Clinical Trials Directory

Trials / Conditions / Thalassemia

Thalassemia

147 registered clinical trials studyying Thalassemia21 currently recruiting.

StatusTrialSponsorPhase
Not Yet RecruitingEvaluation of the Quality of Life in Patients With Chronic Iron Overload Due to Hemoglobinopathies in Greece.
NCT07352878
Elpen Pharmaceutical Co. Inc.
RecruitingA Real-World Study to Evaluate Luspatercept in Adults With Transfusion-Dependent Beta-Thalassemia in the Middl
NCT07215975
Bristol-Myers Squibb
CompletedA Study on the Effect of Etavopivat on Heart Rhythm in Healthy Participants
NCT07023029
Novo Nordisk A/SPhase 1
RecruitingA Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassa
NCT06609226
Novo Nordisk A/SPhase 3
RecruitingEffect of Exercise on Body Composition and Bone Health in Patients With Thalassemia
NCT07064941
University of California, San FranciscoN/A
Active Not RecruitingDevelopment of THALEA Kit and Its Impact on Knowledge, Attitude, and Intention for Premarital Thalassemia Scre
NCT06800495
Universiti Teknologi MaraN/A
CompletedA Research Study Looking at a Single Dose of Etavopivat in Healthy Chinese Participants
NCT06581627
Novo Nordisk A/SPhase 1
Not Yet RecruitingEffect of Folic Acid Supplementation in Pregnant Women Having Thalassaemia Trait
NCT04310059
The University of Hong KongN/A
Not Yet RecruitingEKLF Gene Expression in β-thalassemia
NCT06440603
Rofaida Hassan Ahmed
RecruitingEvaluating Safety and Efficacy of Lentiviral-transduced CD34+ HSCs in Β-thalassaemia Patients.
NCT06655662
Shenzhen HemogenPhase 1
RecruitingA Study of Safety and Efficiency of AND017 in Patients With β-thalassemia
NCT06302491
Kind Pharmaceuticals LLCPhase 2
CompletedImpact of Virtual Reality on Pain and Anxiety During Intravenous Cannulation Procedures Among Thalassemia Pati
NCT07099196
Mohammed Bin Rashid University of Medicine and Health SciencesN/A
RecruitingDetermination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling
NCT06313398
National Heart, Lung, and Blood Institute (NHLBI)EARLY_Phase 1
RecruitingA Phase 1 Study of Gene-modified Autologous Hematopoietic Stem Cell (BD211) Treating β-thalassemia Major
NCT06465550
Shanghai BDgene Co., Ltd.Phase 1
UnknownAssessment of Cognitive Function and Quality of Life in Thalassemic Children at Sohag University Hospital
NCT06058260
Sohag University
RecruitingSafety and Efficacy of Gene Modified Autologous Hematopoietic Stem Cells to Treat Transfusion-dependent Beta-t
NCT05773729
Shanghai BDgene Co., Ltd.N/A
CompletedEffect of L-Glutamine on Pulmonary Artery Pressure in Patients With Non-Transfusion-Dependent Thalassemia
NCT07210450
Mazandaran University of Medical SciencesPhase 2 / Phase 3
CompletedPregnancy and Childbirth in Women with Thalassemia Yesterday and Today
NCT06889727
Fondazione per la Ricerca sulle Anemie ed Emoglobinopatie in Italia
CompletedSafety and Efficacy of Immunomodulator Drug Thalidomide in Multi-transfused Thalassemia Patients
NCT06888232
Muhammad Aamir LatifN/A
UnknownAssessment of Quality of Life in Thalassemic Patients at Assiut University Hospital: A Single-center Experienc
NCT05790980
Assiut University
CompletedPharmacotherapy Prescribing Pattern and the Adherence Level to Iron Chelation Therapy in Thalassemia
NCT06210139
Reem Ali Shaker
RecruitingA Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to
NCT05736419
Memorial Sloan Kettering Cancer CenterPhase 2
Recruitingthe Safety and Efficacy Evaluation of HGI-002 Injection in Patients With Transfusion-Dependent α-Thalassemia
NCT05851105
Shenzhen HemogenEARLY_Phase 1
RecruitingAtrial Fibrillation in Beta-Thalassemia
NCT05508932
University Hospital of Ferrara
RecruitingEvaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thal
NCT05477563
Vertex Pharmaceuticals IncorporatedPhase 3
UnknownCorrelation Between Pulmonary Functions and Physical Fitness in Children With β-thalassemia
NCT05494333
Cairo University
RecruitingEuropean Rare Blood Disorders Platform (ENROL)
NCT06250595
Hospital Universitari Vall d'Hebron Research Institute
CompletedLong-term Clinical Study of CN128 in Thalassemia With Sever Liver Iron Overloaded Patients
NCT05355766
Hangzhou Zede Pharma-Tech Co., Ltd.Phase 2
CompletedInhibitory Effect of a Polyphenol Supplement on Dietary Iron Absorption in Adults with Thalassemia
NCT05326503
Swiss Federal Institute of TechnologyN/A
Recruitingthe Safety and Efficacy Evaluation of HGI-001 Injection in Patients With Transfusion-Dependent β-Thalassemia
NCT05864170
Shenzhen HemogenEARLY_Phase 1
Active Not RecruitingEvaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Transfusion-Dependent β-Thalassemia
NCT05356195
Vertex Pharmaceuticals IncorporatedPhase 3
CompletedA Study of Etavopivat in Patients With Thalassemia or Sickle Cell Disease
NCT04987489
Forma Therapeutics, Inc.Phase 2
CompletedRed Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients
NCT05255445
Westat
RecruitingRADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs)
NCT06213402
Hospital Universitari Vall d'Hebron Research Institute
UnknownThalassemia Knowledge in Young People of Indonesia
NCT04706585
Fakultas Kedokteran Universitas Indonesia
Enrolling By InvitationA Long-term Follow-up Study in Participants Who Received CTX001
NCT04208529
Vertex Pharmaceuticals IncorporatedPhase 3
RecruitingSafety and Efficacy Evaluation of β-globin Restored Autologous Hematopoietic Stem Cells in β-thalassemia Major
NCT05745532
Shenzhen HemogenEARLY_Phase 1
TerminatedA Study of IMR-687 in Subjects With Beta Thalassemia
NCT04411082
Cardurion Pharmaceuticals, Inc.Phase 2
CompletedAssessment of Nutritional Status and Role of Insulin-like Growth Factor-1 in Children
NCT05529550
Menoufia University
CompletedLong-term Clinical Study of CN128 in Thalassemia Patients
NCT04614779
Hangzhou Zede Pharma-Tech Co., Ltd.Phase 2
RecruitingATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders
NCT04398628
American Thrombosis and Hemostasis Network
CompletedThe Role of OCTA in Patients Affected by Beta Thalassemia
NCT04582110
Federico II University
TerminatedHydroxyurea Therapy: Optimizing Access in Pediatric Populations Everywhere
NCT03825341
St. Jude Children's Research HospitalPhase 2
CompletedSafety Study for Beta Thalassemia Subjects on PTG-300
NCT04054921
Protagonist Therapeutics, Inc.Phase 2
Active Not RecruitingA Study to Determine the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AG-348 in Adult Participa
NCT03692052
Agios Pharmaceuticals, Inc.Phase 2
Active Not RecruitingA Blood Stem Cell Transplant for Sickle Cell Disease
NCT03249831
City of Hope Medical CenterPhase 1
UnknowniHSCs With the Gene Correction of HBB Intervent Subjests With β-thalassemia Mutations
NCT03728322
Allife Medical Science and Technology Co., Ltd.EARLY_Phase 1
CompletedStudy of PTG-300 in Non-Transfusion Dependent and Transfusion-Dependent Beta-Thalassemia Subjects With Chronic
NCT03802201
Protagonist Therapeutics, Inc.Phase 2
CompletedShort-term Clinical Study of CN128 in Thalassemia Patients
NCT03935633
Hangzhou Zede Pharma-Tech Co., Ltd.Phase 1
CompletedA Safety and Efficacy Study Evaluating CTX001 in Participants With Transfusion-Dependent β-Thalassemia
NCT03655678
Vertex Pharmaceuticals IncorporatedPhase 2 / Phase 3
CompletedAdiponectin, IL-6 and hsC-RP in Relation to Carotid Intima-media Thickness in B-thalassemia Patients
NCT03170245
Assiut University
CompletedCerebrovascular Reserve and White Matter Disease in Patients with Chronic Anemia
NCT03715972
Children's Hospital Los Angeles
TerminatedHaploidentical Allogeneic Hematopoietic Stem Cell Transplantation (HaploHCT) Following Reduced Intensity Condi
NCT03367546
Masonic Cancer Center, University of MinnesotaPhase 2
CompletedConditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation
NCT03513328
University of FloridaPhase 1 / Phase 2
CompletedImmunomodulatory Vitamin D in Thalassemia
NCT03919812
Universitas PadjadjaranN/A
UnknownColla Corii Asini Treating Anemia in Pregnant Women With Thalassemia(Presenting the Syndrome of Blood Deficien
NCT03374111
The First Affiliated Hospital, Guangzhou University of Traditional Chinese MedicinePhase 4
CompletedA Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)
NCT03342404
CelgenePhase 2
CompletedClinical Study of CN128 in Thalassemia Patients
NCT03673085
Hangzhou Zede Pharma-Tech Co., Ltd.Phase 1
CompletedEfficacy and Safety of Low Dose Thalidomide in Transfusion Dependent Thalassemia
NCT03651102
Blood Diseases ClinicPhase 2 / Phase 3
TerminatedFludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Pa
NCT03333486
Roswell Park Cancer InstitutePhase 2
UnknownStudy on the Mechanism of Colla Corri Asini in the Treatment of Thalassemia Patients With Pregnancy Anemia
NCT03392298
The First Affiliated Hospital, Guangzhou University of Traditional Chinese MedicinePhase 4
UnknownQuality of Life and Treatment Satisfaction in β-Thalassemia Patients Receiving Deferasirox
NCT03358498
Assiut University
CompletedStudy of Thiotepa and TEPA Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients
NCT03609840
University of California, San Francisco
CompletedSafety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISIS 702843 Administered Subcutaneously to Hea
NCT03165864
Ionis Pharmaceuticals, Inc.Phase 1
UnknownThe Effective and Safety of Thalidomide in TI
NCT03184844
Xiao-Lin YinPhase 2
CompletedSofosbuvir/Ledipasvir for Hepatitis C Genotype 1-6 in Patients With Transfusion-Dependent Thalassemia: An Open
NCT03032666
Ala'a ShararaPhase 4
CompletedHemoglobinopathy Nursing Program and Pediatric Nursing Students
NCT05389891
Beni-Suef UniversityN/A
TerminatedLong Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study
NCT03733249
Bellicum PharmaceuticalsPhase 1 / Phase 2
UnknownThe Effective and Safety of Thalidomide in NTDT
NCT02995707
Xiao-Lin YinPhase 2
UnknownL-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension
NCT03402191
Sherief Abd-ElsalamPhase 4
TerminatedAllogeneic SCT of CordIn™, in Patients With Hemoglobinopathies
NCT02504619
Gamida Cell ltdPhase 1 / Phase 2
CompletedStudy of Clofarabine and Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation (HCT)
NCT03609814
University of California, San Francisco
CompletedThe Prevalence and Severity of HCV Infection in Thalassemia Major and Thalassemia Intermedia in Siriraj Hospit
NCT02904252
Mahidol University
CompletedStudy of Melphalan Drug Exposure in Pediatric Hematopoietic Stem Cell Transplant Patients
NCT03609827
University of California, San Francisco
Active Not RecruitingCINC424A2X01B Rollover Protocol
NCT02386800
Novartis PharmaceuticalsPhase 4
UnknownTherapeutic Effect of Colla Corii Asini on Improving Anemia and Hemoglobin Composition in Pregnant Women With
NCT02772016
Yanfang LiEARLY_Phase 1
CompletedHaploidentical Hematopoietic Stem Cell Transplantation
NCT02165007
Catherine BollardPhase 1
CompletedExtension Study to Evaluate the Safety and Efficacy of Luspatercept in Participants With β-Thalassemia Previou
NCT02268409
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USAPhase 2
CompletedUse of Mobile Technology for Intensive Training in Medication Management
NCT02133560
Duke UniversityN/A
Active Not RecruitingNonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disea
NCT02105766
National Heart, Lung, and Blood Institute (NHLBI)Phase 2
TerminatedSafety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell Transplant
NCT02065869
Bellicum PharmaceuticalsPhase 1 / Phase 2
CompletedAmlodipine for Myocardial Iron in Thalassemia
NCT02065492
Aga Khan UniversityPhase 2 / Phase 3
UnknownA Case Control Study to Evaluate the Cognitive and Brain Function of β-thalassemia Patients.
NCT01935661
HaEmek Medical Center, Israel
CompletedPneumococcal Vaccination for Splenectomised Thalassemia Major Patients in Indonesia
NCT03095326
Fakultas Kedokteran Universitas IndonesiaPhase 4
CompletedZinc Supplementation on Cellular Immunity in Thalassemia Major
NCT03117192
Fakultas Kedokteran Universitas IndonesiaPhase 4
CompletedBone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders
NCT01758042
Massachusetts General HospitalN/A
CompletedZinc and Diabetes in Patients With Thalassemia: a Pilot Study
NCT01772680
UCSF Benioff Children's Hospital OaklandN/A
CompletedAmlodipine in the Prevention and Treatment of Iron Overload in Patients With Thalassemia Major
NCT01395199
University of Campinas, BrazilPhase 3
CompletedMulticenter Observational Study on Myocardial Iron Overload in 3 Multitransfused Populations
NCT01911871
Assistance Publique - Hôpitaux de Paris
TerminatedEffects of Transfusion of Older Stored Red Cells
NCT01534676
Columbia UniversityN/A
CompletedDemographic, Clinical, Laboratory and Genetical Characteristics of Patients With Beta Thalassemia Intermedia
NCT01443312
HaEmek Medical Center, Israel
CompletedStudy of Effects of YisuiShengxueGranules on Thalassemia
NCT01549080
Guang'anmen Hospital of China Academy of Chinese Medical Sciences
WithdrawnPhase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies
NCT01419704
Talaris Therapeutics Inc.Phase 1 / Phase 2
CompletedRenal Function Among Thalassemia Patients Treated by a Oral Chelator Deferasirox
NCT01905774
HaEmek Medical Center, Israel
CompletedStudy of Fludarabine Drug Exposure in Pediatric Bone Marrow Transplantation
NCT01316549
University of California, San Francisco
CompletedGenes Influencing Iron Overload State
NCT01158794
St. Jude Children's Research Hospital
TerminatedAlefacept and Allogeneic Hematopoietic Stem Cell Transplantation
NCT01319851
Emory UniversityN/A
CompletedMulti-Center Study of Iron Overload: Survey Study (MCSIO)
NCT01913548
UCSF Benioff Children's Hospital Oakland
CompletedEfficacy and Safety of Desferal Versus Osveral in Transfusional Iron Overload
NCT01369719
Hormozgan University of Medical SciencesN/A
CompletedThis Study Will Evaluate Efficacy and Safety of Deferasirox in Patients With Myelodysplastic Syndromes (MDS),
NCT01250951
Novartis PharmaceuticalsPhase 4
CompletedMulti-Center Study of Iron Overload: Pilot Study
NCT01114776
UCSF Benioff Children's Hospital Oakland
CompletedAssessment of Pain in People With Thalassemia Who Are Treated With Regular Blood Transfusions
NCT00872833
Carelon Research
CompletedEffect of Antioxidant Cocktail in Beta-thalassemia/Hb E Patients
NCT01597765
Mahidol UniversityN/A
CompletedBlood Transfusions in Thalassemia Patients, Complications and Adverse Effects
NCT00971880
HaEmek Medical Center, Israel
CompletedGlutamine Therapy for Hemolysis-Associated Pulmonary Hypertension
NCT01048905
UCSF Benioff Children's Hospital OaklandPhase 2
CompletedAllo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity C
NCT00957931
Stanford UniversityPhase 2
CompletedAssessment of Pain in People With Thalassemia
NCT00872339
Carelon Research
CompletedSildenafil to Improve Exercise Capacity in People With Thalassemia and Pulmonary Hypertension
NCT00872170
Carelon ResearchPhase 2 / Phase 3
CompletedThe Spleen in Sickle Cell Anemia and Sickle Cell Thalassemia
NCT00971698
HaEmek Medical Center, Israel
CompletedIron Overload and Growth Velocity in Thalassemia and Sickle Cell Anemia
NCT00972231
HaEmek Medical Center, Israel
CompletedReduced Intensity Conditioning for Umbilical Cord Blood Transplant in Pediatric Patients With Non-Malignant Di
NCT00744692
Duke UniversityPhase 1
CompletedUnrelated Hematopoietic Stem Cell Transplantation(HSCT) for Genetic Diseases of Blood Cells
NCT00730314
Children's Hospital Los AngelesPhase 1 / Phase 2
UnknownIron Balance Study of Deferasirox, Deferoxamine and the Combination of Both
NCT00738413
Weill Medical College of Cornell UniversityPhase 1 / Phase 2
CompletedOral Nifedipine to Treat Iron Overload
NCT00712738
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Phase 1
CompletedBone Marrow for Hemoglobinopathy Research
NCT00669305
St. Jude Children's Research Hospital
CompletedSickle Cell Anemia Screening and Prevention in Northern Israel
NCT00735488
HaEmek Medical Center, Israel
CompletedClinical Diagnosis of Teenagers Admitted to Pediatric Departments
NCT00735540
HaEmek Medical Center, Israel
CompletedEvaluating the Safety and Effectiveness of Decitabine in People With Thalassemia Intermedia
NCT00661726
Carelon ResearchPhase 2
CompletedCombined Chelation Therapy in Patients With Transfusion Dependent Thalassemia and Iron Overload
NCT00901199
Elliott VichinskyPhase 2
CompletedPhase I Study to Examine the Effect of Deferasirox on Renal Hemodynamics in β-thalassemia Patients With Transf
NCT00560820
Novartis PharmaceuticalsPhase 1
CompletedEvaluating People With Thalassemia: The Thalassemia Longitudinal Cohort (TLC) Study
NCT00661804
Carelon Research
CompletedEndocrine and Nutritional Assessment in B Thalassemia Major
NCT00456690
HaEmek Medical Center, IsraelN/A
CompletedPegasys® Plus Ribavirin in Thalassemic Patients With Hepatitis C Virus Infection
NCT00707850
Baqiyatallah Medical Sciences UniversityPhase 4
UnknownDetection of β Thalassemia Carriers by Red Cell Parameters Obtained From the H2 Automatic Counter
NCT00481221
HaEmek Medical Center, Israel
TerminatedRelated Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood Cells
NCT02512679
Children's Hospital Los AngelesPhase 2
CompletedT2* in Transfusion Dependant Anemia, MI, LVF, Normal Patients
NCT00520559
Imperial College London
CompletedThe Change of Coagulation Markers in Children With β-thalassemia Disease After Stem Cell Transplantation
NCT00789516
Mahidol University
CompletedZinc & Bone Health in Thalassemia: The Think Zinc Study
NCT00459732
UCSF Benioff Children's Hospital OaklandN/A
CompletedInvasive Infections in Children With Hemoglobinopathies
NCT00456443
HaEmek Medical Center, Israel
CompletedExpanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overl
NCT00235391
Novartis PharmaceuticalsPhase 3
UnknownFactors Promoting Increased Rate and Success of Pregnancy in the Thalassemia Population in Toronto
NCT00327639
University Health Network, Toronto
CompletedL-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia
NCT00125788
Emmaus Medical, Inc.Phase 2
CompletedEvaluation of Efficacy of Zoledronic Acid in Patients With Haemoglobin Syndromes (Thalassemia and Sicle Cell A
NCT00346242
Novartis PharmaceuticalsPhase 4
CompletedAllogeneic Stem Cell Transplantation Following Chemotherapy in Patients With Hemoglobinopathies
NCT00153985
Dana-Farber Cancer InstitutePhase 2
TerminatedL-Glutamine Therapy for Sickle Cell Anemia
NCT00586209
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterPhase 2
TerminatedAllogeneic Stem Cell Transplantation, Severe Homzygous 0/+Thalassemia or Sever Variants of Beta 0/+ Thalassemi
NCT00578292
Baylor College of MedicineN/A
CompletedEvaluating the Safety of Two Medications to Treat Hepatitis C in People With Thalassemia (The HepC Study)
NCT00502788
Carelon ResearchPhase 2
CompletedA Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative Regime
NCT00427661
University of PittsburghN/A
CompletedStem Cell Transplant for Hemoglobinopathy
NCT00176852
Masonic Cancer Center, University of MinnesotaPhase 2 / Phase 3
TerminatedStem Cell Transplantation After Reduced-Dose Chemotherapy for Patients With Sickle Cell Disease or Thalassemia
NCT00034528
National Institute of Allergy and Infectious Diseases (NIAID)Phase 2
TerminatedBone Marrow Transplant From Donor Using Less Toxic Conditioning for Patient With High Risk Hemoglobinopathies
NCT00040417
Baylor College of MedicinePhase 2
TerminatedBone Marrow Transplant From Related Donor for Patients With High Risk Hemoglobinopathies
NCT00040469
Baylor College of MedicinePhase 2
CompletedThalassemia (Cooley's Anemia) Clinical Research Network (TCRN)
NCT00000623
Carelon Research
CompletedCombination Iron Chelation Therapy
NCT00004982
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Phase 1
CompletedChelation Therapy of Iron Overload With Pyridoxal Isonicotinoyl Hydrazone
NCT00000588
Case Western Reserve UniversityPhase 2
CompletedDeferoxamine for the Treatment of Hemochromatosis
NCT00001203
National Heart, Lung, and Blood Institute (NHLBI)
CompletedEvaluation of Subcutaneous Desferrioxamine as Treatment for Transfusional Hemochromatosis
NCT00000595
National Heart, Lung, and Blood Institute (NHLBI)Phase 2