Clinical Trials Directory

Trials / Sponsors / Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Academic / Other · 575 registered clinical trials72 currently recruiting.

StatusTrialPhaseStarted
Not Yet RecruitingRuxolitinib for Immune Effector Cell Associated Hemophagocytic Lymphohistiocytosis-like Syndrome (RISE)
Immune Effector Associated Hemophagocytic Lymphohistiocytosis-like Syndrome (IEC-HS)
Phase 12026-05-01
Not Yet RecruitingTotal Pancreatectomy With Islet Autotransplantation (TPIAT) for High-Risk Patients With Pancreatic Tumors
Periampullary Neoplasms, Pancreatic Cancer
N/A2026-05-01
RecruitingDK222 Study at Hopkins
Non-Small Cell Lung Cancer, Urothelial Cancer
Phase 12026-05-01
Not Yet RecruitingAssessing Administration of pBI-11 Via Electroporation for the Treatment of Patients With HPV16/18+
HPV Infection
Phase 22026-05-01
Not Yet RecruitingA DNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Glutamine Antagonist DRP-104, Nivolumab, and Ipili
Liver Cancer (Fibrolamellar Hepatocellular Cancer (FLC))
Phase 12026-05-01
Not Yet RecruitingPrecision Radiotherapy Enabled by Molecular MRI
Brain Cancer
N/A2026-04-01
Not Yet RecruitingCapecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced
Colorectal Cancer
Phase 22026-04-01
Not Yet RecruitingMusic Therapy in Newly Diagnosed Glioblastoma After Chemoradiation Therapy (MELODY-GBM)
Feasibility Studies
N/A2026-04-01
RecruitingMomelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloprolife
Chronic Myelomonocytic Leukemia, Myelodysplastic Syndromes, Myeloproliferative Overlap Neoplasms
EARLY_Phase 12026-03-19
RecruitingSupraphysiologic Testosterone Priming Induces Darolutamide Extended Response
Metastatic Castration-resistant Prostate Cancer
Phase 22026-03-09
RecruitingNeoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatme
Head and Neck Cancer, Squamous Cell Carcinoma, Oral Cavity Cancer
Phase 22026-03-04
RecruitingPhysician- and Patient-based Barriers to NGS Testing
Metastatic Prostate Cancer
N/A2026-01-06
WithdrawnBiopsy Collection for Men Undergoing Brachytherapy for Prostate Cancer
Prostate Cancer
2026-01-01
RecruitingPatient Navigation Program to Improve Clinical Trial Enrollment in Cancer Patients
Prostate Cancer, Kidney Cancer
N/A2025-12-01
RecruitingPediatric Radiation Therapy Registry
Sarcoma, Pediatric Brain Tumors
2025-10-31
RecruitingExercise in Prostate Cancer
Prostate Cancer Metastatic, Prostate Cancer
N/A2025-10-16
WithdrawnPSMA Therapy and Immunotherapy in Kidney Cancer
Metastatic Renal Cell Carcinoma, Metastatic Clear Cell Renal Cell Carcinoma
Phase 1 / Phase 22025-10-01
RecruitingA Clinical Trial to Assess PVX7 Immunotherapy Regimens in Advanced Cervical Cancer Patients
Cervical Cancer
Phase 12025-09-22
RecruitingNC410 and FOLFIRINOX in Combination With Nivolumab With or Without Ipilimumab in Patients With Untreated Metas
Pancreatic Cancer
Phase 22025-09-04
RecruitingThe COSMYC Trial (COmbined Suppression of MYC)
Metastatic Castration-resistant Prostate Cancer
Phase 22025-08-19
RecruitingKRAS-Targeted Vaccine Combined With Balstilimab and Botensilimab for Patients With Stage IV MMR-p Colorectal C
Colorectal Cancer, Pancreatic Cancer
Phase 12025-06-24
Recruiting7-Days Water-Only Fasting Trial in Prostate Cancer
Metastatic Prostate Cancer
N/A2025-06-03
RecruitingComparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectabl
Pancreatic Cancer
Phase 1 / Phase 22025-05-27
RecruitingTargeting Driver Oncogenes With a Peptide Vaccine Plus Durvalumab and Tremelimumab for Patients With Biliary T
Biliary Tract Cancers
Phase 12025-05-27
RecruitingProton SBRT for Spinal Metastasis
Spinal Metastasis
N/A2025-04-22
RecruitingA Trial to Evaluate CSF ctDNA and Safety of Plixorafenib Alone or With Retifanlimab in Patients With BRAF-alte
BRAF V600E Mutation
EARLY_Phase 12025-04-07
RecruitingStandard-of-Care Reduced-Intensity Conditioning (RIC) With 200 Versus 400 cGy of Total Body Irradiation (TBI)
Acute Leukemia, Acute Lymphoblastic Lymphoma
N/A2025-03-27
RecruitingTargeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma
Metastatic Sarcoma, Radiation Therapy Patient, Ewing Sarcoma
N/A2025-03-25
RecruitingStereotactic Body Proton Therapy for Treatment of Primary Renal Cell Carcinoma
Renal Cell Carcinoma
Phase 22025-02-25
RecruitingTrial Targeting Gut Bacterial Androgen Production to Reverse Therapeutic Resistance to Abiraterone in Patients
Prostate Cancer (Adenocarcinoma), Metastatic Prostate Cancer
Phase 22025-02-13
Terminated177Lu-PSMA (177Lu-PNT2002) in PSMA-Positive Adenoid Cystic Carcinoma
Adenoid Cystic Carcinoma
Phase 22025-02-10
RecruitingStudy of Senaparib in Combination With Temozolomide in ARID1A Mutation Associated Ovarian Cancer
Ovary Cancer, Fallopian Tube Cancer, Primary Peritoneal Cavity Cancer
Phase 22025-02-06
RecruitingSPECT Imaging for Pharmacokinetics and dosimEtry Towards TREATment Optimization
Prostate Cancer, Advanced Cancer
2025-02-03
RecruitingRenal Retention in High Grade Upper Tract Urothelial Cancer
High Grade Urothelial Carcinoma, Bladder Cancer, Urothelial Carcinoma Bladder
Phase 22024-11-25
RecruitingStudy in Patients With Breast Cancer Leptomeningeal Metastasis
Leptomeningeal Metastasis of Breast Cancer
2024-11-25
WithdrawnBrachytherapy Innovations in Gynecologic Cancer
Gynecologic Cancer
2024-10-01
RecruitingDarzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral
Hematologic Malignancy, Bone Marrow Transplant Rejection, Acute Myeloid Leukemia (AML)
EARLY_Phase 12024-09-19
RecruitingGut Microbiome, Adverse Effects, and Markers Through MEtabolic Reprogramming
Breast Cancer, Early-stage Breast Cancer
N/A2024-08-08
RecruitingPerioperative Gemcitabine, Cisplatin, and Pembrolizumab in Potentially Resectable Biliary Tract Cancers
Billiary Track Cancer
Phase 22024-07-08
RecruitingBehavioral Weight Loss for Cancer Survivors in Maryland: A Trial With Adaptive Interventions
Weight Loss
N/A2024-06-17
RecruitingExploration of Personalized Biomarkers During Neoadjuvant Radiation Therapy for Spinal and Sacral Chordoma
Chordoma of Spine, Chordoma of Skull Base, Chordoma of Sacrum
2024-06-14
RecruitingCemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorect
Colorectal Cancer
Phase 22024-06-13
TerminatedSurgical Resection of Synchronous Pulmonary or Hepatic Oligometastatic Pancreatic Ductal Adenocarcinoma
Pancreatic Ductal Adenocarcinoma, Oligometastatic Disease
N/A2024-05-21
RecruitingPeptide Vaccine To Prevent Acquired Resistance In Patients With Advanced ALK+ NSCLC
NSCLC Stage IV, ALK Fusion Protein Expression
Phase 1 / Phase 22024-05-13
RecruitingPET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC
Triple Negative Breast Cancer
Phase 22024-05-01
RecruitingPre-operative Hypofractionated Proton Therapy
Soft Tissue Sarcoma
N/A2024-04-18
RecruitingTrial of Neoadjuvant Enoblituzumab vs SOC in Men With High-Risk Localized Prostate Cancer
Prostate Cancer
Phase 22024-02-16
RecruitingDRP-104 (Glutamine Antagonist) in Combination With Durvalumab in Patients With Advanced Stage Fibrolamellar Ca
Fibrolamellar Hepatocellular Carcinoma
Phase 1 / Phase 22024-02-12
WithdrawnA Neoadjuvant Study of Abiraterone Acetate, Leuprolide Acetate, and Belzutifan in Men With Regional Prostate C
Prostate Cancer
Phase 22024-01-01
RecruitingNeoadjuvant Pembrolizumab and IO102-103 for Squamous Cell Carcinoma of the Head and Neck (SCCHN).
Head and Neck Squamous Cell Carcinoma
Phase 22023-12-14
WithdrawnRole of Pharyngeal High Resolution Manometry and Impedance in Swallow Function of Head and Neck Cancer Patient
Head and Neck Cancer, Dysphagia
N/A2023-12-01
Active Not RecruitingTagraxofusp-erzs, an IL-3 Diphtheria Fusion Protein, in Combination With Gemtuzumab Ozogamicin in Patients Wit
Acute Myeloid Leukemia
Phase 12023-11-20
Enrolling By InvitationClinical Trial Assessing the Safety and Immunologic Correlates of Heterologous Prime-Boost With pNGVL4a-Sig/E7
HPV 16 Infection, HPV-Related Carcinoma, Recurrence
Phase 12023-10-18
Active Not RecruitingSafety and Efficacy of Allogeneic HPV-specific T Cells in Adults With Recurrent or Metastatic HPV16+ Cancers
HPV 16+ Recurrent or Metastatic Cancer
Phase 1 / Phase 22023-10-18
RecruitingDifluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prosta
Prostate Cancer
Phase 22023-10-04
RecruitingImage-guided Focal Brachytherapy Utilizing Combined 18F-DCFPyl PET/CT
Prostate Cancer
EARLY_Phase 12023-08-03
Active Not RecruitingItacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients
Leukemia, Acute, Myelodysplastic Syndromes, Myelomonocytic Leukemia, Chronic
Phase 12023-07-06
TerminatedPhase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate Cancer
Prostate Cancer, Castration-resistant Prostate Cancer
Phase 22023-06-30
RecruitingCognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients
Brain Tumor, Head and Neck Cancer
N/A2023-05-17
WithdrawnNeoantigen-Targeted Vaccine Combined With Anti-PD-1 Antibody for Patients With Stage IV MMR-p Colon and Pancre
Pancreatic Cancer Metastatic, Colorectal Cancer Metastatic
Phase 12023-05-03
WithdrawnNeoadjuvant KRAS G12C Directed Therapy With Adagrasib (MRTX849) With or Without Nivolumab
Resectable Non-Small Cell Lung Cancer
Phase 22023-03-21
Withdrawn6 Months Adjuvant Temozolomide (TMZ) vs No Adjuvant TMZ in Newly Diagnosed MGMT Methylated Glioblastoma (GBM)
MGMT-Methylated Glioblastoma
2023-03-01
RecruitingLiquid Biopsy-informed Precision Oncology Study to Evaluate Utility of Plasma Genomic Profiling for Therapy Se
Solid Tumor
2023-01-27
WithdrawnNeoadjuvant Short-course Hypofractionated PBT for Non-metastatic RPS
Retroperitoneal Sarcoma
Phase 22022-12-01
TerminatedRIC alloBMT With Post-transplant Cyclophosphamide for Refractory Systemic Sclerosis
Systemic Sclerosis
Phase 12022-11-18
RecruitingKRAS-Targeted Vaccine With Chemoimmunotherapy, Nivolumab and Ipilimumab for Patients With NSCLC
Non-Small Cell Lung Cancer
Phase 12022-11-01
CompletedPost-transplant Flotetuzumab for AML
Leukemia, Myeloid, Acute
Phase 12022-10-20
TerminatedSMART-ER: Symptom Monitoring With Patient-reported Outcomes
Breast Cancer
N/A2022-10-03
RecruitingCarmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With Gli
Glioblastoma Multiforme
Phase 12022-08-31
Active Not RecruitingStudy of CRS-207, Pembrolizumab, Ipilimumab, and Tadalafil in Metastatic Pancreatic Cancer
Pancreatic Cancer
Phase 22022-08-22
RecruitingAtezolizumab Plus Etoposide and Platinum in Small Cell Bladder Cancer
Small Cell Neuroendocrine Carcinoma of Bladder, Bladder Cancer, Urothelial Carcinoma Bladder
Phase 22022-06-27
TerminatedPhase II Trial of Venetoclax and Rituximab as Initial Therapy in Older Patients With Mantle Cell Lymphoma
Mantle Cell Lymphoma
Phase 22022-06-21
RecruitingCardiometabolic Screening Program
Breast Cancer, Early-stage Breast Cancer
N/A2022-06-03
RecruitingIntraoperative Radiation Therapy After Stereotactic Body Radiation Therapy and Chemotherapy in Treatment of Pa
Pancreatic Cancer
Phase 12022-05-06
RecruitingBipolar Androgen Therapy (BAT) and Radium-223 (RAD) in Metastatic Castration-resistant Prostate Cancer (mCRPC)
Prostate Adenocarcinoma, Metastatic Prostate Adenocarcinoma, Castration-resistant
Phase 22022-04-28
RecruitingMutant KRAS -Targeted Long Peptide Vaccine for Patients at High Risk of Developing Pancreatic Cancer
High Risk Cancer, Pancreatic Cancer
Phase 12022-04-11
Active Not RecruitingProton Pencil Beam Scanning GRID for Treatment of Bulky Tumors
Sarcoma, Melanoma
N/A2022-04-06
CompletedSafety and Efficacy of Oral Testosterone Undecanoate Followed by Enzalutamide as Therapy for Men With Metastat
Prostate Cancer, Castration-resistant Prostate Cancer, Metastatic Castration-resistant Prostate Cancer
Phase 22022-03-07
TerminatedCombined Aerobic and Resistance Exercise Training in Metastatic Renal Cell Carcinoma
Renal Cell Carcinoma Metastatic
N/A2022-02-17
RecruitingStudy of 111In-XYIMSR-01 SPECT/CT in Patients With Metastatic Clear Cell Renal Cell
Renal Cell Carcinoma (Kidney Cancer)
Phase 12022-01-26
RecruitingTrial of Cemiplimab, or Cemip-Chemo Followed by Biomarker-guided Treatment for Pts w/HPV H&N Ca
HPV-Related Squamous Cell Carcinoma
Phase 22021-12-13
RecruitingMulti-agent Low Dose Chemotherapy GAX-CI Followed by Olaparib and Pembro in Metastatic Pancreatic Ductal Cance
Metastatic Pancreatic Cancer
Phase 22021-09-29
CompletedDurvalumab and SNDX-6532 Following Chemo or Radio-Embolization for Patients With Intrahepatic Cholangiocarcino
Unresectable Intrahepatic Cholangiocarcinoma
Phase 22021-08-24
CompletedHPV in Sinonasal Ca: Retrospective Analysis Association of Human Papilloma Virus (HPV) Serology and Behavioral
Sinonasal Carcinoma, HPV-Related Squamous Cell Carcinoma
2021-08-03
TerminatedIncidence of Intracranial Hemorrhage in Glioma Patients With Venous Thromboembolism Converted From LMWH to Api
Glioma, Malignant
2021-08-01
WithdrawnTA-CIN Vaccine With Anti-PD-1 Therapy in Recurrent HPV16-associated Cancers
Recurrent Human Papillomavirus Type 16 Associated Cancer
Phase 12021-08-01
CompletedNeoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath Tumor
Nerve Sheath Tumors
Phase 12021-06-08
TerminatedBreath-Hold Technique for Pancreatic Stereotactic Body Radiation Therapy (SBRT) Patients
Pancreas Cancer
N/A2021-06-03
Active Not RecruitingFeasibility and Efficacy of Perioperative Nivolumab With or Without Relatlimab for Patients With Potentially R
Hepatocellular Carcinoma
Phase 12021-05-28
Active Not RecruitingNeoadjuvant Targeting of Myeloid Cell Populations in Combination With Nivolumab in Head & Neck Ca
Head and Neck Squamous Cell Carcinoma
Phase 22021-04-24
CompletedThoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupivacaine Following Open Gynecologi
Surgery, Analgesia
Phase 32021-04-14
WithdrawnTrial to Promote Recovery From COVID-19 With Endocrine Therapy
COVID-19, SARS-CoV 2
Phase 22021-04-01
RecruitingCombination Radiotherapy and Radiopharmaceutical Therapy Treatment Planning for Thyroid Cancer
Recurrent Thyroid Cancer
Phase 12021-03-17
CompletedAdaptive Nutrition and Exercise Weight Loss (A-NEW) Study
Breast Cancer, Overweight or Obesity
Phase 22021-02-08
TerminatedCamostat With Bicalutamide for COVID-19
Covid19, SARS-CoV Infection, Coronavirus Infection
Phase 12021-02-03
Terminated[18F]FLOR (FC303) PET/CT Imaging in Patients With Prostate Cancer
Metastatic Prostate Cancer
Phase 12021-02-01
TerminatedPET Imaging With [18F]F-AraG in Advanced Non-small Cell Lung Cancer (NSCLC)
Non-small Cell Lung Cancer (NSCLC)
Phase 12021-02-01
CompletedImproving Cancer On-treatment Symptom Management
Cancer, Thoracic Neoplasms, Gastrointestinal Cancer
2020-11-16
WithdrawnBariatric Arterial Embolization for Men Starting Hormones for Prostate Cancer
Prostate Adenocarcinoma, Obesity, Morbid
Phase 22020-11-16
CompletedPlerixafor and Cemiplimab in Metastatic Pancreatic Cancer
Metastatic Pancreatic Cancer
Phase 22020-11-16
CompletedTheraSphere® For Treatment of Metastases in Liver
Colorectal Cancer Metastatic, Colorectal Cancer
N/A2020-11-12
CompletedA Study of Pemigatinib in Non-muscle Invasive Bladder Cancer Patients With Recurrent Low- or Intermediate-Risk
Bladder Cancer, NMIBC, Non-Muscle Invasive Bladder Cancer
Phase 22020-10-02
CompletedBehavioral Weight Loss Program for Cancer Survivors in Maryland
Breast Cancer, Prostate Cancer, Melanoma (Skin)
N/A2020-09-22
Active Not RecruitingPatient Response to Immunotherapy Using Spliceosome Mutational Markers (PRISMM)
Metastatic Solid Tumor, SF3B1 Gene Mutation, Spliceosome Mutation
2020-09-17
RecruitingHPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia
Human Papillomavirus Type 16, Cervical Intraepithelial Neoplasia Grade II, Cervical Intraepithelial Neoplasia, Grade III
Phase 12020-09-14
RecruitingSequential Testosterone and Enzalutamide Prevents Unfavorable Progression
Castration Resistant Metastatic Prostate Cancer
Phase 22020-08-19
Active Not RecruitingPaclitaxel, Pembrolizumab and Olaparib in Previously Treated Advanced Gastric Adenocarcinoma
Advanced Gastric Adenocarcinoma
Phase 22020-07-31
Active Not RecruitingIntravesical Gemcitabine and Docetaxel for BCG naïve Non-muscle Invasive Bladder Cancer
Urothelial Carcinoma Bladder, Bladder Cancer
Phase 22020-07-29
Active Not RecruitingPooled Mutant KRAS-Targeted Long Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Rese
Colorectal Cancer, Pancreatic Cancer
Phase 12020-05-28
RecruitingDNAJB1-PRKACA Fusion Kinase Peptide Vaccine Combined With Nivolumab and Ipilimumab for Patients With Fibrolame
Fibrolamellar Hepatocellular Carcinoma (FLC)
Phase 12020-04-20
CompletedINCMGA00012 in Patients With Previously Treated Unresectable or Metastatic Adenosquamous Pancreatic or Ampulla
Pancreatic Cancer Non-resectable, Pancreatic Cancer Metastatic
Phase 22020-04-09
RecruitingProton Radiation Therapy Registry
Cancer, Therapy-Related
2020-04-07
CompletedEMPOWER Men to Reduce Weight and Inhibit Prostate Cancer Progression
Prostatic Neoplasm
N/A2020-02-20
Active Not RecruitingTrial of Anti-Tim-3 in Combination With Anti-PD-1 and SRS in Recurrent GBM
Glioblastoma Multiforme
Phase 12020-02-18
CompletedObservation of Perioperative Outcomes of Robotic Pancreaticoduodenectomy
Pancreaticoduodenectomy
N/A2020-02-18
CompletedBGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations
IDH1 Mutation, IDH2 Mutation, Recurrent Glioblastoma
Phase 1 / Phase 22020-02-16
RecruitingRegenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies and Inherited Bone Ma
Primary Immune Deficiency Disorder, Immune Deficiency Disease, Bone Marrow Failure
Phase 22020-02-12
CompletedNivolumab in Biochemically Recurrent dMMR Prostate Cancer
Prostate Cancer, Recurrent Prostate Cancer
Phase 22020-01-13
TerminatedAXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing Surgery
Brain and Central Nervous System Tumors
EARLY_Phase 12020-01-02
CompletedTrial of Neoadjuvant and Adjuvant Nivolumab and BMS-813160 With or Without GVAX for Locally Advanced Pancreati
Locally Advanced Pancreatic Ductal Adenocarcinoma (PDAC), Pancreatic Ductal Adenocarcinoma
Phase 1 / Phase 22019-12-12
TerminatedDetermining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in P
High Grade Glioma, Anaplastic Astrocytoma, Anaplastic Oligodendroglioma
Phase 12019-12-06
WithdrawnSBRT as a Vaccination for Metastatic Melanoma
Metastatic Melanoma
Phase 22019-11-26
TerminatedAssessment of Multi-Modality Quantitative Imaging for Evaluation of Response of Metastatic Prostate Cancer to
Prostate Cancer
Phase 12019-11-15
CompletedCombined Technology Enhanced Home Exercise Program and Other Non-pharmacological Intervention for Cancer Survi
Cancer-related Problem/Condition, Exercise, Acupressure
N/A2019-10-10
CompletedCTLA-4 /PD-L1 Blockade Following Transarterial Chemoembolization (DEB-TACE) in Patients With Intermediate Stag
Intermediate Stage of Hepatocellular Carcinoma, Hepatocellular Carcinoma
Phase 22019-10-02
Active Not RecruitingNeoadjuvant Immune Checkpoint Blockade in Resectable Malignant Pleural Mesothelioma
Mesothelioma
Phase 22019-10-02
WithdrawnStudy of 18F-DCFPyL PET/CT Imaging in Patients With Prostate Cancer
Prostate Cancer
Phase 2 / Phase 32019-10-01
TerminatedAllogeneic Myeloma GM-CSF Vaccine With Lenalidomide in Multiple Myeloma Patients in Complete or Near Complete
Multiple Myeloma
Phase 22019-09-23
WithdrawnTherapy for High-Risk HPV 16-Positive Oropharynx Cancer Patients
HPV Positive Oropharyngeal Squamous Cell Carcinoma, Oropharynx Cancer, HPV-Related Carcinoma
Phase 22019-09-17
TerminatedNeoadjuvant Dupilumab in Men With Localized High-Risk Prostate Cancer
Prostate Cancer
Phase 22019-08-28
CompletedRAdium-223 and SABR Versus SABR for Oligometastatic Prostate Cancers
Prostate Cancer
Phase 22019-08-09
CompletedTailored Home-Based Exercise Program for Multiple Chronic Conditions
Cancer, Hypertension, Diabetes
N/A2019-08-01
TerminatedStudy of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG
High Grade Glioma, BRAF V600E, BRAF V600K
Phase 22019-07-29
CompletedPreoperative Immune Checkpoint Inhibitor for Patients With Primary Untreated or Recurrent/Metastatic SCCHN
Head and Neck Squamous Cell Carcinoma, Head and Neck Cancer, Head and Neck Cancer Metastatic
Phase 22019-07-08
WithdrawnSelective Transvenous Chemoembolization of Primary Pancreatic Tumors
Pancreatic Adenocarcinoma
Phase 12019-07-01
WithdrawnSafety and Tolerability Study of Nivolumab and Cabiralizumab for Resectable Biliary Tract Cancer
Resectable Biliary Tract Cancer
Phase 22019-06-14
TerminatedA Window of Opportunity Study to Investigate Mechanisms of Actions of Novel Therapeutic Agents in Patients Wit
Solid Tumor
Phase 12019-06-06
RecruitingStudy of Olaparib in Metastatic Renal Cell Carcinoma Patients With DNA Repair Gene Mutations
Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma, Kidney Cancer
Phase 22019-06-03
CompletedAssessing Induction of Double Strand Breaks With Androgen Receptor Partial Agonist in Patients on Androgen Sup
Prostate Cancer
EARLY_Phase 12019-05-10
CompletedArtesunate Ointment for the Treatment of High Grade Vulvar Intraepithelial Neoplasia (HSIL VIN2/3)
Vulvar Dysplasia, HPV-Related Vulvar Intraepithelial Neoplasia, Preinvasive Vulvar Disease
Phase 12019-04-17
Active Not RecruitingDose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor With Oral Decitabine in Subjects With Sol
Solid Tumor
Phase 12019-04-17
CompletedSafety and Feasibility of TA-CIN Vaccine in HPV16 Associated Cervical Cancer
HPV16 Associated Cervical Cancer
Phase 12019-04-04
CompletedTest-Retest Reproducibility of 18F-DCFPyL PET/CT in the Evaluation of Patients With Metastatic Prostate Cancer
Prostate Cancer
Phase 12019-03-27
TerminatedBiomarker-Driven Therapy Using Immune Activators With Nivolumab in Patients With First Recurrence of Glioblast
Glioblastoma, Glioblastoma Multiforme
Phase 12019-03-22
TerminatedAutomated Method for Breast Cancer Detection
Breast Cancer Diagnosis
N/A2019-03-07
Active Not RecruitingREACTION (Radiation Enhanced Assessment of Combination Therapies in Immuno-ONcology) - Nivolumab or Nivolumab
Gastroesophageal Cancer, Immune Checkpoint Inhibition
Phase 1 / Phase 22019-03-06
CompletedStudy of Nivolumab and Relatlimab in Patients With Microsatellite Stable (MSS) Advanced Colorectal Cancer
Microsatellite Stable (MSS) Colorectal Adenocarcinomas, Colorectal Adenocarcinoma
Phase 22019-02-12
CompletedStudy of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumor
Unresectable or Metastatic Microsatellite Stable (MSS) Solid Tumor, Microsatellite Stable (MSS) Colon Cancer
Phase 1 / Phase 22019-01-17
CompletedEvaluation of PSMA-based PET as an Imaging Biomarker in Prostate Cancer
Advanced Prostate Cancer
EARLY_Phase 12018-12-06
RecruitingNivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced Unresectable or Metastatic
Basal Cell Carcinoma
Phase 22018-11-27
Active Not RecruitingStudy of Nivolumab and Relatlimab in Advanced Mismatch Repair Deficient Cancers Resistant to Prior PD-(L)1 Inh
Refractory MSI - H Solid Tumors Prior of PD-(L) 1 Therapy, MSI-H Tumors
Phase 22018-11-16
Active Not RecruitingNeoadjuvant Endocrine Therapy, Palbociclib, Avelumab in Estrogen Receptor Positive Breast Cancer
Breast Cancer
Phase 22018-11-13
TerminatedStudy of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas
Lymphopenia, Malignant Glioma
Phase 12018-10-30
TerminatedMuscadine Plus (MPX) In Men With Prostate Cancer
Adenocarcinoma of the Prostate
Phase 32018-10-30
CompletedPathologic and Immunologic Response After Ablative Radiation in Lung Cancer
Non-small Cell Lung Cancer Stage I
N/A2018-10-16
WithdrawnA Pilot Trial of Scrambler Therapy for Pain Associated With Pancreas Cancer
Cancer Pancreas, Pain Syndrome, Cancer Related Pain
2018-10-01
CompletedResiliency in Older Adults Undergoing Bone Marrow Transplant
Leukemia, Lymphoma, Blood Cancer
2018-09-28
CompletedPilot Study With CY, Pembrolizumab, GVAX, and IMC-CS4 (LY3022855) in Patients With Borderline Resectable Adeno
Pancreatic Cancer
EARLY_Phase 12018-09-27
CompletedTrial of Rucaparib in Patients With Metastatic Hormone-Sensitive Prostate Cancer Harboring Germline DNA Repair
Prostate Cancer Metastatic
Phase 22018-09-10
CompletedCOMbination of Bipolar Androgen Therapy and Nivolumab
Castration-resistant Prostate Cancer, Metastatic Prostate Cancer, Prostate Cancer
Phase 22018-09-05
TerminatedSkeletal Metastasis Registry
Metastatic Bone Tumor
2018-08-16
TerminatedIdelalisib Post Allogeneic Hematopoietic Stem Cell Transplant (HSCT) in B Cell Derived Malignancies
B Cells-Tumors, B Cell Chronic Lymphocytic Leukemia, Follicular Lymphoma
Phase 12018-07-31
Active Not RecruitingDeterminants of Resistance to Endocrine Therapy and a Cyclin-dependent Kinases 4 and 6 (CDK4/6) Inhibitor for
Breast Cancer
Phase 22018-07-20
CompletedA Study of Gemcitabine, Nab-paclitaxel, Capecitabine, Cisplatin, and Irinotecan in Metastatic Pancreatic Cance
Adenocarcinoma, Pancreatic Neoplasms, Neoplasm, Glandular
Phase 1 / Phase 22018-06-21
CompletedCancer, Obesity/Overweight and Insomnia Study
Breast Cancer, Overweight and Obesity, Insomnia
N/A2018-06-12
CompletedRadiopaque Hydrogel in Patients Undergoing Radiotherapy for Pancreatic Cancer
Pancreatic Adenocarcinoma
N/A2018-06-06
WithdrawnPilot Study to Define the Immune Response Following Cryoablation of Invasive Breast Cancer
Invasive Ductal Carcinoma, Breast
N/A2018-05-22
TerminatedA Biospecimen Collection Study in BRAF-V600E Mutated Recurrent Gliomas
Glioma, BRAF V600E, Pleomorphic Xantho-Astrocytoma
2018-05-19
CompletedFeasibility and Efficacy of Neoadjuvant Cabozantinib Plus Nivolumab (CaboNivo) Followed by Definitive Resectio
Locally Advanced Hepatocellular Carcinoma
Phase 12018-05-14
TerminatedRadiosurgical Hypophysectomy for Bone Metasteses Pain
Bone Metastases
N/A2018-05-08
CompletedTerameprocol in Treating Patients With Recurrent High Grade Glioma
High Grade Glioma (III or IV)
Phase 12018-05-03
RecruitingTrial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With
Sarcoma, Solid Tumor, Adult, Solid Tumor, Childhood
Phase 1 / Phase 22018-05-01
CompletedClinical Trial of Combined Fostamatinib and Paclitaxel in Ovarian Cancer
Ovarian Cancer
Phase 12018-04-03
Active Not RecruitingStudy of PSMA-targeted 18F-DCFPyL PET/CT for the Detection of Clinically Significant Prostate Cancer
Prostate Cancer
Phase 22018-03-29
TerminatedNivolumab With Ipilimumab in Subjects With Neuroendocrine Tumors
Neuroendocrine Tumors, Carcinoid Tumor
Phase 22018-03-09
CompletedGVAX Pancreas Vaccine (With CY) in Combination With Nivolumab and SBRT for Patients With Borderline Resectable
Pancreatic Cancer
Phase 22018-02-02
CompletedEpacadostat, Pembrolizumab, and CRS-207, With or Without CY/GVAX Pancreas in Patients With Metastatic Pancreas
Metastatic Pancreatic Adenocarcinoma
Phase 22018-01-31
Active Not RecruitingPersonalized Molecular Profiling in Cancer Treatment at Johns Hopkins
Metastatic Breast Cancer
N/A2018-01-26
CompletedStudy of MK-3475 (Pembrolizumab) in Patients With Microsatellite Unstable (MSI) Tumors (Cohort D)
High Tumor Mutation Burden, High TMB (Tumor Mutation Burden), MSS (Microsatellite Stable)
Phase 22018-01-25
CompletedStudy of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cy) in Patients With P
Pancreatic Cancer
Phase 22017-12-14
CompletedTranscranial Direct Current Stimulation (tDCS) to Improve Fatigue and Cognitive Function
Breast Cancer, Fatigue
N/A2017-12-12
TerminatedNeoadjuvant Immunoradiation for Resectable Non-Small Cell Lung Cancer
Non-Small Cell Lung Cancer
Phase 22017-12-12
CompletedNon-Invasive Neurosensory Testing For Chemotherapy-Induced Peripheral Neuropathy
Cancer, Malignancy, Malignant Neoplasm
2017-11-29
CompletedA Clinical Trial of Entinostat in Combination With Nivolumab for Patients With Previously Treated Unresectable
Metastatic Cholangiocarcinoma, Cholangiocarcinoma, Pancreatic Cancer
Phase 22017-11-06
Completed5 Fraction Stereotactic Radiosurgery With Temozolomide for Glioblastoma Multiforme
Glioblastoma Multiforme
EARLY_Phase 12017-10-18
TerminatedMEDI-551 as Maintenance Therapy After Allogeneic Stem Cell Transplant in Multiple Myeloma
Multiple Myeloma
Phase 22017-09-27
CompletedAssessing the Acceptability of the Use of a Mobile Health App Among Young Adult Female Survivors of Childhood
Childhood Cancer Survivor
N/A2017-09-26
CompletedHIF-2 Alpha Inhibitor PT2385 in Treating Patients With Recurrent Glioblastoma
Recurrent Glioblastoma
Phase 22017-09-14
Active Not RecruitingA Study of Blinatumomab in Patients With Pre B-cell ALL and B-cell NHL as Post-allo-HSCT Remission Maintenance
Acute Lymphoblastic Leukemia, B-cell Non Hodgkin Lymphoma, Pre B-Cell Acute Lymphoblastic Leukaemia
Phase 1 / Phase 22017-09-05
TerminatedStudy of Stereotactic Radiotherapy for Breast Cancer
Breast Cancer
Phase 22017-08-01
CompletedInvolving Family to Improve Communication in Breast Cancer Care
Active Breast Cancer Treatment
N/A2017-07-20
RecruitingNeurocognitive Functioning With Genu-Sparing Whole Brain Radiation Therapy for Brain Metastases
Brain Metastases
N/A2017-07-19
Active Not RecruitingNivolumab +/- Relatlimab Prior to Chemoradiation With II/III Gastro/Esophageal Cancer
Gastric Cancer, Esophageal Cancer, GastroEsophageal Cancer
Phase 12017-07-11
CompletedStudy of GVAX (With CY) and Pembrolizumab in MMR-p Advanced Colorectal Cancer
Metastatic Colorectal Cancer
Phase 22017-05-26
Active Not RecruitingNeoadjuvant Nivolumab With and Without Urelumab in Cisplatin-Ineligible or Chemotherapy-refusing Patients With
Urothelial Carcinoma, Bladder Cancer
Phase 22017-05-16
TerminatedPembrolizumab in Patients With Leptomeningeal Disease
Patients With Leptomeningeal Disease
Phase 22017-04-12
TerminatedStudy Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblasto
Medulloblastoma
EARLY_Phase 12017-04-04
TerminatedCohorts of Docetaxel or Cabazitaxel in Combination With the Potent CYP3A4 Inhibitor, Clarithromycin
Prostate Cancer
Phase 12017-03-21
CompletedPost-Operative Outcomes of Low Thermal Dissection vs. Traditional Electrosurgery
Breast Cancer, Mastectomy, Perfusion; Complications
N/A2017-03-17
Active Not RecruitingNivolumab With or Without Stereotactic Radiosurgery in Treating Patients With Recurrent, Advanced, or Metastat
Chordoma
Phase 12017-03-10
Active Not RecruitingOlaparib in Men With High-Risk Biochemically-Recurrent Prostate Cancer Following Radical Prostatectomy, With I
Prostate
Phase 22017-03-01
CompletedTrial of Mistletoe Extract in Patients With Advanced Solid Tumors
Solid Tumor
Phase 12017-03-01
CompletedA Study of Definitive Therapy to Treat Prostate Cancer After Prostatectomy
Prostate Cancer
Phase 22017-02-22
Active Not RecruitingNeoadjuvant Enoblituzumab (MGA271) in Men With Localized Intermediate and High-Risk Prostate Cancer
Prostate Cancer
Phase 22017-02-14
TerminatedSex-Mismatched Allogeneic Bone Marrow Transplantation for Men With Metastatic Castration-Resistant Prostate Ca
Prostate Cancer
Phase 12017-02-09
TerminatedStudy of IRX5183 in Relapsed and Refractory Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome
Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), Chronic Myelomonocytic Leukemia (CMML)
Phase 12017-01-30
WithdrawnMarkers for Predicting Risk of Breast Cancer in Women of Different Races
Breast Cancer
2017-01-01
RecruitingImage-Guided Gynecologic Brachytherapy
Cervical Cancer, Uterine Cancer, Vaginal Cancer
N/A2016-12-15
CompletedPerspectives on Bone Marrow Donors Who Donate for Their Parent
Bone Marrow Transplant
2016-12-06
TerminatedPhase 2 Study of Nivolumab in Solid Tumors Induced by Prior Radiation Exposure
Solid Tumors Induced by Prior Radiation Exposure
Phase 22016-12-01
Active Not RecruitingPalbociclib With Fulvestrant for Metastatic Breast Cancer After Treatment With Palbociclib and an Aromatase In
Metastatic Breast Cancer
Phase 22016-10-25
TerminatedNonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythematosus (S
Lupus Erythematosus, Graft-versus-host Disease
Phase 1 / Phase 22016-09-13
CompletedNMA Haplo or MUD BMT for Newly Diagnosed Severe Aplastic Anemia
Severe Aplastic Anemia, Aplastic Anemia, Bone Marrow Failure
Phase 22016-09-01
RecruitingImmunobiology Blood and Tissue Collection of Upper Aerodigestive Malignancies
Head and Neck Cancer, Lung Cancer, Gastrointestinal Cancer
2016-08-25
CompletedAnti-LAG-3 Alone & in Combination w/ Nivolumab Treating Patients w/ Recurrent GBM (Anti-CD137 Arm Closed 10/16
Glioblastoma, Gliosarcoma, Recurrent Brain Neoplasm
Phase 12016-08-24
CompletedComparison of PSMA-based 18F-DCFPyL PET/CT to Conventional Imaging in the Evaluation of Patients With Castrati
Prostate Cancer
2016-08-03
CompletedStudy With CY, Pembrolizumab, GVAX Pancreas Vaccine, and SBRT in Patients With Locally Advanced Pancreatic Can
Pancreatic Cancer
Phase 22016-07-18
CompletedStudy of Azacitidine in Combination With Pembrolizumab in R/R AML Patients and in Newly Diagnosed Older Patien
Acute Myeloid Leukemia
Phase 22016-07-01
Active Not RecruitingMonitoring Plasma Tumor DNA in Early-Stage Breast Cancer
Breast Cancer
2016-07-01
TerminatedPilot Study of Mobilization and Treatment of Disseminated Tumor Cells in Men With Metastatic Prostate Cancer
Prostate Cancer
Phase 12016-07-01
CompletedSRS and Nivolumab in Treating Patients With Newly Diagnosed Melanoma Metastases in the Brain or Spine
Metastatic Malignant Neoplasm in the Brain, Metastatic Malignant Neoplasm in the Spine, Stage IV Skin Melanoma
Phase 12016-06-23
TerminatedDocetaxel With or Without Ascorbic Acid in Treating Patients With Metastatic Prostate Cancer
Hormone-Resistant Prostate Cancer, Metastatic Prostate Carcinoma, Stage IV Prostate Cancer
Phase 22016-06-20
WithdrawnHead and Neck Cancer Treatment Related Dysphagia
Head and Neck Cancer, Dysphagia
2016-06-09
CompletedStudy of the Clinical Utility of PSMA Imaging in the Evaluation of Men With Prostate Cancer
Prostate Cancer
2016-06-08
CompletedA Study of Definitive Therapy to Treat Prostate Cancer
Prostate Cancer
Phase 22016-06-01
CompletedEvaluation of 18F-DCFPyL PSMA- Versus 18F-NaF-PET Imaging for Detection of Metastatic Prostate Cancer.
Metastatic Prostate Cancer
Phase 12016-05-16
Active Not RecruitingStudy of TGF-β Receptor Inhibitor Galunisertib (LY2157299) and Enzalutamide in Metastatic Castration-resistant
Prostate Cancer
Phase 22016-05-03
CompletedPhase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors
Medulloblastoma, Astrocytoma, Grade III, Glioblastoma
Phase 12016-05-01
TerminatedUltrasound Monitoring of Abdominal Soft Tissue
Pancreatic Cancer, Liver Cancer
N/A2016-05-01
CompletedStereotactic Body Radiation for Prostate Oligometastases
Prostate Cancer, Oligometastases
Phase 22016-04-28
Active Not RecruitingPlatform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pa
Pancreatic Cancer
Phase 22016-03-28
CompletedBiomarker-Driven Therapy With Nivolumab and Ipilimumab in Treating Patients With Metastatic Hormone-Resistant
Prostate Cancer, Recurrent Prostate Carcinoma, Stage IV Prostate Adenocarcinoma
Phase 22016-03-15
WithdrawnSequential, Related Donor Partial Liver Transplantation Followed by Bone Marrow Transplantation for Hepatocell
Fibrolamellar Hepatocellular Carcinoma, Hepatocellular Carcinoma (Fibrolamellar Variant), Hepatocellular Carcinoma
Phase 22016-03-01
CompletedStudy of Sipuleucel-T W/ or W/O Radium-223 in Men With Asymptomatic or Minimally Symptomatic Bone-MCRPC
Prostate Cancer
Phase 22016-02-22
CompletedA Study of Enhancing Response to MK-3475 in Advanced Colorectal Cancer
Colorectal Cancer
Phase 12016-02-19
CompletedStudy of Neoadjuvant Nivolumab in Patients With Non-metastatic Stage II-IV Clear Cell Renal Cell Carcinoma
Clear Cell Renal Cell Carcinoma
Phase 12016-02-01
CompletedVibrent Smartphone Mobile Application
Mucositis
N/A2016-01-14
TerminatedStudy of Tremelimumab Alone or Combined With Olaparib for Patients With Persistent EOC (Epithelial Ovarian, Fa
Primary Peritoneal Carcinoma
Phase 12016-01-08
CompletedPembrolizumab and Cryosurgery in Treating Patients With Newly Diagnosed, Oligo-metastatic Prostate Cancer
Stage IV Prostate Cancer
N/A2015-12-11
CompletedShorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft Malig
Myelodysplastic Syndrome, Chronic Myelomonocytic Leukemia, Small Lymphocytic Lymphoma
Phase 22015-12-01
CompletedSimplifying Survivorship Care Planning
Cancer
N/A2015-10-01
TerminatedDexamethasone Prior to Re-treatment With Enzalutamide in Treating Patients With Metastatic Hormone-Resistant P
Hormone-Resistant Prostate Cancer, Metastatic Prostate Carcinoma, Prostate Adenocarcinoma
N/A2015-09-01
WithdrawnTrial of Vemurafenib and Cobimetinib in Patients With Advanced BRAFV600 Mutant Melanoma
Melanoma
Phase 32015-08-01
CompletedMyeloablative Haploidentical BMT With Post-transplant Cyclophosphamide for Pediatric Patients With Hematologic
Myeloablative Conditioning, HLA-mismatched Bone Marrow Transplantation, Graft Survival
Phase 22015-07-02
CompletedA Safety Study of Fingolimod With Radiation and Temozolomide in Newly Diagnosed High Grade Glioma
Glioblastoma, Anaplastic Astrocytoma
EARLY_Phase 12015-07-01
CompletedUtilizing Advance Care Planning Videos to Empower Perioperative Cancer Patients and Families
Cancer
N/A2015-07-01
CompletedPilot Study of 18F-DCFPyL PET/CT in the Evaluation of Men With an Elevated PSA Following Radical Prostatectomy
Adenocarcinoma of the Prostate
N/A2015-06-02
CompletedAdoptive Immunotherapy With Activated Marrow Infiltrating Lymphocytes and Cyclophosphamide Graft-Versus-Host D
Hematologic Malignancies, Graft-Versus-Host Disease
Phase 12015-05-28
CompletedSurvivorship Promotion In Reducing IGF-1 Trial
Breast Cancer, Prostate Cancer, Lung Cancer
Phase 22015-05-01
CompletedEvaluating the Effects of Psycho-oncological Education on Distress and Quality of Life in Solid Tumor Cancer P
Quality of Life
N/A2015-05-01
CompletedRandomized Salvage Radiation Therapy Plus Enzalutamide Post Prostatectomy
Adenocarcinoma of the Prostate
Phase 22015-03-28
TerminatedFBnTP Imaging of Breast Cancer
Breast Cancer
Phase 12015-03-12
WithdrawnA Study of Radium-223 in Combination With Tasquinimod in Bone-only Metastatic Castration-Resistant Prostate Ca
Prostate Cancer, Bone-only Metastatic Castration-Resistant Prostate Cancer (CRPC)
Phase 12015-03-01
CompletedScrambler Therapy in the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy
Neuropathy
N/A2015-03-01
CompletedTargeted Imaging of Glutamate Carboxypeptidase II With DCFPyL-PET
Schwannomas, Malignant Tumors
Phase 12015-02-06
CompletedStudy of Gemcitabine/Taxotere/Xeloda (GTX) in Combination With Cisplatin and Irinotecan in Subjects With Metas
Metastatic Pancreatic Adenocarcinoma
Phase 1 / Phase 22015-02-01
CompletedIntravaginal Artesunate for the Treatment of HPV+ High Grade Cervical Intraepithelial Neoplasia (CIN2/3)
Cervical Intraepithelial Neoplasia Grade 2/3, High-risk HPV (Any Strain)
Phase 12015-02-01
CompletedPatient and Provider Initiated Survivorship Care Planning
Cancer
N/A2015-02-01
CompletedBrain Interstitium Temozolomide Concentration Pre and Post Regadenoson Administration
Blood Brain Barrier Defect
EARLY_Phase 12015-02-01
CompletedImmunologic Responses in HPV-Associated Carcinoma for Patients Receiving Chemoradiation
Head and Neck Cancer, HPV (Human Papillomavirus)-Associated Carcinoma, Oropharyngeal
2015-01-07
CompletedGVAX Pancreas Vaccine (With CY) and CRS-207 With or Without Nivolumab
Previously Treated Metastatic Adenocarcinoma of the Pancreas
Phase 22015-01-02
CompletedTestosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates Enzalutamide Resist
Castration Resistant Metastatic Prostate Cancer
Phase 22015-01-01
CompletedCancer DNA Detection in Blood and Urine
Prostate Cancer
2014-11-01
CompletedIntraoperative Dosimetry for Prostate Brachytherapy Using Fluoroscopy and Ultrasound
Prostate Cancer, Adenocarcinoma of the Prostate
N/A2014-10-01
Active Not RecruitingNeoadjuvant Nivolumab, or Nivolumab in Combination With Ipilimumab, in Resectable NSCLC
Non-Small Cell Lung Cancer
Phase 22014-09-01
WithdrawnNeoadjuvant Doxorubicin/Cyclophosphamide Followed by Eribulin Chemotherapy (ACE) in Operable HER2-negative Bre
Breast Cancer
Phase 22014-09-01
WithdrawnReiki as a Complementary Therapy: A Pilot Study
Hematologic Malignancy
N/A2014-09-01
CompletedRE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study)
Prostate Cancer
Phase 22014-08-25
TerminatedPilot Study Using Amide Proton Transfer Magnetic Resonance Imaging Distinguishing Glioma
Gliosarcoma, Glioma
N/A2014-08-01
CompletedTransplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory
Severe Aplastic Anemia, Bone Marrow Failure Syndromes
Phase 22014-08-01
Active Not RecruitingSubventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme
Glioblastoma Multiforme
Phase 22014-07-08
TerminatedNelfinavir for the Treatment of Gammaherpesvirus-Related Tumors
Non-Hodgkin Lymphoma, Hodgkin Lymphoma, Kaposi Sarcoma
EARLY_Phase 12014-07-01
CompletedChemoradiation or Brachytherapy for Rectal Cancer
Rectal Cancer
Phase 22014-06-12
CompletedA Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects
Metastatic Pancreatic Adenocarcinoma
Phase 12014-06-10
TerminatedStudy of Rituximab and Brentuximab Vedotin for Relapsed Classical Hodgkin Lymphoma
Lymphoma
Phase 12014-06-01
TerminatedDetection and Prevention of Anthracycline-Related Cardiac Toxicity With Concurrent Simvastatin
Breast Cancer, Stage I Breast Cancer, Stage II Breast Cancer
Phase 22014-05-20
CompletedA Comprehensive Smoking Cessation Intervention Duration Radiation for Upper Aerodigestive Cancers
Tobacco Use Disorder, Head and Neck Neoplasms, Thoracic Neoplasms
N/A2014-05-01
CompletedStudy of 18F-DCFPyL, a Second Generation Low-molecular Weight PSMA-based PET Radiotracer, in Patients With Pro
Metastatic Prostate Cancer
Phase 12014-05-01
CompletedLenalidomide, Dexamethasone and MEDI-551 in Untreated Multiple Myeloma
Myeloma
EARLY_Phase 12014-05-01
CompletedSGI-110 in Combination With an Allogeneic Colon Cancer Cell Vaccine (GVAX) and Cyclophosphamide (CY) in Metast
Metastatic Colorectal Cancer
Phase 12014-04-14
CompletedRed Cell Transfusion Goals in Patients With Acute Leukemias
Acute Lymphoblastic Leukemia, Acute Lymphocytic Leukemia (ALL), Acute Myelogenous Leukemia (AML)
Phase 12014-04-01
WithdrawnIntegrating Palliative Care and Modern Palliative Care Tools Into the Care of Patients With Pancreas Cancer
Pancreas Cancer
2014-04-01
CompletedA Study of Vismodegib in Men With Metastatic CRPC With Accessible Metastatic Lesions for Tumor Biopsy
Prostate Cancer
EARLY_Phase 12014-04-01
CompletedA Pre-surgical Study of LDE225 in Men With High-risk Localized Prostate Cancer
Prostate Cancer
Phase 12014-04-01
WithdrawnA Phase 2 Study of Bicalutamide Plus Finasteride in Men With MRI Detectable Prostate Nodules Undergoing Active
Detectable Prostate Nodules
Phase 22014-03-01
Active Not RecruitingPertuzumab and Trastuzumab as Neoadjuvant Treatment in Patients With HER2-Positive Breast Cancer
Breast Cancer
Phase 22014-01-30
CompletedTrial to Improve Outcomes in Patients With Resected Pancreatic Cancer (Azacitidine)
Pancreatic Cancer
Phase 22014-01-10
CompletedStereotactic Body Radiation With Nelfinavir for Oligometastases
Oligometastases
Phase 22014-01-08
CompletedA Pilot Study of Allopurinol As A Modifier of 6-MP Metabolism in Pediatric ALL
Acute Lymphoblastic Leukemia (ALL)
EARLY_Phase 12014-01-06
TerminatedConsolidation Therapy for Acute Myeloid Leukemia Guided by Leukemia Stem Cell Behavior
Acute Myeloid Leukemia
Phase 2 / Phase 32013-12-01
CompletedPhase II Anti-PD1 Epigenetic Therapy Study in NSCLC.
Non-Small Cell Lung Cancer, Epigenetic Therapy
Phase 22013-11-06
CompletedFOLFIRINOX Followed by Ipilimumab With Pancreatic Tumor Vaccine in Treatment of Metastatic Pancreatic Cancer
Metastatic Pancreatic Adenocarcinoma
Phase 22013-11-01
CompletedStereotactic Radiation Therapy for Pediatric Sarcomas
Sarcoma, Metastatic Disease, Bony Sites
N/A2013-11-01
CompletedPhase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer
Previously Treated Metastatic Colorectal Cancer
Phase 1 / Phase 22013-10-23
TerminatedAllogeneic Human Bone Marrow Derived Mesenchymal Stem Cells in Localized Prostate Cancer
Prostate Cancer
Phase 12013-10-01
CompletedTumor Motion Management in Radiotherapy Using 4D-MRI
Cancer
2013-10-01
CompletedIMAGE Study: Personalized Molecular Profiling in Cancer Treatment at Johns Hopkins
Metastatic Breast Cancer
N/A2013-09-19
CompletedStudy of MK-3475 in Patients With Microsatellite Unstable (MSI) Tumors (Cohorts A, B and C)
MSI Positive Colorectal Cancer, MSI Negative Colorectal Cancer, MSI Positive Non-Colorectal Cancers
Phase 22013-09-01
TerminatedSRS (Stereotactic Radiosurgery) Plus Ipilimumab
Newly Diagnosed Melanoma Metastases in the Brain and Spine
Phase 12013-09-01
CompletedTadalafil and Lenalidomide Maintenance With or Without Activated Marrow Infiltrating Lymphocytes (MILs) in Hig
Multiple Myeloma
Phase 22013-09-01
TerminatedCombination of External Beam Radiotherapy With 153Sm-EDTMP to Treat High Risk Osteosarcoma
Metastatic Osteosarcoma
Phase 22013-08-19
CompletedRobot-Assisted MRI-Guided Prostate Biopsy
Prostate Cancer
N/A2013-07-25
CompletedPOWER-remote Weight Loss Program in Early Stage Breast Cancer
Early Stage Breast Cancer
N/A2013-07-01
CompletedPhase II Study of Azacitidine and Sargramostim as Maintenance Treatment for Poor-Risk AML or MDS
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Phase 22013-06-01
CompletedOptimized Antiretroviral Therapy During Allogeneic Hematopoietic Stem Cell Transplantation in HIV-1 Individual
HIV
EARLY_Phase 12013-06-01
CompletedRadiation and Androgen Ablation for Prostate Cancer
Adenocarcinoma of the Prostate
Phase 1 / Phase 22013-05-22
CompletedRadiotherapy for Solid Tumor Spine Metastases
Solid Tumor Spine Metastases
Phase 22013-05-20
CompletedMebendazole in Newly Diagnosed High-Grade Glioma Patients Receiving Temozolomide
Newly Diagnosed High-Grade Glioma
Phase 12013-04-04
RecruitingReduced Intensity Haploidentical BMT for High Risk Solid Tumors
Refractory and/or Relapsed Metastatic Solid Tumors
Phase 22013-03-27
CompletedHippocampal Prophylactic Cranial Irradiation for Small Cell Lung Cancer
Small-cell Lung Cancer, SCLC, Small Cell Lung Cancer Limited Stage
N/A2013-03-11
CompletedIntra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).
Diffuse Intrinsic Pontine Glioma (DIPG)
Phase 12013-03-08
CompletedEvaluation of 18F-DCFBC PSMA-based PET Imaging for Detection of Metastatic Prostate Cancer
Metastatic Prostate Cancer
Phase 1 / Phase 22013-03-01
TerminatedA Randomized Phase II Study of SUBATM-itraconazole in Patients With Untreated Squamous NSCLC.
Non-small Cell Lung Cancer Metastatic
Phase 22013-03-01
CompletedGroup Intervention to Increase Physical Activity in Childhood Cancer Survivors
Pediatric Cancer
EARLY_Phase 12013-02-01
CompletedA Neoadjuvant Study of Androgen Ablation Combined With Cyclophosphamide and GVAX Vaccine for Localized Prostat
Prostate Cancer Adenocarcinoma in Situ
Phase 1 / Phase 22013-01-18
CompletedBipolar Androgen-based Therapy for Prostate Cancer (BAT)
Recurrent Prostate Cancer
Phase 22013-01-01
CompletedDIG-HIF-1 Pharmacodynamic Trial in Newly Diagnosed Operable Breast Cancer
Breast Cancer
Phase 22013-01-01
CompletedPalliative Stereotactic Radiation for Pancreatic or Periampullary Adenocarcinoma
Pancreatic Cancer, Periampullary Adenocarcinoma
Phase 22013-01-01
TerminatedA Phase I/II Study Afatinib/Carboplatin/Paclitaxel Induction Chemotherapy In HPV-Negative HNSCC.
Squamous Cell Carcinoma of the Head and Neck
Phase 1 / Phase 22012-12-01
CompletedPhase II Study Using CHFR Methylation Status in Patients With Metastatic Esophageal, Gastroesophageal, Gastric
Metastatic Esophageal Cancer, Gastroesophageal Cancer, Gastric Cancer
Phase 22012-12-01
Active Not RecruitingMRI for Assessing Prostate Cancer Response
Prostate Cancer
N/A2012-11-16
CompletedPancreatic Tumor Cell Vaccine (GVAX), Cyclophosphamide, SBRT, and FOLFIRINOX in Patients With Resected Adenoca
Pancreatic Cancer
Phase 22012-10-29
CompletedEvaluation of Prostate-specific Membrane Antigen (PSMA)-Based PET Imaging of Primary Prostate Cancer
Prostate Cancer
Phase 1 / Phase 22012-09-11
TerminatedGemcitabine and Docetaxel in Patients With Relapsed or Refractory Metastatic Colorectal Adenocarcinoma
Metastatic Colorectal Adenocarcinoma
Phase 22012-09-10
CompletedMaintenance Rituximab With mTor Inhibition After High-dose Consolidative Therapy in Lymphoma
CD20+, B-cell Lymphomas, Mantle Cell Lymphoma, Non-Mantle Cell Low Grade B Cell Lymphomas (SLL/CLL)
Phase 22012-09-01
CompletedLow Dose Radiation Therapy for Glioblastoma Multiforme
High Grade Glioma
Phase 22012-09-01
CompletedA Phase II Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract
Head and Neck Squamous Cell Carcinoma
Phase 22012-09-01
TerminatedA Phase 1 Trial of TST of PD 0332991 Followed by Cytarabine and Mitoxantrone for Adults With Relapsed and Refr
Relapsed Acute Leukemia, Refractory Acute Leukemia, High-Risk Myelodysplasia
Phase 12012-09-01
TerminatedPhase I Study of Orally Administered Aminolevulinic Acid for Resection of Malignant Astrocytomas
Astrocytoma, Glioma
Phase 12012-09-01
CompletedProspective Evaluation of T-cell Immune Status in Patients With Newly Diagnosed High Grade Gliomas
High Grade Glioma
N/A2012-07-13
TerminatedPre-Prostatectomy Lovastatin on Prostate Cancer
Prostate Cancer
N/A2012-07-13
CompletedFeasibility of Lymphocyte Reinfusion in Newly Diagnosed High Grade Gliomas
Glioblastoma
N/A2012-07-01
CompletedMibefradil Dihydrochloride and Temozolomide in Treating Patients With Recurrent Glioma
Brain and Central Nervous System Tumors
Phase 12012-05-31
CompletedJohns Hopkins Breast Cancer Program Hormone Therapy Longitudinal Database
Breast Cancer
2012-05-09
TerminatedStudy of Metformin Plus Paclitaxel/Carboplatin/Bevacizumab in Patients With Adenocarcinoma.
Carcinoma, Non-Small-Cell Lung, Lung Adenocarcinoma
Phase 22012-05-01
CompletedPET Quantitative Assessments of Solid Tumor Response to Immune Checkpoint Blockade Therapy
Melanoma, Renal Cell Carcinoma (RCC), Non-small Cell Lung Cancer (NSCLC)
EARLY_Phase 12012-04-16
TerminatedSafety Study of HPV DNA Vaccine to Treat Head and Neck Cancer Patients
Head and Neck Cancer
Phase 12012-04-01
TerminatedAdministration of Tadalafil in Conjunction With Lenalidomide and Dexamethasone in Patients With Multiple Myelo
Multiple Myeloma
Phase 22012-04-01
CompletedA Trial of Oral 5-azacitidine in Combination With Romidepsin in Advanced Solid Tumors, With an Expansion Cohor
Solid Tumors, Virally Mediated Cancers and Liposarcoma
Phase 12012-02-01
CompletedAllogeneic GM-CSF Vaccine and Lenalidomide in Treating Myeloma Patients With Near Complete Remission
Multiple Myeloma
Phase 22012-01-01
TerminatedA Feasibility Study of a Modular Video Augmentation System for Image-Guided Skull Base Surgery
Feasibility of Video Augmentation System, Value of Video Augmentation Navigation
N/A2012-01-01
CompletedNeural Progenitor Cell Sparing Radiation Therapy Plus Temozolomide
Glioblastoma Multiforme
N/A2011-12-27
TerminatedGemcitabine + Nab-paclitaxel With LDE-225 (Hedgehog Inhibitor) as Neoadjuvant Therapy for Pancreatic Adenocarc
Pancreatic Ductal Adenocarcinoma
Phase 1 / Phase 22011-12-27
CompletedGemcitabine/Taxotere/Xeloda (GTX) With Cisplatin in Subjects With Metastatic Pancreatic Cancer
Pancreatic Cancer
Phase 22011-11-01
CompletedPhase 1 Study of Pazopanib With GSK1120212 in Advanced Solid Tumors, Enriched With Patients With Differentiate
Solid Tumors, Thyroid Cancer, Soft-tissue Sarcoma
Phase 12011-10-01
TerminatedDecision Support for Women With Breast Cancer
Breast Neoplasms
N/A2011-09-01
CompletedSafety Study of a Melanoma Vaccine (GVAX) With or Without Cyclophosphamide in Patients With Surgically Resecte
Melanoma
Phase 12011-09-01
CompletedShorter Course Tacrolimus After Nonmyeloablative, Related Donor BMT With High-dose Posttransplantation Cycloph
Hodgkin's Lymphoma, Leukemia, Myelodysplastic Syndrome(MDS)
Phase 12011-08-01
CompletedEffects of Two Doses of MPX Capsules on Rising Prostate-specific Antigen Levels in Men Following Initial Thera
Prostate Cancer
Phase 1 / Phase 22011-07-01
CompletedEndothelial Function, Arterial Stiffness and Components
Acute Lymphoblastic Leukemia
2011-06-01
TerminatedCHFR Methylation Status Esophageal Cancer Study
Esophageal Cancer
Phase 22011-06-01
TerminatedBone Marrow Transplant Trial for Patients With Refractory Severe Aplastic Anemia
Severe Aplastic Anemia
Phase 22011-06-01
CompletedEvaluation of a Transrectal Scintigraphic Detector(ProxiScanTM) for Detection of Primary Prostate Cancer
Suspected Primary Prostate Cancer
Phase 12011-05-01
TerminatedPatient-donor Vaccination in the Context of Allogeneic Bone Marrow Transplant With Post-transplant Cyclophosph
Transplant-Related Cancer
Phase 22011-04-01
TerminatedIntra-arterial Chemotherapy for the Treatment of Intraocular Retinoblastoma
Retinoblastoma
Phase 22011-03-01
TerminatedA Study of Vorinostat and Tamoxifen in Newly Diagnosed Breast Cancer
Stage I Breast Cancer, Stage II Breast Cancer, Stage III Breast Cancer
Phase 22011-03-01
CompletedZoledronic Acid in Aromatase Inhibitor Induced Musculoskeletal Symptoms
Ductal Carcinoma in Situ, Estrogen Receptor-positive Breast Cancer, Progesterone Receptor-positive Breast Cancer
Phase 22011-02-01
CompletedTrial of ICM With or Without AZD2281 (Olaparib) in Patients With Advanced Pancreatic Cancer
Pancreatic Cancer
Phase 12011-01-01
Completed124I-FIAU Imaging in EBV and KSHV Associated Cancers
Hodgkin Lymphoma, Non Hodgkin Lymphoma, Kaposi's Sarcoma
N/A2010-12-01
CompletedStudy of High-Dose-Rate Endorectal Brachytherapy (HDRBT) in the Treatment of Locally Advanced Low Rectal Cance
Rectal Cancer
N/A2010-10-26
CompletedHedgehog Inhibitors for Metastatic Adenocarcinoma of the Pancreas
Metastatic Pancreatic Cancer
Phase 22010-09-17
CompletedReduced Intensity, Partially HLA Mismatched BMT to Treat Hematologic Malignancies
Hematologic Malignancies
Phase 1 / Phase 22010-09-01
CompletedBiodistribution and Pharmacokinetic Study of 18F-DCFBC Prostate Specific Membrane Antigen Based PET in Patient
Prostate Cancer
Phase 12010-09-01
TerminatedReduced-intensity, Related-donor Bone Marrow Transplantation Followed by High-dose Cyclophosphamide for Hemato
Lymphoma, Leukemia, Myelodysplastic Syndrome
Phase 22010-08-01
CompletedRamucirumab or Anti-PDGFR Alpha Monoclonal Antibody IMC-3G3 in Treating Patients With Recurrent Glioblastoma M
Adult Glioblastoma Multiforme
Phase 22010-07-01
CompletedStudy of Recurrent Prostate Cancer With Rising Prostate Specific Antigen (PSA)
Prostate Cancer
N/A2010-05-01
Active Not RecruitingBoost GVAX Pancreas Vaccine With or Without CY in Patients With Pancreas Cancer
Pancreatic Cancer
Phase 22010-04-20
CompletedTreatment De-Intensification for Squamous Cell Carcinoma of the Oropharynx
Squamous Cell Carcinoma of Oropharynx
Phase 22010-03-01
CompletedA Pilot Study of Parenteral Testosterone and Oral Etoposide as Therapy for Men With Castration Resistant Prost
Prostate Cancer
N/A2010-03-01
TerminatedAn Early Safety and Efficacy Study of Ascites Management: Standard Paracentesis or Early Intervention With Ple
Malignant Ascites
N/A2010-02-01
CompletedTrial of Activated Marrow Infiltrating Lymphocytes Alone or in Conjunction With an Allogeneic Granulocyte Macr
Multiple Myeloma
Phase 22010-01-15
CompletedCytokine Expression During Radiation for Breast Cancer
Breast Cancer
N/A2009-11-13
TerminatedRAD001 in Combination With Cetuximab and Cisplatin in Recurrent and Metastatic SCCHN
Head and Neck Cancer
Phase 1 / Phase 22009-10-01
CompletedUsing High Resolution Function Imaging To Detect Melanoma and Dysplastic Nevi
Melanoma
2009-09-22
CompletedSafety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma
Sarcoma
Phase 1 / Phase 22009-09-01
CompletedTherapeutic Vaccination for Patients With HPV16+ Cervical Intraepithelial Neoplasia (CIN2/3)
HPV16 Positive, Cervical Intraepithelial Neoplasia (CIN 2/3)
Phase 12009-09-01
CompletedABT-888, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Brain and Central Nervous System Tumors
Phase 12009-07-13
TerminatedOptimized Donor Selection, Nonmyeloablative BMT for B-cell Lymphomas With Post-transplantation Cy and Rituxima
Lymphoma, B-cell Lymphoma, Non Hodgkin Lymphoma
Phase 22009-07-01
CompletedCyclophosphamide and Vaccine Therapy With or Without Trastuzumab in Treating Patients With Metastatic Breast C
Breast Cancer
Phase 22009-07-01
TerminatedA Study of Dasatinib, Cetuximab and Radiation With or Without Cisplatin in HNSCC
Head and Neck Cancer
Phase 12009-07-01
TerminatedTrial of High Dose Lenalidomide in Patients With MDS and AML With Trilineage Dysplasia
Myelodysplastic Syndrome
Phase 22009-07-01
CompletedConcentration and Activity of Lapatinib in Vestibular Schwannomas
Vestibular Schwannoma, NF2, Neurofibromatosis 2
EARLY_Phase 12009-06-01
CompletedAllo BMT Using Matched Related/Unrelated Donors With FluBu and HiCY
Lymphoma, Multiple Myeloma, Leukemia
Phase 1 / Phase 22009-05-01
CompletedTopical Application of Sulforaphane-containing Broccoli Sprout Extracts on Radiation Dermatitis
Breast Cancer, Dermatitis
2009-04-15
Active Not RecruitingJohns Hopkins Breast Cancer Program Longitudinal Repository
Breast Cancer, Benign Breast Disease
2009-04-01
CompletedStudy to Evaluate the Effect of Sulforaphane in Broccoli Sprout Extract on Breast Tissue
Breast Cancer
Phase 22009-04-01
CompletedIpilimumab +/- Vaccine Therapy in Treating Patients With Locally Advanced, Unresectable or Metastatic Pancreat
Pancreatic Cancer
Phase 12009-02-01
TerminatedR-ICE and High-Dose Cyclophosphamide With PET/CT for Diffuse Large B-Cell Non-Hodgkin's Lymphoma
Non-Hodgkin's Lymphoma
Phase 22009-01-01
CompletedHypofractionated Adaptive Image-Guided Radiation Therapy for Localized Adenocarcinoma of the Prostate
Prostate Cancer
Phase 22008-12-22
CompletedSafety Study of Bone Marrow Transplant Using Mismatched Tissue Followed by Chemotherapy
MDS, Leukemias, Lymphomas
Phase 22008-12-01
CompletedTrastuzumab, Cyclophosphamide, and Vaccine Therapy in Treating Patients With High-Risk or Metastatic Breast Ca
Breast Cancer
Phase 22008-12-01
TerminatedPhase II Study of Itraconazole and Pemetrexed in Patients With Previously Treated Non-Squamous NSCLC
Recurrent Non Small Cell Lung Cancer
Phase 22008-11-01
CompletedVaccine Therapy With or Without Imiquimod in Treating Patients With Grade 3 Cervical Intraepithelial Neoplasia
Cervical Cancer, Precancerous Condition, HPV Disease
Phase 12008-11-01
TerminatedPhase II Study of Doxorubicin and Avastin® in Sarcoma.
Sarcoma, Soft Tissue Sarcoma
Phase 22008-09-01
CompletedVaccine Therapy With or Without Cyclophosphamide in Treating Patients Undergoing Chemotherapy and Radiation Th
Pancreatic Cancer
Phase 22008-07-02
TerminatedNon-Myeloablative Bone Marrow Transplant for Patients With Sickle Cell Anemia and Other Blood Disorders
Sickle Cell Disease
Phase 22008-06-23
CompletedScreening for Early Pancreatic Neoplasia (Cancer of the Pancreas Screening or CAPS4 Study)
Early Pancreatic Neoplasia, Familial Pancreatic Neoplasia
2008-06-01
CompletedMagnetic Acupressure in Reducing Pain in Cancer Patients Undergoing Bone Marrow Aspiration and Biopsy
Hematopoietic/Lymphoid Cancer, Pain
N/A2008-05-07
Active Not RecruitingCarboplatin and Nab-Paclitaxel With or Without Vorinostat in Treating Women With Newly Diagnosed Operable Brea
Breast Cancer
Phase 22008-05-01
TerminatedValproic Acid in Treating Patients With Progressive, Non-Metastatic Prostate Cancer
Prostate Cancer
Phase 22008-05-01
CompletedTrial of Partial Breast Irradiation With Various Concurrent Chemotherapy Regimens
Breast Cancer
N/A2008-04-01
TerminatedStandard Pain Control or Intrathecal Therapy in Controlling Pain in Patients With Locally Advanced, Unresectab
Pain, Pancreatic Cancer
N/A2008-03-01
CompletedStudy of Colon GVAX and Cyclophosphamide in Patients With Metastatic Colorectal Cancer
Colorectal Cancer, Metastatic Cancer
Phase 12008-03-01
TerminatedTestosterone Gel in Preventing Weakness Caused by Steroid Therapy in Men With Glioma
Brain and Central Nervous System Tumors, Musculoskeletal Complications
N/A2008-01-01
TerminatedTransplantation of Umbilical Cord Blood Following Chemotherapy for Blood Cancers
Acute Myeloid Leukemia, Leukemia, Lymphoblastic, Acute, Leukemia, Bilineage, Acute
Phase 1 / Phase 22007-12-20
CompletedActivated White Blood Cells With ASCT for Newly Diagnosed Multiple Myeloma
Multiple Myeloma and Plasma Cell Neoplasm
Phase 1 / Phase 22007-11-01
CompletedHydroxychloroquine, Radiation, and Temozolomide Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Brain and Central Nervous System Tumors
Phase 1 / Phase 22007-10-29
TerminatedInterferon Alfa and Interleukin-6 in Treating Patients With Recurrent Multiple Myeloma
Multiple Myeloma and Plasma Cell Neoplasm
EARLY_Phase 12007-10-01
TerminatedStudying Fentanyl in Patients With Cancer
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia
2007-10-01
TerminatedPhase I Dose-Escalation Trial of Clofarabine Followed by Escalating Doses of Fractionated Cyclophosphamide in
Myelodysplastic Syndrome, Acute Myeloid Leukemia, Myeloproliferative Disorders
Phase 12007-09-01
TerminatedVaccine Therapy in Treating Patients With Myelodysplastic Syndromes
Myelodysplastic Syndromes
EARLY_Phase 12007-09-01
TerminatedFreehand Ultrasound Elasticity Imaging in Liver Surgery
Liver Tumors
2007-09-01
CompletedAssessment of Liver Cancer Response to TACE Using MultiHance-Enhanced MRI.
Hepatocellular Carcinoma
N/A2007-09-01
CompletedUltrasound Based Localization of Lumpectomy Bed in Anatomical Coordinate System
Resected Breast Cancer, Breast Cancer
2007-08-01
CompletedIdentifying Circulating Breast Cancer Cells in Women With Metastatic Breast Cancer
Breast Cancer
2007-08-01
TerminatedInfrastructure for Developing Gastrointestinal Cancer Prognostic and Predictive Markers
Gastrointestinal Cancer
2007-08-01
CompletedSafety and Efficacy Study of I-131 Tositumomab in Patients With Relapsed/Refractory Hodgkin's Lymphoma
Hodgkin's Disease
Phase 1 / Phase 22007-06-01
TerminatedCyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer
Cancer
EARLY_Phase 12007-06-01
CompletedA Trial of Tadalafil in Patients With Squamous Cell Carcinoma of the Upper Aero Digestive Tract
Head and Neck Squamous Cell Carcinoma
Phase 22007-05-08
TerminatedSafety Study to Determine the Appropriate Dose of Antibody Against Tumor Cells to Best Target Patients With Pa
Pancreatic Cancer
EARLY_Phase 12007-05-01
CompletedHigh-Dose Cyclophosphamide for Steroid Refractory GVHD
Graft Versus Host Disease
Phase 22007-05-01
CompletedCetuximab in Treating Patients With Precancerous Lesions of the Upper Aerodigestive Tract
Head and Neck Cancer, Precancerous Condition
Phase 22007-05-01
CompletedMusculoskeletal Outcomes After Bone Marrow Transplant
Survivors of Bone Marrow Transplant, Autologous and Allogeneic
2007-05-01
CompletedOral HPV Infection in Young Men
Head and Neck Cancer, Infection, Precancerous Condition
2007-05-01
TerminatedVaccine Therapy in Treating Patients Who Have Received First-Line Therapy for Hodgkin's Lymphoma
Lymphoma
Phase 1 / Phase 22007-04-01
TerminatedVaccine Therapy With or Without Donor Lymphocyte Infusion in Treating Patients With Acute Myeloid Leukemia, Ac
Leukemia, Multiple Myeloma and Plasma Cell Neoplasm
Phase 12007-04-01
CompletedGossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed
Brain and Central Nervous System Tumors
Phase 12007-02-01
CompletedMaking Decisions About Participating in a Cancer Clinical Trial for Patients With Stage II, Stage III, or Stag
Colorectal Cancer, Pancreatic Cancer, Psychosocial Effects of Cancer and Its Treatment
N/A2007-01-19
CompletedLenalidomide and Vaccine Therapy in Treating Patients With Relapsed or Refractory Multiple Myeloma
Multiple Myeloma and Plasma Cell Neoplasm
Phase 22007-01-01
CompletedDNA in Predicting Response After Systemic Therapy in Women With Metastatic Breast Cancer
Breast Cancer
2007-01-01
TerminatedMRX, Radiation, and Chemotherapy for Patients With Resected Squamous Cell Carcinoma of the Head and Neck
Squamous Cell Carcinoma, Head and Neck Cancer, Resected Head and Neck Cancer
Phase 12007-01-01
CompletedTetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade Glioma
Brain and Central Nervous System Tumors
Phase 1 / Phase 22007-01-01
CompletedPattern of Cell Death Following Neoadjuvant Therapy for Metastatic Colon Cancer
Metastatic Colorectal Cancer
2006-12-01
WithdrawnPlastic Stents Compared With Metal Stents in Treating Patients With Malignant Dysphagia Caused by Esophageal C
Esophageal Cancer, Gastrointestinal Complications
N/A2006-12-01
TerminatedPharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Thera
Brain and Central Nervous System Tumors, Thrombocytopenia
2006-11-11
CompletedBexarotene and GM-CSF in Treating Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia
Leukemia, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases
Phase 22006-11-01
CompletedProspective Assessment of Symptoms and Quality of Life in Rectal Cancer Patients Receiving Chemo-Radiotherapy
Rectal Cancer
2006-11-01
CompletedTumor Tissue Analysis in Patients Receiving Imatinib Mesylate for Malignant Glioma
Brain and Central Nervous System Tumors
Phase 12006-10-12
TerminatedCyclophosphamide Plus T-Cell Transplantation for Patients With Hematologic Malignancies
Leukemia, Myelodysplastic Syndromes
Phase 12006-10-01
WithdrawnStudy of Mitomycin-C in Patients With Advanced or Recurrent Pancreatic Cancer With Mutated BRCA2 Gene
Pancreatic Cancer
Phase 22006-10-01
TerminatedEverolimus in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Previous
Colorectal Cancer
Phase 22006-10-01
CompletedAdjuvant GVAX Vaccine Therapy in Patients With Pancreatic Cancer
Pancreatic Cancer
Phase 22006-09-11
CompletedInterferon and GM-CSF Compared With Imatinib Mesylate and Vaccine Therapy in Patients With Chronic Phase CML o
Leukemia
Phase 22006-09-01
CompletedLaboratory Test in Predicting Response to Erlotinib in Patients With Relapsed Metastatic or Unresectable Non-S
Lung Cancer
Phase 22006-09-01
CompletedTrastuzumab, Cyclophosphamide, and an Allogeneic GM-CSF-secreting Breast Tumor Vaccine for the Treatment of HE
Breast Neoplasms
Phase 22006-09-01
CompletedSirolimus Before Surgery in Treating Patients With Advanced Localized Prostate Cancer
Prostate Cancer
Phase 1 / Phase 22006-08-01
WithdrawnCyclophosphamide and Rituximab Followed By Vaccine Therapy in Treating Patients With Chronic Lymphocytic Leuke
Leukemia
Phase 22006-08-01
CompletedStudy of 2 Different Doses of Revlimid in Biochemically Relapse Prostate Cancer
Prostate Cancer
Phase 1 / Phase 22006-07-20
CompletedIodine I 131 Tositumomab or Yttrium Y 90 Ibritumomab Tiuxetan in Treating Patients With Non-Hodgkin's Lymphoma
Lymphoma
2006-07-01
TerminatedOne Time Injection of Bacteria to Treat Solid Tumors That Have Not Responded to Standard Therapy
Tumors
Phase 12006-07-01
TerminatedProtein Biomarker in Hepatocellular Carcinoma
Normal Volunteers, Hepatitis, Liver Cirrhosis
2006-06-20
CompletedTransitoriness in Cancer Patients, Psychosocial Issues in Cancer Care
Lung Cancer, Gastrointestinal Cancers
2006-06-01
CompletedEpidermal Growth Factor Receptor Mutations in the Blood of Patients With Advanced Non-Small Cell Lung Cancer
Lung Cancer
2006-06-01
CompletedSimvastatin and Anastrozole in Treating Postmenopausal Women With Ductal Carcinoma In Situ or Invasive Breast
Breast Cancer
Phase 22006-06-01
CompletedSpect Analysis of Cardiac Perfusion Changes After Whole Breast/Chest Wall Radiation Therapy With ABC
Breast Neoplasms, Carcinoma, Ductal, Adenocarcinoma
N/A2006-06-01
CompletedStudy of Robotic Template Guidance for Needle Placement in Transperineal Prostate Brachytherapy
Prostate Cancer
N/A2006-06-01
CompletedEffect of Surgery, Radiation Therapy, Chemotherapy, and Hormone Therapy on Biomarkers in Women With Stage I, S
Breast Cancer
2006-05-01
CompletedMelanoma Biomarker Study
Metastatic Melanoma
2006-05-01
CompletedPhase 2 Study of Rituximab-ABVD in Classical Hodgkin Lymphoma
Lymphoma
Phase 22006-05-01
TerminatedIodine I 131 in Treating Patients With Thyroid Cancer
Head and Neck Cancer
N/A2006-04-01
CompletedChemoRT With Adjuvant Chemo in Pancreatic Cancer (TARCEVA)
Pancreatic Cancer
Phase 22006-03-16
CompletedSimvastatin in Preventing a New Breast Cancer in Women at High Risk for a New Breast Cancer
Breast Cancer
Phase 22006-03-01
TerminatedModafinil in Opioid Induced Sedation
Cancer, Pain
Phase 32006-01-01
CompletedNeo-adjuvant Chemotherapy in Locally Advanced Gastric Cancer
Stage T3-4NxM0 Gastric Cancer
Phase 22006-01-01
CompletedRadiation Therapy and Temozolomide Followed by Temozolomide and Poly ICLC in Treating Patients With Newly Diag
Glioblastoma Multiforme
Phase 22006-01-01
CompletedScreening for Lung Cancer in the HIV Patient
Lung Cancer in the HIV Patient, HIV Infections, HIV Seropositivity
2006-01-01
TerminatedIdentification of a Screening Tool and Treatment of Lymphedema Secondary to the Management of Breast Cancer St
Breast Cancer, Lymphedema
N/A2006-01-01
CompletedVaccine Therapy, Cyclophosphamide, and Cetuximab in Treating Patients With Metastatic or Locally Advanced Panc
Pancreatic Cancer
Phase 22005-12-01
CompletedCapecitabine as Second-Line Therapy in Treating Patients With Stage IV Pancreatic Cancer Who Have the Thymidyl
Pancreatic Cancer
Phase 22005-12-01
CompletedClofarabine and Cyclophosphamide in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myel
Chronic Myeloproliferative Disorders, Leukemia, Myelodysplastic/Myeloproliferative Diseases
Phase 12005-11-01
CompletedLiposomal Doxorubicin Before Mastectomy in Treating Women With Invasive Breast Cancer
Breast Cancer
Phase 12005-11-01
CompletedRituximab and Cyclophosphamide Followed by Vaccine Therapy in Treating Patients With Relapsed Hodgkin Lymphoma
Lymphoma
Phase 1 / Phase 22005-11-01
TerminatedInfrared Thermography in Finding Skin Lesions in Patients With Kaposi's Sarcoma
Sarcoma
N/A2005-10-03
TerminatedIndividualized Drug Treatment for Treating Patients With Pancreatic Cancer
Pancreatic Cancer
Phase 22005-10-01
TerminatedStudy of PET Scans and Serotonin in Hot Flashes Treatment
Hot Flashes
N/A2005-10-01
TerminatedEx Vivo Expansion of Mafosfamide Purged CD34+ Cells in Patients With Acute Leukemia
Leukemia
Phase 12005-10-01
TerminatedLiposomal Doxorubicin (Lipo-Dox) in Patients With Brain Metastasis From Breast Cancer
Breast Cancer
Phase 22005-09-01
TerminatedRituximab, Temozolomide, and Methylprednisolone in Treating Patients With Recurrent Primary CNS Non-Hodgkin's
Lymphoma
Phase 22005-09-01
CompletedLomustine in Treating Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
Lung Cancer
Phase 22005-07-01
CompletedGemcitabine and Carboplatin Followed by Paclitaxel in Treating Patients With Stage III or Stage IV Non-Small C
Lung Cancer
Phase 22005-07-01
CompletedErlotinib in Treating Patients With Metastatic and/or Recurrent Head and Neck Cancer
Head and Neck Cancer
Phase 22005-07-01
CompletedCombination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Burkitt's Lymphoma or Leukemi
Leukemia, Lymphoma
Phase 22005-07-01
TerminatedRituximab and GM-CSF in Treating Patients With Chronic Lymphocytic Leukemia
Leukemia
Phase 22005-07-01
CompletedCollecting and Storing Samples of Blood From Patients With Pancreatic Cancer and Healthy Participants
Pancreatic Cancer
2005-05-01
TerminatedPaclitaxel, Cisplatin, Gefitinib, and Radiation Therapy Followed by Surgery and Gefitinib in Treating Patients
Esophageal Cancer
Phase 22005-04-01
CompletedRisk Factors for Developing a Blood Clot in Patients Who Are Undergoing Cancer Treatment for Newly Diagnosed G
Brain and Central Nervous System Tumors, Thromboembolism
2005-04-01
CompletedTumor DNA and MRI/CT Scan Findings in Patients With Grade III or Grade IV Malignant Glioma
High Grade Glioma
N/A2005-04-01
TerminatedTemozolomide During and After Radiation Therapy in Treating Patients Who Have Undergone Previous Surgery and P
Brain and Central Nervous System Tumors
Phase 22005-02-15
CompletedStudy of Image-guided Dosimetry for Interstitial Prostate Brachytherapy
Locally Confined Adenocarcinoma of the Prostate
Phase 12005-02-01
CompletedRituximab, Cyclophosphamide, and Pegfilgrastim in Treating Patients With Leukemia or Non-Hodgkin's Lymphoma
Leukemia, Lymphoma
Phase 22005-01-01
CompletedSirolimus in Treating Patients With Advanced Pancreatic Cancer
Pancreatic Cancer
Phase 22005-01-01
CompletedBroccoli Sprout Extract in Preventing Lung Cancer in Smokers
Lung Cancer
N/A2005-01-01
CompletedStudy of Docetaxel +153 Sm-EDTMP in Patients With Hormone-Refractory Prostate Cancer
Prostate Cancer
Phase 12004-12-01
CompletedSirolimus in Treating Patients With Metastatic or Unresectable Solid Tumors
Unspecified Adult Solid Tumor, Protocol Specific
Phase 12004-12-01
CompletedRituximab and Cyclophosphamide in Treating Patients With High Risk, Refractory, or Relapsed Multiple Myeloma
Multiple Myeloma and Plasma Cell Neoplasm
Phase 22004-12-01
CompletedErlotinib, Paclitaxel, and Carboplatin in Treating Patients With Stage III, Stage IV, or Recurrent Non-Small C
Lung Cancer
Phase 22004-11-01
CompletedArsenic Trioxide and Radiation Therapy in Treating Young Patients With Newly Diagnosed Gliomas
Brain and Central Nervous System Tumors
Phase 12004-11-01
TerminatedIrinotecan in Treating Patients With Metastatic or Inoperable Thyroid Cancer
Head and Neck Cancer
Phase 22004-11-01
CompletedSamarium Sm 153 and Stem Cell Transplant Followed By Radiation Therapy Patients With Osteosarcoma
Sarcoma
Phase 22004-10-01
CompletedCombination Chemotherapy in Treating Patients With Acute Promyelocytic Leukemia
Leukemia
Phase 22004-10-01

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