Clinical Trials Directory

Trials / Terminated

TerminatedNCT03043794

Study of Stereotactic Radiotherapy for Breast Cancer

A Phase II Study of Preoperative Single Fraction Stereotactic Body Radiotherapy to the Intact Breast in Early Stage Low Risk Breast Cancer: Analysis of Radiation Response

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
4 (actual)
Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Academic / Other
Sex
Female
Age
50 Years – 100 Years
Healthy volunteers
Not accepted

Summary

This is a Phase II trial of preoperative stereotactic radiation to the breast for low risk breast cancer.

Detailed description

This is a single arm phase II study design, evaluating the pathologic response (primary endpoint) as well as toxicity, cosmetic outcome, quality of life, and translational correlates (secondary endpoints) to pre-operative stereotactic body radiotherapy (SBRT) to intact breast tumors in patients with hormone-receptor positive early stage breast cancer.

Conditions

Interventions

TypeNameDescription
RADIATIONStereotactic Body Radiation Therapy SBRTStereotactic Body Radiation Therapy to the breast to 21 Gy

Timeline

Start date
2017-08-01
Primary completion
2021-10-20
Completion
2023-10-22
First posted
2017-02-06
Last updated
2024-09-19
Results posted
2024-09-19

Locations

2 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03043794. Inclusion in this directory is not an endorsement.