| Terminated | RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant NCT04525014 | EpicentRx, Inc. | Phase 1 |
| Completed | MORAb-004 in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma NCT01748721 | Morphotek | Phase 1 |
| Terminated | Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With NCT01987596 | Barbara Ann Karmanos Cancer Institute | Phase 3 |
| Completed | Sirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed By Surgery NCT01791088 | University of Chicago | Phase 1 |
| Terminated | Positron Emission Tomography/Magnetic Resonance Imaging in Patients NCT01557881 | Case Comprehensive Cancer Center | N/A |
| Completed | Acupressure in Controlling Nausea in Young Patients Receiving Highly Emetogenic Chemotherapy NCT01346267 | University of South Florida | N/A |
| Completed | Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma NCT01273090 | Children's Oncology Group | Phase 1 |
| Completed | Supersaturated Calcium Phosphate Rinse in Preventing Oral Mucositis in Young Patients Undergoing Autologous or NCT01305200 | Children's Oncology Group | Phase 3 |
| Completed | Intensity-Modulated Radiation Therapy in Treating Younger Patients With Lung Metastases NCT01586104 | Ann & Robert H Lurie Children's Hospital of Chicago | N/A |
| Completed | MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia NCT01231919 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Viral Therapy in Treating Young Patients With Relapsed or Refractory Solid Tumors NCT01240538 | National Cancer Institute (NCI) | Phase 1 |
| Completed | INCB18424 in Treating Young Patients With Relapsed or Refractory Solid Tumor, Leukemia, or Myeloproliferative NCT01164163 | Children's Oncology Group | Phase 1 |
| Completed | Temsirolimus, Irinotecan Hydrochloride, and Temozolomide in Treating Younger Patients With Relapsed or Refract NCT01141244 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC) NCT01126346 | Wake Forest University Health Sciences | N/A |
| Completed | Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Canc NCT01053494 | Wake Forest University Health Sciences | N/A |
| Terminated | Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS T NCT01088763 | National Cancer Institute (NCI) | Phase 1 |
| Terminated | Temsirolimus and Valproic Acid in Treating Young Patients With Relapsed Neuroblastoma, Bone Sarcoma, or Soft T NCT01204450 | UNC Lineberger Comprehensive Cancer Center | Phase 1 |
| Completed | AT9283 in Children and Adolescents With Relapsed and Refractory Solid Tumors NCT00985868 | Cancer Research UK | Phase 1 |
| Terminated | Cyproheptadine Hydrochloride and Nutritional Supplementation in Treating Young Patients With Weight Loss With NCT00949117 | University of South Florida | Phase 2 |
| Completed | Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Cent NCT00994500 | National Cancer Institute (NCI) | Phase 1 |
| Terminated | Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating NCT00933985 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Tr NCT00929903 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Cixutumumab and Temsirolimus in Treating Younger Patients With Solid Tumors That Have Recurred or Not Responde NCT00880282 | National Cancer Institute (NCI) | Phase 1 |
| Terminated | Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Mali NCT00788125 | City of Hope Medical Center | Phase 1 / Phase 2 |
| Completed | Decision Making About Participating in Pharmacokinetic Studies in Patients Enrolled in a Phase I Treatment Cli NCT00890435 | Children's Oncology Group | — |
| Completed | Education Intervention in Encouraging Health Providers to Talk With Cancer Patients About the Use of Complemen NCT00608933 | M.D. Anderson Cancer Center | Phase 3 |
| Completed | Aflibercept in Treating Young Patients With Relapsed or Refractory Solid Tumors NCT00622414 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Evaluating Dactinomycin and Vincristine in Young Patients With Cancer NCT00674193 | Children's Oncology Group | — |
| Completed | IMC-A12 in Treating Young Patients With Relapsed or Refractory Ewing Sarcoma/Peripheral Primitive Neuroectoder NCT00609141 | National Cancer Institute (NCI) | Phase 1 |
| Unknown | Effect of Bevacizumab and VEGF on Platelet Clustering in Patients Who Are Receiving Bevacizumab for Cancer NCT00898794 | Kantonsspital Graubuenden | — |
| Terminated | Diphenhydramine, Lorazepam, and Dexamethasone in Treating Nausea and Vomiting Caused By Chemotherapy NCT00429702 | University of South Florida | Phase 2 |
| Unknown | CYP3A5 Gene as a Risk Factor for Kidney Damage in Young Patients With Cancer Treated With Ifosfamide NCT00514345 | Children's Cancer and Leukaemia Group | — |
| Terminated | Cancer Occurrence and Outcome in Young Patients Undergoing Cancer Treatment at the Vanderbilt-Ingram Cancer Ce NCT00670605 | Vanderbilt University | — |
| Completed | Bevacizumab and Cediranib Maleate in Treating Patients With Metastatic or Unresectable Solid Tumor, Lymphoma, NCT00458731 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Assessing Ear Damage in Young Cancer Patients Treated With Cisplatin NCT00458887 | Children's Oncology Group | — |
| Completed | High-Dose Methotrexate in Treating Young Patients With Solid Tumors NCT00513981 | Children's Cancer and Leukaemia Group | Phase 1 |
| Completed | Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagn NCT00638898 | City of Hope Medical Center | Phase 1 |
| Withdrawn | Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Re NCT00458744 | Children's Oncology Group | Phase 1 |
| Unknown | Evaluating the Side Effects and How Well Anticancer Drugs Work in Very Young Patients With Cancer NCT00897871 | Children's Cancer and Leukaemia Group | — |
| Completed | Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancer NCT00112996 | M.D. Anderson Cancer Center | Phase 3 |
| Completed | Pharmacokinetics of Daunorubicin in Young Patients With Cancer NCT00673257 | Children's Oncology Group | N/A |
| Withdrawn | Recombinant Human Mannose-Binding Lectin (MBL) in Treating Young Patients With MBL Deficiency and Fever and Ne NCT00886496 | Enzon Pharmaceuticals, Inc. | Phase 1 |
| Completed | Telephone-Based Cancer Education With or Without Telephone-Based Counseling in Young Participants NCT00459238 | Georgetown University | N/A |
| Completed | Sunitinib in Treating Young Patients With Refractory Solid Tumors NCT00387920 | National Cancer Institute (NCI) | Phase 1 |
| Completed | High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in T NCT00536601 | Roswell Park Cancer Institute | N/A |
| Completed | Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma NCT00363272 | National Cancer Institute (NCI) | Phase 1 |
| Unknown | Pharmacokinetics of Dactinomycin in Young Patients With Cancer NCT00900354 | Children's Cancer and Leukaemia Group | — |
| Withdrawn | Molecular Markers and Genetic Markers in Patients Undergoing Radiation Therapy for Cancer NCT00899808 | Rutgers, The State University of New Jersey | — |
| Completed | Dasatinib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Philadelphia Chromosome-Posi NCT00316953 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Br NCT00303940 | National Institutes of Health Clinical Center (CC) | Phase 1 |
| Completed | Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors NCT00138216 | Children's Oncology Group | Phase 1 |
| Completed | Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors NCT00281944 | National Cancer Institute (NCI) | Phase 1 |
| Completed | PEG-Interferon Alfa-2b in Treating Young Patients With Plexiform Neurofibroma NCT00253474 | National Institutes of Health Clinical Center (CC) | Phase 1 |
| Completed | Cyclophosphamide in Treating Young Patients With Severe Autoimmune Enteropathy NCT00258180 | Johns Hopkins University | Phase 2 |
| Completed | Tissue Sample Collection From Patients With Fanconi Anemia NCT00899522 | OHSU Knight Cancer Institute | — |
| Completed | Vorinostat With or Without Isotretinoin in Treating Young Patients With Recurrent or Refractory Solid Tumors, NCT00217412 | National Cancer Institute (NCI) | Phase 1 |
| Terminated | Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors NCT00112619 | Pediatric Brain Tumor Consortium | Phase 1 |
| Unknown | Polyvinylpyrrolidone-Sodium Hyaluronate Gel in Reducing Pain From Oral Mucositis in Young Patients With Cancer NCT00349024 | Children's Cancer and Leukaemia Group | N/A |
| Withdrawn | Daptomycin or Vancomycin in Treating Bacteria in the Blood in Patients With Neutropenia Caused By Chemotherapy NCT00296049 | Wake Forest University Health Sciences | N/A |
| Completed | Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors NCT00107458 | Children's Oncology Group | Phase 1 |
| Completed | Acupressure in Preventing Nausea and Vomiting in Young Cancer Patients Receiving Chemotherapy NCT00310063 | Wake Forest University Health Sciences | N/A |
| Completed | Donor Stem Cell Transplant in Treating Young Patients With Relapsed or Refractory Solid Tumors NCT00112645 | Milton S. Hershey Medical Center | Phase 1 |
| Completed | Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas NCT00101270 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Lenalidomide in Treating Young Patients With Relapsed or Refractory Solid Tumors or Myelodysplastic Syndromes NCT00104962 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancer NCT00357500 | Dana-Farber Cancer Institute | Phase 2 |
| Terminated | Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or Refractory Solid Tumors or NCT00101205 | National Cancer Institute (NCI) | Phase 1 |
| Unknown | Busulfan, Melphalan, and Antithymocyte Globulin Followed By Umbilical Cord Blood Transplant in Treating Young NCT00436761 | Milton S. Hershey Medical Center | Phase 1 |
| Recruiting | Collection and Storage of Tissue Samples From Patients Undergoing Surgery For Suspected Solid Tumors NCT00900471 | Wake Forest University Health Sciences | — |
| Completed | 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Young Patients With Relapsed or Refractory Solid Tumors o NCT00079404 | National Cancer Institute (NCI) | Phase 1 |
| Withdrawn | Collecting and Storing Blood Samples From Patients With Cancer NCT00900120 | University of Medicine and Dentistry of New Jersey | — |
| Withdrawn | Ovarian Damage in Young Premenopausal Women Undergoing Chemotherapy for Cancer NCT00402935 | Case Comprehensive Cancer Center | — |
| Completed | Decitabine, Doxorubicin, and Cyclophosphamide in Treating Children With Relapsed or Refractory Solid Tumors or NCT00075634 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Bevacizumab in Treating Young Patients With Refractory Solid Tumors NCT00085111 | National Cancer Institute (NCI) | Phase 1 |
| Terminated | Dextromethorphan in Treating Patients With Fatigue Caused by Cancer NCT00176540 | University of Medicine and Dentistry of New Jersey | N/A |
| Completed | Pemetrexed Disodium in Treating Young Patients With Recurrent Solid Tumors NCT00070473 | Children's Oncology Group | Phase 1 |
| Unknown | Umbilical Cord Blood for Stem Cell Transplantation in Treating Young Patients With Malignant or Nonmalignant D NCT00084695 | Milton S. Hershey Medical Center | Phase 2 |
| Terminated | Adderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and Depression NCT00069927 | University of South Florida | Phase 2 |
| Completed | Anidulafungin in Treating Immunocompromised Children With Neutropenia NCT00068471 | National Cancer Institute (NCI) | Phase 1 / Phase 2 |
| Completed | Cyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer Tr NCT00066248 | University of South Florida | Phase 2 |
| Completed | Study of @neWorld: A Virtual Community for Children With Cancer NCT00070421 | Leap of Faith Technologies | Phase 1 / Phase 2 |
| Completed | Irinotecan and Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases From Solid Tumors NCT00389584 | University of California, Davis | Phase 1 / Phase 2 |
| Completed | Oblimersen Plus Combination Chemotherapy and Dexrazoxane in Treating Children and Adolescents With Relapsed or NCT00039481 | National Cancer Institute (NCI) | Phase 1 |
| Completed | FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia NCT00053963 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Gefitinib in Treating Children With Refractory Solid Tumors NCT00040781 | National Cancer Institute (NCI) | Phase 1 |
| Completed | ABT-751 in Treating Young Patients With Refractory Solid Tumors NCT00036959 | National Institutes of Health Clinical Center (CC) | Phase 1 |
| Completed | Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors NCT00049023 | O'Dorisio, M S | Phase 1 |
| Completed | Bortezomib in Treating Children With Advanced Solid Tumors NCT00021216 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy NCT00030108 | National Institutes of Health Clinical Center (CC) | Phase 1 |
| Completed | Biological Therapy in Treating Children With Refractory or Recurrent Neuroblastoma or Other Tumors NCT00003750 | Children's Oncology Group | Phase 1 |
| Completed | Combination Chemotherapy, Peripheral Stem Cell Transplantation, and Biological Therapy in Treating Patients Wi NCT00027937 | Fred Hutchinson Cancer Center | Phase 2 |
| Completed | Carboplatin and Irinotecan in Treating Children With Refractory Solid Tumors NCT00024284 | Bristol-Myers Squibb | Phase 1 |
| Completed | Registration and Informed Consent Study for the Childhood Cancer Research Network NCT00433394 | Children's Oncology Group | N/A |
| Completed | Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas NCT00012181 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Tre NCT00006348 | Alliance for Clinical Trials in Oncology | Phase 3 |
| Completed | Ecteinascidin 743 in Treating Children With Refractory Solid Tumors NCT00006463 | Children's Oncology Group | Phase 1 |
| Completed | Irinotecan in Treating Children With Refractory or Advanced Solid Tumors Who Are Receiving Anticonvulsants NCT00008424 | Children's Oncology Group | Phase 1 |
| Completed | Enalapril in Treating Heart Damage Patients Who Received Anthracycline Chemotherapy for Childhood Cancer NCT00003070 | Children's Oncology Group | Phase 3 |
| Completed | Combination Chemotherapy in Treating Children With Solid Tumors That Have Not Responded to Previous Therapy NCT00006095 | Children's Oncology Group | Phase 1 |
| Completed | Rebeccamycin Analogue in Treating Children With Solid Tumors or Non-Hodgkin's Lymphoma NCT00006102 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors NCT00020150 | National Cancer Institute (NCI) | Phase 1 |
| Completed | BMS-214662 in Treating Patients With Solid Tumors NCT00005973 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Quality of Life in Children Treated for Cancer NCT00005881 | Children's Oncology Group | — |
| Completed | Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatmen NCT00005811 | National Cancer Institute (NCI) | Phase 2 |
| Completed | Oxaliplatin in Treating Children With Advanced Solid Tumors NCT00005844 | St. Jude Children's Research Hospital | Phase 1 |
| Completed | Irinotecan and Cisplatin With or Without Amifostine in Treating Children With Solid Tumors That Have Not Respo NCT00004919 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Fludarabine and Total-Body Irradiation Followed By Donor Stem Cell Transplant and Cyclosporine and Mycophenola NCT00112593 | Fred Hutchinson Cancer Center | N/A |
| Completed | Irinotecan in Treating Children With Refractory Solid Tumors NCT00004078 | Children's Oncology Group | Phase 2 |
| Completed | DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas NCT00004212 | Daiichi Sankyo | Phase 1 |
| Completed | Thalidomide in Treating Patients With Chronic Graft-Versus-Host Disease Following Bone Marrow Transplant NCT00003894 | Roswell Park Cancer Institute | Phase 2 |
| Completed | Antibiotic Therapy With or Without G-CSF in Treating Children With Neutropenia and Fever Caused by Chemotherap NCT00003739 | Children's Oncology Group | Phase 3 |
| Completed | Glutamine in Treating Side Effects in Children Who Are Undergoing Stem Cell Transplantation NCT00003898 | Roswell Park Cancer Institute | Phase 2 |
| Completed | Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematolog NCT00003816 | Roswell Park Cancer Institute | Phase 2 / Phase 3 |
| Completed | Irinotecan Followed By Fluorouracil and Leucovorin in Treating Patients With Stage III or Stage IV Colorectal NCT00004005 | St. Jude Children's Research Hospital | Phase 2 |
| Completed | Thalidomide and Cyclophosphamide in Treating Children With Recurrent or Refractory Childhood Cancers NCT00003754 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Completed | Irinotecan in Treating Children With Refractory or Progressive Solid Tumors NCT00016861 | Texas Children's Cancer Center | Phase 1 |
| Completed | Irofulven in Treating Children With Recurrent or Refractory Solid Tumors NCT00003370 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Tirapazamine Plus Cyclophosphamide in Treating Children With Refractory Solid Tumors NCT00003288 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Arsenic Trioxide in Treating Patients With Advanced Solid Tumors NCT00003630 | Memorial Sloan Kettering Cancer Center | Phase 1 |
| Completed | Fenretinide in Treating Children With Solid Tumors NCT00003191 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Prevention of Infection in Patients With Hematologic Cancer and Persistent Fever Caused by a Low White Blood C NCT00003805 | European Organisation for Research and Treatment of Cancer - EORTC | Phase 3 |
| Completed | High-Dose Thiotepa Plus Peripheral Stem Cell Transplantation in Treating Patients With Refractory Solid Tumors NCT00003173 | Memorial Sloan Kettering Cancer Center | Phase 2 |
| Terminated | Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Recurrent or Refra NCT00003194 | Seattle Children's Hospital | Phase 1 |
| Unknown | Chemotherapy in Treating Young Patients With Recurrent or Refractory Meningeal Leukemia, Lymphoma, or Solid Tu NCT00003073 | Pacira Pharmaceuticals, Inc | Phase 1 |
| Completed | Gemcitabine in Treating Children With Refractory Solid Tumors NCT00005577 | National Cancer Institute (NCI) | Phase 1 |
| Completed | Gallium Nitrate in Treating Children With Brain Tumor, Neuroblastoma, Rhabdomyosarcoma, Non-Hodgkin's Lymphoma NCT00002543 | Medical College of Wisconsin | Phase 1 |
| Completed | Interferon Alfa in Treating Children With HIV-Related Cancer NCT00002621 | Children's Oncology Group | Phase 2 |
| Completed | Carboxypeptidase-G2 in Treating Nervous System Toxic Effects in Patients Given an Overdose of Intrathecal Meth NCT00018967 | National Cancer Institute (NCI) | N/A |
| Completed | Development of Strategies to Increase Enrollment in Clinical Trials for Children With Cancer NCT00002485 | Children's Oncology Group | — |
| Completed | High-Dose Chemotherapy, Total-Body Irradiation, and Autologous Stem Cell Transplantation or Bone Marrow Transp NCT00060255 | Roswell Park Cancer Institute | Phase 2 |
| Withdrawn | Donor White Blood Cell Infusion in Treating Patients With Metastatic or Unresectable Cancer NCT00607802 | Wake Forest University Health Sciences | N/A |