| Not Yet Recruiting | Prospective Lifespan Cohort of Myocardial Infarction NCT07471763 | Fujian Provincial Hospital | — |
| Recruiting | Advanced NanoTherapies Dual-API DCB to Treat De-Novo and ISR Lesions in Patients With Symptomatic Coronary Art NCT07368933 | Advanced NanoTherapies | N/A |
| Recruiting | Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Depart NCT06860997 | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | N/A |
| Recruiting | LEADERS FREE IV (RCT): BioFreedom™ Ultra vs BioFreedom™ in HBR Patients NCT06657326 | Biosensors Europe SA | N/A |
| Recruiting | Treatment of ACuTe Coronary Syndromes With Low-dose colchICine NCT06215989 | Beijing Anzhen Hospital | N/A |
| Completed | Telehealth Group Counseling and Preventive Care for Women NCT06404515 | Weill Medical College of Cornell University | N/A |
| Recruiting | European Survey of Cardiovascular Disease Prevention, Diabetes and Chronic Kidney Disease (EUROASPIRE VI) NCT06495177 | European Society of Cardiology | — |
| Recruiting | Japanese Coronary Intervention Using Drug Eluting and Perfusion Therapy for Left Main Disease (JDEPTH-LM Regis NCT06436092 | TCROSS Co., Ltd. | — |
| Unknown | Prasugrel Or Ticagrelor De-escalation in NSTE-ACS NCT05779059 | Collegium Medicum w Bydgoszczy | Phase 3 |
| Completed | Incidence, Clinical Characteristics and Outcomes of Unstable Angina in the contempoRary Area. NCT06378333 | University Hospital, Montpellier | — |
| Completed | Evaluation of the LVivo Image Quality Scoring (IQS) NCT05563701 | DiA Imaging Analysis Ltd | — |
| Unknown | Therapeutic Use of Contrast Ultrasound in Acute Coronary Artery Disease NCT04732091 | University of Sao Paulo General Hospital | — |
| Unknown | Evaluation of Safety and Efficacy of Two Ticagrelor-based De-escalation Antiplatelet Strategies in Acute Coron NCT04718025 | Collegium Medicum w Bydgoszczy | Phase 3 |
| Recruiting | A Cohort of Patients Undergoing Percutaneous Coronary Intervention NCT05719545 | Su Guohai | — |
| Recruiting | PRospective Evaluation of Complete Revascularization in Patients With multiveSsel Disease Excluding chroNic To NCT05230446 | Erasmus Medical Center | N/A |
| Active Not Recruiting | Physiology as Guidance to Evaluate the Direct Impact of Coronary Lesion Treatment: The PREDICT Study NCT04929496 | Laval University | N/A |
| Completed | Dapagliflozin Effects on Coronary Calcium and Epicardial Fat Assessed by Cardiotomography NCT05998525 | Hilda Elizabeth Macías Cervantes | Phase 3 |
| Completed | Fecal Microbiota and Monocyte Trained Immunity in CHD Patients With Different hsCRP NCT06562309 | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | — |
| Completed | Pivotal, Single-arm Clinical Trial to Assess the Efficacy and Safety of the MedHub AutocathFFR Software Device NCT04861519 | Medhub Ltd. | — |
| Completed | Prehospital Triage of Patients With Suspected Non-ST-segment Elevation Acute Coronary Syndrome: the TRIAGE-ACS NCT05243485 | Catharina Ziekenhuis Eindhoven | — |
| Unknown | Efficacy and Safety of Wen Xin Granules for the Treatment of Unstable Angina Pectoris NCT04661709 | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | Phase 4 |
| Completed | the PrEsentation, Rationale and Impact of reperFUSION for Acute Coronary Syndromes in Cape Town and the Garden NCT04887571 | University of Cape Town | — |
| Unknown | A Multicenter Study on Early Diagnosis of NSTE-ACS Patients Based on Machine Learning Model NCT04682756 | First Affiliated Hospital of Xinjiang Medical University | — |
| Unknown | The FAST OCT Study NCT04683133 | Erasmus Medical Center | N/A |
| Unknown | Drug Coated Balloon for Side Branch Treatment vs. Conventional Approach in True Bifurcation Coronary Disease: NCT04403048 | Clinical Hospital Center Rijeka | N/A |
| Unknown | CardioSenseSystem Compared Study Regarding Efficacy and Safety in the Monitoring of ECG NCT03610529 | Novosense AB | N/A |
| Withdrawn | A Randomized Trial of Telemetry Compared With Unmonitored Floor Admissions in ED Patients With Low-Risk Chest NCT03906812 | Vanderbilt University Medical Center | N/A |
| Unknown | Post-Revascularization Optimization and PHysiological Evaluation of intermediaTe Lesions NCT05056662 | Catholic University of the Sacred Heart | — |
| Completed | Influence of METHoxyflurane on ANtiplatelet Effect of Ticagrelor in Patients With Unstable Angina Pectoris NCT04442919 | Collegium Medicum w Bydgoszczy | Phase 4 |
| Completed | MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms NCT04231097 | Massachusetts General Hospital | N/A |
| Completed | Study to Gather Information to What Extent Patients Follow the Treatment Regimen of Low-dose Aspirin for Prima NCT04097912 | Bayer | — |
| Completed | Restore EF Observational Study NCT04648306 | Abiomed Inc. | — |
| Unknown | Metformin Continuation Versus Interruption Following Coronary Angiography: a Pilot Randomized Controlled Trial NCT03980990 | University of Saskatchewan | Phase 4 |
| Unknown | Exploring the Mechanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and Computa NCT03591328 | Seoul National University Hospital | — |
| Completed | MBCT Delivered Via Group Videoconferencing for ACS Patients With Elevated Depression Symptoms NCT03878160 | Massachusetts General Hospital | N/A |
| Completed | International Collaboration of Comprehensive Physiologic Assessment NCT03690713 | Seoul National University Hospital | — |
| Completed | Periodontal Disease, Inflammation and Acute Coronary Syndromes NCT03395041 | Cardio Med Medical Center | — |
| Completed | Multiomics and Imaging-based Assessment of Vulnerable Coronary Plaques in Acute Coronary Syndromes NCT03391908 | Cardio Med Medical Center | — |
| Completed | Technology-Based Intervention to Promote Heart Health After Cardiac Rehab (Mobile4Heart) NCT03446313 | University of California, San Francisco | N/A |
| Unknown | PERcutaneouS Coronary intErventions in Patients Treated With Oral Anticoagulant Therapy NCT03392948 | Italian Society of Invasive Cardiology | — |
| Completed | Effectiveness and Safety of a Clinical Assessment and 0h/1h Troponin Rule-Out Protocol NCT03421873 | Ulf Ekelund | — |
| Completed | Safety and Efficacy of LMWH Versus Rivaroxaban in Chinese Patients Hospitalized With Acute Coronary Syndrome NCT03363035 | Second Xiangya Hospital of Central South University | Phase 4 |
| Active Not Recruiting | INsTantenous wavE-Free Ratio-guided PCI Versus Fractional Flow REserve-Guided PCI in rouTine Clinical Practice NCT03338309 | Samsung Medical Center | — |
| Unknown | Evaluation of Short Term Outcome of Different Bifurcation Stenting Techniques at Assuit University Cath. Lab NCT03266289 | MA Abdelreheem | — |
| Unknown | Research on the Clinical Effect of Effective Prescription in Treating Unstable Angina. NCT03171597 | Jun Li | Phase 4 |
| Unknown | Effect of Gualou Xiebai Banxia Decoction With Danshen Decoction in Treating Unstable Angina. NCT03179514 | Jun Li | Phase 4 |
| Unknown | Research on the Clinical Effect of Shuanghe Decoction in Treating Unstable Angina. NCT03179527 | Jun Li | Phase 4 |
| Unknown | Research on the Clinical Effect of Xuefu Zhuyu Decoction in Treating Unstable Angina. NCT03179618 | Jun Li | Phase 4 |
| Completed | Comparison Between Ticagrelor Versus Very Low Dose Rivaroxaban With Clopidogrel NCT03481257 | Seoul National University Hospital | — |
| Unknown | To Evaluate Safety and Efficacy of CGBIO Stent Compared to Biomatrix Flex Stent NCT03089450 | CGBio Inc. | N/A |
| Unknown | Efficacy and Safety of Xuesaitong Soft Capsule for Coronary Heart Disease Unstable Angina NCT03083119 | Jie Wang | Phase 2 |
| Completed | Comparison of Left and Right Transradial Approach for CAG and PCI NCT03389503 | Wonju Severance Christian Hospital | N/A |
| Unknown | Efficacy and Safety of Salvianolate Injection in Elderly Patients With Unstable Angina Pectoris NCT03037047 | Green Valley Group of China | Phase 4 |
| Completed | Cardiac Care Solution for Coronary Disease Follow up NCT03565978 | Peking University First Hospital | N/A |
| Withdrawn | COMBO-Stent in Patients on Chronic Anticoagulant Therapy (COSTA) COSTA-Bleed and COSTA-Outcome Trials NCT02723981 | IHF GmbH - Institut für Herzinfarktforschung | Phase 4 |
| Completed | Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Gener NCT02601157 | Seoul National University Hospital | Phase 4 |
| Completed | Safety and Effectiveness Evaluation of COBRA PzF Coronary Stent System: A Post Marketing Observational Registr NCT03103620 | CeloNova BioSciences, Inc. | — |
| Completed | Assessment of Diagonal Branch Territory NCT03935542 | Bon-Kwon Koo | — |
| Unknown | Impact of Low Frame Rate Fluoroscopy and Cine-angiography on Reducing Operator and Patient Dose NCT02574949 | University Health Network, Toronto | N/A |
| Unknown | A Registry Study on Genetics and Biomarkers of Acute Coronary Syndrome NCT03752515 | Beijing Institute of Heart, Lung and Blood Vessel Diseases | — |
| Completed | Patient and Provider Assessment of Lipid Management Registry NCT02341664 | Duke University | — |
| Unknown | PatientSpot Formerly Known as ArthritisPower NCT03840928 | Global Healthy Living Foundation | — |
| Withdrawn | Acute Coronary Syndrome Sri Lanka Audit Project NCT02893280 | University of Colombo | — |
| Completed | Drug Coated Balloon Compared to Bare Metal Stent for de Novo Coronary Artery Lesions NCT02456402 | Ulsan University Hospital | N/A |
| Unknown | Optimal Lesion Preparation With Non-compliant Balloons Before Implantation Of Bioresorbable Scaffolds (OPreNBi NCT02468960 | SIS Medical AG | N/A |
| Completed | Vasoactive and Anti-inflammatory Effects of Prasugrel in Acute Coronary Syndrome NCT01774838 | University of Cologne | Phase 3 |
| Unknown | Appropriateness of Coronary Angioplasty in PAtients With isCHEmic Heart Disease NCT02748603 | Italian Society of Invasive Cardiology | — |
| Unknown | BioFreedom US IDE Feasibility Trial NCT02131142 | Biosensors Europe SA | Phase 2 / Phase 3 |
| Completed | Safety and Efficacy of CMX-2043 for Protection of the Heart and Kidneys in Subjects Undergoing Coronary Angiog NCT02103959 | Ischemix, LLC | Phase 2 |
| Unknown | Assessment of Coronary Flow Reserve by Doppler Flow WIre in Patients With Acute Coronary Syndrome Undergoing P NCT02032303 | Azienda Policlinico Umberto I | Phase 4 |
| Unknown | Assessment of Coronary Flow Reserve by Doppler Flow Wire in Patients With Acute Coronary Syndrome Undergoing P NCT02032290 | Azienda Policlinico Umberto I | Phase 4 |
| Completed | Efficacy of Vitamin E in Preventing Contrast-Induced Acute Kidney Injury Following Coronary Angiography NCT02070679 | Urmia University of Medical Sciences | Phase 3 |
| Unknown | Understanding the Role of Autoimmune Disorders on the Initial Presentation of Cardiovascular Disease NCT02062021 | University College, London | — |
| Completed | Ethnicity and Onset of Cardiovascular Disease: A CALIBER Study NCT02176174 | University College, London | — |
| Completed | Coronary and Structural Interventions Ulm - Bioresorbable Vascular Scaffold NCT02162056 | University of Ulm | N/A |
| Completed | Comparison of Saphenous Vein Graft Harvested From Upper Versus Lower Leg in Coronary Artery Bypass Grafting NCT01974492 | Seoul National University Hospital | N/A |
| Completed | Comparison of the Angiographic Result of the Orsiro Hybrid Stent With Resolute Integrity Stent NCT01826552 | Seoul National University Bundang Hospital | Phase 4 |
| Unknown | Quantification and Description of the Increase in Serum Troponin Following Acute Coronary Syndrome NCT01698021 | Université de Sherbrooke | — |
| Completed | Ticagrelor or Prasugrel Versus Clopidogrel in Elderly Patients With an Acute Coronary Syndrome and a High Blee NCT02317198 | St. Antonius Hospital | Phase 4 |
| Completed | Investigation of the Role of Hemodynamics in Re-stenosis of CABG Patients NCT02791087 | National Heart Centre Singapore | — |
| Unknown | Atorvastatin for Reduction of Myocardial Damage During Angiography and Its Mechanism Associated With IMR NCT01761656 | Central South University | Phase 2 |
| Completed | Low Rate Fluoroscopy to Reduce Radiation Dose During Coronary Angiography and Intervention NCT01990924 | Laval University | N/A |
| Completed | Comparison Between Lidocaine, Dexmedetomidine, and Their Combined Infusion in Subjects Undergoing Coronary Art NCT01688648 | Samsung Medical Center | N/A |
| Completed | The Impact of Gratitude on Biology and Behavior in Persons With Heart Disease NCT01709669 | Massachusetts General Hospital | — |
| Terminated | Patients With High-risk Acute Coronary Syndrome Without ST-segment Elevation NCT01356992 | Eurofarma Laboratorios S.A. | Phase 3 |
| Unknown | The Study of MicroRNA Genomics of Blood Stasis Syndrome and of Coronary Heart Disease NCT01615003 | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | Phase 2 |
| Completed | Shortened Aggrastat® Versus Integrilin in Percutaneous Coronary Intervention NCT01522417 | Medicure | Phase 2 |
| Completed | Conservative Non-Invasive Versus Routine Invasive Management in Coronary Artery Bypass Surgery Patients with N NCT01895751 | NHS National Waiting Times Centre Board | Phase 4 |
| Completed | HDL-C in Cardiac Syndrome X NCT02095964 | Bursa Yuksek Ihtisas Training and Research Hospital | — |
| Completed | Prospective, Single-arm, Multicenter Study for Evaluation the Safety and Effectiveness of the ALEX Stent in a NCT01637012 | Balton Sp.zo.o. | Phase 4 |
| Completed | Clinical Performance of CRE8 Drug Eluting Stent in All Comer Population NCT01556126 | CID - Carbostent & Implantable Devices | N/A |
| Unknown | Heart Rate and Initial Presentation of Cardiovascular Diseases (Caliber) NCT01947361 | University College, London | — |
| Unknown | Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study NCT01937065 | University College, London | — |
| Completed | Optical Coherence Tomography Comparison of Neointimal Coverage Between CRE8 DES and BMS NCT01543373 | CID - Carbostent & Implantable Devices | N/A |
| Unknown | Randomized Controlled Study of the Traditional Percutaneous Coronary Intervention and Intervention Using Optic NCT01869842 | Yonsei University | N/A |
| Completed | Acute Coronary Syndrome and Care-Seeking Delay: A Web Based Behavioral Study NCT01407146 | Yale University | — |
| Completed | Clearance Of Mucus In Stents (COMIS) NCT01370278 | M.D. Anderson Cancer Center | N/A |
| Completed | Comparison of Drug Eluting Balloon and Drug Eluting Stent NCT01539603 | Seoul National University Bundang Hospital | Phase 2 |
| Completed | Study Evaluating How Patients With Acute Coronary Syndrome Are Managed During 2 Years After Discharge NCT01171404 | AstraZeneca | — |
| Completed | Usefulness of High-frequency QRS Analysis in the Evaluation of Patients With Chest Pain NCT01185899 | Ori Galante | — |
| Unknown | Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome NCT01372839 | Xijing Hospital | Phase 4 |
| Terminated | Study Comparing CT Scan and Stress Test in Patients With Known Coronary Artery Disease Hospitalized for Chest NCT01106612 | Montefiore Medical Center | N/A |
| Terminated | Prevalence of Sleep Disordered Breathing NCT01011647 | GE Healthcare | — |
| Completed | CORonary Diet Intervention With Olive Oil and Cardiovascular PREVention NCT00924937 | Hospital Universitario Reina Sofia de Cordoba | N/A |
| Completed | International Randomized Comparison Between DES Limus Carbostent and Taxus DES in the Treatment of De-novo Cor NCT01373502 | CID - Carbostent & Implantable Devices | N/A |
| Completed | Myocardial Ischemia and Transfusion Pilot NCT01167582 | Rutgers, The State University of New Jersey | Phase 3 |
| Completed | Comparative Study of ALX-0081 Versus GPIIb/IIIa Inhibitor in High Risk Percutaneous Coronary Intervention (PCI NCT01020383 | Ablynx, a Sanofi company | Phase 2 |
| Completed | An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome NCT00809965 | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Phase 3 |
| Unknown | Dual Antiplatelet Therapy Tailored on the Extent of Platelet Inhibition NCT00774475 | University of Florence | Phase 3 |
| Completed | Study Comparing CT Scan and Stress Test in Diagnosing Coronary Artery Disease in Patients Hospitalized for Che NCT00705458 | Montefiore Medical Center | N/A |
| Completed | Drug-eluting Balloon in Bifurcations Trial NCT00857441 | UMC Utrecht | Phase 2 / Phase 3 |
| Terminated | A COMparison Between PAClitaxel-coated Balloon and pacliTaxel-eluting Stent in the Treatment of In-Stent Reste NCT01204320 | Ospedale San Donato | Phase 4 |
| Unknown | Coronary Computed Tomographic Angiography in Emergency Department Chest Pain Patients at Intermediate Risk of NCT00473863 | Vancouver General Hospital | Phase 3 |
| Terminated | Ischemia Driven Enoxaparin Therapy in ACS Presenting as Low Risk (IDEAL) NCT00518245 | Canadian Heart Research Centre | Phase 4 |
| Completed | Detection of Coronary Vulnerable Plaque With Contrast-enhanced Magnetic Resonance Imaging NCT00984776 | Maastricht University Medical Center | N/A |
| Completed | A Trial of Everolimus-eluting Stents and Paclitaxel-eluting Stents for Coronary Revascularization in Daily Pra NCT01016041 | Maasstad Hospital | Phase 3 |
| Withdrawn | Intravenous Isosorbide Dinitrate Versus Sublingual Isosorbide Dinitrate for the Relief of Acute Anginal Episod NCT00337116 | Soroka University Medical Center | Phase 4 |
| Completed | Risk Stratification of Non ST Elevation ACS With Computed Tomographic Angiography (REACT) NCT00449826 | Ottawa Heart Institute Research Corporation | N/A |
| Terminated | The Ischemia Modified Albumin In Diagnosing Ischemic New Events NCT00355992 | Inverness Medical Innovations | — |
| Completed | Diagnosis and Treatment of Acute Coronary Syndrome in the ED & the Impact of Rapid Bedside cTnl on Outcome. NCT00276432 | Mayo Clinic | Phase 4 |
| Terminated | Serp-1 for the Treatment of Acute Coronary Syndrome NCT00243308 | Viron Therapeutics Inc | Phase 2 |
| Completed | Evaluation of an Introductory Videotape Intervention to Improve Cardiac Rehabilitation Participation NCT00372671 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Phase 3 |
| Completed | Early Versus Delayed Timing of Intervention in Patients With Acute Coronary Syndromes NCT00552513 | Population Health Research Institute | N/A |
| Completed | MMP Polymorphisms and Acute Coronary Syndromes NCT00484406 | University of Trieste | — |
| Completed | Pilot Study of Hemoglobin Based Oxygen Therapeutics in Elective Coronary Revascularization NCT00317512 | Biopure Corporation | Phase 2 |
| Completed | RRISC Study: Reduction of Restenosis In Saphenous Vein Grafts With Cypher Sirolimus-Eluting Stent. NCT00263263 | Antwerp Cardiovascular Institute Middelheim | Phase 2 |
| Completed | Comparison of Angiomax Versus Heparin in Acute Coronary Syndromes (ACS) NCT00093158 | The Medicines Company | Phase 3 |
| Unknown | ARISE - Aggressive Reduction of Inflammation Stops Events NCT00066898 | AtheroGenics | Phase 3 |
| Completed | PROTECT-TIMI 30 Trial NCT00250471 | Millennium Pharmaceuticals, Inc. | Phase 3 |
| Completed | Improving Cardiac Rehabilitation Participation in Women and Men NCT00336830 | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | Phase 3 |
| Completed | SYNERGY: Open Study of Enoxaparin Versus Unfractionated Heparin in Patients With Acute Coronary Syndromes NCT00043784 | Sanofi | Phase 3 |
| Unknown | Differential Effects of Lipids on Cardiovascular Diseases: A CALIBER Study NCT01687686 | University College, London | — |
| Completed | Bupropion for Hospitalized Smokers With Acute Cardiovascular Disease NCT00181818 | Massachusetts General Hospital | Phase 4 |
| Unknown | Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study NCT03425305 | University College, London | — |
| Completed | DANish Multicenter STENT Trial NCT00139802 | Rigshospitalet, Denmark | Phase 4 |
| Completed | Risk Factors in the Initial Presentation of Specific Cardiovascular Disease Syndromes NCT01804439 | University College, London | — |
| Unknown | The Role of Alcohol Consumption in the Aetiology of Different Cardiovascular Disease Phenotypes: a CALIBER Stu NCT01864031 | University College, London | — |
| Withdrawn | Aggrastat Truncated Length Against Standard Therapies in Percutaneous Coronary Intervention NCT01245725 | Medicure | Phase 3 |