Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, Healthy Subjects | Phase 1 | 2025-09-29 |
| Recruiting | Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin Urothelial Cancer, Bladder Cancer | Phase 2 / Phase 3 | 2025-09-26 |
| Active Not Recruiting | Patterns of Care and Outcomes in Locally Recurrent Inoperable or Metastatic Triple-Negative Breast Cancer Triple Negative Breast Cancer | — | 2025-09-01 |
| Recruiting | Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Acute Myeloid Leukemia, Leukemia | Phase 2 | 2025-07-18 |
| Recruiting | A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors Recurrent or Metastatic Solid Tumors | Phase 1 | 2025-07-17 |
| Completed | Real-World Outcomes of Patients With Metastatic Breast Cancer After Treatment With First-Line ET+CDK4/6i Advanced/Metastatic HER2-negative Breast Cancer | — | 2025-04-14 |
| Completed | A Study to Investigate the Effectiveness and Safety of Bempedoic Acid in Patients With Primary Hypercholestero Primary Hypercholesterolemia or Mixed Hyperlipidemia | Phase 4 | 2025-04-01 |
| Recruiting | A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell C Esophageal Squamous Cell Carcinoma | Phase 3 | 2025-03-27 |
| Recruiting | Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in Ovarian Cancer | Phase 3 | 2025-03-19 |
| Recruiting | Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastric Cancer, Gastroesophageal Junction Cancer | Phase 3 | 2025-02-27 |
| Recruiting | Real-world Effectiveness and Safety of Trastuzumab Deruxtecan in Patients With Locally Advanced or Metastatic HER2-positive Gastric Cancer, HER2-positive Gastroesophageal Junction | — | 2025-02-27 |
| Recruiting | Clinical Effectiveness and Safety of Trastuzumab Deruxtecan (T-DXd) in Chinese Patients With HER2m NSCLC (RERU Non-small Cell Lung Cancer | — | 2025-02-21 |
| Completed | A Study to Investigate the Prevalence of Human Epidermal Growth Factor Receptor 2 (HER2) Immunohistochemistry Cervical Cancers, Endometrial Cancer, Ovarian Cancer | — | 2025-01-31 |
| Active Not Recruiting | A Study to Evaluate the Safety and Effectiveness of Mirogabalin in Chinese Adult Patients With Diabetic Periph Diabetic Peripheral Neuropathic Pain | — | 2025-01-24 |
| Completed | Real-world Outcomes of Patients With HER2+ Metastatic Breast Cancer After Treatment With Trastuzumab Deruxteca HER2-positive Breast Cancer | — | 2025-01-20 |
| Recruiting | A Study of Raludotatug Deruxtecan in Participants With Advanced/Metastatic Solid Tumors (REJOICE-PanTumor01) Advanced Solid Tumor, Metastatic Solid Tumors | Phase 2 | 2025-01-06 |
| Recruiting | Quizartinib or Placebo Plus Chemotherapy in Newly Diagnosed Patients With FLT3-ITD Negative AML Leukemia | Phase 3 | 2024-11-19 |
| Recruiting | First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors Solid Tumors, Sarcoma | Phase 1 | 2024-11-14 |
| Recruiting | A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Act Non-small Cell Lung Cancer, Lung Cancer | Phase 1 / Phase 2 | 2024-10-30 |
| Completed | Study to Assess the Effect of a CYP3A Weak Inducer Rufinamide on Quizartinib Pharmacokinetics in Healthy Subje Healthy Subjects | Phase 1 | 2024-10-29 |
| Completed | A Study to Evaluate QTc Prolongation With Quizartinib in Healthy Subjects Under Rapid Acceleration of Heart Ra Healthy Subjects | Phase 1 | 2024-10-24 |
| Recruiting | Assessment of Quizartinib Pharmacokinetic in Subjects With Severe Hepatic Impairment Hepatic Impairment | Phase 1 | 2024-09-30 |
| Completed | Real-World Pharmacological Treatment Pattern of Neuropathic Pain in China Diabetic Peripheral Neuropathic Pain, Chemotherapy-induced Peripheral Neuropathy, Neuropathic Pain | — | 2024-08-16 |
| Completed | A Study of Real-world Treatment Patterns and Outcomes in Chinese Advanced NSCLC Patients Who Previously Receiv Non-small Cell Lung Cancer (NSCLC) | — | 2024-08-15 |
| Completed | A Study of Treatment Patterns in HER2-positive Unresectable and Advanced Gastric/ Gastroesophageal Junction Ca Gastric Cancer, Gastroesophageal Junction Cancer | — | 2024-08-15 |
| Recruiting | A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maint Extensive Stage-small Cell Lung Cancer | Phase 1 / Phase 2 | 2024-07-22 |
| Completed | A Study Assessing Risk Factors for Oral Mucositis/Stomatitis and Ocular Surface Events in NSCLC and Breast Can Advanced/Metastatic NSCLC, Advanced/Metastatic HER2-negative Breast Cancer | — | 2024-07-09 |
| Recruiting | A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell L Small Cell Lung Cancer | Phase 3 | 2024-05-21 |
| Recruiting | A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Met Recurrent or Metastatic Solid Tumors | Phase 2 | 2024-04-10 |
| Completed | Study on Prevalence and Impact of Brain Metastases on Survival in Lung Cancer by Line of Treatment Non-small Cell Lung Cancer, Lung Cancer, Metastatic Cancer | — | 2024-03-01 |
| Recruiting | A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Per Solid Cancer | Phase 2 / Phase 3 | 2024-02-27 |
| Recruiting | A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors Advanced Solid Tumor, Melanoma, Head and Neck Cancer | Phase 2 | 2024-02-26 |
| Recruiting | A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors Advanced Solid Tumor | Phase 1 | 2024-02-16 |
| Recruiting | A Study to Assess the Effectiveness of Trastuzumab Deruxtecan in Chinese Breast Cancer Patients (REFRESH) HER2-positive Breast Cancer, HER2-low Breast Cancer, Breast Cancer | — | 2024-01-15 |
| Recruiting | A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s) Advanced Cancer, Metastatic Cancer | Phase 3 | 2024-01-05 |
| Recruiting | Trastuzumab Deruxtecan (T-DXd) in Patients Who Have Hormone Receptor-negative and Hormone Receptor-positive HE Breast Cancer | Phase 3 | 2023-12-30 |
| Terminated | A Study to Explore Safety, Pharmacokinetics, and Early Clinical Signal of Efficacy of DS-2325a in Patients Wit Netherton Syndrome | Phase 1 / Phase 2 | 2023-09-28 |
| Recruiting | First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors Advanced Solid Tumor, Metastatic Solid Tumor | Phase 1 / Phase 2 | 2023-08-18 |
| Completed | Study of Predictors of Clinical Outcomes in Patients With HR+ and HER2-low/Negative Breast Cancer Hormone-receptor-positive Breast Cancer, HER2-low Breast Cancer, HER2-negative Breast Cancer | — | 2023-07-31 |
| Completed | A Study of DS-7011a in Patients With Systemic Lupus Erythematosus Systemic Lupus Erythematosus | Phase 1 / Phase 2 | 2023-06-07 |
| Active Not Recruiting | A Study of DS-1103a Combination Therapy in Participants With Advanced Solid Tumors Advanced Solid Tumor, Breast Cancer | Phase 1 | 2023-05-30 |
| Completed | A Study to Describe the Real-world Treatment Patterns and Associated Outcomes in Patients of China With HER2-p HER2-positive Breast Cancer | — | 2023-03-15 |
| Completed | A Study to Evaluate Effectiveness and Safety of Edoxaban in Patients 80 Years of Age or Older With Nonvalvular Atrial Fibrillation | — | 2023-02-16 |
| Active Not Recruiting | Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Metastatic Non Small Cell Lung Cancer | Phase 3 | 2023-01-11 |
| Completed | A Study of Prevalence of HER3 Expression in Non-Small Cell Lung Cancer Non-small Cell Lung Cancer | — | 2022-12-19 |
| Completed | EUropean Real-world Experience Of Previously Treated Advanced/Metastatic HER2-positive Breast Cancer Patients HER2-positive Breast Cancer | — | 2022-11-11 |
| Completed | A Study to Assess the Safety and Pharmacokinetics of Multiple Ascending Subcutaneous Doses of DS-2325a in Heal Netherton Syndrome | Phase 1 | 2022-11-08 |
| Completed | A Study of DS-1211b in Individuals With PseudoXanthoma Elasticum Pseudoxanthoma Elasticum | Phase 2 | 2022-10-20 |
| Completed | A Dose Finding Study of VN-0200 Respiratory Syncytial Virus Infections | Phase 2 | 2022-10-13 |
| Completed | A Study to Evaluate the Efficacy and Safety of Sitafloxacin in Adult Subjects With Acute Exacerbation of Chron COPD Exacerbation Acute | Phase 4 | 2022-08-10 |
| Active Not Recruiting | HERTHENA-Lung02: A Study of Patritumab Deruxtecan Versus Platinum-based Chemotherapy in Metastatic or Locally Nonsquamous Non-small Cell Lung Cancer, EGFR L858R, EGFR Exon 19 Deletion | Phase 3 | 2022-07-08 |
| Completed | A Study to Assess the Safety and Pharmacokinetics of Single Ascending Subcutaneous and Intravenous Doses of DS Netherton Syndrome | Phase 1 | 2022-06-20 |
| Terminated | A Study of DS-9606a in Patients With Advanced Solid Tumors Advanced Cancer, Metastatic Cancer, Germ Cell Tumor | Phase 1 | 2022-05-31 |
| Active Not Recruiting | Ifinatamab Deruxtecan (I-DXd) in Subjects With Pretreated Extensive-Stage Small Cell Lung Cancer (ES-SCLC) Extensive-stage Small-cell Lung Cancer | Phase 2 | 2022-03-09 |
| Recruiting | Study of Dato-DXd Plus Pembrolizumab vs Pembrolizumab Alone in the First-line Treatment of Subjects With Advan Metastatic Non Small Cell Lung Cancer | Phase 3 | 2022-03-04 |
| Completed | A Study of a Single Ascending Dose Study of DS-7011a in Healthy Subjects Systemic Lupus Erythematosus | Phase 1 | 2022-02-02 |
| Completed | Pseudoxanthoma Elasticum (PXE) Natural History Biomarkers in PXE Individuals and Their Biological Non-PXE Sibl Pseudoxanthoma Elasticum | — | 2021-08-30 |
| Completed | An Observational Study Investigating the Change in Blood Cholesterol With Mevalotin® Tablet Administration in Dyslipidemia | — | 2021-08-10 |
| Active Not Recruiting | HER3-DXd (Patritumab Deruxtecan; U3-1402) in Combination With Osimertinib in Subjects With Locally Advanced or Non-Small Cell Lung Cancer (NSCLC) | Phase 1 | 2021-06-11 |
| Active Not Recruiting | Valemetostat Tosylate (DS-3201b), an Enhancer of Zeste Homolog (EZH) 1/2 Dual Inhibitor, for Relapsed/Refracto Relapsed/Refractory Peripheral T-Cell Lymphoma, Adult T Cell Leukemia/Lymphoma | Phase 2 | 2021-06-03 |
| Active Not Recruiting | Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarci Gastric Cancer, Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma | Phase 3 | 2021-05-21 |
| Completed | A Study to Determine the Absolute Oral Bioavailability of Quizartinib Using a Radiolabeled Microtracer in Heal Healthy Subjects | Phase 1 | 2021-04-26 |
| Completed | Study of DS-1062a in Advanced or Metastatic Non-small Cell Lung Cancer With Actionable Genomic Alterations (TR Non-small Cell Lung Cancer | Phase 2 | 2021-03-30 |
| Completed | Trastuzumab Deruxtecan in Participants With HER2-mutated Metastatic Non-small Cell Lung Cancer (NSCLC) Non-Small Cell Lung Cancer | Phase 2 | 2021-03-19 |
| Completed | Trastuzumab Deruxtecan in Participants With HER2-overexpressing Advanced or Metastatic Colorectal Cancer Advanced Colorectal Cancer | Phase 2 | 2021-03-05 |
| Completed | Real-world Study on Edoxaban Treatment for Patients With Non-valvular Atrial Fibrillation in China Non-valvular Atrial Fibrillation | — | 2021-02-26 |
| Active Not Recruiting | HERTHENA-Lung01: Patritumab Deruxtecan in Subjects With Metastatic or Locally Advanced EGFR-mutated Non-Small Non-Small Cell Lung Cancer Metastatic, Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor | Phase 2 | 2021-02-02 |
| Recruiting | A Long-term Study Evaluating Hepatotoxicity Associated With TURALIO™ (Pexidartinib) Treatment Hepatotoxicity, Tenosynovial Giant Cell Tumor | — | 2021-01-07 |
| Active Not Recruiting | A Study of DS-6000a in Subjects With Advanced Renal Cell Carcinoma and Ovarian Tumors Renal Cell Carcinoma, Ovarian Tumor | Phase 1 | 2020-12-22 |
| Active Not Recruiting | Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer Wit Non-small Cell Lung Cancer | Phase 3 | 2020-12-21 |
| Active Not Recruiting | A Study of Trastuzumab Deruxtecan (T-DXd) Versus Trastuzumab Emtansine (T-DM1) in High-risk HER2-positive Part HER2-Positive Primary Breast Cancer, Residual Invasive Breast Cancer | Phase 3 | 2020-12-04 |
| Completed | Study to Evaluate Discontinuation and Re-Treatment in Participants With Tenosynovial Giant Cell Tumor (TGCT) P Tenosynovial Giant Cell Tumor | Phase 4 | 2020-10-20 |
| Active Not Recruiting | A Study Evaluating DS-1055a in Participants With Relapsed or Refractory Locally Advanced or Metastatic Solid T Solid Tumor, Advanced Cancer, Metastatic Solid Tumor | Phase 1 | 2020-10-09 |
| Completed | A Study of Quizartinib Pharmacokinetics in Participants With Moderate Hepatic Impairment Hepatic Impairment, Moderate Impaired Hepatic Function | Phase 1 | 2020-09-22 |
| Active Not Recruiting | Datopotamab Deruxtecan (Dato-DXd) in Combination With Pembrolizumab With or Without Platinum Chemotherapy in S Advanced or Metastatic NSCLC | Phase 1 | 2020-09-15 |
| Terminated | A Study to Evaluate U3-1402 in Subjects With Advanced or Metastatic Colorectal Cancer Metastatic Colorectal Cancer | Phase 2 | 2020-09-14 |
| Completed | Edoxaban in Patients With Non-valvular Atrial Fibrillation Undergoing Percutaneous Coronary Intervention Non-valvular Atrial Fibrillation | — | 2020-06-30 |
| Terminated | DS-6157a in Participants With Advanced Gastrointestinal Stromal Tumor (GIST) Gastrointestinal Stromal Tumors | Phase 1 | 2020-05-08 |
| Active Not Recruiting | DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cance Breast Cancer, Non-small Cell Lung Carcinoma | Phase 1 | 2020-02-10 |
| Completed | Study of Pexidartinib in Participants With Moderate Hepatic Impairment Compared With Healthy Participants Moderate Hepatic Impairment | EARLY_Phase 1 | 2020-01-07 |
| Completed | DS-8201a in HER2-positive Gastric Cancer That Cannot Be Surgically Removed or Has Spread (DESTINY-Gastric02) Adenocarcinoma Gastric Stage IV With Metastases, Adenocarcinoma - GEJ | Phase 2 | 2019-11-26 |
| Completed | Study of Single-dose DS-3201b in Participants With Hepatic Impairment Hepatic Impairment | Phase 1 | 2019-11-21 |
| Recruiting | Study of Ifinatamab Deruxtecan (DS-7300a, I-DXd) in Participants With Advanced Solid Malignant Tumors Advanced Solid Tumor, Malignant Solid Tumor | Phase 1 / Phase 2 | 2019-11-03 |
| Terminated | DS-1205c With Osimertinib for Metastatic or Unresectable Epidermal Growth Factor Receptor (EGFR)-Mutant Non-Sm Non-small Cell Lung Cancer (NSCLC) | Phase 1 | 2019-04-10 |
| Completed | Effect of Low-Fat Food on Pexidartinib Pharmacokinetics in Healthy Volunteers Healthy Volunteers | Phase 1 | 2019-04-01 |
| Active Not Recruiting | Trastuzumab Deruxtecan (DS-8201a) Versus Investigator's Choice for HER2-low Breast Cancer That Has Spread or C Breast Cancer | Phase 3 | 2018-12-27 |
| Terminated | Milademetan Plus Quizartinib Combination Study in FLT3-ITD Mutant Acute Myeloid Leukemia (AML) Acute Myeloid Leukemia | Phase 1 | 2018-12-12 |
| Completed | Food Effects on Milademetan Pharmacokinetics in Healthy Participants Food Effects on Pharmacokinetics | EARLY_Phase 1 | 2018-08-16 |
| Active Not Recruiting | Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of Acute Myeloid Leukemia | Phase 1 / Phase 2 | 2018-08-15 |
| Active Not Recruiting | DS-8201a Versus T-DM1 for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive, Unresectable and/or Metast Breast Cancer | Phase 3 | 2018-08-09 |
| Completed | Trastuzumab Deruxtecan With Nivolumab in Advanced Breast and Urothelial Cancer Breast Cancer, Urothelial Carcinoma | Phase 1 | 2018-08-02 |
| Completed | DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02] Breast Cancer | Phase 3 | 2018-08-01 |
| Completed | Pharmacokinetics (PK) Drug Interaction Study of Milademetan and Itraconazole or Posaconazole in Healthy Partic Pharmacokinetics | EARLY_Phase 1 | 2018-07-13 |
| Terminated | DS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing or -Mutated Non-Small Cell Lung Cancer Non-Small Cell Lung Cancer | Phase 2 | 2018-05-21 |
| Completed | Edoxaban for Prevention of Blood Vessels Being Blocked by Clots (Thrombotic Events) in Children at Risk Becaus Cardiac Disease | Phase 3 | 2018-05-15 |
| Completed | Effect of Pexidartinib on the Way the Body Processes CYP3A4 and CYP2C9 Substrates (Pharmacokinetics) Drug Interaction Potential | Phase 1 | 2018-02-26 |
| Withdrawn | DS-9231 in Intermediate-risk (Sub-massive) Acute Pulmonary Embolism (PE) Pulmonary Embolism | Phase 2 | 2018-01-01 |
| Active Not Recruiting | U3-1402 in Metastatic or Unresectable Non-Small Cell Lung Cancer Non-Small Cell Lung Cancer (NSCLC) | Phase 1 | 2017-10-30 |
| Completed | Baseline Epidemiologic Assessment of Abuse-Deterrence of MorphaBond Extended Release (BEAD-MB) Baseline Epidemiologic Assessment | — | 2017-10-16 |
| Terminated | A Study of DS-8201a in Metastatic Breast Cancer Previously Treated With Trastuzumab Emtansine (T-DM1) Breast Cancer | Phase 2 | 2017-08-25 |
| Completed | DS2330b Alone and With Sevelamer in Patients on Chronic Hemodialysis Hyperphosphatemia | Phase 1 | 2017-08-17 |
| Terminated | DS-3201b for Acute Myelogenous Leukemia (AML) or Acute Lymphocytic Leukemia (ALL) Leukemia, Myeloid, Acute, Leukemia, Lymphocytic, Acute | Phase 1 | 2017-04-05 |
| Completed | Edoxaban Treatment in Routine Clinical Practice in Patients With Venous Thromboembolism in Korea and Taiwan (E Venous Thromboembolism | — | 2017-03-27 |
| Completed | Hokusai Study in Pediatric Patients With Confirmed Venous Thromboembolism (VTE) Venous Thromboembolism (VTE), Pulmonary Embolism, Deep Vein Thrombosis (DVT) | Phase 3 | 2017-03-27 |
| Completed | Edoxaban Compared to Standard Care After Heart Valve Replacement Using a Catheter in Patients With Atrial Fibr Atrial Fibrillation | Phase 3 | 2017-03-21 |
| Completed | Effect of Probenecid on Pexidartinib Pharmacokinetics Pharmacokinetics in Healthy Volunteers | Phase 1 | 2017-02-27 |
| Completed | Edoxaban Treatment in Routine Clinical Practice for Patients With Atrial Fibrillation in Korea and Taiwan (ETN Atrial Fibrillation | — | 2017-02-21 |
| Completed | Comparison of Two Doses of Edoxaban Using Different Tests (Assays) and Clinical Outcomes Atrial Fibrillation | N/A | 2017-01-24 |
| Active Not Recruiting | Study of DS-1001b in Patients With Gene IDH1-Mutated Gliomas Glioma | Phase 1 | 2017-01-19 |
| Terminated | Antibody DS-8273a Administered in Combination With Nivolumab in Subjects With Advanced Colorectal Cancer Colorectal Neoplasm | Phase 1 | 2016-12-01 |
| Completed | Tenosynovial Giant Cell Tumors (TGCT) Observational Platform Project Giant Cell Tumors | — | 2016-11-18 |
| Completed | Edoxaban Management in Diagnostic and Therapeutic Procedures Atrial Fibrillation, Venous Thromboembolism | — | 2016-11-01 |
| Completed | Quizartinib With Standard of Care Chemotherapy and as Continuation Therapy in Patients With Newly Diagnosed FL Acute Myeloid Leukemia, Leukemia | Phase 3 | 2016-09-01 |
| Completed | Study to Assess the Safety, Pharmacokinetics/Dynamics of DS-1040b in Subjects With Acute Submassive Pulmonary Pulmonary Embolism, Thrombotic Disease | Phase 1 / Phase 2 | 2016-06-23 |
| Completed | A Study Assessing the Mass Balance of a Single Oral Dose of [14C] DS-8500a in Healthy Subjects Pharmacokinetics | Phase 1 | 2016-05-01 |
| Completed | A Study to Determine the Effects of Itraconazole on the Pharmacokinetics (PK) of DS-8500 in Healthy Subjects Pharmacokinetics | Phase 1 | 2016-05-01 |
| Terminated | An Open Study Assessing the Safety and Tolerability of U3-1784 Advanced Solid Tumors, Hepatocellular Cancer (HCC) | Phase 1 | 2016-02-29 |
| Completed | Study of the Effects of Ethnicity on the Pharmacokinetics, Pharmacodynamics and Safety of DS-1040b Healthy | Phase 1 | 2016-02-01 |
| Withdrawn | Study to Evaluate the Efficacy and Safety of DS-1971a for the Treatment of Diabetic Peripheral Neuropathic Pai Neuropathic Pain, Diabetes | Phase 2 | 2016-02-01 |
| Completed | An Observational Study Investigating the Effectiveness of Pravastatin on Renal Function in Korean Dyslipidemic Dyslipidemia Associated With Type II Diabetes Mellitus | — | 2016-01-20 |
| Completed | 12-Week Study of DS-8500a in Subjects With Type 2 Diabetes Mellitus on Metformin Type 2 Diabetes Mellitus | Phase 2 | 2016-01-01 |
| Terminated | Patritumab With Cetuximab and a Platinum Agent for Squamous Cell Carcinoma (Cancer) of the Head and Neck (SCCH Head and Neck Neoplasms | Phase 2 | 2015-12-22 |
| Completed | Phase 1 Study to Evaluate the Safety and Tolerability of DS-1040b IV Infusion With Clopidogrel in Healthy Subj Drug Interaction | Phase 1 | 2015-12-01 |
| Completed | The Effect of CS-3150 Exposure on Corrected QT (QTc) Interval Duration in Healthy Volunteers Hypertension, Mineralocorticoid Receptor Antagonist | Phase 1 | 2015-11-19 |
| Completed | Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040b in Subjects With Acute Ischemic Acute Ischemic Stroke, Thrombotic Disease | Phase 1 / Phase 2 | 2015-09-01 |
| Completed | Multiple Dose Study of D1971a in Healthy Volunteers Healthy | Phase 1 | 2015-09-01 |
| Completed | Edoxaban Treatment in Routine Clinical Practice for Patients With Non Valvular Atrial Fibrillation Atrial Fibrillation | — | 2015-08-01 |
| Completed | Cancer Venous Thromboembolism (VTE) Venous Thromboembolism (VTE), Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE) | Phase 3 | 2015-07-16 |
| Terminated | A Combination Clinical Study of PLX3397 and Pembrolizumab To Treat Advanced Melanoma and Other Solid Tumors Melanoma, Non-small Cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck | Phase 1 / Phase 2 | 2015-07-02 |
| Completed | Study of DS-7080a for the Treatment of Macular Degeneration Neovascular Age-Related Macular Degeneration, Diabetic Macular Edema | Phase 1 | 2015-07-01 |
| Completed | Safety Study of DS-5565 for Treatment of Fibromyalgia Pain in Subjects With Chronic Kidney Disease Fibromyalgia | Phase 3 | 2015-06-26 |
| Completed | Effect of Repeated Doses of DS-8500a on Pharmacokinetics of Rosuvastatin in Healthy Volunteers Drug Pharmacokinetics in Healthy Volunteers | Phase 1 | 2015-05-12 |
| Completed | Phase 3 Study of Pexidartinib for Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sh Pigmented Villonodular Synovitis, Giant Cell Tumors of the Tendon Sheath, Tenosynovial Giant Cell Tumor | Phase 3 | 2015-05-11 |
| Completed | A PHASE 1, OPEN-LABEL, CROSS-OVER, FIXED SEQUENCE STUDY TO EVALUATE THE EFFECT OF MULTIPLE DOSES OF DS-1971A O Healthy | Phase 1 | 2015-05-01 |
| Completed | A Phase 2 Exploratory Study of CS-3150 in Japanese Hypertensive Patients With Moderate Renal Impairment Hypertension | Phase 2 | 2015-05-01 |
| Completed | An Open-Label Extension Study of DS-5565 for 52 Weeks in Pain Associated With Fibromyalgia Pain Associated With Fibromyalgia | Phase 3 | 2015-02-04 |
| Completed | Treatment of Pain Associated With Fibromyalgia Pain Associated With Fibromyalgia | Phase 3 | 2015-01-16 |
| Completed | A Study to Evaluate Efficacy and Safety of CS-3150 in Japanese Type 2 Diabetic Subjects With Microalbuminuria Diabetic Nephropathy | Phase 2 | 2015-01-01 |
| Completed | A Study to Evaluate Efficacy and Safety of CS-3150 in Japanese Hypertensive Subjects Essential Hypertension | Phase 2 | 2015-01-01 |
| Completed | Patritumab With Cetuximab and a Platinum Containing Therapy for Patients With Head and Neck Cancer Squamous Cell Carcinoma of the Head and Neck | Phase 1 | 2014-12-01 |
| Terminated | Safety, Tolerability and Pharmacokinetics of Milademetan Alone and With 5-Azacitidine (AZA) in Acute Myelogeno Acute Myelogenous Leukemia, Myelodysplastic Syndrome | Phase 1 | 2014-11-25 |
| Completed | Phase 1 Pediatric Pharmacokinetics/Pharmacodynamics (PK/PD) Study Deep Vein Thrombosis, Venous Thromboembolism | Phase 1 | 2014-11-05 |
| Completed | Relative Bioavailability DS-1971a Suspension and Tablets and Food Effect on DS-1971a Tablets Healthy | Phase 1 | 2014-11-01 |
| Completed | Pilot PK/PD Study of DS-1093a in Patients With Chronic Kidney Disease Chronic Renal Disease, Renal Anemia | Phase 1 | 2014-11-01 |
| Completed | Treatment of Pain Associated With Fibromyalgia Pain Associated With Fibromyalgia | Phase 3 | 2014-11-01 |
| Completed | Treatment of Pain Associated With Fibromyalgia Pain Associated With Fibromyalgia | Phase 3 | 2014-10-27 |
| Completed | Effects of Age, Gender & Race on the Pharmacokinetics (PK)of DS-1971a Healthy | Phase 1 | 2014-09-01 |
| Withdrawn | Efficacy, Safety, Tolerability and Pharmacokinetics of SUN13837 to Treat Acute Stroke Stroke | Phase 2 | 2014-09-01 |
| Completed | Multiple Dose Study of DS-1971a Healthy | Phase 1 | 2014-07-01 |
| Completed | Multiple Ascending Dose Study of DS-1093 in Healthy Subjects Anaemia | Phase 1 | 2014-05-01 |
| Completed | (QuANTUM-R): An Open-label Study of Quizartinib Monotherapy vs. Salvage Chemotherapy in Acute Myeloid Leukemia AML | Phase 3 | 2014-05-01 |
| Completed | Pharmacokinetics of Tivantinib in Subjects With Advanced Solid Tumors and Hepatic Impairment Hepatic Impairment, Solid Tumor, Cancer | Phase 1 | 2014-04-01 |
| Completed | Edoxaban vs. Warfarin in Subjects Undergoing Cardioversion of Nonvalvular Atrial Fibrillation (NVAF) Atrial Fibrillation | Phase 3 | 2014-03-25 |
| Completed | Single Ascending Dose Study Using DS-1971 to Assess Safety, Tolerability, and Pharmacokinetics in Healthy Part Safety, Tolerability, Pharmacokinetics | Phase 1 | 2014-03-01 |
| Terminated | Study of Patritumab in Combination With Erlotinib in Subjects With Locally Advanced or Metastatic Non-Small-Ce Lung Cancer, Non-small Cell Lung Cancer | Phase 3 | 2014-03-01 |
| Completed | Open-label Study of DS-8273a to Assess Its Safety and Tolerability, and Assess Its Pharmacokinetic and Pharmac Advanced Solid Tumor, Lymphoma | Phase 1 | 2014-02-01 |
| Completed | DS1040b/Aspirin Drug/Drug Interaction Study Acute Ischemic Stroke | Phase 1 | 2014-01-01 |
| Terminated | A Phase 1b Open Label, Dose Escalation Study of PLX3397 in Combination With Vemurafenib in V600-mutated BRAF M V600-mutated BRAF Unresectable Melanoma, V600-mutated BRAF Metastatic Melanoma, Stage III or Stage IV Metastatic Melanoma That Has Not Been Previously Treated With a Selective BRAF Inhibitor | Phase 1 | 2013-11-05 |
| Completed | AMG 162 (Denosumab) Phase 3 Study (DESIRABLE Study) in Participants With Rheumatoid Arthritis on Disease-modif Rheumatoid Arthritis | N/A | 2013-10-01 |
| Completed | A Two-part Study in Edoxaban-treated Healthy Subjects to Establish a Punch Biopsy Bleeding Model and to Evalua Bleeding | Phase 1 | 2013-10-01 |
| Completed | Study to Assess the Safety, Pharmacokinetics and Pharmacodynamics of DS-1150b in Healthy Subjects and Subjects Type 2 Diabetes Mellitus | Phase 1 | 2013-09-01 |
| Completed | Randomized, Placebo-controlled, 2 Period, Single-blind, Sequential, Multiple Ascending Dose Study Type 2 Diabetes Mellitus | Phase 1 | 2013-09-01 |
| Completed | A Phase 1b/2 Study of PLX3397 + Radiation Therapy + Temozolomide in Patients With Newly Diagnosed Glioblastoma Patients With Newly Diagnosed Glioblastoma | Phase 1 / Phase 2 | 2013-07-18 |
| Completed | A Multiple Ascending Dose Study of Milademetan in Subjects With Advanced Solid Tumors or Lymphomas Advanced Solid Tumor, Lymphoma | Phase 1 | 2013-07-11 |
| Completed | Study to Assess Pharmacokinetics, Immunogenicity and Safety/Tolerability of Patritumab (U3-1287) Solid Tumors | Phase 1 | 2013-06-01 |
| Completed | Edoxaban in Peripheral Arterial Disease Peripheral Arterial Disease | Phase 2 | 2013-02-06 |
| Completed | Study of Tivantinib in Subjects With Inoperable Hepatocellular Carcinoma (HCC) Who Have Been Treated With One Hepatocellular Carcinoma | Phase 3 | 2012-12-27 |
| Completed | Study to Evaluate the Efficacy, Safety and Pharmacokinetics of ASB17061 Capsules in Adult Subjects With Atopic Atopic Dermatitis | Phase 2 | 2012-11-28 |
| Completed | Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of SUN13837 Injection in Adult Subjects With Acut Acute Spinal Cord Injury | Phase 2 | 2012-08-08 |
| Completed | A Randomized, Open-Label, Parallel-Group, Multi-Center Study for the Evaluation of Efficacy and Safety of Edox Deep Vein Thrombosis, Venous Thrombosis | Phase 2 | 2012-08-01 |
| Completed | Effect of Tivantinib on the QTC Interval in Cancer Subjects Solid Tumors | Phase 1 | 2012-07-01 |
| Terminated | Pilot Study of PLX3397 in Patients With Advanced Castration-Resistant Prostate Cancer (CRPC) Prostate Cancer | Phase 2 | 2012-05-25 |
| Completed | Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors Solid Tumors | Phase 1 | 2012-05-01 |
| Completed | A Open-Label, Multiple Ascending Dose Study of DS-3078a, an Oral TORC1/2 Kinase Inhibitor, in Subjects With Ad Advanced Solid Tumor, Lymphoma | Phase 1 | 2012-04-01 |
| Completed | Open Label Study to Evaluate Safety and Efficacy of 2 Doses of Quizartinib in Patients With Relapsed or Refrac Leukemia, Myeloid, Acute | Phase 2 | 2012-04-01 |
| Completed | A Study of AC220 Given After Transplant in Subjects With Acute Myeloid Leukemia (AML) Leukemia, Myeloid, Acute | Phase 1 | 2012-04-01 |
| Completed | Pharmacodynamic Evaluation of Switching From Ticagrelor to Prasugrel in Subjects With Stable Coronary Artery D Coronary Artery Disease | Phase 4 | 2012-03-01 |
| Completed | Observational Study to Evaluate the Simplified-STroke REhabilitation Assessment of Movement (S-STREAM) Scale i Nonhemorrhagic Ischemic Stroke, Motor Function | — | 2012-01-18 |
| Terminated | A Phase 2 Study of PLX3397 in Patients With Recurrent Glioblastoma Recurrent Glioblastoma | Phase 2 | 2011-12-03 |
| Completed | Drug-drug Interaction Study of Tivantinib (ARQ 197) With Omeprazole, S-warfarin, Caffeine, Midazolam, and Digo Solid Tumors | Phase 1 | 2011-12-01 |
| Completed | Treatment of Neuropathic Pain Associated With Diabetic Peripheral Neuropathy Diabetic Peripheral Neuropathy | Phase 2 | 2011-11-28 |
| Completed | Phase 1/2 Safety and Efficacy of PLX3397 in Adults With Relapsed or Refractory Acute Myeloid Leukemia (AML) Acute Myeloid Leukemia | Phase 1 / Phase 2 | 2011-11-21 |
| Terminated | Phase 1b/2 Study of U3-1287 in Combination With Trastuzumab Plus Paclitaxel in Newly Diagnosed Metastatic Brea Metastatic Breast Cancer | Phase 1 / Phase 2 | 2011-11-01 |
| Completed | A Study to Assess AC220 Given in Combination With Induction and Consolidation Therapy in Newly Diagnosed Acute Leukemia, Myeloid, Acute | Phase 1 | 2011-10-01 |
| Completed | Safety and Tolerability of DS-7423 in Subjects With Advanced Solid Malignant Tumors Solid Tumor, Colorectal Cancer, Endometrial Cancer | Phase 1 | 2011-07-01 |
| Completed | A Two-Part, Single Ascending Dose Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynam Type 2 Diabetes Mellitus | Phase 1 | 2011-04-01 |
| Terminated | A Study of DS-2248 in Participants With Advanced Solid Tumors Solid Tumors, Non-small Cell Lung Carcinoma | Phase 1 | 2011-03-29 |
| Completed | Safety and Efficacy Study of PLX3397 in Adults With Relapsed or Refractory Hodgkin Lymphoma Hodgkin Lymphoma | Phase 2 | 2011-03-03 |
| Completed | Colesevelam for Children With Type 2 Diabetes Type 2 Diabetes Mellitus | Phase 4 | 2011-02-24 |
| Terminated | Tivantinib Plus Erlotinib Versus Placebo Plus Erlotinib for the Treatment of Non-squamous, Non-small-cell Lung Non Squamous, Non-small-cell Lung Cancer | Phase 3 | 2011-01-11 |
| Completed | Study to Assess the Safety and Tolerability of U3-1565 in Subjects With Advanced Solid Malignant Tumors Advanced Solid Malignant Tumors, Advanced Ovarian Cancer | Phase 1 | 2011-01-01 |
| Completed | The Influence of Smoking Status on Prasugrel and Clopidogrel Treated Subjects Taking Aspirin and Having Stable Coronary Artery Disease | Phase 4 | 2010-11-01 |
| Completed | Study to Assess Safety, Tolerability, and Pharmacokinetics of Oral Doses for AC430 in Healthy Subjects Rheumatoid Arthritis | Phase 1 | 2010-11-01 |
| Withdrawn | Safety Study for Intravenous (IV) AC480 (AC480IV) to Treat Advanced Solid Tumors Solid Tumors | Phase 1 | 2010-11-01 |
| Completed | Study of Erlotinib With or Without Investigational Drug (U3-1287) in Subjects With Advanced Non-small Cell Lun NSCLC (Advanced Non-small Cell Lung Cancer) | Phase 1 / Phase 2 | 2010-09-01 |
| Completed | CS1008- in Combination With Sorafenib Compared to Sorafenib Alone in Subjects With Advanced Liver Cancer Advanced Hepatocellular Carcinoma, Liver Cancer, Hepatic Cancer | Phase 2 | 2010-07-09 |
| Completed | Determination of the Relative Bioavailability of ARQ 197 Tablet Formulation With Capsule C Formulation as a Re Solid Tumors | Phase 1 | 2010-07-01 |
| Completed | Study of CS-1008 in Combination With FOLFIRI in Patients Who Have Failed Other Treatments Metastatic Colorectal Cancer | Phase 1 | 2010-05-01 |
| Completed | Study of Erlotinib With or Without Investigational Drug (CS-7017) in Subjects With Advanced Non-small Cell Lun Advanced Non-small Cell Lung Cancer (NSCLC) | Phase 2 | 2010-03-01 |
| Terminated | ARQ 197 for Participants With Relapsed or Refractory Germ Cell Tumors Non-CNS Germ Cell Tumors (Seminomas and Nonseminomas) | Phase 2 | 2010-02-02 |
| Completed | Prasugrel/Clopidogrel Maintenance Dose Washout Study Coronary Artery Disease | Phase 4 | 2010-02-01 |
| Completed | ARQ 197 in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer Metastatic Colorectal Cancer | Phase 1 / Phase 2 | 2010-01-26 |
| Completed | Dose Finding, Safety and Tolerability Study for AC220 to Treat Advanced Solid Tumors Solid Tumors | Phase 1 | 2010-01-01 |
| Completed | Efficacy Study for AC220 to Treat Acute Myeloid Leukemia (AML) Acute Myeloid Leukemia | Phase 2 | 2009-11-01 |
| Completed | Combination Chemotherapy With CS-1008 to Treat Ovarian Cancer Ovarian Cancer Stage IIIC, Ovarian Cancer Stage IV | Phase 2 | 2009-10-06 |
| Completed | Safety Study of PLX108-01 in Patients With Solid Tumors Solid Tumor | Phase 1 | 2009-10-01 |
| Completed | Comparative Investigation of Low Molecular Weight (LMW) Heparin/Edoxaban Tosylate (DU176b) Versus (LMW) Hepari Venous Thromboembolism, Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE) | Phase 3 | 2009-10-01 |
| Completed | Study of CS-7017 in Combination With FOLFIRI in Subjects With Metastatic Colorectal Cancer Who Failed First-Li Colorectal Cancer, Neoplasms, Colorectal | Phase 2 | 2009-09-01 |
| Completed | Olmesartan Comparison to Losartan in Hypertensive Subjects Hypertension | Phase 4 | 2009-08-01 |
| Terminated | Study of CS-7017 in Colorectal Cancer Patients Who Have Achieved Disease Control Following First-Line Chemothe Colorectal Cancer | Phase 2 | 2009-07-31 |
| Terminated | CS-1008 Used With Irinotecan Versus Irinotecan Alone in Subjects With Metastatic Colorectal Carcinoma Who Fail Metastatic Colorectal Cancer | Phase 2 | 2009-07-01 |
| Completed | CS-1008 With Carboplatin/Paclitaxel in Chemotherapy naïve Subjects With Metastatic or Unresectable Non-small C Non-small Cell Lung Cancer | Phase 2 | 2009-06-01 |
| Completed | Parallel-Group Comparison of Olmesartan (OLM), Amlodipine (AML) and Hydrochlorothiazid (HCTZ) in Hypertension Essential Hypertension | Phase 3 | 2009-06-01 |
| Completed | Colesevelam as Add-on to Pioglitazone Therapy for Type 2 Diabetes Mellitus Type 2 Diabetes Mellitus | Phase 3 | 2009-04-01 |
| Completed | Hydrochlorothiazide as add-on to Olmesartan/Amlodipine in Hypertension Essential Hypertension | Phase 3 | 2009-04-01 |
| Completed | Extended Use Protocol for Participants With Cancer to Receive Continued Treatment With CS-7017 Advanced Cancer | Phase 1 | 2009-03-01 |
| Completed | Welchol as Monotherapy for Type 2 Diabetes Mellitus Type 2 Diabetes Mellitus | Phase 3 | 2009-01-01 |
| Completed | Study of Carboplatin/Paclitaxel With or Without Investigational Drug (CS-7017) in Subjects With Metastatic Non Metastatic Non-small Cell Lung Cancer | Phase 2 | 2008-12-01 |
| Terminated | Effects of Multiple Doses of CS-8080 in Healthy Volunteers Healthy | Phase 1 | 2008-11-01 |
| Completed | Global Study to Assess the Safety and Effectiveness of Edoxaban (DU-176b) vs Standard Practice of Dosing With Stroke, Atrial Fibrillation, Embolism | Phase 3 | 2008-11-01 |
| Completed | A Dose Escalation Study of a Combination Antihypertensive Drug in the Treatment of Various Groups of Patients Hypertension | Phase 4 | 2008-11-01 |
| Completed | A Multicenter, Randomized, Placebo-Controlled, Double-Blind Study of SUN13834 in Adult Subjects With Atopic De Atopic Dermatitis | Phase 2 | 2008-07-16 |
| Completed | SUN11031 in Cachexia Associated With Chronic Obstructive Pulmonary Disease (COPD) Cachexia | Phase 2 | 2008-05-15 |
| Completed | Safety and Efficacy Study of a Triple Combination Therapy in Subjects With Hypertension Hypertension | Phase 3 | 2008-05-01 |
| Completed | 18 Week Study Evaluating Safety and Efficacy of Olmesartan, Amlodipine, and Hydrochlorothiazide, in Type 2 Dia Type 2 Diabetes, Hypertension | Phase 4 | 2008-05-01 |
| Completed | 12-week Safety Evaluation of Oral CS-0777 in Multiple Sclerosis Patients Multiple Sclerosis | Phase 1 | 2008-03-01 |
| Completed | Effects of CS-8080 in Healthy Volunteers Healthy | Phase 1 | 2008-01-01 |
| Terminated | A Phase 1/2 Study of CS7017, an Oral PPARγ Agonist, in Combination With Paclitaxel Anaplastic Thyroid Cancer | Phase 1 / Phase 2 | 2008-01-01 |
| Terminated | Randomized, Double-blind, Active-controlled, Study of Rivoglitazone in Type 2 Diabetes Mellitus Type 2 Diabetes Mellitus | Phase 3 | 2007-11-14 |
| Completed | Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, Type 2 Diabetes Mellitus, Hypercholesterolemia, Pre-diabetes | Phase 3 | 2007-11-01 |
| Completed | Blood Pressure Lowering Ability and Safety of an Olmesartan and Amlodipine Based Treatment Regimen in Patients Hypertension | Phase 3 | 2007-09-01 |
| Completed | Open-label Study of CS-1008 for Subjects With Untreated and Unresectable Pancreatic Cancer Pancreatic Cancer | Phase 2 | 2007-08-15 |
| Completed | Preliminary Study of Piclozotan in Patients With Motor Complications Associated With Parkinson's Disease Parkinson's Disease | Phase 2 | 2007-07-13 |
| Completed | A Study to Assess the Safety of a Potential New Drug in Comparison to the Standard Practice of Dosing With War Atrial Fibrillation, Thromboembolism | Phase 2 | 2007-06-01 |
| Completed | Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabet Type 2 Diabetes, Hyperlipidemia | Phase 3 | 2007-05-01 |
| Completed | Study of Rivoglitazone in Type 2 Diabetes Mellitus Type 2 Diabetes Mellitus | Phase 3 | 2007-04-23 |
| Completed | Combination of Olmesartan and Hydrochlorothiazide in Essential Hypertension Essential Hypertension | Phase 3 | 2007-02-01 |
| Completed | Use of the Combination of Olmesartan and Hydrochlorothiazide in Essential Hypertension Essential Hypertension | Phase 3 | 2007-02-01 |
| Completed | A Phase I Study of AC220 in Patients With Relapsed/Refractory Acute Myeloid Leukemia Regardless of FLT3 Status Acute Myeloid Leukemia, Leukemia, Myelodysplastic Syndrome | Phase 1 | 2007-01-01 |
| Completed | An Examination of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Elderly Patients W Hypertension | Phase 4 | 2006-12-01 |
| Completed | A Study of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Stage I and Stage II Hype Hypertension | Phase 4 | 2006-12-01 |
| Completed | An Examination of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Patients With Type Hypertension | Phase 4 | 2006-11-01 |
| Completed | Study of an Experimental New Drug, PPARγ Agonist Taken by Mouth by Participants With Advanced or Metastatic Ca Neoplasm | Phase 1 | 2006-11-01 |
| Completed | Efficacy and Safety of Olmesartan Medoxomil in Stage 1 and 2 Essential Hypertension Essential Hypertension | Phase 4 | 2006-08-01 |
| Completed | Evaluation of the Additional Efficacy, and Safety of Olmesartan Medoxomil 20mg / Hydrochlorothiazide 12.5mg in Essential Hypertension | Phase 3 | 2006-08-01 |
| Completed | A Study of DU-176b in Preventing Blood Clots After Hip Replacement Surgery Thrombosis, Hip Replacement | Phase 2 | 2006-05-01 |
| Completed | Effects on Colesevelam HC1 (WelChol®) on Insulin Sensitivity in Subjects With Type 2 Diabetes Mellitus Type 2 Diabetes Mellitus | Phase 2 | 2006-05-01 |
| Completed | Evaluation of Glucose Lowering Effect, Safety and Tolerability of CS-917 Diabetes Mellitus, Type 2 | Phase 2 | 2006-01-01 |
| Completed | Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High Cholesterol Hypercholesterolemia | Phase 4 | 2005-11-01 |
| Completed | Olmesartan Pediatric Pharmacokinetic (PK) Study Hypertension | Phase 1 | 2005-09-01 |
| Completed | Treatment of High Blood Pressure Using Olmesartan With Hydrochlorothiazide Compared to an ACE Inhibitor With a Hypertension | Phase 4 | 2005-09-01 |
| Completed | Effects of Colesevelam on How the Body Responds to Insulin in Patients With Type 2 Diabetes Type 2 Diabetes | Phase 2 | 2005-06-01 |
| Completed | Assessment of Efficacy and Safety of Olmesartan Medoxomil in Children and Adolescent Patients With High Blood Hypertension | Phase 2 / Phase 3 | 2005-05-01 |
| Completed | Study of Co-administration of Olmesartan Medoxomil Plus Amlodipine in Patients With Mild to Severe Hypertensio Hypertension | Phase 3 | 2005-05-01 |
| Completed | Effect of Combination Therapy With Two Drugs (Colesevelam and Ezetimibe) in Patients With High Cholesterol Hypercholesterolemia | Phase 4 | 2005-03-01 |
| Completed | Study of the Efficacy and Safety of DU-176b in Preventing Blood Clots in Patients Undergoing Total Hip Replace Arthroplasty, Replacement, Hip, Thrombosis | Phase 2 | 2005-01-01 |
| Terminated | The Efficacy Study of Sodium Hyaluronate to Treat Symptomatic Hip Osteoarthritis Symptomatic Hip Osteoarthritis | Phase 3 | 2005-01-01 |
| Completed | Long-Term Study of Safety and Efficacy of WelChol® as an Additional Therapy in Patients With Type 2 Diabetes Type 2 Diabetes | Phase 3 | 2004-12-01 |
| Completed | Placebo and Active Controlled Study of Rivoglitazone in Type 2 Diabetes Type 2 Diabetes | Phase 2 / Phase 3 | 2004-12-01 |
| Completed | The Relative Effects of Olmesartan Medoxomil, Irbesartan and Valsartan on the Activity of the Blood Pressure C Healthy | Phase 4 | 2004-11-01 |
| Terminated | Efficacy of SUN N4057 in Subjects With Acute Ischemic Stroke and Measurable Penumbra on Magnetic Resonance Ima Stroke | Phase 2 | 2004-09-01 |
| Completed | Olmesartan Medoxomil Versus Losartan Potassium in Patients With Mild to Moderate Essential Hypertension Essential Hypertension | Phase 3 | 2004-08-01 |
| Completed | WelChol® and Sulfonylurea in Treating Patients With Type 2 Diabetes Type 2 Diabetes | Phase 3 | 2004-06-01 |
| Completed | WelChol® With Metformin in Treating Patients With Type 2 Diabetes Type 2 Diabetes | Phase 3 | 2004-06-01 |
| Completed | WelChol® and Insulin in Treating Patients With Type 2 Diabetes Type 2 Diabetes | Phase 3 | 2004-06-01 |
| Completed | An Examination of the Safety and Blood Pressure Lowering Effect of Increasing Doses of Benicar® and Benicar® H Hypertension | Phase 4 | 2004-03-01 |
| Terminated | Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Carotid Artery Di Atherosclerosis, Heterozygous Familial Hypercholesterolemia | Phase 2 / Phase 3 | 2004-02-01 |
| Completed | DJ-927 as Second-Line Therapy in Treating Patients With Progressive Locally Advanced or Metastatic Colorectal Colorectal Cancer | Phase 2 | 2004-02-01 |
| Completed | DJ-927 and Capecitabine in Treating Patients With Locally Advanced or Metastatic Solid Tumors Unspecified Adult Solid Tumor, Protocol Specific | Phase 1 | 2004-02-01 |
| Completed | A Comparison of the Effect of Olmesartan Medoxomil, Losartan Potassium, and Atenolol on the Ability of Overwei Hypertension, Insulin Resistance, Metabolic Syndrome | Phase 4 | 2004-02-01 |
| Completed | Evaluation of the Effects of Carperitide in Patients With Congestive Heart Failure Heart Failure, Congestive, Heart Decompensation, Left Ventricular Failure | Phase 2 | 2004-01-01 |
| Completed | Soblidotin in Treating Patients With Progressive Locally Advanced or Metastatic Non-Small Cell Lung Cancer Lung Cancer | Phase 2 | 2003-04-01 |
| Completed | Soblidotin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma Sarcoma | Phase 2 | 2003-04-01 |
| Completed | Study to Compare Welchol and TriCor to TriCor Alone in Patients With High Cholesterol Hypercholesterolemia, Hyperlipidemia, Familial Combined | Phase 4 | 2003-02-01 |
| Completed | Exatecan Mesylate in Treating Patients With Ewing's Sarcoma, Primitive Neuroectodermal Tumor, or Desmoplastic Sarcoma | Phase 2 | 2003-01-01 |
| Completed | Exatecan Mesylate in Treating Children With Relapsed or Refractory Rhabdomyosarcoma Sarcoma | Phase 2 | 2003-01-01 |
| Completed | A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Pravastatin Hypercholesterolemia | Phase 4 | 2002-11-01 |
| Completed | Vascular Improvement With Olmesartan Medoxomil Study Hypertension | Phase 4 | 2002-11-01 |
| Completed | A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Atorvastati Hypercholesterolemia | Phase 4 | 2002-11-01 |
| Completed | Efficacy and Safety of the ACAT Inhibitor CS-505 (Pactimibe) for Reducing the Progression of Coronary Artery D Coronary Heart Disease | Phase 2 | 2002-11-01 |
| Completed | Safety and Efficacy of Floxin Otic Solution in the Treatment of Acute Otitis Media in Children Otitis Media | Phase 3 | 2002-11-01 |
| Completed | A Study to Determine the Effect of WelChol Tablets on Cholesterol in Patients Who Have Been Taking Simvastatin Hypercholesterolemia | Phase 4 | 2002-11-01 |
| Completed | Olmesartan Medoxomil Versus Losartan in Patients With Hypertension Essential Hypertension | Phase 3 | 2002-05-01 |
| Completed | Gemcitabine With or Without Exatecan Mesylate in Treating Patients With Locally Advanced or Metastatic Pancrea Pancreatic Cancer | Phase 3 | 2001-07-01 |
| Completed | Cevimeline in Treating Patients With Dry Mouth Caused by Radiation Therapy for Head and Neck Cancer Head and Neck Cancer, Oral Complications, Radiation Toxicity | Phase 3 | 2001-06-01 |
| Completed | DX-8951f in Treating Patients With Metastatic Stomach Cancer Esophageal Cancer, Gastric Cancer | Phase 2 | 2001-04-01 |
| Completed | A Randomized, Double Blind Study To Compare The Effects Of Olmesartan Medoxomil Versus Placebo In Patients Wit Atherosclerosis | Phase 3 | 2000-06-01 |
| Completed | DX-8951f in Treating Patients With Biliary Cancer Extrahepatic Bile Duct Cancer, Gallbladder Cancer, Liver Cancer | Phase 2 | 2000-03-01 |
| Completed | DX-8951f in Treating Women Who Have Advanced or Recurrent Cancer of the Cervix Cervical Cancer | Phase 2 | 2000-01-01 |
| Completed | DX-8951f in Treating Patients With Liver Cancer Liver Cancer | Phase 2 | 1999-09-01 |
| Completed | DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas Brain and Central Nervous System Tumors, Lymphoma, Unspecified Childhood Solid Tumor, Protocol Specific | Phase 1 | 1999-09-01 |
| Completed | Chemotherapy in Treating Patients With Recurrent, Metastatic, or Unresectable Ovarian, Fallopian Tube, or Peri Fallopian Tube Cancer, Ovarian Cancer, Primary Peritoneal Cavity Cancer | Phase 2 | 1999-07-01 |
| Completed | Chemotherapy in Treating Women With Metastatic Breast Cancer Breast Cancer | Phase 2 | 1999-06-01 |
| Completed | DX-8951f in Treating Patients With Metastatic Cancer of the Pancreas Pancreatic Cancer | Phase 2 | 1999-06-01 |
| Completed | Chemotherapy in Treating Patients Who Have Hematologic Cancer Leukemia, Myelodysplastic Syndromes | Phase 1 | 1999-06-01 |
| Completed | Chemotherapy in Treating Patients With Prostate Cancer Prostate Cancer | Phase 2 | 1999-06-01 |
| No Longer Available | Expanded Treatment Protocol for Adults With FLT3-ITD Mutated Relapsed or Refractory Acute Myeloid Leukemia (AM Acute Myeloid Leukemia With Gene Mutations | — | — |
| Approved For Marketing | Medical Access Program for Datopotamab Deruxtecan in EGFRm NSCLC Patients EGFRm Advanced Non-Small Cell Lung Cancer, EGFRm Metastatic Non-Small Cell Lung Cancer | — | — |
| No Longer Available | Medical Access Program for Patritumab Deruxtecan Epidermal Growth Factor Receptor (EGFR)-Mutated Non Small Cell Lung Cancer | — | — |
| Temporarily Not Available | Medical Access Program for Ifinatamab Deruxtecan in 3L+ Pretreated Extensive-stage Small Cell Lung Cancer SCLC, Extensive-stage Small Cell Lung Cancer | — | — |
| Completed | Study of CS-1008 in Patients With Advanced Solid Malignancies and Lymphomas (Without Leukemic Component) Malignancies, Lymphoma | Phase 1 | — |