Clinical Trials Directory

Trials / Completed

CompletedNCT02856100

Comparison of PSMA-based 18F-DCFPyL PET/CT to Conventional Imaging in the Evaluation of Patients With Castration-Resistant Prostate Cancer

Status
Completed
Phase
Study type
Observational
Enrollment
18 (actual)
Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Academic / Other
Sex
Male
Age
18 Years – 120 Years
Healthy volunteers
Not accepted

Summary

We intend to validate 18F-DCFPyL for imaging patients with metastatic, castrate-resistant PCa (CRPC), so that it may be used to full advantage in supporting existing and emerging therapies for a spectrum of patients suffering from PCa. In this study we will image patients with CRPC undergoing second-line anti-androgen therapy (enzalutamide or abiraterone) using 18F-DCFPyL-PET/CT for detection of metastases and therapeutic monitoring, with correlation to standard-of-care conventional imaging modalities (CIM) (CT, bone scan) and clinical follow-up.

Conditions

Interventions

TypeNameDescription
DRUG18F DCFPyL- Radiopharmaceutical

Timeline

Start date
2016-08-03
Primary completion
2019-01-01
Completion
2020-01-01
First posted
2016-08-04
Last updated
2020-05-07

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT02856100. Inclusion in this directory is not an endorsement.