NCT01369719

Efficacy and Safety of Desferal Versus Osveral in Transfusional Iron Overload

Efficacy and Safety of Desferal Versus Osveral in Transfusional Iron Overload Patients With β-Thalassemia and Intermediate Thalassemia in Bandarabbas

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 138 (actual)
• Sponsor: Hormozgan University of Medical Sciences · Academic / Other
• Sex: All
• Age: 2 Years
• Healthy volunteers: Not accepted

Summary

Thalassemic patients often suffer from iron overload due to frequent blood transfusion. Oral iron chelators reduce iron overload in transfusion dependent patients. The aim of this study is to compare the efficacy and safety of osveral and desferal in transfusional iron overload patients with β-Thalassemia and intermediate Thalassemia in Bandarabbas.

Detailed description

This is a double blinded randomized controlled trial on Efficacy and safety of Osveral and Desferal in thalassemic patients.

Conditions

• Thalassemia
• Iron Overload
• Transfusion Related Complications

Interventions

Type	Name	Description
DRUG	osveral	receive 20 mg/kg daily orally
DRUG	Desferal	40-50mg/Kg for 6 nights in each week subcutaneously

Timeline

• Start date: 2010-02-01
• Primary completion: 2011-01-01
• Completion: 2011-05-01
• First posted: 2011-06-09
• Last updated: 2011-06-14

Locations

1 site across 1 country: Iran