| Recruiting | RRx-001 for Reducing Oral Mucositis in Patients Receiving Chemotherapy and Radiation for Head and Neck Cancer Oral Mucositis | Phase 2 | 2024-04-02 |
| Terminated | RRx-001 Given With Irinotecan and Temozolomide for Pediatric Patients With Recurrent or Progressive Malignant Brain Tumor, Recurrent, Brain Tumor, Pediatric, Central Nervous System Neoplasms | Phase 1 | 2023-01-26 |
| Active Not Recruiting | A Phase 3, Controlled, Open-label, Global Randomized Study of RRx-001 With a Platinum Doublet or a Platinum Do Carcinoma, Small Cell Lung | Phase 3 | 2022-08-01 |
| Recruiting | A Study of AdAPT-001 in Subjects With Sarcoma and Refractory Solid Tumors Solid Tumor, Adult, Cancer, Neoplasms | Phase 2 | 2021-03-29 |
| Terminated | RRx-001 Sequentially With a Platinum Doublet or a Platinum Doublet in Third-Line or Beyond in Patients With Sm Carcinoma, Small Cell Lung | Phase 3 | 2018-12-24 |
| Completed | Safety and Efficacy of RRx-001 in the Attenuation of Oral Mucositis in Patients Receiving Chemoradiation for t Oral Mucositis | Phase 2 | 2018-07-12 |
| Completed | RRx-001 + Radiation + Temozolomide In Newly Diagnosed Glioblastoma and Anaplastic Gliomas Glioblastoma, Oligodendroglioma, Anaplastic Oligodendroglioma | Phase 1 | 2017-02-14 |
| Terminated | RRx-001 in Combination With Irinotecan in Metastatic or Advanced Cancer (PAYLOAD) Malignant Solid Tumor, Metastatic Cancer, Advanced Cancer | Phase 1 | 2016-08-30 |
| Completed | A Phase I, Open-Label, Multiple Ascending Dose Study of RRx-001 and Nivolumab Malignant Solid Tumor, Lymphoma | Phase 1 | 2015-07-21 |
| Terminated | RRx-001 in Second Line Treatment of Advanced Cholangiocarcinoma Prior to Readministration of First-Line Therap Cholangiocarcinoma | Phase 2 | 2015-07-16 |
| Completed | RRx-001 in Lung Cancer, Ovarian Cancer and Neuroendocrine Tumors Prior to Re-administration of Platinum Based Small Cell Carcinoma, Carcinoma, Non-Small-Cell Lung, Neuroendocrine Tumors | Phase 2 | 2015-06-01 |
| Completed | Dose-Escalation Study of RRx-001 in Combination With Whole Brain Radiation in Subjects With Brain Metastases Brain Metastases | Phase 1 | 2015-02-06 |
| Completed | A Phase 2 Randomized, Open-Label Study of RRx-001 vs Regorafenib in Subjects With Metastatic Colorectal Cancer Colorectal Neoplasms | Phase 2 | 2014-05-01 |
| Terminated | A Phase 1 Pilot Study of the Subcutaneous (s.c.) Route to Facilitate the Administration of RRx-001 Malignant Solid Tumor, Lymphomas | Phase 1 | 2014-04-01 |
| Completed | Safety and Pharmacokinetic Study of RRx-001 in Cancer Subjects Malignant Solid Tumor, Lymphomas | Phase 1 | 2011-09-01 |
| No Longer Available | Expanded Access for PSV Personalized Oncolytic Viruses Cancer | — | — |