| Terminated | A Study of MK-2225 / ACE-1334 in Participants With Systemic Sclerosis With and Without Interstitial Lung Disea Systemic Sclerosis With and Without Interstitial Lung Disease | Phase 1 | 2023-03-10 |
| Completed | Study of Sotatercept in Newly Diagnosed Intermediate- and High-Risk PAH Participants (MK-7962-005/A011-13) Pulmonary Arterial Hypertension | Phase 3 | 2022-03-18 |
| Completed | A Study of Sotatercept for the Treatment of Cpc-PH Due to HFpEF (MK-7962-007/A011-16) Hypertension, Pulmonary | Phase 2 | 2021-12-29 |
| Completed | A Study of Sotatercept in Participants With PAH WHO FC III or FC IV at High Risk of Mortality (MK-7962-006/ZEN Pulmonary Arterial Hypertension | Phase 3 | 2021-12-01 |
| Completed | A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR) Pulmonary Arterial Hypertension | Phase 3 | 2021-01-25 |
| Terminated | Extension Study to Evaluate the Long-Term Effects of ACE-083 in Patients With Facioscapulohumeral Muscular Dys Facioscapulohumeral Muscular Dystrophy, Charcot-Marie-Tooth Disease | Phase 2 | 2019-05-10 |
| Completed | A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension Pulmonary Arterial Hypertension | Phase 2 | 2019-04-19 |
| Completed | A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (PAH) Pulmonary Arterial Hypertension | Phase 2 | 2018-06-13 |
| Completed | A Study of ACE-2494 in Healthy Subjects Healthy Volunteers | Phase 1 | 2018-02-15 |
| Terminated | Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease Charcot-Marie-Tooth Disease | Phase 2 | 2017-07-31 |
| Terminated | Study of ACE-083 in Patients With Facioscapulohumeral Muscular Dystrophy (FSHD) Facioscapulohumeral Muscular Dystrophy | Phase 2 | 2016-11-01 |
| Completed | Extension Study to Evaluate the Safety and Efficacy of Luspatercept in Participants With β-Thalassemia Previou β-Thalassemia | Phase 2 | 2014-10-20 |
| Completed | Extension Study to Evaluate Long-Term Effects of Luspatercept in Patients With Myelodysplastic Syndromes (MDS) Myelodysplastic Syndromes | Phase 2 | 2014-10-09 |
| Completed | Phase 1 Study of ACE-083 in Healthy Subjects Musculoskeletal Diseases | Phase 1 | 2014-09-01 |
| Completed | Study of Dalantercept and Sorafenib in Patients With Advanced Hepatocellular Carcinoma Advanced Adult Hepatocellular Carcinoma | Phase 1 / Phase 2 | 2014-08-04 |
| Completed | Study to Evaluate the Safety and Efficacy of Luspatercept (ACE-536) in Participants With Beta-thalassemia (A53 B-Thalassemia | Phase 2 | 2013-02-28 |
| Completed | Study of Luspatercept for the Treatment of Anemia in Patients With Myelodysplastic Syndrome (MDS) (MK-6143-001 Anemia | Phase 2 | 2013-01-21 |
| Terminated | Study of Dalantercept and Axitinib in Patients With Advanced Renal Cell Carcinoma Advanced Renal Cell Carcinoma | Phase 2 | 2012-12-01 |
| Completed | Study of Dalantercept in Patients With Squamous Cell Carcinoma of the Head and Neck Squamous Cell Carcinoma of the Head and Neck | Phase 2 | 2011-10-01 |
| Completed | Study of ACE-536 in Healthy Postmenopausal Women Anemia | Phase 1 | 2011-09-01 |
| Terminated | Extension Study of ACE-031 in Subjects With Duchenne Muscular Dystrophy Duchenne Muscular Dystrophy | Phase 2 | 2010-10-01 |
| Terminated | Study of ACE-031 in Subjects With Duchenne Muscular Dystrophy Duchenne Muscular Dystrophy | Phase 2 | 2010-04-01 |
| Completed | Study of ACE-041 in Patients With Advanced Solid Tumors or Relapsed/Refractory Multiple Myeloma Advanced Solid Tumors, Multiple Myeloma | Phase 1 | 2009-10-01 |
| Completed | A Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ACE-031 in Healthy Postmenopausal Women Muscular Atrophy | Phase 1 | 2009-08-01 |
| Completed | A Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ACE-031 (ActRIIB-IgG1)in Healthy Postmeno Muscle Loss | Phase 1 | 2008-09-01 |
| Completed | A Safety, Tolerability and Pharmacodynamics Study of ACE-011 (ActRIIA-IgG1) in Healthy Postmenopausal Women Osteoporosis | Phase 1 | 2008-01-01 |