Clinical Trials Directory

Trials / Completed

CompletedNCT00145574

Efficacy and Safety of Colesevelam in Pediatric Patients With Genetic High Cholesterol

Randomized, Double-blind, Placebo-controlled Efficacy and Safety Study of Colesevelam HCl Administered to Pediatric Patients With Heterozygous Familial Hypercholesterolemia on a Stable Dose of Statins or Treatment Naive to Lipid-lowering Therapy

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
194 (actual)
Sponsor
Daiichi Sankyo · Industry
Sex
All
Age
10 Years – 17 Years
Healthy volunteers
Not accepted

Summary

This study will evaluate the lipid-lowering effect and safety of colesevelam therapy administered to heterozygous familial pediatric patients 10 through 17 years of age who are on a stable dose of a pediatric-approved statin monotherapy (atorvastatin, lovastatin, simvastatin or pravastatin), or who are treatment naive to lipid-lowering therapy.

Conditions

Interventions

TypeNameDescription
DRUGcolesevelam HClTablets
DRUGplaceboMatching Tablets

Timeline

Start date
2005-11-01
Primary completion
2007-12-01
Completion
2007-12-01
First posted
2005-09-05
Last updated
2010-04-15
Results posted
2010-01-26

Locations

25 sites across 8 countries: United States, Australia, Austria, Canada, Israel, Netherlands, Norway, South Africa

Source: ClinicalTrials.gov record NCT00145574. Inclusion in this directory is not an endorsement.