Trials / Conditions / Tobacco Dependence

Tobacco Dependence

149 registered clinical trials studyying Tobacco Dependence — 18 currently recruiting.

Status	Trial	Sponsor	Phase
Not Yet Recruiting	Chatbot for Online Support Groups to Treat Tobacco Addiction NCT06952725	University of California, Irvine	N/A
Not Yet Recruiting	Varenicline for Smoking Reduction in Veterans Not Ready To Quit NCT06966362	VA Office of Research and Development	Phase 4
Recruiting	C-Raven, a Virtual Tobacco Cessation Intervention in Residency Clinics NCT07220356	Johns Hopkins University	Phase 4
Recruiting	Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness NCT07148232	University of California, San Francisco	Phase 4
Enrolling By Invitation	Cytisine vs Nicotine Replacement Therapy NCT03249428	Ottawa Hospital Research Institute	N/A
Not Yet Recruiting	Semaglutide for Smoking Cessation in Patients With Diabetes NCT07059377	Ottawa Heart Institute Research Corporation	Phase 3
Not Yet Recruiting	Smoking Cessation Intervention Including Health Navigators to Address Unmet Social Needs of Parents Who Smoke NCT06651684	St. Justine's Hospital	N/A
Recruiting	Reach Through Equitable Implementation in Utah NCT06881069	University of Utah	N/A
Enrolling By Invitation	Effect of Nicotine Gingival Fibroblast Intoxication on the Response of Periodontal Treatment NCT07491627	University of Liege	N/A
Recruiting	Effect of Yoga on Reducing Craving in Tobacco Dependent Individuals NCT06488443	University of Pittsburgh	N/A
Recruiting	Cannabidiol for Reducing Cigarette Use NCT06218056	University of California, Los Angeles	Phase 2
Completed	C-Raven, a Virtual Tobacco Cessation Intervention in the Community NCT06545669	Johns Hopkins University	Phase 4
Completed	Positive Psychology for Smoking Cessation NCT06632756	Dartmouth-Hitchcock Medical Center	N/A
Recruiting	Harm Reduction for Smokers With Mental Illness NCT06543407	Dartmouth-Hitchcock Medical Center	N/A
Recruiting	Use of Nicotine Pouches Among Daily Smokers NCT06043362	Milton S. Hershey Medical Center	N/A
Recruiting	Smoke-free Home Study in Subsidized Housing NCT06170437	University of California, San Francisco	N/A
Completed	Cooling Agent Pilot Among Adult Menthol Smokers NCT06477601	University of Kansas Medical Center	N/A
Completed	Testing C-Raven, a Virtual Tobacco Cessation Intervention, in the Community NCT06289192	Johns Hopkins University	Phase 4
Completed	Tobacco Cessation Care for Cancer Patients by Automated Interactive Outreach NCT05829824	University of California, San Francisco	N/A
Withdrawn	Equitable Smoking Relapse Prevention NCT05625685	Bryan W. Heckman	N/A
Recruiting	Adapting and Evaluating a Tobacco Use Cessation Program for People Living With HIV in Uganda and Zambia NCT05487807	University of Southern California	Phase 1
Recruiting	FRESH Delivers: An Innovative Approach to Reducing Tobacco Use Among Rural Smokers NCT05429892	University of Arkansas	N/A
Completed	Testing the Effect of ENDS Flavors on Neurotransmission NCT05836051	Milton S. Hershey Medical Center	N/A
Completed	DBT for Smoking Cessation in High Risk Veterans NCT06687577	Veterans Medical Research Foundation	N/A
Active Not Recruiting	Assessment of Biomarkers in Children to Help Parents Quit Tobacco NCT04832659	Massachusetts General Hospital	N/A
Completed	Interactive Mobile Doctor (iMD) to Promote Tobacco Cessation Among Cancer Patients NCT05021185	University of California, San Francisco	N/A
Recruiting	Oral Cannabidiol for Tobacco Cessation NCT05445804	Johns Hopkins University	Phase 1
Completed	Does Switching to Nicotine Containing Electronic Cigarettes Reduce Health Risk Markers NCT03625986	Milton S. Hershey Medical Center	N/A
Completed	CO Monitoring for Tobacco Cessation in Quitlines NCT05327660	Consumer Wellness Solutions	Phase 1 / Phase 2
Completed	Mixed Presentation on Social Media NCT05066126	University of Pennsylvania	N/A
Completed	Cigarette Smoking in Smokers With and Without Schizophrenia NCT04001114	University of Maryland, Baltimore	N/A
Completed	UW Withdraw From Tobacco Study NCT04969198	University of Wisconsin, Madison	Phase 2
Completed	Low Nicotine Cigarettes Plus Electronic Cigarettes NCT04058717	Milton S. Hershey Medical Center	N/A
Completed	Measuring Neuroadaptations in Response to Very Low Nicotine Content Cigarettes NCT03612960	Milton S. Hershey Medical Center	N/A
Completed	Identifying Effective Treatment for Veterans Unwilling to Quit Smoking NCT04061720	VA Office of Research and Development	N/A
Completed	Establishing the Effect of Flavor on the Addictive Potential of Electronic Cigarettes NCT03905928	Milton S. Hershey Medical Center	N/A
Completed	Assisting Smokers to Switch to a JUUL E-Cigarette by Devaluing Combustible Cigarettes NCT04188197	Rose Research Center, LLC	N/A
Recruiting	Early Withdrawal Exposure and Negative Affect Withdrawal (NAW) Regulation Training for Smoking Cessation NCT03912194	University of Alabama at Birmingham	Phase 3
Completed	Personalized Feedback for Distress Intolerant Smokers NCT03918031	University of Houston	N/A
Completed	An Extended Facebook Intervention for Young Sexual and Gender Minority Smokers NCT03553992	University of California, San Francisco	N/A
Withdrawn	Clinical Trial of an Innovative Digital Therapeutic for Smoking Cessation With Biochemical Verification NCT05440721	Click Therapeutics, Inc.	N/A
Completed	Innovative Digital Therapeutic for Smoking Cessation NCT03694327	My Digital Study	N/A
Unknown	The Interplay Between Addiction to Tobacco Smoking and Sleep Quality Among Healthy Adults NCT04265339	The Max Stern Academic College Of Emek Yezreel	N/A
Completed	Using Non-invasive Brain Stimulation (tDCS) With Varenicline for Treating Tobacco Dependence NCT03841292	Centre for Addiction and Mental Health	N/A
Completed	Addictive Potential of LCCs in Dual Users NCT03496077	UConn Health	N/A
Completed	Varenicline OTC Trial on Efficacy and Safety NCT03557294	Arizona State University	Phase 4
Terminated	Targeted Pharmacological and Behavioral Treatments for Smoking in Schizophrenia Study 1 NCT03507127	Brown University	Phase 2
Completed	A Facebook Intervention for Young Sexual and Gender Minority Smokers NCT03259360	University of California, San Francisco	N/A
Terminated	Electroretinogram: a New Human Biomarker for Smoking Cessation Treatment NCT03213418	New York State Psychiatric Institute	N/A
Completed	UW Quitting Using Intensive Treatment Study (QUITS) NCT03176784	University of Wisconsin, Madison	Phase 4
Completed	Personalized Feedback for Smokers With Elevated Anxiety Sensitivity NCT03382093	University of Houston	N/A
Completed	Clinical Study to Assess Bioequivalence Between Nicorette Extra Mint Gum and Nicorette® Mint Gum in Healthy Sm NCT03259607	McNeil AB	Phase 1
Completed	Helping Poor Smokers Quit NCT03194958	Washington University School of Medicine	N/A
Completed	A Bioequivalence Study Between Two Nicotine Replacement Therapies in Adult Healthy Smokers Motivated to Quit. NCT03130179	McNeil AB	Phase 1
Completed	The Appeal and Impact of E-cigarettes in Smokers With SMI NCT03050853	Dartmouth-Hitchcock Medical Center	N/A
Withdrawn	Preventing Tobacco Relapse With Omega-3s Trial NCT03113370	Vanderbilt University Medical Center	N/A
Completed	Using a Teachable Moment Communication Process to Improve Outcomes of Quitline Referrals NCT02764385	Case Western Reserve University	N/A
Completed	European Regulatory Science on Tobacco: Policy Implementation to Reduce Lung Diseases (EUREST-PLUS) NCT02773836	European Network For Smoking and Tobacco Prevention	—
Completed	Clinical Trial of Smoking Cessation Mobile Phone Program NCT02656745	Click Therapeutics, Inc.	N/A
Completed	Smoking-cessation: A Spanish-Language Clinical Trial NCT02611076	H. Lee Moffitt Cancer Center and Research Institute	N/A
Completed	Tobacco Treatment for Employable Californians, Total IMPACT Study NCT02478697	Stanford University	N/A
Completed	Reduced Nicotine Content Cigarettes in Smokers of Lower Socioeconomic Status NCT01928719	Milton S. Hershey Medical Center	N/A
Completed	Cardiovascular Effects of Chronic Snus Use NCT02564289	Umeå University	—
Completed	Reduced Nicotine Cigarettes in Smokers With Mood and Anxiety Disorders NCT01928758	Milton S. Hershey Medical Center	N/A
Completed	Healing and Empowering Alaskan Lives Towards Healthy-Hearts Study NCT02137902	Stanford University	N/A
Completed	Changing Pediatric Office Systems Nationally to Address Parental Tobacco Use NCT01882348	Massachusetts General Hospital	N/A
Completed	Study to Determine the Efficacy and Safety of a Novel Nicotine Replacement Therapy NCT02355665	McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.	Phase 3
Completed	A Multi-center Trial of IMPaCT CHW Support for Chronically-ill Patients NCT02347787	University of Pennsylvania	N/A
Completed	Varenicline for Co-occurring Cannabis and Tobacco Use NCT04595318	Albert Einstein College of Medicine	Phase 4
Terminated	Tobacco Treatment as Augmentation for Cognitive Processing Therapy for PTSD NCT02012452	VA Office of Research and Development	N/A
Completed	Very Low Nicotine Cigarettes in Smokers With Schizophrenia NCT02019459	Brown University	Phase 2
Completed	Behavioral Activation for Smoking Cessation in PTSD NCT01995123	VA Office of Research and Development	N/A
Completed	Translating Extinction Research to Improve Pharmacotherapy for Tobacco Dependence NCT02202499	H. Lee Moffitt Cancer Center and Research Institute	EARLY_Phase 1
Completed	The PROMPT Pilot Study NCT03626064	Ottawa Hospital Research Institute	N/A
Withdrawn	cSBI-M for Young Military Personnel NCT01847300	Boston Children's Hospital	N/A
Completed	Project 1, Study 1: Investigating the Impact of Nicotine Using Spectrum Cigarettes NCT01681875	Wake Forest University Health Sciences	N/A
Completed	Improving Health for Aboriginal People Through Tobacco Related Research NCT01735448	The Queen Elizabeth Hospital	—
Completed	Studying the Effects of Administration of Polyunsaturated Fatty Acids (PUFAS) of Omega-3 Series in Nicotine De NCT01735279	Federal University of São Paulo	Phase 3
Unknown	Effectiveness of an E-mail Tracking Intervention Among the Continued Abstinence of Tobacco Consumption NCT01494246	Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina	Phase 4
Completed	Web Assisted Tobacco Intervention With Community Colleges NCT01692730	University of Rochester	N/A
Unknown	tDCS as Add on Therapy for Treatment of Tobacco Dependence by Standardized Behaviour Therapy NCT01729507	Ludwig-Maximilians - University of Munich	Phase 4
Completed	Yoga as a Complementary Therapy for Smoking Cessation NCT01809678	The Miriam Hospital	N/A
Completed	Acute Effects of Exercise in Smokers With Schizophrenia NCT01635075	Brown University	Phase 2
Completed	New Hampshire Medicaid Wellness Incentive Program NCT02515981	Dartmouth-Hitchcock Medical Center	N/A
Terminated	Tobacco Dependence in Breast Cancer Patients Trial of Varenicline (Chantix) NCT01532232	Memorial Sloan Kettering Cancer Center	—
Completed	An Exploratory Study Comparing Two Nicotine Inhalers NCT01478230	McNeil AB	EARLY_Phase 1
Completed	Study to Evaluate the Safety and Efficacy of Dietary Supplement Anatabloc in Reducing Daily Smokers' Urge to S NCT01428310	Rock Creek Pharmaceuticals, Inc.	Phase 1
Completed	Positively Smoke Free on the Web (PSFW) for Smokers Living With HIV NCT01570595	Georgetown University	Phase 1 / Phase 2
Completed	System Based Tracking and Treatment for Emergency Patients Who Smoke: STTEPS NCT01839903	The Miriam Hospital	N/A
Completed	Tailoring Varenicline to Individual Needs (TVIN Study) NCT01206010	Queen Mary University of London	Phase 3
Completed	De-nicotinised Cigarettes Study NCT01250301	Queen Mary University of London	N/A
Completed	Varenicline Treatment for Active Alcoholic Smokers NCT01347112	Mayo Clinic	Phase 2 / Phase 3
Completed	Nicotine Pharmacodynamics With a New Oral Nicotine Replacement Therapy and Nicotine Gum NCT01368016	McNeil AB	N/A
Completed	Combination of Nicotine Replacement Therapy (NRT) and Varenicline to Increase Cessation of Tobacco (CONVICT St NCT01184664	Queen Mary University of London	Phase 3
Completed	Tobacco Intervention in Buprenorphine Treatment NCT01350011	University of California, San Francisco	Phase 3
Completed	A Study of Novel Smoking Cessation Interventions in Current and Former Injection Drug Users NCT01334736	Johns Hopkins University	N/A
Completed	Varenicline in Combination With Nicotine Replacement Therapy for Smoking Cessation NCT01444131	University of Stellenbosch	Phase 2
Terminated	Study to Determine if a New Nicotine Replacement Therapy Can Safely Help Smokers to Quit Smoking NCT01296698	McNeil Consumer Healthcare Division of McNEIL-PPC, Inc.	Phase 3
Completed	Multiple-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Products NCT01321931	McNeil AB	Phase 1
Completed	Virtual Clinician Research Tool NCT01408758	University of Rochester	N/A
Completed	Tobacco Cessation Interventions With Ohio Appalachian Smokers NCT02695225	Ohio State University	N/A
Completed	Single-dose Nicotine Pharmacokinetics With Four Oral Nicotine Replacement Products NCT01234896	McNeil AB	N/A
Completed	Novel Determinants and Measures of Smokeless Tobacco Use: Study 1 NCT01067586	University of Minnesota	—
Completed	Bioequivalence Between an Oral Nicotine Replacement Product and Nicorette® Gum NCT01152749	McNeil AB	N/A
Completed	Tobacco Dependence Treatment for Asian Americans NCT01091363	University of Massachusetts, Boston	N/A
Completed	Changing Thought and Action in Tobacco Dependence With Transcranial Magnetic Stimulation NCT00973622	University of Arkansas	N/A
Completed	Efficacy and Safety of Varenicline Among HIV-infected Patients NCT00918307	ANRS, Emerging Infectious Diseases	Phase 3
Completed	Evaluation of Tobacco Treatment Strategies for Inpatient Psychiatry NCT00968513	Stanford University	N/A
Unknown	Varenicline for Long-term Nicotine Replacement Therapy (NRT) Users NCT00977249	University Hospital, Gentofte, Copenhagen	Phase 2 / Phase 3
Completed	Comparative Pharmacokinetic Study of New Oral Nicotine Replacement Therapy Products. NCT01227720	McNeil AB	N/A
Completed	Direct to Smoker Outreach in a Health Care Setting NCT01321944	Massachusetts General Hospital	N/A
Completed	Use of Varenicline for 4-weeks Prior to Quitting NCT00789074	Queen Mary University of London	Phase 3
Completed	Single-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product NCT01084603	McNeil AB	N/A
Completed	Evaluation of the Safety Profile, Quit and Reduction Rate After Nicorette® Gum and Patch Treatment NCT00749463	McNeil AB	Phase 4
Completed	Multiple-dose Nicotine Pharmacokinetics With a New Oral Nicotine Replacement Product. NCT01084707	McNeil AB	N/A
Completed	Nicotine Lozenge or Tobacco-Free Snuff for Smokeless Tobacco Reduction NCT01018394	Mayo Clinic	Phase 2 / Phase 3
Completed	Pharmacokinetics With a New Oral Nicotine Replacement Product and Nicorette® Gum NCT01152736	McNeil AB	N/A
Completed	Effect of Varenicline on Reactivity to Smoking and Drinking Cues NCT00873535	Centre for Addiction and Mental Health	N/A
Completed	Bioequivalence Between Nicotine Replacement Products and Nicorette® Gum NCT01113424	McNeil AB	N/A
Completed	Varenicline Effects on Cue Reactivity and Smoking Reward/Reinforcement NCT00747643	H. Lee Moffitt Cancer Center and Research Institute	N/A
Completed	S-Adenosyl-L-Methionine (SAMe) for Smoking Abstinence NCT00722124	Mayo Clinic	Phase 2 / Phase 3
Completed	Bioequivalence Between Two New Oral Nicotine Replacement Therapy Products and Nicorette® Microtab NCT01238640	McNeil AB	N/A
Completed	Single-dose Nicotine Pharmacokinetics With Three Oral Nicotine Replacement Products. A Study in Healthy Smoker NCT01234792	McNeil AB	N/A
Completed	Pharmacokinetics With Two New Oral Nicotine Replacement Products and Nicorette® Gum NCT01152723	McNeil AB	N/A
Completed	Bioequivalence Between Two Oral Nicotine Sublingual Tablets, 2 mg and 4 mg NCT01238627	McNeil AB	N/A
Completed	Single-dose Pharmacokinetics of Oral Nicotine Replacement Products NCT01228617	Johnson & Johnson Consumer and Personal Products Worldwide	N/A
Completed	Effects of Yoga and Cardiovascular Exercise on Smoking Motivation NCT01423578	H. Lee Moffitt Cancer Center and Research Institute	N/A
Completed	Quitline Use in Surgical Patients NCT00656500	Mayo Clinic	N/A
Completed	Behavioral Therapy for Reduction in Smoking Craving NCT00449293	University of Pittsburgh	N/A
Completed	Topiramate Alone and in Combination With the Nicotine Patch for Smoking Cessation: A Pilot Study NCT00755716	UConn Health	Phase 3
Unknown	Smoking Cessation With Smokeless Tobacco, Nicotine Tablets and Nicotine Patches NCT00313105	University Hospital, Gentofte, Copenhagen	Phase 2 / Phase 3
Completed	The Pharmacogenetic Study , Readiness to Change, and Pharmacological Intervention for Smoking Cessation in Sch NCT00495352	Yu-Li Hospital	Phase 4
Completed	Reducing Ethnic Health Disparities: Motivating HIV+ Latinos to Quit Smoking NCT00503230	Butler Hospital	Phase 3
Completed	A Study on the Effects of Two Nicotine Replacement Products on Tooth Staining NCT01440985	McNeil AB	N/A
Completed	Randomized Trial of Ultrashort Psychotherapy vs Sustained-Release Bupropion for Smoking Cessation NCT00484692	Medical University Innsbruck	Phase 4
Completed	Use of Pharmacotherapy to Reduce Cue-responsiveness in Smokers NCT00133757	Centre for Addiction and Mental Health	Phase 1
Completed	Prolonged Smoking Cessation Using Prescription Step Care NCT00170079	University of Tennessee	N/A
Completed	Comparisons of Nicotine-free Cigarettes, Extra Low Nicotine Cigarettes vs. Medicinal Nicotine NCT00777569	National Institute on Drug Abuse (NIDA)	Phase 2
Completed	Predictors of Treatment Outcome for Smokers With and Without Schizophrenia NCT00501007	Rutgers, The State University of New Jersey	—
Terminated	Efficacy and Safety of Bupropion for Treatment of Adolescent Smoking NCT00248118	National Institute on Drug Abuse (NIDA)	Phase 2 / Phase 3
Completed	Smoking Cessation Intervention: Effectiveness in Primary Care NCT00296647	University of Wisconsin, Madison	Phase 4
Completed	Effects of Naltrexone on Nicotine Reinforcement NCT00270231	University of Pennsylvania	Phase 2
Completed	Emergency Department Telephone Quitline NCT00394420	Mayo Clinic	N/A
Terminated	Physical Activity as an Aid for Smoking Cessation NCT00521391	University of Lausanne Hospitals	Phase 3
Completed	Bupropion Alone or Combined With Nicotine Gum NCT01621022	University of Wisconsin, Madison	Phase 4
Completed	Bupropion SR Plus Counseling for Smoking Cessation NCT01621009	University of Wisconsin, Madison	Phase 4
Completed	ROSCAP: Reduction of Smoking in Cardiac Patients Study NCT00301626	National Institutes of Health (NIH)	N/A
Completed	Safety, Tolerability and Efficacy of the Nicotine Patch and Gum for the Treatment of Adolescent Tobacco Depend NCT01208935	National Institute on Drug Abuse (NIDA)	Phase 2 / Phase 3
Completed	Provider and Peer Delivered Youth Smoking Intervention NCT00435344	University of Massachusetts, Worcester	Phase 2