Trials / Terminated
TerminatedNCT00176540
Dextromethorphan in Treating Patients With Fatigue Caused by Cancer
A Pilot Trial to Evaluate the Effects of Dextromethorphan in Patients Suffering From Cancer-Related Fatigue
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (estimated)
- Sponsor
- University of Medicine and Dentistry of New Jersey · Academic / Other
- Sex
- All
- Age
- 12 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
RATIONALE: Dextromethorphan may help relieve fatigue in patients with cancer. PURPOSE: This clinical trial is studying how well dextromethorphan works in treating patients with fatigue caused by cancer.
Detailed description
OBJECTIVES: Primary * Assess the effects of dextromethorphan hydrobromide in patients with cancer-related fatigue. Secondary * Correlate the changes in cancer-related fatigue with the levels of plasma homocysteine versus red blood cell folate. OUTLINE: This is a multicenter, open-label, pilot study. Patients receive oral dextromethorphan hydrobromide 3 times a day on days 1-7. Treatment repeats weekly for up to 3 weeks in the absence of disease progression or unacceptable toxicity. PROJECTED ACCRUAL: A total of 30 patients will be accrued for this study.
Conditions
- Fatigue
- Unspecified Adult Solid Tumor, Protocol Specific
- Unspecified Childhood Solid Tumor, Protocol Specific
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | dextromethorphan hydrobromide |
Timeline
- Start date
- 2003-10-01
- Primary completion
- 2007-08-01
- Completion
- 2007-08-01
- First posted
- 2005-09-15
- Last updated
- 2011-05-17
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT00176540. Inclusion in this directory is not an endorsement.