| Terminated | A Study to Evaluate an Intra-Articular Injection of ZILRETTA Versus Triamcinolone Acetonide, Immediate Release Osteoarthritis of Hip | Phase 2 | 2025-07-25 |
| Active Not Recruiting | A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee Osteoarthritis (OA) of the Knee | Phase 2 | 2025-02-26 |
| Recruiting | Study to Assess the Efficacy and Safety of Iovera®° System in Subjects With Upper Extremity Spasticity Spasticity, Cerebral or Spinal Condition | N/A | 2024-07-11 |
| Recruiting | Study to Evaluate the Pharmacokinetics and Safety of EXPAREL for Postoperative Analgesia in Subjects Undergoin Postoperative Pain | Phase 1 | 2024-03-29 |
| Recruiting | ZILRETTA in Subjects With Shoulder Osteoarthritis Glenohumeral Osteoarthritis | Phase 3 | 2024-02-05 |
| Completed | Phase 1, Dose Escalation Study to Evaluate of Safety, Pharmacokinetics and Pharmacodynamics of Liposomal Bupiv Healthy | Phase 1 | 2023-04-18 |
| Completed | Phase 3, Sciatic Nerve Block With EXPAREL for Subjects Undergoing Bunionectomy Bunionectomy, Hallux Valgus | Phase 3 | 2022-02-15 |
| Completed | Phase 3 Adductor Canal Block With EXPAREL in Subjects Undergoing Primary Unilateral Total Knee Arthroplasty Knee Osteoarthritis, Pain Management | Phase 3 | 2022-01-18 |
| Recruiting | Innovations in Genicular Outcomes Registry Knee Osteoarthritis | — | 2021-09-23 |
| Completed | Study to Evaluate the Safety and Tolerability of FX301 in Patients Undergoing Bunionectomy Pain, Postoperative, Bunion | Phase 1 | 2021-03-15 |
| Completed | Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of EXPAREL, EXPAREL Admixed With Bupivacaine HCl Lower Extremity Surgery, Bunion, Metatarsophalangeal Fushion | Phase 3 | 2020-10-20 |
| Terminated | Study to Evaluate Iovera®° in Adult Patients Undergoing Total Knee Arthroplasty Post-Operative Pain Management | N/A | 2020-09-30 |
| Withdrawn | Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Evaluate the Efficacy, Safety, an Bunion, Metatarsophalangeal Fusion, Midfoot Fusion | Phase 3 | 2020-06-15 |
| Terminated | Evaluation of Safety, Pharmacokinetics and Pharmacodynamics of EXPAREL® Administered Via a Single Intrathecal Healthy | Phase 1 | 2020-06-08 |
| Active Not Recruiting | Study to Evaluate the Safety and Tolerability of FX201 in Patients with Osteoarthritis of the Knee Osteoarthritis, Knee | Phase 1 | 2020-03-02 |
| Completed | Study to Evaluate the Pharmacokinetics and Safety of EXPAREL Administered as a Pectoral Plane Block in Women U Breast Augmentation | Phase 1 | 2019-12-19 |
| Terminated | Study to Evaluate the Efficacy and Safety of FX006 in Patients With Glenohumeral Osteoarthritis or Shoulder Ad Osteoarthritis of the Shoulder, Adhesive Capsulitis | Phase 2 | 2019-11-07 |
| Withdrawn | EXPAREL Facia Iliaca Compartment Block for Intertrochanteric Hip Fracture Hip Fractures, Intertrochanteric Fractures | Phase 4 | 2019-08-26 |
| Terminated | Phase 4 Study in Adult Subjects Undergoing Posterior Lumbar Spine Surgeries Postoperative Pain Management | Phase 4 | 2019-07-31 |
| Completed | Study to Evaluate a Procedure for Intra-articular Injection of FX006 in Patients With Osteoarthritis of the Hi Osteoarthritis, Hip | Phase 2 | 2019-07-30 |
| Completed | Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety, of EXPAREL Administered as Sciatic Nerve Bunion | Phase 1 | 2019-07-26 |
| Withdrawn | Evaluate the Iovera° Device in Treating Pain Associated With Anterior Cruciate Ligament Reconstruction ACL Reconstruction | N/A | 2019-05-01 |
| Completed | Multicenter Study for Pediatric Subjects Evaluating Pharmacokinetics and Safety of EXPAREL Postoperative Pain Management | Phase 3 | 2019-04-02 |
| Completed | Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean Section Elective Cesarean Section, Pain Management | Phase 4 | 2019-03-04 |
| Terminated | Study to Evaluate the Efficacy and Safety of FX006 in Patients With Hip Osteoarthritis Osteoarthritis, Hip | Phase 3 | 2018-12-12 |
| Withdrawn | Iovera° to Treat Pain Associated With ACL Reconstruction and Rehabilitation Anterior Cruciate Ligament Reconstruction | N/A | 2018-10-01 |
| Terminated | Study in Adult Subjects Undergoing Posterolateral Thoracotomy Postoperative Pain Management | Phase 1 | 2018-05-03 |
| Completed | Study to Evaluate the Effect of FX006 on Synovial Inflammation in Patients With OA of the Knee Osteoarthritis, Knee | Phase 3 | 2018-04-24 |
| Completed | Study in Pediatric Subjects Evaluating Pharmacokinetics and Safety of EXPAREL Postoperative Pain Management | Phase 1 | 2018-04-10 |
| Completed | Study to Compare Exposure of TA Following Administration of FX006 or TAcs in Patients With OA of the Shoulder Osteoarthritis of the Shoulder, Osteoarthritis of the Hip | Phase 2 | 2017-12-18 |
| Completed | Study to Compare Exposure of TA Following Administration of Either FX006 or TAcs in Patients With Bilateral Kn Bilateral Knee Osteoarthritis | Phase 2 | 2017-12-06 |
| Completed | Treatment With Iovera° for Total Knee Arthroplasty (TKA) Post-Operative Pain Total Knee Arthroplasty | N/A | 2017-11-06 |
| Completed | Evaluate the Safety and Efficacy of EXPAREL When Administered Via Infiltration Into the TAP vs. Bupivacaine Al C-Section, Pain Management | Phase 4 | 2017-06-01 |
| Terminated | Phase 4, Controlled Study in Adult Subjects Undergoing Primary, 1-2 Level, Open Lumbar Spinal Fusion Surgery Postoperative Pain Management | Phase 4 | 2017-02-21 |
| Completed | Study to Assess the Safety of Repeat Administration of FX006 Administered to Patients With Osteoarthritis of t Osteoarthritis of the Knee | Phase 3 | 2017-02-20 |
| Completed | PK Study of EXPAREL in Subjects Undergoing Open Spinal Fusion or Reconstructive Surgery Spinal Fusion, Pain Management | Phase 1 | 2016-12-01 |
| Terminated | Study of Local Administration of DepoTXA for Reduced Postsurgical Bleeding in Subjects Undergoing TKA Total Knee Arthroplasty | Phase 2 | 2016-10-28 |
| Completed | Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block With EXPAREL in Total Knee Arthroplasty Pain | Phase 3 | 2016-06-03 |
| Completed | Efficacy, Safety, and Pharmacokinetics of Brachial Plexus Block With EXPAREL in Shoulder Surgery Pain | Phase 3 | 2016-05-09 |
| Completed | Local Infiltration Analgesia With and Without EXPAREL Following Total Knee Arthroplasty Pain | Phase 4 | 2016-04-18 |
| Completed | Study to Assess the Effects of FX006 on Blood Glucose in Patients With OA of the Knee and Type 2 Diabetes Osteoarthritis of the Knee, Type 2 Diabetes Mellitus | Phase 2 | 2016-04-01 |
| Completed | Study to Characterize the PK and Local Extent and Duration of Exposure From FX006 in Patients With OA of the K Osteoarthritis of the Knee | Phase 2 | 2015-11-01 |
| Completed | Evaluation of EXPAREL for Prolonged Postsurgical Analgesia in Subjects Undergoing Third Molar Extraction Dental Pain | Phase 3 | 2015-08-01 |
| Terminated | Evaluation of the Safety and Efficacy of EXPAREL When Administered Into the TAP in Subjects Undergoing Cesarea Pain | Phase 4 | 2015-05-01 |
| Terminated | Proof of Concept Study Comparing FX006 to Kenalog®-40 in Patients With Post-Traumatic Osteoarthritis of the Kn Post-traumatic Osteoarthritis of the Knee | Phase 2 | 2015-02-01 |
| Completed | Study of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the Knee Osteoarthritis of the Knee | Phase 3 | 2015-01-01 |
| Completed | A Randomized, Study to Evaluate the Iovera° Device in Treating Pain Associated With Total Knee Arthroplasty Arthritis of the Knee | N/A | 2014-12-01 |
| Completed | Pharmacokinetics and Safety of Bupivacaine HCl Spinal Block and EXPAREL Local Infiltration in Total Knee Arthr Pain | Phase 4 | 2014-12-01 |
| Completed | Study to Evaluate the Iovera° Device for Temporary Relief From Knee Pain Knee Osteoarthritis | N/A | 2014-10-20 |
| Completed | EXPAREL Infiltration in Subjects Undergoing Femoral Nerve Block With Bupivacaine HCl for Total Knee Arthroplas Pain | Phase 4 | 2014-09-01 |
| Completed | Pharmacokinetic Evaluation of EXPAREL in Adults Undergoing Tonsillectomy Pain | Phase 4 | 2014-08-01 |
| Completed | Safety and Pharmacokinetics Study of Redosing EXPAREL in Healthy Volunteers Healthy Volunteers | Phase 1 | 2014-08-01 |
| Completed | Study of FX006 vs Normal Saline in Patients With Osteoarthritis of the Knee Osteoarthritis of the Knee | Phase 2 | 2014-04-01 |
| Completed | Study to Characterize the Local Duration of Exposure From FX006 in Patients With Osteoarthritis of the Knee Osteoarthritis of the Knee | Phase 2 | 2013-11-01 |
| Completed | Prospective Study Evaluating the Treatment of Hyperdynamic Forehead Wrinkles Wrinkles | — | 2013-09-01 |
| Completed | Effectiveness and Safety Study of the Iovera Device for the Temporary Reduction in the Appearance of Forehead Forehead Wrinkles | N/A | 2013-09-01 |
| Terminated | EXPAREL Administered by Infiltration Into the TAP for Prolonged Postsurgical Analgesia in Lower Abdominal Surg Pain | Phase 4 | 2013-08-01 |
| Completed | Study Evaluating Treatment of Upper Limb Spasticity Using the Cryo-Touch III Device Upper Limb Spasticity | N/A | 2013-04-01 |
| Completed | A Prospective Study Evaluating the Treatment of Forehead and/or Glabellar Lines With the Cryo-Touch IV Device Frown Lines, Glabellar Frown Lines | — | 2013-01-01 |
| Completed | Intercostal Nerve Block With Liposome Bupivacaine in Subjects Undergoing Posterolateral Thoracotomy Posterolateral Thoracotomy, Postoperative Pain | Phase 3 | 2012-12-01 |
| Completed | Study Evaluating Treatment of Forefoot Pain Related to Nerve Entrapment Using the Cryo-Touch III Device Entrapment Neuropathy | N/A | 2012-11-01 |
| Completed | Study Evaluating the Treatment of Forehead and/or Glabellar Lines With the CRYO-TOUCH III Device Frown Lines, Glabellar Frown Lines | — | 2012-11-01 |
| Completed | Pain Control in Bariatric Patients: EXPAREL(R) vs. the On-Q(R) Pain Ball Obesity | Phase 4 | 2012-11-01 |
| Completed | Study Evaluating the Treatment of Occipital Neuralgia Occipital Neuralgia | N/A | 2012-10-01 |
| Completed | A Prospective Study Evaluating the Treatment of Knee Osteoarthritis With the Cryo-Touch III Device Osteoarthritis of the Knee | N/A | 2012-09-01 |
| Completed | Femoral Nerve Block With Liposome Bupivacaine for Postsurgical Analgesia Following Total Knee Arthroplasty Postoperative Pain | Phase 2 / Phase 3 | 2012-09-01 |
| Terminated | EXPAREL Administered Into the TAP for Analgesia in Subjects Undergoing Open Total Abdominal Hysterectomy Postoperative Pain | Phase 4 | 2012-08-01 |
| Completed | Pharmacokinetic and Pharmacodynamic Study of FX006 in Patients With Osteoarthritis of the Knee Osteoarthritis of the Knee | Phase 2 | 2012-07-01 |
| Completed | Probe Configuration and Time-Temperature Dose Ranging for Understanding of Skin Lesion Effects Histological Response of Tissue to Cold | N/A | 2012-06-01 |
| Completed | Study of FX006 in Patients With Osteoarthritis of the Knee Osteoarthritis of the Knee | Phase 2 | 2012-06-01 |
| Terminated | A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B302 Bowel Obstruction | Phase 4 | 2012-05-01 |
| Completed | Study of EXPAREL in Patients Undergoing Breast Augmentation Mammoplasty, Postoperative Pain | Phase 4 | 2012-04-01 |
| Completed | EXPAREL Infiltrated Into the TAP for Postoperative Analgesia in Unilateral Abdominal Hernia Repair Hernia | Phase 4 | 2012-04-01 |
| Completed | A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B501 Retraction of Colostomy | Phase 4 | 2012-03-01 |
| Terminated | A Health Economic Trial in Adult Patients Undergoing Open Colectomy MA402S23B301 Bowel Obstruction | Phase 4 | 2012-03-01 |
| Completed | TAP-patients With Robotic Assisted Lap Prostatectomy Postsurgical Pain, Analgesia, Prostatectomy | Phase 4 | 2012-03-01 |
| Completed | A Health Economic Trial in Adult Patients Undergoing Ileostomy Reversal MA402S23B504 Retraction of Colostomy | Phase 4 | 2012-01-01 |
| Completed | Adult Patients Undergoing Open Colectomy MA402S23B303 Bowel Obstruction | Phase 4 | 2011-12-01 |
| Terminated | A Health Economic Trial in Adult Patients Undergoing Laparoscopic Colectomy Bowel Obstruction | Phase 4 | 2011-12-01 |
| Completed | A Study to Evaluate the Safety and Effectiveness of the Cryo-Touch II Device for the Treatment of Forehead and Facial Wrinkles, Skin Aging | Phase 2 / Phase 3 | 2011-09-01 |
| Completed | Cryo-Touch III Refinement Study Investigational Plan Facial Wrinkles, Skin Aging | Phase 2 / Phase 3 | 2011-06-01 |
| Completed | Study of FX005 for the Treatment of Pain in Patients With Osteoarthritis of the Knee Osteoarthritis, Knee | Phase 1 / Phase 2 | 2010-12-01 |
| Completed | Cryo-Touch II for the Treatment of Wrinkles Facial Wrinkles | Phase 2 / Phase 3 | 2010-07-01 |
| Completed | Observational Study to Assess Long-Term Follow-Up of Breast Augmentation Subjects Postoperative Pain | — | 2010-02-01 |
| Completed | Study of Pain Control in Hemorrhoidectomy Hemorrhoid | Phase 3 | 2009-05-01 |
| Completed | Study of Postoperative Analgesia in Bunionectomy Bunion, Hallux Valgus | Phase 3 | 2009-04-01 |
| Completed | Study of the MyoScience Tissue Remodeling Device for Facial Rejuvenation Facial Rhytides | Phase 1 / Phase 2 | 2009-02-01 |
| Completed | Hepatic Impairment Study: Pharmacokinetics in Healthy and Hepatically Impaired Subjects Pain, Hepatic Impairment | Phase 1 | 2009-01-01 |
| Terminated | Dose Finding Posterolateral Thoracotomy Study Postoperative Pain | Phase 2 | 2008-12-01 |
| Terminated | Phase 3 Study of Local Administration of SKY0402 for Postoperative Analgesia in Subject Undergoing Breast Augm Pain | Phase 3 | 2008-11-01 |
| Completed | Evaluate the Onset of Action of SKY0402 Following Local Infiltration in Healthy Volunteers Postoperative Pain Management | Phase 1 | 2008-10-01 |
| Completed | A Phase 3 Study to Evaluate the Safety and Efficacy of SKY0402 in Subjects Undergoing Total Knee Arthroplasty Postoperative Pain | Phase 3 | 2008-08-01 |
| Completed | Study to Evaluate Postoperative Analgesia in Subjects Undergoing Hemorrhoidectomy Hemorrhoids | Phase 3 | 2008-08-01 |
| Completed | Evaluation of the Safety and Efficacy of a Single Dose of SKY0402 in Subjects Undergoing Augmentation Mammopla Postoperative Pain | Phase 2 | 2008-03-01 |
| Completed | Phase 2 Dose-Ranging Study of SKY0402 for Prolonged Postoperative Analgesia in Subject Undergoing Hemorrhoidec Postoperative Pain | Phase 2 | 2007-09-01 |
| Completed | Dose-Ranging Study for Prolonged Postoperative Analgesia in Subject Undergoing Total Knee Arthroplasty Postoperative Pain | Phase 2 | 2007-06-01 |
| Completed | Phase 1 Thorough QT Study in Young Healthy Volunteers Postoperative Pain | Phase 1 | 2007-06-01 |
| Completed | Dose-ranging Study for Postoperative Analgesia in Subjects Undergoing Primary Unilateral Inguinal Hernia Repai Postoperative Pain | Phase 2 | 2007-06-01 |
| Completed | Safety, Efficacy, and Pharmacokinetics of SKY0402 Administered as a Nerve Block in Subjects Undergoing Bunione Postoperative Pain | Phase 2 | 2005-03-01 |
| Completed | Evaluation of the Safety, Efficacy, and Pharmacokinetics of SKY0402 in Subjects Undergoing Inguinal Hernia Rep Inguinal Hernia | Phase 2 | 2004-12-01 |
| Completed | DepoCyt Therapy in Patients With Neoplastic Meningitis From Lymphoma or a Solid Tumor Meningeal Neoplasms | Phase 4 | 2001-04-01 |
| Unknown | Chemotherapy in Treating Young Patients With Recurrent or Refractory Meningeal Leukemia, Lymphoma, or Solid Tu Brain and Central Nervous System Tumors, Leukemia, Lymphoma | Phase 1 | 1997-02-01 |